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Cancer, ISSN 0008-543X, 08/2014, Volume 120, Issue 15, pp. 2316 - 2324
Journal Article
Asian Biomedicine, ISSN 1875-855X, 12/2019, Volume 13, Issue 1, pp. 33 - 36
Abstract Background Macrodactyly is a rare congenital deformity characterized by gigantism of all structures of the digits. Previous reports showed that the... 
macrodactyly | PIK3CA | mutation
Journal Article
Oncogene, ISSN 0950-9232, 09/2008, Volume 27, Issue 42, pp. 5648 - 5650
The serine-threonine kinase AKT1 is a central player in the oncogenic pathway controlled by PI3K. Recently, a somatic mutation in AKT1 (E17K) has been detected... 
AKT1 | Mutation | PIK3CA | Cancer | Signal transduction | Oncology | Genetics | Kinases | Tumors
Journal Article
Oncotarget, ISSN 1949-2553, 08/2018, Volume 9, Issue 60, pp. 31709 - 31718
Phosphatidylinositol 3-kinase (PI3K) pathway activation is associated with resistance to paclitaxel in solid tumors. We assessed the safety and activity of... 
Human | PIK3CA protein | Chemotherapy | Breast neoplasms | Drug resistance
Journal Article
Annals of oncology, ISSN 0923-7534, 01/2017, Volume 28, Issue 1, pp. 128 - 135
BackgroundWe performed whole-exome sequencing of pretreatment biopsies and examined whether genome-wide metrics of overall mutational load, clonal... 
Breast cancer NeoALTTO trial | PIK3CA-related network | Regulation of RhoA activity | Whole-exome sequencing | Index Medicus
Journal Article
Cell cycle (Georgetown, Tex.), ISSN 1551-4005, 10/2014, Volume 3, Issue 10, pp. 1221 - 1224
Journal Article
JAAD Case Reports, ISSN 2352-5126, 11/2018, Volume 4, Issue 10, pp. 1080 - 1082
Journal Article
Oncotarget, ISSN 1949-2553, 06/2019, Volume 10, Issue 41, pp. 4107 - 4124
Whole exome sequencing (WES) recently identified frequent mutations in the genes of GPCR-mediated PI3K pathway ( , , and ) in a Chinese population with... 
Journal Article
BMC cancer, ISSN 1471-2407, 03/2017, Volume 17, Issue 1, pp. 211 - 211
Background: We designed a single-arm, open-label phase II trial of everolimus in PIK3CA amplification/mutation and/or PTEN loss patients with advanced solid... 
PTEN loss | Everolimus | PIK3CA amplification/mutation | Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus
Journal Article