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1. Full Text A tomato B‐box protein SlBBX20 modulates carotenoid biosynthesis by directly activating PHYTOENE SYNTHASE 1, and is targeted for 26S proteasome‐mediated degradation
by Xiong, Cheng and Luo, Dan and Lin, Aihua and Zhang, Chunli and Shan, Libo and He, Ping and Li, Bo and Zhang, Qiaomei and Hua, Bin and Yuan, Zilv and Li, Hanxia and Zhang, Junhong and Yang, Changxian and Lu, Yongen and Ye, Zhibiao and Wang, Taotao
New Phytologist, ISSN 0028-646X, 01/2019, Volume 221, Issue 1, pp. 279 - 294
Carotenoids play important roles in many biological processes, such as light harvesting, photoprotection and visual attraction in plants. However, the... 
CUL4‐DDB1‐DET1 complex | carotenoid | tomato | Solanum lycopersicum | PSY1 | BBX20 | tomato (Solanum lycopersicum) | SlBBX20 | CUL4-DDB1-DET1 complex | MANIPULATION | SALT TOLERANCE | PLANT SCIENCES | PHYTOENE SYNTHASE GENE | FRUIT | REPRESSION | ARABIDOPSIS | ACCUMULATION | TRANSCRIPTION FACTOR | EXPRESSION | PHYTOCHROME | Ubiquitin | Chlorophyll | Ligases | Analysis | Physiological aspects | Phylogeny | Tomatoes | Plants (botany) | Stability | Transcription | Protein biosynthesis | Biosynthesis | Zinc | Biological activity | Substrates | Fruits | Degradation | Proteins | Leaves | Ubiquitination | Carotenoids | Phytoene synthase | Interactions | Ubiquitin-protein ligase
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2. Full Text The expression of 1-deoxy- d-xylulose synthase and geraniol-10-hydroxylase or anthranilate synthase increases terpenoid indole alkaloid accumulation in Catharanthus roseus hairy roots
by Peebles, Christie A.M and Sander, Guy W and Hughes, Erik H and Peacock, Ryan and Shanks, Jacqueline V and San, Ka-Yiu
Metabolic Engineering, ISSN 1096-7176, 2011, Volume 13, Issue 2, pp. 234 - 240
The terpenoid indole alkaloid (TIA) pathway in produces two important anticancer drugs, vinblastine and vincristine, in very low yields. This study focuses on... 
Plant metabolic engineering | Tissue culture | Methyl-erythritol phosphate pathway | Terpenoid indole alkaloid | Madagascar periwinkle | CELL-SUSPENSION CULTURES | SECONDARY METABOLISM | ALPHA-SUBUNIT | GERANIOL 10-HYDROXYLASE | STRICTOSIDINE SYNTHASE | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOSYNTHESIS | 5-PHOSPHATE SYNTHASE | PHYTOENE SYNTHASE | TRYPTOPHAN DECARBOXYLASE | Anthranilate Synthase - biosynthesis | Plant Roots - metabolism | Cells, Cultured | Plant Roots - genetics | Transferases - biosynthesis | Secologanin Tryptamine Alkaloids - metabolism | Transferases - genetics | Catharanthus - metabolism | Plants, Genetically Modified - metabolism | Anthranilate Synthase - genetics | Plant Roots - chemistry | Gene Expression Regulation, Plant | Cytochrome P-450 Enzyme System - biosynthesis | Cytochrome P-450 Enzyme System - genetics | Vinblastine - biosynthesis | Catharanthus - genetics | Vincristine - biosynthesis | Phosphates | Alkaloids | Metabolites | Genetic research | Tryptophan | Sugars | Monosaccharides
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3. Full Text Identification and functional analysis of the geranylgeranyl pyrophosphate synthase gene (crtE) and phytoene synthase gene (crtB) for carotenoid biosynthesis in Euglena gracilis
by Kato, Shota and Takaichi, Shinichi and Ishikawa, Takahiro and Asahina, Masashi and Takahashi, Senji and Shinomura, Tomoko
BMC Plant Biology, ISSN 1471-2229, 01/2016, Volume 16, Issue 1, p. 4
Euglena gracilis, a unicellular phytoflagellate within Euglenida, has attracted much attention as a potential feedstock for renewable energy production. In... 
CrtE | Geranylgeranyl pyrophosphate synthase | Euglena gracilis | Light stress | Phytoene synthase | Carotenoid biosynthesis | CrtB | Amino Acid Sequence | Sequence Alignment | Euglena gracilis - enzymology | Euglena gracilis - genetics | Genes, Plant | Light | Cloning, Molecular | Molecular Sequence Data | Geranylgeranyl-Diphosphate Geranylgeranyltransferase - genetics | Carotenoids - biosynthesis | Euglena gracilis - metabolism | Euglena | Physiological aspects | Genetic aspects | Carotenoids | Research
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4. Full Text The Phytoene synthase gene family of apple (Malus x domestica) and its role in controlling fruit carotenoid content
by Ampomah-Dwamena, Charles and Driedonks, Nicky and Lewis, David and Shumskaya, Maria and Chen, Xiuyin and Wurtzel, Eleanore T and Espley, Richard V and Allan, Andrew C
BMC Plant Biology, ISSN 1471-2229, 07/2015, Volume 15, Issue 1, p. 185
Background: Carotenoid compounds play essential roles in plants such as protecting the photosynthetic apparatus and in hormone signalling. Coloured carotenoids... 
Promoter | Apple | Carotenoids | Fruit flesh | Phytoene | Phytoene synthase | Fruit skin | Transient activation | GATEWAY BINARY VECTORS | TRANSCRIPTION FACTORS | BIOSYNTHETIC-PATHWAY | SKIN COLOR | BETA | PLANT SCIENCES | FUNCTIONAL-ANALYSIS | ACCUMULATION | ARABIDOPSIS | LYCOPENE CYCLASE | TOMATO | Amino Acid Sequence | Plant Proteins - genetics | Sequence Alignment | Malus - metabolism | Carotenoids - metabolism | Gene Expression Regulation, Plant | Plant Proteins - metabolism | Phylogeny | Fruit - metabolism | Geranylgeranyl-Diphosphate Geranylgeranyltransferase - genetics | Geranylgeranyl-Diphosphate Geranylgeranyltransferase - metabolism | Malus - genetics | Skin | DNA binding proteins | Genetic transcription | Genetic translation
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5. Full Text Plasmodium falciparum parasites overexpressing farnesyl diphosphate synthase/geranylgeranyl diphosphate synthase are more resistant to risedronate
by Gabriel, Heloisa B and Azevedo, Mauro F and Kimura, Emília A and Katzin, Alejandro M
Memorias do Instituto Oswaldo Cruz, ISSN 0074-0276, 2018, Volume 113, Issue 10, p. e180174
Farnesyl diphosphate synthase/geranylgeranyl diphosphate synthase (FPPS/GGPPS) is a key enzyme in the synthesis of isoprenic chains. Risedronate, a... 
INTRAERYTHROCYTIC STAGES | FPPS/GGPPS | MALARIA PARASITES | risedronate | TROPICAL MEDICINE | CAROTENOID BIOSYNTHESIS | BISPHOSPHONATES | ENZYME | overexpression | PATHWAY | P. falciparum | ANTIMALARIAL ACTIVITY | RED-BLOOD-CELLS | EXPRESSION | PHYTOENE SYNTHASE | PARASITOLOGY | Plasmodium falciparum - enzymology | Reference Values | Plasmodium falciparum - drug effects | Blotting, Western | Antimalarials - pharmacology | Antimalarials - analysis | Risedronate Sodium - analysis | Animals | Analysis of Variance | Risedronate Sodium - pharmacology | Farnesyltranstransferase - biosynthesis | Plasmodium falciparum - growth & development | Drug Resistance | Farnesyltranstransferase - analysis
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6. Full Text Arabidopsis OR proteins are the major posttranscriptional regulators of phytoene synthase in controlling carotenoid biosynthesis
by Xiangjun Zhou and Ralf Welsch and Yong Yang and Daniel Álvarez and Matthias Riediger and Hui Yuan and Tara Fish and Jiping Liu and Theodore W. Thannhauser and Li Li
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 03/2015, Volume 112, Issue 11, pp. 3558 - 3563
Carotenoids are indispensable natural pigments to plants and humans. Phytoene synthase (PSY), the rate-limiting enzyme in the carotenoid biosynthetic pathway,... 
Posttranscriptional regulation | Arabidopsis | Carotenoid | Phytoene synthase | OR | MULTIDISCIPLINARY SCIENCES | POTATO-TUBERS | carotenoid | phytoene synthase | CAULIFLOWER | posttranscriptional regulation | BETA-CAROTENE | ORANGE GENE | RIPENING PROCESSES | ACCUMULATION | PARTIAL-PURIFICATION | STRESS TOLERANCE | EXPRESSION | TOMATO | Arabidopsis - enzymology | Immunoprecipitation | Protein Multimerization | Structure-Activity Relationship | Gene Knockout Techniques | Carotenoids - biosynthesis | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Arabidopsis Proteins - chemistry | Mass Spectrometry | Gene Expression Regulation, Plant | Protein Binding | Plastids - metabolism | Geranylgeranyl-Diphosphate Geranylgeranyltransferase - genetics | Physiological aspects | Plant cellular control mechanisms | Genetic aspects | Carotenoids | Gene expression | Biological Sciences
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7. Full Text The role of 1-deoxy-d-xylulose-5-phosphate synthase and phytoene synthase gene family in citrus carotenoid accumulation
by Peng, Gang and Wang, Chunyan and Song, Song and Fu, Xiumin and Azam, Muhammad and Grierson, Don and Xu, Changjie
Plant Physiology and Biochemistry, ISSN 0981-9428, 10/2013, Volume 71, pp. 67 - 76
Three 1-deoxy- -xylulose-5-phosphate synthases (DXS) and three phytoene synthases (PSY) were identified in citrus, from Affymetrix GeneChip Citrus Genome... 
Citrus | Chromoplast | 1-Deoxy-d-xylulose 5-phosphate | Carotenoid | Phytoene synthase | MUTANT | LOCALIZATION | SINENSIS L. OSBECK | FRUIT-DEVELOPMENT | IDENTIFICATION | PLANT SCIENCES | ENZYME | ISOPRENOID BIOSYNTHESIS | PATHWAY | 1-Deoxy-D-xylulose 5-phosphate | EXPRESSION | TOMATO | Transferases - metabolism | Citrus - metabolism | Geranylgeranyl-Diphosphate Geranylgeranyltransferase - metabolism | Carotenoids - metabolism | Citrus - enzymology | Citrus fruits | Phosphates | Genes | Genomics | Physiological aspects | Sugars | Monosaccharides
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8. Full Text Arabidopsis GERANYLGERANYL DIPHOSPHATE SYNTHASE 11 is a hub isozyme required for the production of most photosynthesis‐related isoprenoids
by Ruiz‐Sola, M. Águila and Coman, Diana and Beck, Gilles and Barja, M. Victoria and Colinas, Maite and Graf, Alexander and Welsch, Ralf and Rütimann, Philipp and Bühlmann, Peter and Bigler, Laurent and Gruissem, Wilhelm and Rodríguez‐Concepción, Manuel and Vranová, Eva
New Phytologist, ISSN 0028-646X, 01/2016, Volume 209, Issue 1, pp. 252 - 264
Most plastid isoprenoids, including photosynthesis‐related metabolites such as carotenoids and the side chain of chlorophylls, tocopherols (vitamin E),... 
Arabidopsis thaliana | gene paralogues | GGPPS | geranylgeranyl diphosphate synthase | Gene paralogues | Geranylgeranyl diphosphate synthase | GGPPS11 | SIDE-CHAIN | BIMOLECULAR FLUORESCENCE COMPLEMENTATION | PLANT ISOPRENOIDS | PLANT SCIENCES | CAROTENOID BIOSYNTHESIS | NETWORK ANALYSIS | PROTEIN INTERACTIONS | THALIANA | GENE FAMILY | PARTIAL-PURIFICATION | PHYTOENE SYNTHASE | Arabidopsis Proteins - genetics | Arabidopsis - enzymology | Isoenzymes | Alkyl and Aryl Transferases - metabolism | Chlorophyll - metabolism | Polyisoprenyl Phosphates - metabolism | Protein Interaction Mapping | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Plastids - enzymology | Phenotype | Terpenes - metabolism | Alkyl and Aryl Transferases - genetics | Carotenoids - metabolism | Photosynthesis | Metabolites | Analysis | Phytochemistry | Physiological aspects | Tocopherols | Protein-protein interactions
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9. Full Text Phytoene synthase genes in tomato (Solanumlycopersicum L.) – new data on the structures, the deduced amino acid sequences and the expression patterns
by Giorio, Giovanni and Stigliani, Adriana Lucia and D’Ambrosio, Caterina
FEBS Journal, ISSN 1742-464X, 02/2008, Volume 275, Issue 3, pp. 527 - 535
The fruit of tomato ( Solanum lycopersicum  L.) is a berry: red, fleshy and rich in seeds. Its colour is due to the high content of lycopene whose synthesis is... 
fruit colour | chromoplast | chloroplast | carotenoid metabolism | phytoene synthase | Chromoplast | Fruit colour | Chloroplast | Phytoene synthase | Carotenoid metabolism | ENCODES | SOLANACEAE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CAROTENOID BIOSYNTHESIS PATHWAY | NARCISSUS-PSEUDONARCISSUS | EVOLUTION | FRUIT | CLONING | ENZYMES | DUPLICATION | CHROMOPLASTS | Amino Acid Sequence | Lycopersicon esculentum - metabolism | Isoenzymes - genetics | Alkyl and Aryl Transferases - metabolism | DNA, Complementary - genetics | Molecular Sequence Data | Lycopersicon esculentum - enzymology | Fruit - enzymology | Reverse Transcriptase Polymerase Chain Reaction | Sequence Analysis, DNA | Gene Expression Regulation, Enzymologic | Sequence Homology, Amino Acid | Plant Proteins - genetics | Alkyl and Aryl Transferases - genetics | Isoenzymes - metabolism | Carotenoids - metabolism | Gene Expression Regulation, Plant | Geranylgeranyl-Diphosphate Geranylgeranyltransferase | Lycopersicon esculentum - genetics | Plant Proteins - metabolism | DNA, Complementary - chemistry | Fruit - metabolism | Fruit - genetics | Polymerase chain reaction | Physiological aspects | Genetic research | Analysis | Lycopene | Proteins | Enzymes | Biochemistry | Vegetables | Genomics | Botany
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10. Full Text Transcripts levels of Phytoene synthase 1 (Psy-1) are associated to semolina yellowness variation in durum wheat (Triticum turgidum L. ssp. durum)
by Vargas, Víctor Hugo and Schulthess, Albert and Royo, Conxita and Matus, Iván and Schwember, Andrés R
Journal of Cereal Science, ISSN 0733-5210, 03/2016, Volume 68, pp. 155 - 163
( ) is an essential synthesis gene influencing semolina yellowness while catalase ( ) is a catabolic enzyme that causes color loss. The main objective of this... 
Phytoene synthase 1 | Durum wheat | Semolina yellowness | Real time q-PCR | ACTIVATION | FOOD SCIENCE & TECHNOLOGY | VALIDATION | COMPONENTS | VAR. DURUM | IDENTIFICATION | PIGMENT CONTENT | GENE | ENDOSPERM | GRAIN | COLOR | Genetic research | Enzymes | Wheat | Genes | Plant genetics
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11. Full Text Epistasis in tomato color mutations involves regulation of phytoene synthase 1 expression by cis-carotenoids
by David E. Kachanovsky and Shdema Filler and Tal Isaacson and Joseph Hirschberg
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2012, Volume 109, Issue 46, pp. 19021 - 19026
Tomato (Solanum lycopersicum) fruit accumulate the red carotenoid pigment Iycopene. The recessive mutation yellow-flesh (locus r) in tomato eliminates fruit... 
Enzymes | Phenotypes | Carotenoids | Genes | Alleles | Biosynthesis | Epistasis | Gene expression regulation | Plants | Genetic mutation | Fruit development | Tomato breeding | fruit development | ARABIDOPSIS-THALIANA | MULTIDISCIPLINARY SCIENCES | tomato breeding | TANGERINE | BETA-CAROTENE | LYCOPENE | PHYTOENE SYNTHASE GENES | FRUIT | PATHWAY | BIOSYNTHESIS | ISOMERASE | PLANTS | Pigmentation - physiology | Lycopersicon esculentum - enzymology | Gene Expression Regulation, Enzymologic - physiology | Genes, Recessive | Alkyl and Aryl Transferases - biosynthesis | Plant Proteins - genetics | Epistasis, Genetic - physiology | Alkyl and Aryl Transferases - genetics | Gene Expression Regulation, Plant - physiology | Carotenoids - metabolism | Geranylgeranyl-Diphosphate Geranylgeranyltransferase | Lycopersicon esculentum - genetics | Mutation | Plant Proteins - biosynthesis | Carotenoids - genetics | Gene mutations | Plant genetics | Physiological aspects | Genetic aspects | Tomatoes | Research | Gene expression | Health aspects | Genetic epistasis | Biological Sciences
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12. Full Text Cloning and expression analysis of the phytoene synthase gene in 'Granny Smith' apple (Malus × domestica Borkh.)
by Zhang, Xiao-Jun and Gao, Yan and Wen, Peng-Fei and Hao, Yan-Yan and Chen, Xue-Xiong
Biotechnology & Biotechnological Equipment, ISSN 1310-2818, 09/2018, Volume 32, Issue 5, pp. 1105 - 1112
Phytoene synthase (PSY) plays a key role in the biosynthesis and accumulation of carotenoids as the first rate-limiting enzyme in the plant carotenoid pathway.... 
'Granny Smith' apple | phytoene synthase | cloning | gene expression | ‘Granny Smith’ apple | CAROTENOID BIOSYNTHESIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | COLOR | ACCUMULATION | Proteins | Biosynthesis | Carotenoids | Gene expression | Cloning
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13. Full Text Characterization and expression analysis of phytoene synthase from bread wheat (Triticum aestivum L.)
by Flowerika, Flowerika and Alok, Anshu and Kumar, Jitesh and Thakur, Neha and Pandey, Ashutosh and Pandey, Ajay Kumar and Upadhyay, Santosh Kumar and Tiwari, Siddharth
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0162443
Phytoene synthase (PSY) regulates the first committed step of the carotenoid biosynthetic pathway in plants. The present work reports identification and... 
LIGHT-DEPENDENT REGULATION | LYCOPENE | CAROTENOGENESIS | EVOLUTION | CAROTENOID BIOSYNTHETIC-PATHWAY | ENZYMES | PROVITAMIN | MULTIDISCIPLINARY SCIENCES | GENE FAMILY | ARABIDOPSIS | CDNA CLONING | Triticum - genetics | Gene Expression | Genes, Plant - genetics | Triticum - growth & development | Geranylgeranyl-Diphosphate Geranylgeranyltransferase - physiology | Phylogeny | Triticum - enzymology | Genes, Plant - physiology | Geranylgeranyl-Diphosphate Geranylgeranyltransferase - genetics | Geranylgeranyl-Diphosphate Geranylgeranyltransferase - metabolism | Real-Time Polymerase Chain Reaction | beta Carotene - metabolism | Proteins | Cladistic analysis | Analysis | Genes | Wheat industry | Wheat | Beta carotene | Cereal crops | Biotechnology | Enzyme activity | Genomics | Biological evolution | Science | Biosynthesis | Genomes | Regulatory sequences | Tissues | Data bases | Bread | Conserved sequence | Carotenoids | Developmental stages | Enzymatic activity | Phytoene synthase | Bacteria | Complementation | Drought | Localization | Food | Stresses | Enzymes | Plants (botany) | Abiotic stress | Amino acid sequence | Corn | Stress | β-Carotene
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14. Full Text Involvement of multiple phytoene synthase genes in tissue-and cultivar-specific accumulation of carotenoids in loquat
by Fu, Xiumin and Feng, Chao and Wang, Chunyan and Yin, Xueren and Lu, Pengjun and Grierson, Don and Xu, Changjie and Chen, Kunsong
Journal of Experimental Botany, ISSN 0022-0957, 2014, Volume 65, Issue 16, pp. 4679 - 4689
Differences in carotenoid accumulation between tissues and cultivars is common in plants. White-fleshed loquat cultivars had low levels of carotenoids in the... 
loquat (Eriobotrya japonica) | mutation | tissue-specific expression | phytoene synthase | Carotenoid | function | TOMATO FRUIT | CITRUS | MECHANISMS | BETA | PLANT SCIENCES | RED | PATHWAY | BIOSYNTHESIS | PLANTS | ZEAXANTHIN | COLOR MUTATIONS | Genes, Plant | RNA, Messenger - genetics | Phylogeny | RNA, Messenger - metabolism | Reve