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Journal of Pediatric Hematology/Oncology, ISSN 1077-4114, 2018, Volume 40, Issue 3, pp. e191 - e194
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 07/2017, Volume 54, Issue 5, pp. 3131 - 3136
Journal Article
NeuroMolecular Medicine, ISSN 1535-1084, 06/2016, Volume 18, Issue 2, pp. 155 - 156
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 05/2019, Volume 77, pp. 178 - 182
Genetic case-control association studies are often based on clinically ascertained cases and population or convenience controls. It is known that some of the... 
Biomarkers | Genetics | Diagnosis | Alzheimer | RISK SCORE ANALYSIS | DISEASE | ASSOCIATION | CLU | NEUROSCIENCES | PICALM | GERIATRICS & GERONTOLOGY
Journal Article
by Hollingworth, P and Harold, D and Sims, R and Gerrish, A and Lambert, J.C and Carrasquillo, M.M and Abraham, R and Hamshere, M.L and Pahwa, J.S and Moskvina, V and Dowzell, K and Jones, N and Stretton, A and Thomas, C and Richards, A and Ivanov, D and Widdowson, C and Chapman, J and Lovestone, S and Powell, J and Proitsi, P and Lupton, M.K and Brayne, C and Rubinsztein, D.C and Gill, M and Lawlor, B and Lynch, A and Brown, K.S and Passmore, P.A and Craig, D and McGuinness, B and Todd, S and Holmes, C and Mann, D and Smith, A.D and Beaumont, H and Warden, D and Wilcock, G and Love, S and Kehoe, P.G and Hooper, N.M and Vardy, E.R.L.C and Hardy, J and Mead, S and Fox, N.C and Rossor, M and Collinge, J and Maier, W and Jessen, F and Ruther, E and Schurmann, B and Heun, R and Kolsch, H and van den Bussche, H and Heuser, I and Kornhuber, J and Wiltfang, J and Dichgans, M and Frolich, L and Hampel, H and Gallacher, J and Hull, M and Rujescu, D and Giegling, I and Goate, A.M and Kauwe, J.S.K and Cruchaga, C and Nowotny, P and Morris, J.C and Mayo, K and Sleegers, K and Bettens, K and Engelborghs, S and de Deyn, P.P and Van Broeckhoven, C and Livingston, G and Bass, N.J and Gurling, H and McQuillin, A and Gwilliam, R and Deloukas, P and Al-Chalabi, A and Shaw, C.E and Tsolaki, M and Singleton, A.B and Guerreiro, R and Muhleisen, T. W and Nothen, M. M and Moebus, S and Jockel, K.H and Klopp, N and Wichmann, H. E and Pankratz, V.S and Sando, S.B and Aasly, J.O and Barcikowska, M and Wszolek, Z.K and Dickson, D.W and Graff-Radford, N.R. and others and Alzheimer's Dis Neuroimaging and EADI1 Consortium and CHARGE Consortium and Alzheimer's Disease Neuroimaging Initiative and EADI1 consortium and CHARGE consortium and the Alzheimer's Disease Neuroimaging Initiative
Nature Genetics, ISSN 1061-4036, 2011, Volume 43, Issue 5, pp. 429 - 435
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 8/2015, Volume 52, Issue 1, pp. 399 - 413
Alzheimer’s disease (AD) is a highly heritable disease (with heritability up to 76 %) with a complex genetic profile of susceptibility, among which large... 
Neurology | Neurosciences | Biomedicine | Amyloid beta | Alzheimer’s disease | Neurobiology | Genetics | Mechanism | Cell Biology | PICALM | Polymorphism
Journal Article
by Han, ZJ and Qu, JJ and Zhao, JH and Zou, X
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2018, Volume 8, Issue 1, pp. 11062 - 11062
Clusterin (CLU) is considered one of the most important roles for pathogenesis of Alzheimer's Disease (AD). The early genome-wide association studies (GWAS)... 
IDENTIFIES VARIANTS | GENOTYPE | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | PICALM POLYMORPHISMS | CLUSTERIN | RISK SCORE | CR-1 | MEDICINE | GENE POLYMORPHISMS | GENOME-WIDE ASSOCIATION
Journal Article
Alzheimer's and Dementia, ISSN 1552-5260, 2019
Introduction: Genome-wide association studies (GWAS) discovered multiple late-onset Alzheimer's disease (LOAD)-associated SNPs and inferred the genes based on... 
GWAS | Virtual circular chromosomal conformation capture (4C) | BIN1 | CELF1 | Chromatin state segmentation | Late-onset Alzheimer's disease | CTCF | PICALM
Journal Article
Journal of Periodontology, ISSN 0022-3492, 07/2019, Volume 90, Issue 7, pp. 775 - 787
Physiological roles for the periodontal ligament (PDL) include tooth eruption and anchorage, force absorption, and provision of proprioceptive information.... 
periodontal ligament | permanent dentition | deciduous tooth | proteomics | gene expression | cell membrane | DENTISTRY, ORAL SURGERY & MEDICINE | ROOT-RESORPTION | TOOTH | EXPRESSION | PICALM
Journal Article
AUTOPHAGY, ISSN 1554-8627, 04/2014, Volume 10, Issue 4, pp. 694 - 696
We have reported previously that autophagy is responsible for amyloid precursor protein-C-terminal fragment (APP-CTF) degradation and therefore A clearance. To... 
beta-amyloid | APP | endosome | AP2 | Alzheimer disease | endocytosis | LC3 | autophagosome | autophagy receptor | PICALM | CELL BIOLOGY
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e58618 - e58618
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 12/2014, Volume 54, Issue 4, pp. 780 - 786
Alzheimer’s disease (AD) is the most common form of dementia in older population. Growing evidence of genetic background that predisposes individuals to AD has... 
Neurochemistry | Neurology | Neurosciences | Biomedicine | CR1 | Alzheimer’s disease | BIN1 | Proteomics | APOE | Cell Biology | PICALM
Journal Article
HUMAN MOLECULAR GENETICS, ISSN 0964-6906, 09/2016, Volume 25, Issue 18, pp. 3988 - 3997
Aberrant production, clearance and deposition of amyloid-beta protein (A beta) in the human brain have been implicated in the aetiology of Alzheimer disease... 
CLATHRIN-MEDIATED ENDOCYTOSIS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTATION | GENETICS & HEREDITY | A-BETA | TRAFFICKING | PRECURSOR PROTEIN | PLAQUES | MATURATION | EXPRESSION | PICALM
Journal Article
BMC Neuroscience, ISSN 1471-2202, 12/2016, Volume 17, Issue 1
Journal Article
International Journal of Clinical and Experimental Medicine, 06/2016, Volume 9, Issue 6, pp. 10135 - 10146
Journal Article
NeuroMolecular Medicine, ISSN 1535-1084, 03/2014, Volume 16, Issue 1, pp. 150 - 160
The success of future intervention strategies for Alzheimer's disease (AD) will likely rely on the development of treatments starting early in the disease...