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phts (14) 14
index medicus (11) 11
humans (10) 10
pten (10) 10
cancer (9) 9
cowden syndrome (9) 9
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hamartoma syndrome, multiple - genetics (6) 6
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development and progression (3) 3
expression (3) 3
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germline pten (3) 3
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germline mutations (2) 2
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hamartoma syndrome, multiple - pathology (2) 2
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health aspects (2) 2
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peutz-jeghers syndrome (2) 2
peutz-jeghers-syndrome (2) 2
phosphatase (2) 2
phosphatase and tensin homolog hamartoma tumor syndrome (2) 2
phosphatase-activity (2) 2
phosphatases (2) 2
phts, pten hamartoma tumor syndrome (2) 2
pi3k (2) 2
pjs (2) 2
polymerase proofreading-associated polyposis (2) 2
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Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. 607 - 620.e15
Background Patients with heterozygous germline mutations in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) experience autoimmunity and lymphoid... 
Allergy and Immunology | PHTS | autoimmunity | immunologic synapse | PTEN | Regulatory T cells | phosphatases | phosphoinositide 3-kinase | PH domain leucine-rich repeat protein phosphatase | HOMEOSTASIS | PROTEIN | KINASE | PROMOTER MUTATIONS | RILEY-RUVALCABA-SYNDROME | IMMUNOLOGY | ALLERGY | RESOLUTION MELTING ANALYSIS | AKT-MTOR | LYMPHOID HYPERPLASIA | EXPRESSION | Autoimmunity | Humans | Hyperplasia | Middle Aged | Phosphoprotein Phosphatases - metabolism | Male | Immunological Synapses - metabolism | Young Adult | Forkhead Transcription Factors - metabolism | Membrane Potential, Mitochondrial | Adult | Child | Hamartoma Syndrome, Multiple - immunology | Lymphocyte Subsets - physiology | T-Lymphocytes, Regulatory - physiology | PTEN Phosphohydrolase - genetics | Hamartoma Syndrome, Multiple - genetics | Signal Transduction | Cells, Cultured | B-Lymphocytes - physiology | PTEN Phosphohydrolase - metabolism | Nuclear Proteins - metabolism | Mutation - genetics | Protein Transport | Adolescent | Protein Binding | Aged | Medical colleges | Care and treatment | Phosphatases | Gene mutations | Analysis | Children's hospitals | Genomics | Medical genetics | Genetic research | T cells | Tumors | Hamartoma | Proteins | Blood & organ donations | Hematology | Biopsy | Lymphocytes | T cell receptors | Mutation | Kinases | Metabolism | Phosphatase | FACS, Fluorescence-activated cell sorting | TCR, T-cell receptor | mTOR complex 1 | NHERF1, Na+ | H+-exchanger 3 regulatory factor | MALT, Mucosa-associated lymphoid tissue | APC, Allophycocyanin | SHIP, Src homology domain 2–containing inositol phosphatase | HRM, High Resolution DNA Melting | FITC, Fluorescein isothiocyanate | PP2A, Protein phosphatase 2A | mTORC1, PTEN | PHTS, PTEN hamartoma tumor syndrome | PerCP, Peridinin-chlorophyll-protein complex | CS, Cowden syndrome | POD, Peroxidase | Tmem, Memory T | TMRE, Tetramethylrhodamine-ethylester | Immune Deficiencies, Infection, and Systemic Immune Disorders | IC50, Inhibitory concentration of 50 | CTLA-4, Cytotoxic T lymphocyte–associated antigen 4 | PHLPP, PH domain leucine-rich repeat protein phosphatase | AKT | DLG1, Scaffold protein discs, large homolog 1 | FOXP3, Forkhead box P3 | ICAM-1, Intercellular adhesion molecule 1 | iTreg, In vitro induced regulatory T | PE, Phycoerythrin | PI3K, Phosphoinositide 3-kinase | mTOR, Mammalian target of rapamycin | PTEN, Phosphatase and tensin homologue deleted on chromosome 10
Journal Article
Disease models & mechanisms, ISSN 1754-8403, 05/2018, Volume 11, Issue 5, p. dmm031005
PTEN hamartoma tumour syndrome (PHTS) is a heterogeneous group of rare, autosomal dominant disorders associated with PTEN germline mutations. PHTS patients... 
Pten phosphatase | Retinal malformation | Non-cell autonomy | PHTS | Drug therapy | Hamartoma | RAPAMYCIN TREATMENT | GERMLINE PTEN | SUPPRESSOR PTEN | PATHOLOGY | TSC2 MUTATION | MTOR | CELL BIOLOGY | COWDEN-LIKE SYNDROME | TUBEROUS SCLEROSIS COMPLEX | NEGATIVE REGULATION | EMBRYONIC LETHALITY | MICE
Journal Article
CANCERS, ISSN 2072-6694, 06/2019, Volume 11, Issue 7, p. 975
PTEN hamartoma tumor syndrome (PHTS) encompasses different syndromic disorders which are associated with autosomal-dominant mutations of the tumor suppressor... 
COWDEN-SYNDROME | RISKS | PHTS | ONCOLOGY | children | ADOLESCENTS | PTEN | head circumference | MUTATIONS | SPECTRUM | CANCER | CHILDHOOD
Journal Article
Journal Article
Computational and Structural Biotechnology Journal, ISSN 2001-0370, 2019, Volume 17, pp. 737 - 745
Health span is driven by a precise interplay between genes and the environment. Cell response to environmental cues is mediated by signaling cascades and... 
Chromatin hub | Aging | Longevity | SNP | FOXO3
Journal Article
Endocrine Pathology, ISSN 1046-3976, 12/2010, Volume 21, Issue 4, pp. 219 - 226
Journal Article
Cancer Research, ISSN 0008-5472, 05/2013, Volume 73, Issue 10, pp. 3029 - 3040
Journal Article