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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 30, pp. 7641 - 7643
Journal Article
SCIENCE, ISSN 0036-8075, 05/2018, Volume 360, Issue 6388, pp. 492 - 493
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 07/2019, Volume 116, Issue 28, pp. 14260 - 14269
Journal Article
American Journal of Medical Genetics, Part A, ISSN 1552-4825, 2019, Volume 179, Issue 6, pp. 1034 - 1041
The group of distal arthrogryposis (DA) disorders is characterized by congenital contractures of the distal joints. In most instances, these are genetic... 
distal arthrogryposis | Piezo2 | restrictive pulmonary function | mechanotransduction | arthrogryposis multiple | IIB | CHANNEL PIEZO2 | CONTRACTURES | FORM | PROPRIOCEPTION | DELINEATION | GENETICS & HEREDITY | GORDON SYNDROME | MUTATIONS | PROTEINS | Genetic disorders | Pathogenicity | Phenotypes | Proprioception | Ophthalmoplegia | Muscles | Arthrogryposis | Mutation
Journal Article
Cell Reports, ISSN 2211-1247, 12/2017, Volume 21, Issue 11, pp. 3102 - 3115
Mechanical and thermal hyperalgesia (pain hypersensitivity) are cardinal signs of inflammation. Although the mechanism underlying thermal hyperalgesia is well... 
CHRNA3 | mechanically insensitive nociceptor | MIA | nerve growth factor | mechanotransduction | inflammatory pain | Piezo2 | hyperalgesia | NGF | silent nociceptor
Journal Article
Cell Reports, ISSN 2211-1247, 02/2019, Volume 26, Issue 6, pp. 1419 - 1431.e4
Touch and mechanical pain represent distinct, but interactive, modalities of mechanosensation. However, the molecular mechanisms underlying these... 
mechanosensitive ion channels | pain | DRG | touch | Piezo2 | Piezo1 | mechanosensation | proprioception | NEURONS | CELL BIOLOGY
Journal Article
Journal Article
Advanced Materials, ISSN 0935-9648, 04/2017, Volume 29, Issue 13, p. n/a
An ultrasensitive, visco‐poroelastic artificial mechanotransducer skin over a wide spectrum of pressure is effectively demonstrated by directly mimicking the... 
ultrasensitive artificial skin | ionic mechanotransducer | Piezo2 protein channel | visco‐poroelastic | Skin | Mammals | Tactile
Journal Article
The Journal of Physiology, ISSN 0022-3751, 01/2017, Volume 595, Issue 1, pp. 3 - 3
Journal Article
Science Translational Medicine, ISSN 1946-6234, 10/2018, Volume 10, Issue 462, p. eaat9897
The brush of a feather and a pinprick are perceived as distinct sensations because they are detected by discrete cutaneous sensory neurons. Inflammation or... 
MEDICINE, RESEARCH & EXPERIMENTAL | NEUROPATHIC PAIN | HAIRY SKIN | SENSITIZATION | NOCICEPTORS | MOUSE | ANIMAL-MODELS | TOUCH SENSATION | HYPERALGESIA | SENSORY NEURONS | MECHANOTRANSDUCTION | CELL BIOLOGY
Journal Article
Neuron, ISSN 0896-6273, 12/2018, Volume 100, Issue 6, pp. 1272 - 1274
Gentle touch sensation in mammals depends on synaptic transmission from primary sensory cells (Merkel cells) to secondary sensory neurons. identify... 
PIEZO2 | MERKEL CELLS | NEUROSCIENCES | Pain perception | Dopamine | Neurons | Nervous system | Tactile stimuli | Proteins | Neurotransmitters | Pain | Synaptic transmission | Sensory neurons | Skin | Norepinephrine | Communication
Journal Article
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 3, pp. 701 - 708
Neuronal mechano-sensitivity relies on mechano-gated ion channels, but pathways regulating their activity remain poorly understood. TMEM150C was proposed to... 
trigeminal ganglia | Tentonin3 | TREK-1 | mechano-transduction | Piezo2 | Piezo1 | mechano-receptor | TMEM150C | K2P2.1 | mechano-sensitivity | PERCEPTION | XEROCYTOSIS | MEMBRANE | MECHANOSENSITIVITY | TRAAK | PIEZO1 | TOUCH | K+ CHANNELS | MECHANOTRANSDUCTION | CELL BIOLOGY
Journal Article
ELIFE, ISSN 2050-084X, 03/2018, Volume 7
Piezo2 ion channels are critical determinants of the sense of light touch in vertebrates. Yet, their regulation is only incompletely understood. We recently... 
MTMR2 | PIKFYVE | MARIE-TOOTH-DISEASE | MEMBRANE PHOSPHOINOSITIDES | PHOSPHATASE-ACTIVITY | BIOLOGY | RECEPTOR TRAFFICKING | PIEZO2 | TOUCH SENSATION | MECHANOSENSITIVE CURRENTS | ION CHANNELS
Journal Article
Neuromuscular Disorders, ISSN 0960-8966, 01/2019, Volume 29, Issue 1, pp. 75 - 79
mutations have been described in dominant arthrogryposis, but homozygous mutations of may also be responsible for more complex clinical patterns, associating... 
PIEZO2 | Proprioceptive impairment | Arthrogryposis | CHANNEL | DISTAL ARTHROGRYPOSIS | ATAXIA | NEUROSCIENCES | CLINICAL NEUROLOGY | Heart | Scoliosis | Creatine kinase | Genetic research | Genetic aspects | Pulmonary function tests | Creatine
Journal Article