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Oncotarget, ISSN 1949-2553, 05/2016, Volume 7, Issue 22, pp. 33440 - 33450
Journal Article
Gene, ISSN 0378-1119, 05/2019, Volume 698, pp. 120 - 128
Phosphatidylinositol 3-kinases (PI3Ks) are crucial coordinators of intracellular signalling in response to the extracellular stimulators. Hyperactivation of... 
Signalling pathway | PTEN | PI3Ks | Cancer | PROTEIN-KINASE B/AKT | PTEN LOSS | AKT ACTIVATION | ENDOMETRIAL CARCINOMA | HUMAN OVARIAN | PHOSPHATIDYLINOSITOL 3'-KINASE | PIK3CA GENE | GENETICS & HEREDITY | PI3K-AKT PATHWAY | UP-REGULATION | TUMOR-GROWTH
Journal Article
Journal Article
Cell Adhesion & Migration, ISSN 1933-6918, 07/2015, Volume 9, Issue 4, pp. 317 - 324
Tumor metastasis is not only a sign of disease severity but also a major factor causing treatment failure and cancer-related death. Therefore, studies on the... 
anti-cancer therapy | tumor aggressiveness | PI3K/Akt signaling pathway | transcription factors | EMT | extracellular matrix | Tumor aggressiveness | Extracellular matrix | Transcription factors | Anti-cancer therapy | 3-phosphoinositide-dependent protein kinase 1 | multidrug resistance | YB-1 | PANCREATIC-CANCER | ILK | platelet-derived growth factor | GSK-3 | cytokeratin | TNF | bHLH | fibroblast growth factor | PI3K | mesenchymal-epithelial transition | GASTRIC-CANCER | Y-box binding protein-1 | Akt signaling pathway | epithelial-mesenchymal transition | MDR | integrin-linked kinase | protein kinase A | NF-KAPPA-B | protein kinase C | protein kinase B | PDK1 | CARCINOMA-CELLS | FGF | AKT ACTIVATION | phosphatidylinositol-3-kinase | PKB | PKA | E-CADHERIN EXPRESSION | PKC | BREAST-CANCER-CELLS | ECM | basic helix-loop-helix protein | TGF | tumor necrosis factor | PDGF | COLORECTAL-CANCER | transforming growth factor | MULTIDRUG-RESISTANCE | MET | glycogen synthase kinase 3 | Phosphatidylinositol 3-Kinases - genetics | Animals | Epithelial-Mesenchymal Transition - physiology | Humans | Signal Transduction - physiology | Phosphatidylinositol 3-Kinases - metabolism | Signal Transduction - genetics | Epithelial-Mesenchymal Transition - genetics | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins c-akt - genetics
Journal Article
世界胃肠病学杂志:英文版, ISSN 1007-9327, 2015, Volume 21, Issue 43, pp. 12261 - 12273
Frequent activation of phosphatidylinositol-3 kinases(PI3K)/Akt/m TOR signaling pathway in gastric cancer(GC) is gaining immense popularity with identification... 
Epidemiology;Gastric | pathwa | cancer;PI3K/Akt | m | TOR | Targeted therapy | Epidemiology | Gastric cancer | Predictive biomarkers | PI3K/AKT/ MTOR pathway | CANCER-CELLS | MAMMALIAN TARGET | ADVANCED SOLID TUMORS | CELL-CYCLE PROGRESSION | ANTITUMOR-ACTIVITY | PI3K/Akt/mTOR pathway | AKT/PROTEIN KINASE-B | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR | PHOSPHOINOSITIDE 3-KINASES | GASTROENTEROLOGY & HEPATOLOGY | NF-KAPPA-B | PHASE-I | TOR Serine-Threonine Kinases - metabolism | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Drug Discovery - methods | Stomach Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Proto-Oncogene Proteins c-akt - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Carcinoma - enzymology | Biomarkers, Tumor - metabolism | Biomarkers, Tumor - antagonists & inhibitors | Carcinoma - pathology | Proto-Oncogene Proteins c-akt - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Precision Medicine | Carcinoma - drug therapy | Stomach Neoplasms - enzymology | Stomach Neoplasms - genetics | Treatment Outcome | Stomach Neoplasms - drug therapy | Animals | Phosphatidylinositol 3-Kinase - genetics | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Carcinoma - genetics | Biomarkers, Tumor - genetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | PI3K | mTOR pathway | Akt | Topic Highlight
Journal Article