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Aging cell, ISSN 1474-9718, 04/2009, Volume 8, Issue 2, pp. 162 - 177
Summary Age‐related macular degeneration (AMD) is characterized by the formation of drusen, extracellular deposits associated with atrophy of the retinal... 
aging | retina | degeneration | oxidative stress | tight junction | Aging | Oxidative stress | Retina | Tight junction | Degeneration | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Cell Biology | Hypertrophy - chemically induced | Retinal Pigment Epithelium - metabolism | Reactive Oxygen Species - metabolism | Peptide Fragments - toxicity | Humans | Oxidative Stress - physiology | Photoreceptor Cells, Vertebrate - drug effects | Carrier Proteins - drug effects | Membrane Potential, Mitochondrial - drug effects | Hypertrophy - metabolism | Hypertrophy - physiopathology | Retinal Pigment Epithelium - pathology | Amyloid beta-Peptides - metabolism | Membrane Potential, Mitochondrial - physiology | cis-trans-Isomerases | Retinal Pigment Epithelium - drug effects | Tight Junctions - drug effects | Tight Junctions - metabolism | Cell Line | Peptide Fragments - metabolism | Cytoskeleton - pathology | Macular Degeneration - physiopathology | Amyloid beta-Peptides - toxicity | Mice, Inbred C57BL | Aging - pathology | Macular Degeneration - metabolism | Animals | Carrier Proteins - metabolism | Eye Proteins - metabolism | Cytoskeleton - metabolism | Eye Proteins - drug effects | Mice | Macular Degeneration - chemically induced | Oxidative Stress - drug effects | Photoreceptor Cells, Vertebrate - metabolism | Photoreceptor Cells, Vertebrate - pathology | Cytoskeleton - drug effects | Tight Junctions - pathology | Aging - metabolism | Index Medicus
Journal Article
International journal of molecular medicine, ISSN 1107-3756, 07/2018, Volume 42, Issue 1, pp. 123 - 130
NADPH oxidases (NOXs) are important in the pathophysiology of fibrotic diseases. The expression and activity of NOXs are regulated by growth factors, including... 
Retinal pigment epithelial cells | α-smooth muscle actin | NADPH oxidase 4 | Epithelialto-mesenchymal transition | Proliferation | VAS2870 | Cyclin D1 | E-cadherin | Proliferative vitreoretinopathy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine
Journal Article
Ophthalmology (Rochester, Minn.), ISSN 0161-6420, 11/2018, Volume 125, Issue 11, pp. 1765 - 1775
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e69563 - e69563
.... The degeneration of retinal pigment epithelial cells (RPE) causes secondarily adverse effects on neural retina leading to visual loss... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | ELAV-Like Protein 1 | Immunohistochemistry | Retinal Pigment Epithelium - metabolism | Immunoprecipitation | Sequestosome-1 Protein | Epithelial Cells - drug effects | Humans | Autophagy | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Proteasome Endopeptidase Complex - drug effects | RNA Interference | Epithelial Cells - cytology | Retinal Pigment Epithelium - drug effects | Cell Line | Microscopy, Electron, Transmission | ELAV Proteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Leupeptins - pharmacology | Aminoimidazole Carboxamide - analogs & derivatives | Adaptor Proteins, Signal Transducing - genetics | Proteasome Endopeptidase Complex - metabolism | Adaptor Proteins, Signal Transducing - metabolism | ELAV Proteins - genetics | Retinal Pigment Epithelium - cytology | Macular degeneration | Proteins | RNA | Proteolysis | Genes | Genetic transcription | Protein binding | Post-transcription | Oxidative stress | Disabled people | Disease | Laboratories | Lipid peroxidation | Retina | Biology | Kinases | Accumulation | Retinal pigment epithelium | Older people | Aging | Inhibition | Age | HuR protein | Cleaning | Pharmacology | Gene expression | Medicine | Studies | Pathology | Hospitals | Molecular modelling | Aggregates | Proteasomes | Clinical medicine | Phagocytosis | Geriatrics | Apoptosis | Index Medicus
Journal Article