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pi, propidium iodide (161) 161
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Redox Biology, ISSN 2213-2317, 04/2019, Volume 22, p. 101157
Ultraviolet B (UVB) irradiation can induce reactive oxygen species (ROS) production and apoptosis in human lens epithelial cells (HLECs), thus leading to the... 
UVB | TRIM69 | Foxo3a | Cataract | p53 | OXIDATIVE STRESS | INDUCED-APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | CELL APOPTOSIS | FAMILY | IRRADIATION | ULTRAVIOLET-RADIATION | LENS | EXPRESSION | E3 UBIQUITIN LIGASE
Journal Article
Redox Biology, ISSN 2213-2317, 01/2019, Volume 20, pp. 367 - 378
Manganese(III) porphyrins (MnPs) are superoxide dismutase (SOD) mimics with demonstrated beneficial effects in cancer treatment in combination with chemo- and... 
SOD mimics | Manganese porphyrins | Redox modulation | Cell invasion | Cell migration | Cancer | MN PORPHYRINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INVASION | EPITHELIAL-CELLS | PROTECTIVE ROLE | HYDROGEN-PEROXIDE | NF-KAPPA-B | SUPEROXIDE-DISMUTASE | UP-REGULATION | OXIDATIVE INJURY
Journal Article
Biochemical Journal, ISSN 0264-6021, 05/2015, Volume 467, Issue 3, pp. 473 - 486
Acid ecto-phosphatase activity has been implicated in Leishmania donovani promastigote virulence. In the present study, we report data contributing to the... 
Histidine acid phosphatase | Ecto-enzyme | Leishmania virulence | TRYPANOSOMA-RANGELI | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | CRYSTAL-STRUCTURES | MECHANISMS | ecto-enzyme | ENDOCYTOSIS | GENOME | SURFACE-MEMBRANE | REDOX REGULATION | histidine acid phosphatase | PARASITE | PROTEINS | Species Specificity | Humans | Virulence | Molecular Sequence Data | Genes, Protozoan | Phylogeny | Protozoan Proteins - genetics | Recombinant Fusion Proteins - metabolism | Macrophages - parasitology | Acid Phosphatase - metabolism | Leishmania - enzymology | Protozoan Proteins - metabolism | Conserved Sequence | Protozoan Proteins - chemistry | Cell Line | Leishmania donovani - enzymology | Leishmania donovani - pathogenicity | Models, Molecular | Recombinant Fusion Proteins - chemistry | Animals | Acid Phosphatase - chemistry | Recombinant Fusion Proteins - genetics | Leishmania donovani - genetics | Mice | HeLa Cells | Leishmania - pathogenicity | Acid Phosphatase - genetics | Leishmania - genetics | LdSAcP, Leishmania donovani secreted acid phosphatase | pNPP, p-nitrophenyl phosphate | Ab, antibody | BW, black and white | mAb, monoclonal antibody | pNP, p-nitrophenolate | Ct, cycle threshold value | HAcP, histidine acid phosphatase | pAb, polyclonal antibody | mRFP, monomeric RFP | EMBL, European Molecular Biology Laboratory | wt, wild type | LdMAcP, Leishmania donovani membrane acid phosphatase | RPMI, Roswell Park Memorial Institute medium | qPCR, quantitative PCR | BLAST, Basic Local Alignment Search Tool | RT, room temperature | SP, signal peptide | TM, transmembrane | PI, propidium iodide | hiFBS, heat-inactivated FBS | ORF, open reading frame | FL, fluorescence | Pi, inorganic phosphate | EndoF, endoglycosidase F | hPAP, human prostatic acid phosphatase | aa, amino acids | FP, flagellar pocket | IF, immunofluorescence | ER, endoplasmic reticulum
Journal Article
Toxicology Reports, ISSN 2214-7500, 2015, Volume 2, Issue C, pp. 624 - 637
Effects of triclosan (5-chloro-2′-(2,4-dichlorophenoxy)phenol) on mammalian cells were investigated using human peripheral blood mono nuclear cells (PBMC),... 
Glycolysis | Electric transmembrane potential | Sperm motility | Uncoupler | Oxidative phosphorylation | Acidosis
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 06/2016, Volume 33, pp. 88 - 98
The effects of an equimolar mixture of -arginine and -glutamate (Arg·Glu) on cell viability and cellular stress using in vitro cell culture systems are... 
Excipient | Membrane markers | Inflammation | Monoclonal antibody | Arginine glutamate | Apoptosis | Cell Line | Cell Survival - drug effects | Sodium Chloride - pharmacology | Dipeptides - pharmacology | Humans | Osmolar Concentration | Fibroblasts - drug effects | Drug Compounding | Excipients - pharmacology | Interleukin-8 - metabolism | Proteins - chemistry | Nitric Oxide - metabolism | Fibroblasts - metabolism | Monoclonal antibodies | Arginine | Glutamate | Cell death | Analysis | Index Medicus | APC, allophycocyanin | DC, dendritic cell | EDTA, ethylenediaminetetraacetic acid | Arg·HCl, arginine hydrochloride | IC50, the concentration | Arg·Glu, arginine glutamate | MFI, mean fluorescence intensity | ICAM-1, intercellular adhesion molecule 1 | ANOVA, one-way analysis of variance | TLR, toll-like receptor | osmolality required to cause a 50% loss in viability | NaGlu, sodium glutamate | BSA, bovine serum albumin | PI, propidium iodide | TNF, tumor necrosis factor | ELISA, enzyme-linked immunosorbant assay | FITC, fluorescein isothiocyanate | FSC-H, forward scatter | PBS, phosphate buffered saline | FDA, Food and Drug Administration | 7-AAD, 7-aminoactinomycin D | SSC-H, side scatter | IL, interleukin | LPS, lipopolysaccharide | GRAS, Generally Recognized as Safe | HLA-DR, human leukocyte antigen | FCS, fetal calf serum
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 01/2018, Volume 8, Issue 1, pp. 85 - 96
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 03/2019, Volume 9, Issue 2, pp. 279 - 293
Over recent decades, many studies have reported that hypocrellin A (HA) can eliminate cancer cells with proper irradiation in several cancer cell lines.... 
iTRAQ | Reactive oxygen species | Photodynamic therapy | Hypocrellin A | LC–MS/MS | Proteomic | OXIDATIVE STRESS | MECHANISMS | DEATH | LC-MS/MS | NANOPARTICLES | IN-VITRO | THERAPY | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | Dox, doxorubicin | OCR, oxygen consumption rate | IAA, iodoacetamide | z-IETD-fmk, z-Ile-Glu-Asp-fluoromethylketone | FCCP, carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone | PS, photosensitizer | ACN, acetonitrile | HRP, horseradish peroxidase | iTRAQ, isobaric tag for relative and absolute quantitation | DCFH-DA, 2′,7′-dichlorofuorescin diacetate | DMEM, Dulbecco׳s modified Eagle׳s medium | MPT, mitochondrial permeability transition | SCX, strong cation exchange | PDT, photodynamic therapy | ROS, reactive oxygen species | NAC, N-acetyl-l-cysteine | IKK, IκB kinase complex | MMP, mitochondrial membrane potential | CLSM, confocal laser scanning confocal microscopy | GO, gene ontology | PI, propidium iodide | HA, hypocrellin A | LC–MS | TCM, traditional Chinese medicinal | JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl-benzimidazolcarbocyanine iodide | UA, urea | ECL, enhanced chemiluminescence | z-VAD-fmk, z-Val-Ala-Asp-fluoromethylketone | FDR, false discovery rate | TEM, transmission electron microscope | Original article | TFA, trifluoroacetic acid | z-LEHD-fmk, z-Leu-Glu(OMe)-His-Asp(OMe)-fluoromethylketone
Journal Article
EBioMedicine, ISSN 2352-3964, 07/2016, Volume 9, Issue C, pp. 61 - 76
PPARγ has emerged as a master regulator of macrophage polarization and is the molecular target of the thiazolidinedione drugs. Here we show that apigenin binds... 
NF-κB | Macrophage polarization | Apigenin | Obesity-related inflammation | PPARγ | MEDICINE, RESEARCH & EXPERIMENTAL | INDUCIBLE CYCLOOXYGENASE | P65 PHOSPHORYLATION | METABOLIC SYNDROME | RECEPTOR-GAMMA | NITRIC-OXIDE SYNTHASE | PPAR gamma | NF-kappa B | ANTIINFLAMMATORY PROPERTIES | INSULIN-RESISTANCE | MOUSE MACROPHAGES | NF-KAPPA-B | ALTERNATIVE ACTIVATION | Inflammation - pathology | Obesity - immunology | Male | Metabolic Syndrome - metabolism | NF-kappa B - metabolism | PPAR gamma - metabolism | Apigenin - chemistry | Adipose Tissue - metabolism | Inflammation - complications | Inflammation - metabolism | Metabolic Syndrome - immunology | Protein Interaction Domains and Motifs | Thiazolidinediones - pharmacology | Macrophages, Peritoneal - drug effects | Macrophages - immunology | Disease Models, Animal | Cell Line | Cytokines - metabolism | Signal Transduction | Macrophage Activation - immunology | Obesity - complications | Macrophages, Peritoneal - immunology | Immunophenotyping | Inflammation - immunology | Obesity - metabolism | Obesity - pathology | Macrophages - metabolism | Phenotype | Animals | PPAR gamma - agonists | Biomarkers | Protein Binding | Macrophages - drug effects | Mice | Macrophage Activation - drug effects | Macrophages, Peritoneal - metabolism | Apigenin - pharmacology | PPAR gamma - chemistry
Journal Article
FEBS Letters, ISSN 0014-5793, 12/2006, Volume 580, Issue 30, pp. 6880 - 6884
Journal Article