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Journal of allergy and clinical immunology, ISSN 0091-6749, 02/2017, Volume 139, Issue 2, pp. 597 - 606.e4
Background Activated phosphoinositide 3-kinase δ syndrome (APDS) is a recently described combined immunodeficiency resulting from gain-of-function mutations... 
Allergy and Immunology | Recurrence | Humans | Middle Aged | Child, Preschool | Infant | Male | Antibiotic Prophylaxis | Class I Phosphatidylinositol 3-Kinases/antagonists & inhibitors | Young Adult | Immunoglobulins, Intravenous/therapeutic use | Enzyme Inhibitors/therapeutic use | Lymphoproliferative Disorders/genetics | Adult | Female | Surveys and Questionnaires | Child | Respiratory Tract Infections/genetics | Mutation/genetics | Hematopoietic Stem Cell Transplantation | International Cooperation | Herpesviridae Infections/genetics | Animals | Adolescent | Survival Analysis | Mice | Immunologic Deficiency Syndromes/genetics | Cohort Studies | Activated phosphoinositide 3-kinase δ syndrome | hematopoietic stem cell transplantation | phosphoinositide 3-kinase δ | immunodeficiency | phosphoinositide 3-kinase inhibitor | PIK3CD gene | bronchiectasis | p110δ-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Class I Phosphatidylinositol 3-Kinases - genetics | Herpesviridae Infections - mortality | Respiratory Tract Infections - genetics | Lymphoproliferative Disorders - therapy | Respiratory Tract Infections - mortality | Respiratory Tract Infections - therapy | Immunologic Deficiency Syndromes - mortality | Herpesviridae Infections - genetics | Immunologic Deficiency Syndromes - therapy | Lymphoproliferative Disorders - genetics | Mutation - genetics | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Enzyme Inhibitors - therapeutic use | Lymphoproliferative Disorders - mortality | Herpesviridae Infections - therapy | Immunoglobulins, Intravenous - therapeutic use | Immunologic Deficiency Syndromes - genetics | Index Medicus | Abridged Index Medicus | Immune Deficiencies, Infection, and Systemic Immune Disorders | HSCT, Hematopoietic stem cell transplantation | BALF, Bronchoalveolar lavage fluid | CT, Computed tomography | APDS, Activated phosphoinositide-3 kinase δ syndrome | GOF, Gain of function | PI3K, Phosphoinositide 3-kinase | HSV, Herpes simplex virus | CMV, Cytomegalovirus | OR, Odds ratio | PPV, Pneumococcal polysaccharide vaccine | CNS, Central nervous system
Journal Article
European urology, ISSN 0302-2838, 2017, Volume 71, Issue 6, pp. 858 - 862
... the human kinome in the UCC cell line RT112 ( FGFR3 - TACC3 translocation). We identified multiple members of the phosphoinositide 3-kinase (PI3K... 
Urology | Synergy | PI3K | FGFR | Bladder cancer | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Class I Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases - metabolism | Humans | Urinary Bladder Neoplasms - enzymology | Molecular Targeted Therapy | Urothelium - pathology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Transfection | Urinary Bladder Neoplasms - genetics | RNA Interference | Time Factors | Carcinoma - enzymology | Receptors, Fibroblast Growth Factor - genetics | Urinary Bladder Neoplasms - pathology | Urothelium - enzymology | Benzamides - pharmacology | Carcinoma - pathology | Pyrazoles - pharmacology | Carcinoma - drug therapy | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Morpholines - pharmacology | Urinary Bladder Neoplasms - drug therapy | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Piperazines - pharmacology | Drug Synergism | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Signal Transduction - drug effects | Tumor Burden - drug effects | Mice, Nude | Aminopyridines - pharmacology | Receptors, Fibroblast Growth Factor - metabolism | Cell Line, Tumor | Carcinoma - genetics | Protein Kinase Inhibitors - pharmacology | Mutation | Urothelium - drug effects | Tyrosine | Epidermal growth factor | Carcinoma | Lung cancer | Therapeutics | Fibroblast growth factors | Protein kinases | Genetic screening | Homeopathy | Materia medica and therapeutics | Cancer | Index Medicus
Journal Article
Blood, ISSN 1528-0020, 01/2014, Volume 123, Issue 2, pp. 239 - 248
Journal Article