X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (903) 903
Book Review (197) 197
Publication (120) 120
Book Chapter (12) 12
Dissertation (3) 3
Conference Proceeding (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (732) 732
humans (655) 655
pik3ca (463) 463
female (430) 430
oncology (430) 430
mutation (417) 417
cancer (322) 322
phosphatidylinositol 3-kinases - genetics (244) 244
genetic aspects (233) 233
male (222) 222
class i phosphatidylinositol 3-kinases (214) 214
middle aged (213) 213
pik3ca mutations (208) 208
aged (196) 196
adult (176) 176
tumors (175) 175
breast cancer (170) 170
research (161) 161
prognosis (155) 155
colorectal cancer (151) 151
mutations (150) 150
animals (143) 143
analysis (142) 142
phosphatidylinositol 3-kinases - metabolism (141) 141
kinases (134) 134
kras (119) 119
expression (118) 118
care and treatment (116) 116
gene mutations (116) 116
pik3ca gene (116) 116
signal transduction (116) 116
cell line, tumor (113) 113
health aspects (112) 112
chemotherapy (110) 110
metastasis (110) 110
pik3ca mutation (107) 107
pathway (105) 105
pi3k (104) 104
colorectal neoplasms - genetics (100) 100
pathology (100) 100
neoplasms (99) 99
article (98) 98
proto-oncogene proteins c-akt - metabolism (98) 98
braf (96) 96
cell biology (96) 96
genes (96) 96
proteins (96) 96
biochemistry & molecular biology (94) 94
pten (94) 94
aged, 80 and over (90) 90
survival (90) 90
gene (89) 89
breast-cancer (88) 88
breast neoplasms - genetics (86) 86
genetics & heredity (85) 85
high-frequency (81) 81
mice (80) 80
akt (79) 79
biomarkers, tumor - genetics (79) 79
dna mutational analysis (79) 79
gene expression (77) 77
carcinoma (75) 75
genetic research (74) 74
immunohistochemistry (74) 74
patients (74) 74
colorectal neoplasms - pathology (73) 73
medicine & public health (73) 73
phosphorylation (72) 72
breast neoplasms - pathology (71) 71
apoptosis (69) 69
cancer therapies (69) 69
egfr (69) 69
proto-oncogene proteins b-raf - genetics (69) 69
breast neoplasms - drug therapy (67) 67
cancer research (67) 67
antineoplastic agents - therapeutic use (66) 66
genetics (66) 66
phosphatidylinositol 3-kinases - antagonists & inhibitors (66) 66
research article (66) 66
resistance (65) 65
signal transduction - drug effects (64) 64
gene expression regulation, neoplastic (63) 63
microsatellite instability (63) 63
colon-cancer (62) 62
therapy (62) 62
development and progression (61) 61
growth (61) 61
mutation - genetics (61) 61
medical prognosis (60) 60
neoplasm staging (60) 60
biomarkers (59) 59
proto-oncogene proteins c-akt - genetics (58) 58
antineoplastic agents - pharmacology (57) 57
phosphoinositide 3-kinase (57) 57
1-phosphatidylinositol 3-kinase (56) 56
activation (56) 56
deoxyribonucleic acid--dna (54) 54
pten phosphohydrolase - genetics (54) 54
genomics (53) 53
multidisciplinary sciences (53) 53
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Science Translational Medicine, ISSN 1946-6234, 03/2016, Volume 8, Issue 332, pp. 332ra43 - 332ra43
Journal Article
NATURE GENETICS, ISSN 1061-4036, 05/2014, Volume 46, Issue 5, pp. 510 - 515
Activating mutations in genes encoding phosphatidylinositol 3-kinase (PI3K)-AKT pathway components cause... 
NEOCORTEX | PIK3CA | AKT3 | GENETICS & HEREDITY | MICE | INTERMEDIATE PROGENITOR CELLS | CEREBRAL-CORTEX
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 02/2017, Volume 35, Issue 5, pp. 569 - 569
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2018, Volume 128, Issue 4, pp. 1496 - 1508
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2019, Volume 39, Issue 3, pp. 496 - 512
OBJECTIVE—Venous malformations (VMs) arise from developmental defects of the vasculature and are characterized by massively enlarged and tortuous venous... 
DIAGNOSIS | endothelial cells | cell proliferation | PIK3CA CAUSE | apoptosis | COMBINATION | CHRONIC MYELOID-LEUKEMIA | VASCULAR ANOMALIES | mutation | PATHWAY | PERIPHERAL VASCULAR DISEASE | umbilical vein | HEMATOLOGY | LYMPHATIC ENDOTHELIAL-CELLS | ABL KINASES | ACTIVATING MUTATIONS | SIROLIMUS | Translational Sciences | 10191 | 10053 | 10041 | 10054 | 10012
Journal Article
Journal Article
NATURE, ISSN 0028-0836, 06/2018, Volume 558, Issue 7711, pp. 522 - 525
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, pp. e36402 - e36402
The PTEN/PI3K pathway is commonly mutated in cancer and therefore represents an attractive target for therapeutic intervention. To investigate the primary... 
EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER CELLS | I PHOSPHATIDYLINOSITIDE 3-KINASES | POTENT | PIK3CA MUTATIONS | KINASE | BIOLOGY | GENE-EXPRESSION | INHIBITOR | ONCOGENIC PATHWAYS | LINES | Neoplasms - metabolism | Humans | Gene Silencing | Cell Survival - genetics | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Epithelial-Mesenchymal Transition - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Sulfonamides - pharmacology | Cell Movement - genetics | Indazoles - pharmacology | Phosphatidylinositol 3-Kinases - genetics | Phenotype | Class I Phosphatidylinositol 3-Kinases | Neoplasms - genetics | RNA Interference | Signal Transduction - drug effects | Protein Interaction Domains and Motifs - genetics | Cell Line, Tumor | Mutation | Enzyme Activation - genetics | Cluster Analysis | Medicine, Experimental | Medical research | Genetic aspects | Metastasis | Health aspects | TOR protein | Cell culture | Mesenchyme | Laboratories | Epithelial cells | Reversing | Oncology | AKT protein | Kinases | Positive feedback | Metastases | Genotype & phenotype | Cell growth | Penicillin | Phosphatidylinositol 3,4,5-triphosphate | Invasiveness | Pharmacology | Breast cancer | Gene expression | Chemical compounds | Insulin | 1-Phosphatidylinositol 3-kinase | Signaling | Alleles | PTEN protein | Cancer | Index Medicus
Journal Article
Genetics in Medicine, ISSN 1098-3600, 09/2017, Volume 19, Issue 9, pp. 989 - 997
Journal Article