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1. Astrocytes
: normal, reactive, and neoplastic
by Duffy, Philip E
1983, ISBN 9780890049969, xi, 224
Gliomas | Astrocytes
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2. Full Text Pilocytic astrocytoma: pathology, molecular mechanisms and markers
by Collins, V. Peter and Jones, David T. W and Giannini, Caterina
Acta Neuropathologica, ISSN 0001-6322, 06/2015, Volume 129, Issue 6, pp. 775 - 788
Pilocytic astrocytomas (PAs) were recognized as a discrete clinical entity over 70 years ago. They are relatively benign (WHO grade I) and have, as a group, a... 
Histopathology | Immunocytochemistry | Morphology | Pilocytic astrocytoma | Brain neoplasms | Molecular pathology | MAPK | Oncogenes | SURVIVAL RATES | LOW-GRADE ASTROCYTOMAS | OPTIC PATHWAY | PATHOLOGY | SPINAL-CORD ASTROCYTOMA | PEDIATRIC ASTROCYTOMAS | NEUROSCIENCES | NOONAN-SYNDROME | CLINICAL NEUROLOGY | GLIONEURONAL TUMORS | BRAF FUSION GENE | MAPK PATHWAY | NEUROFIBROMATOSIS TYPE-1 | Astrocytoma - genetics | Neuroimaging | Astrocytoma - pathology | Astrocytoma - physiopathology | Central Nervous System Neoplasms - pathology | Central Nervous System Neoplasms - physiopathology | Genetic Predisposition to Disease | Molecular Biology | Central Nervous System Neoplasms - genetics | Humans | Models, Molecular | Genomics | Review
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3. Full Text Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma
by Korshunov, Andrey and Meyer, Jochen and Capper, David and Christians, Arne and Remke, Marc and Witt, Hendrik and Pfister, Stefan and von Deimling, Andreas and Hartmann, Christian
Acta Neuropathologica, ISSN 0001-6322, 2009, Volume 118, Issue 3, pp. 401 - 405
Separation of pilocytic astrocytoma from diffuse astrocytomas frequently poses problems mostly related to small sample size. Precise classification and grading... 
Diffuse astrocytoma | BRAF | IDH1 | IDH2 | Pilocytic astrocytoma | ACTIVATION | PATHWAY | MUTATIONS | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | Astrocytoma - genetics | Diagnosis, Differential | Tissue Array Analysis | Brain Neoplasms - diagnosis | Humans | Middle Aged | Brain Neoplasms - genetics | Child, Preschool | In Situ Hybridization, Fluorescence | Isocitrate Dehydrogenase - genetics | Male | Biomarkers, Tumor | Proto-Oncogene Proteins B-raf - genetics | Adolescent | Adult | Female | Aged | Mutation | Astrocytoma - diagnosis | Child
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4. Full Text Increased β-Catenin/Tcf Signaling in Pilocytic Astrocytomas: A Comparative Study to Distinguish Pilocytic Astrocytomas from Low-Grade Diffuse Astrocytomas
by Sareddy, Gangadhara Reddy and Geeviman, Khamushavalli and Panigrahi, Manas and Challa, Sundaram and Mahadevan, Anita and Babu, Phanithi Prakash
Neurochemical Research, ISSN 0364-3190, 1/2012, Volume 37, Issue 1, pp. 96 - 104
Although pilocytic and diffuse grade II astrocytomas considered as low-grade tumors, the distinction between them is still a major clinical problem. Previously... 
Biochemistry, general | Neurochemistry | Neurology | β-catenin | Neurosciences | Diffuse astrocytoma | Biomedicine | Pilocytic astrocytoma | Differential expression | Cell Biology | beta-catenin | TARGET | APOPTOSIS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | IDENTIFICATION | TUMORS | NEUROSCIENCES | GENE | PATHWAY | MICROGLIA | WNT | Astrocytoma - metabolism | Immunohistochemistry | Signal Transduction | Humans | Middle Aged | Brain Neoplasms - pathology | Child, Preschool | Male | beta Catenin - metabolism | Brain Neoplasms - metabolism | TCF Transcription Factors - metabolism | Astrocytoma - pathology | Adolescent | Adult | Female | Child | Signal transduction | Wnt protein | catenin | c-Myc protein | Tcf protein | Astrocytoma | Endothelial cells | Tumors
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5. Full Text MAPK pathway activation in pilocytic astrocytoma
by Jones, David T. W and Gronych, Jan and Lichter, Peter and Witt, Olaf and Pfister, Stefan M
Cellular and Molecular Life Sciences, ISSN 1420-682X, 6/2012, Volume 69, Issue 11, pp. 1799 - 1811
Pilocytic astrocytoma (PA) is the most common tumor of the pediatric central nervous system (CNS). A body of research over recent years has demonstrated a key... 
Biochemistry, general | Senescence | Pilocytic | BRAF | MAPK | LGG | Biomedicine general | Cell Biology | Life Sciences | Life Sciences, general | Low grade glioma | Fusion | Astrocytoma | NEURAL PROGENITORS | OPTIC-GLIOMA FORMATION | VONRECKLINGHAUSEN NEUROFIBROMATOSIS | MALIGNANT ASTROCYTOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR GENE | LOW-GRADE ASTROCYTOMAS | ERK SIGNALING PATHWAY | CELL BIOLOGY | BRAF FUSION GENE | PROGENITOR-CELL | NEUROFIBROMATOSIS TYPE-1 | Astrocytoma - genetics | Astrocytoma - metabolism | Humans | Gene Fusion | MAP Kinase Signaling System | Astrocytoma - pathology | Animals | Proto-Oncogene Proteins B-raf - genetics | Mice | Models, Genetic | Neurofibromin 1 - genetics | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Proto-Oncogene Proteins B-raf - chemistry | Pediatrics | Signal transduction | Nervous system | Cellular biology | Kinases | Cancer | Reviews | Central nervous system | MAP kinase | Gene fusion | Tumors | Review
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6. Full Text cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant
by Louis, David N and Giannini, Caterina and Capper, David and Paulus, Werner and Figarella-Branger, Dominique and Lopes, M Beatriz and Batchelor, Tracy T and Cairncross, J Gregory and van den Bent, Martin and Wick, Wolfgang and Wesseling, Pieter
Acta Neuropathologica, ISSN 0001-6322, 4/2018, Volume 135, Issue 4, pp. 639 - 642
Medicine & Public Health | Pathology | Neurosciences | NERVOUS-SYSTEM | H3 K27M MUTATIONS | TUMOR | PILOCYTIC ASTROCYTOMA | CLASSIFICATION | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | GENETIC ALTERATIONS | Medical colleges | Gliomas | Neurophysiology | Glioma | Astrocytoma | Life Sciences
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7. Full Text A clinicopathologic reappraisal brain stem tumor classification: Identification of pilocytic astrocytoma and fibrillary astrocytoma as distinct entities
by Fisher, Paul G and Breiter, Steven N and Carson, Benjamin S and Wharam, Moody D and Williams, Jeffery A and Weingart, Jon D and Foer, Dana R and Goldthwaite, Patricia T and Tihan, Tarik and Burger, Peter C
Cancer, ISSN 0008-543X, 10/2000, Volume 89, Issue 7, pp. 1569 - 1576
BACKGROUND. Brain stem tumors in children have been classified pathologically as low grade or high grade gliomas and descriptively as diffuse gliomas,... 
Brain neoplasms | Fibrillary astrocytoma | Abducens nerve | Glioma | Brain stem | Pilocytic astrocytoma | PROGNOSTIC FACTORS | GLIOMAS | pilocytic astrocytoma | LONG-TERM SURVIVAL | SURGICAL INDICATIONS | brain neoplasms | fibrillary astrocytoma | abducens nerve | INTRAAXIAL ENDOPHYTIC TUMORS | ONCOLOGY | AND/OR MEDULLA-OBLONGATA | brain stem | ONSET AQUEDUCTAL STENOSIS | MIDBRAIN TUMORS | glioma | CHILDRENS CANCER GROUP | INTRINSIC TECTAL TUMORS | Research | Identification and classification | Brain tumors | Tumors
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8. Full Text Pilocytic Astrocytoma
: A Disease With Evolving Molecular Heterogeneity
by Sadighi, Zsila and Slopis, John
Journal of Child Neurology, ISSN 0883-0738, 5/2013, Volume 28, Issue 5, pp. 625 - 632
Pilocytic astrocytoma, the most common pediatric brain tumor, is a clinically and molecularly heterogeneous disease that occurs most often in the cerebellum... 
MAPK PATHWAY ACTIVATION | pilocytic astrocytoma | KIAA1549-BRAF fusion | cerebellum | CHEMOTHERAPY | CLINICAL NEUROLOGY | CHILDREN | BRAF FUSION GENE | chiasmatic | hypothalamic | LOW-GRADE GLIOMA | molecular aberrations | PEDIATRICS | Rosenthal fibers | DUPLICATION | B-RAF | MUTATIONS | WEEKLY VINBLASTINE | NEUROFIBROMATOSIS TYPE-1 | Hypothalamic Neoplasms - diagnosis | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Transcriptional Activation - genetics | Prognosis | Astrocytoma - therapy | Cerebellar Neoplasms - diagnosis | Humans | Optic Nerve Neoplasms - genetics | Genes, Neurofibromatosis 1 | Molecular Targeted Therapy | Extracellular Signal-Regulated MAP Kinases - genetics | Point Mutation - genetics | Cell Transformation, Neoplastic - genetics | Optic Nerve Neoplasms - diagnosis | Hypothalamic Neoplasms - genetics | Astrocytoma - diagnosis | Child | Optic Chiasm | Optic Nerve Neoplasms - therapy | Hypothalamic Neoplasms - therapy | Astrocytoma - genetics | Brain Neoplasms - diagnosis | Brain Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Cerebellar Neoplasms - genetics | Genetic Heterogeneity | Proto-Oncogene Proteins B-raf - genetics | Brain Neoplasms - therapy | Chromosome Aberrations | Cerebellar Neoplasms - therapy
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9. Full Text Comparative transcriptomics reveals similarities and differences between astrocytoma grades
by Seifert, Michael and Garbe, Martin and Friedrich, Betty and Mittelbronn, Michel and Klink, Barbara
BMC Cancer, ISSN 1471-2407, 12/2015, Volume 15, Issue 1, p. 952
Background: Astrocytomas are the most common primary brain tumors distinguished into four histological grades. Molecular analyses of individual astrocytoma... 
Astrocytoma grades | Diffuse astrocytoma | Anaplastic astrocytoma | Glioblastoma | Pilocytic astrocytoma | STEM-CELLS | DIFFUSE ASTROCYTOMAS | INTEGRATED GENOMIC ANALYSIS | HUMAN GLIOMA-CELLS | PILOCYTIC ASTROCYTOMAS | ONCOLOGY | PHOSPHOGLYCERATE KINASE 1 | ANAPLASTIC ASTROCYTOMAS | MALIGNANT GLIOMAS | GROWTH-FACTOR EXPRESSION | HUMAN GLIOBLASTOMA-MULTIFORME | Astrocytoma - genetics | Immunohistochemistry | Astrocytoma - pathology | Neoplasm Grading | Brain Neoplasms - classification | Humans | Brain Neoplasms - pathology | Transcriptome | Brain Neoplasms - genetics | Astrocytoma - classification | Epigenetic inheritance | Genetic transcription | Research | Analysis | Astrocytoma
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10. Full Text Dysembryoplastic neuroepithelial tumor-like pilocytic astrocytoma: A case report
by Liao, Jia-Ming and Liao, Jia-Ming and Wang, Wei and Wang, Wei and Xie, Jing and Xie, Jing and Wu, Hai-Bo and Wu, Hai-Bo
Medicine, ISSN 0025-7974, 05/2018, Volume 97, Issue 20, p. e10755
Rationale:Pilocytic astrocytoma (PA) typically shows biphasic pattern with a mixture of loose microcystic and compact regions, in which it is not uncommon to... 
fluorescence in situ hybridisation | dysembryoplastic neuroepithelial tumor | KIAA1549-BRAF fusion gene | pilocytic astrocytoma | HETEROGENEITY | MEDICINE, GENERAL & INTERNAL | MUTATION | BRAF | SEPTUM PELLUCIDUM | Case studies | Care and treatment | Diagnosis | Astrocytoma
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11. Full Text Anaplastic pilocytic astrocytoma
by Yong, Eric X.Z and McKelvie, Penny and Murphy, Michael and Wang, Yi Yuen
Journal of Clinical Neuroscience, ISSN 0967-5868, 2014, Volume 21, Issue 11, pp. 1993 - 1996
Abstract This clinical series examines the presentation of three adult patients who were found to have de novo anaplastic pilocytic astrocytoma. Initial... 
Neurology | Anaplastic pilocytic astrocytoma | Adult brain tumour | Neurofibromatosis | Pilocytic astrocytoma | Malignant pilocytic astrocytoma | ACTIVATION | FREQUENT | BRAF ALTERATIONS | PATHWAY | LOW-GRADE ASTROCYTOMAS | NEUROSCIENCES | CLINICAL NEUROLOGY | Immunohistochemistry | Astrocytoma - therapy | Humans | Male | Necrosis | Astrocytoma - complications | Magnetic Resonance Imaging | Mitotic Index | Astrocytoma - pathology | Neoplasm Grading | Brain - pathology | Adult | Female | Astrocytoma - diagnosis | Neurofibromatoses - etiology | Papilledema - etiology
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12. Full Text Posterior fossa pilocytic astrocytoma presenting with opisthotonus in an infant – A case report
by Yates, Charles and Lackey, Alan and Campbell, Robert and McEniery, Jane
Journal of Clinical Neuroscience, ISSN 0967-5868, 10/2019, Volume 68, pp. 338 - 341
Opisthotonus as a presenting feature in neurosurgical patients is rare, with few reports describing such presentations. Only four reports of opisthotonos... 
Paediatric | Tumour | Corticoreticular | Pilocytic astrocytoma | Opisthotonus | NEUROSCIENCES | CLINICAL NEUROLOGY | Medical colleges
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13. Full Text Prognosis and Treatment of Spinal Cord Astrocytoma
by Minehan, Kiernan J., M.D and Brown, Paul D., M.D and Scheithauer, Bernd W., M.D and Krauss, William E., M.D and Wright, Michael P., B.S
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2009, Volume 73, Issue 3, pp. 727 - 733
Purpose To identify the prognostic factors for spinal cord astrocytoma and determine the effects of surgery and radiotherapy on outcome. Methods and Materials... 
Radiology | Hematology, Oncology and Palliative Medicine | Pilocytic | Spinal cord | Radiotherapy | Surgery | Astrocytoma | THERAPY | ONCOLOGY | ADULTS | MALIGNANT ASTROCYTOMAS | RETROSPECTIVE ANALYSIS | TUMORS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Astrocytoma - radiotherapy | Prognosis | Humans | Middle Aged | Male | Treatment Outcome | Combined Modality Therapy | Young Adult | Astrocytoma - pathology | Spinal Cord Neoplasms - mortality | Analysis of Variance | Survival Analysis | Spinal Cord Neoplasms - surgery | Adult | Female | Spinal Cord Neoplasms - pathology | Retrospective Studies | Spinal Cord Neoplasms - radiotherapy | Astrocytoma - mortality | Astrocytoma - surgery | Health aspects | Radiation | SURGERY | DIAGNOSIS | MULTIVARIATE ANALYSIS | PATIENTS | SPINAL CORD | ASTROCYTOMAS | BIOPSY | RADIOLOGY AND NUCLEAR MEDICINE | SYMPTOMS | RADIOTHERAPY
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14. Full Text Pathological and molecular advances in pediatric low-grade astrocytoma
by Rodriguez, Fausto J and Lim, Kah Suan and Bowers, Daniel and Eberhart, Charles G
Annual Review of Pathology: Mechanisms of Disease, ISSN 1553-4006, 2013, Volume 8, Issue 1, pp. 361 - 379
Pediatric low-grade astrocytomas are the most common brain tumors in children. They can have similar microscopic and clinical features, making accurate... 
NF1 | BRAF | RAF1 | Pilocytic astrocytoma | MAPK PATHWAY ACTIVATION | TELOMERE MAINTENANCE | pilocytic astrocytoma | PATHOLOGY | ONCOGENE-INDUCED SENESCENCE | NOONAN-SYNDROME | FORMING GLIONEURONAL TUMOR | BRAF FUSION GENE | SPORADIC PILOCYTIC ASTROCYTOMAS | GIANT-CELL ASTROCYTOMA | TUBEROUS SCLEROSIS | HUMAN CANCER | Astrocytoma - genetics | Astrocytoma - metabolism | Astrocytoma - pathology | Animals | Neoplasm Grading | Humans | Brain Neoplasms - pathology | Brain Neoplasms - therapy | Brain Neoplasms - genetics | Brain Neoplasms - metabolism | Physiology, Pathological | Physiological aspects | Molecular dynamics | Research | Children | Astrocytoma | Diseases
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