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article (2) 2
biochemistry & molecular biology (2) 2
humans (2) 2
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papillary carcinomas (2) 2
pi3k (2) 2
ras (2) 2
abl, abelson leukemia proto-oncogene (1) 1
activated protein-kinase (1) 1
activating mutations (1) 1
activation (1) 1
adap, adhesion and degranulation promoting adapter protein (1) 1
akt (1) 1
animals (1) 1
asc, apoptosis-associated speck-like protein containing a card (1) 1
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beta-gamma-subunits (1) 1
biosensing techniques - methods (1) 1
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braf (1) 1
braf mutations (1) 1
braf v600e mutation (1) 1
c3g, crk sh3 domain-binding guanine nucleotide exchange factor (1) 1
ca2+ indicators (1) 1
caldag-gefi, calcium and dag-regulated guanine nucleotide exchange factor i (1) 1
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differentiated thyroid cancer (1) 1
disc, death-inducing signaling complex (1) 1
dynamic-range (1) 1
endocytosis (1) 1
endothelial growth-factor (1) 1
energy-transfer (1) 1
epac1, exchange protein activated by cyclic amp 1 (1) 1
epigenetic alteration (1) 1
erk, extracellular signal-regulated kinase (1) 1
erm, ezrin-radixin-moesin (1) 1
esl-1, e-selectin ligand 1 (1) 1
extracellular signal-regulated map kinases - genetics (1) 1
extracellular signal-regulated map kinases - physiology (1) 1
fadd, fas-associated protein with death domain (1) 1
fc receptors (1) 1
fcr, fc-receptor (1) 1
fcrγ, fc-receptor γ-chain (1) 1
fgr, gardner–rasheed feline sarcoma proto-oncogene (1) 1
fluorescent protein (1) 1
fmlp, formly-met-leu-phe (1) 1
follicular variant (1) 1
fret (1) 1
g-csf, granulocyte colony-stimulating factor (1) 1
gap, gtpase activating protein (1) 1
gene amplification (1) 1
gene expression regulation, neoplastic - physiology (1) 1
gene-expression profiles (1) 1
genetics & heredity (1) 1
gm-csf, granulocyte (1) 1
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gpcr, g protein-coupled receptor (1) 1
gpi, glycosylphosphatidylinositol anchor (1) 1
green (1) 1
grk, gpcr kinase (1) 1
hck, hematopoietic cell kinase (1) 1
high prevalence (1) 1
high-affinity receptor (1) 1
histone deacetylase inhibitor (1) 1
human polymorphonuclear leukocytes (1) 1
icam-1, intercellular adhesion molecule 1 (1) 1
ifn, interferon (1) 1
ikk, iκb kinase (1) 1
il, interleukin (1) 1
immunology (1) 1
immunology and allergy (1) 1
in-vivo (1) 1
inflammation (1) 1
integrins (1) 1
ip3, inositol-tris-phosphate (1) 1
irak, il-1 receptor-associated kinase (1) 1
irf, ifn regulatory factor (1) 1
itam, immunoreceptor tyrosine-based activation motif (1) 1
iκb, inhibitor of nf-κb (1) 1
jak, janus kinase (1) 1
jnk, c-jun n-terminal kinase (1) 1
kinases (1) 1
lad, leukocyte adhesion deficiency (1) 1
lectins (1) 1
leukocyte adhesion deficiency (1) 1
lfa-1, lymphocyte function-associated receptor 1 (1) 1
ltb4, leukotriene b4 (1) 1
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1. Full Text Neutrophil cell surface receptors and their intracellular signal transduction pathways
by Futosi, Krisztina and Fodor, Szabina and Mócsai, Attila
International Immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but their inappropriate activation also contributes to tissue... 
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | HIGH-AFFINITY RECEPTOR | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | BETA-GAMMA-SUBUNITS | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
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2. A minireview: The role of MAPK/ERK and PI3K/Akt pathways in thyroid follicular cell-derived neoplasm
by Brzezianska, Ewa and Pastuszak-Lewandoska, Dorota
Frontiers in Bioscience, ISSN 1093-9946, 01/2011, Volume 16, Issue 2, pp. 422 - 439
The MAPK/ERK (mitogen - activated protein kinase/extracellular signal-regulated kinase signaling pathway) and PI3K/Akt (lipid kinase phoshoinositide-3-kinase... 
Signaling pathways | Gene amplification | MAPK/ERK | Activating mutations | Thyroid Carcinoma | Review | Epigenetic alteration | PI3K/Akt | PHOSPHATIDYLINOSITOL 3-KINASE/AKT | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION PROFILES | Activating Mutations | PAPILLARY CARCINOMAS | CELL BIOLOGY | Gene Amplification | RAS ONCOGENE MUTATIONS | PIK3CA GENE | Signaling Pathways | SIGNALING PATHWAY | BRAF MUTATIONS | Epigenetic Alteration | RET/PTC REARRANGEMENTS | thyroid Carcinoma | POORLY DIFFERENTIATED CARCINOMAS | HIGH PREVALENCE | PTEN Phosphohydrolase - genetics | ras Proteins - genetics | Cell Proliferation | Proto-Oncogene Proteins B-raf - physiology | Humans | Proto-Oncogene Proteins c-akt - physiology | Signal Transduction - genetics | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Phosphatidylinositol 3-Kinases - genetics | Thyroid Neoplasms - physiopathology | Thyroid Neoplasms - genetics | MAP Kinase Signaling System - genetics | Mitogen-Activated Protein Kinases - physiology | Cell Transformation, Neoplastic | Phosphatidylinositol 3-Kinases - physiology | Mitogen-Activated Protein Kinases - genetics | Signal Transduction - physiology | Extracellular Signal-Regulated MAP Kinases - physiology | Gene Expression Regulation, Neoplastic - physiology | ras Proteins - physiology
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3. Full Text Diagnostic and Prognostic Markers in Differentiated Thyroid Cancer
by Jose M. Gomez Saez
Current Genomics, ISSN 1389-2029, 12/2011, Volume 12, Issue 8, pp. 597 - 608
The MAPK/ERK (mitogen-activated protein kinase/extracellular signal- regulated kinase signaling pathway) and PI3K/Akt (lipid kinase phoshoinositide-3-kinase... 
RET | Pi3k | RAS | PTEN | AKT | BRAF | Differentiated thyroid cancer | MOLECULAR CHARACTERIZATION | HISTONE DEACETYLASE INHIBITOR | RET/PTC REARRANGEMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | BRAF V600E MUTATION | differentiated thyroid cancer | PAPILLARY CARCINOMAS | PI3K | NEEDLE-ASPIRATION BIOPSY | PAX8-PPAR-GAMMA REARRANGEMENT | GENETICS & HEREDITY | CLINICAL-IMPLICATIONS | FOLLICULAR VARIANT | ENDOTHELIAL GROWTH-FACTOR
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4. Full Text Fluorescent Protein-based Biosensors to Visualize Signal Transduction beneath the Plasma Membrane
by FUJIOKA, Yoichiro and NANBO, Asuka and NISHIDE, Shin-ya and OHBA, Yusuke
Analytical Sciences, ISSN 0910-6340, 2015, Volume 31, Issue 4, pp. 267 - 274
In response to extracellular stimuli, cells display a variety of behaviors, including proliferation, differentiation, morphological changes and migration. The... 
endocytosis | FRET | biosensor | PI3K | Fluorescent protein | Ras | Endocytosis | Biosensor | CHEMISTRY, ANALYTICAL | ACTIVATION | PLECKSTRIN-HOMOLOGY-DOMAIN | SENSOR | SINGLE LIVING CELLS | GREEN | DYNAMIC-RANGE | IN-VIVO | NEURAL ACTIVITY | ENERGY-TRANSFER | CA2+ INDICATORS | Biosensing Techniques - methods | Molecular Imaging - methods | Cell Membrane - metabolism | Signal Transduction | Luminescent Proteins - metabolism
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