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EMBO Journal, ISSN 0261-4189, 07/2012, Volume 31, Issue 14, pp. 3038 - 3062
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 05/2014, Volume 460, pp. 127 - 139
We have previously reported that the Parkinson's disease-associated kinase PINK1 (PTEN-induced putative kinase 1) is activated by mitochondrial depolarization... 
DOMAIN | Parkinson's disease | PROTEOME | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PTEN (phosphatase and tensin homologue deleted on chromosome | ubiquitin | 10)-induced putative kinase 1 (PINK1 | PINK1 | GENE | RING | DISEASE | MUTATIONS | PROTEINS | phosphorylation | DROSOPHILA-PINK1 | Parkin
Journal Article
Genes and Development, ISSN 0890-9369, 2015, Volume 29, Issue 10, pp. 989 - 999
In this review, Durcan and Fon discuss how post-translational modifications are at the heart of how PARKIN and PINK1 function in mitochondrial quality control.... 
Ubiquitin | PARKIN | Phosphorylation | PINK1 | Mitophagy | Deubiquitination | mitophagy | deubiquitination | Review | phosphorylation | ubiquitin
Journal Article
Open Biology, ISSN 2046-2441, 2012, Volume 2, Issue MAY, pp. 120080 - 120080
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 01/2016, Volume 136, Issue 2, pp. 388 - 402
Damaged mitochondria are degraded by the autophagy–lysosome pathway and is termed mitophagy. Following mitophagy induction, the transcription factors Nrf2 and... 
TFEB | mitophagy | lysosomes | Parkinson's disease | PINK | Nrf2 | PINK1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | P62/SQSTM1 | QUALITY-CONTROL | AUTOPHAGY | NEUROSCIENCES | PARKIN | GLUCOCEREBROSIDASE | GENE | MOUSE MODEL | MUTATIONS | DROSOPHILA-PINK1 | Protein Kinases - metabolism | Sequestosome-1 Protein | Humans | Cytosol - drug effects | Mitochondrial Degradation - genetics | Heat-Shock Proteins - genetics | Tubulin - metabolism | Lysosomes - metabolism | Transfection | Time Factors | Carbonyl Cyanide m-Chlorophenyl Hydrazone - pharmacology | Cell Nucleolus - metabolism | Cell Nucleolus - drug effects | Proton Ionophores - pharmacology | Membrane Transport Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Neuroblastoma - pathology | Lysosomes - drug effects | Heat-Shock Proteins - metabolism | RNA, Small Interfering - pharmacology | Ubiquitin-Protein Ligases - metabolism | Receptors, Cell Surface - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Gene Expression Regulation - drug effects | Neuroblastoma - ultrastructure | Mitochondrial Degradation - drug effects | Cell Line, Tumor | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Cytosol - metabolism | Ubiquitin | Biosynthesis | Mitochondrial DNA | RNA | Protein binding | Proteins | Mitochondria | Transcription factors | Autophagy | Index Medicus | ORIGINAL ARTICLES | Original
Journal Article
Journal Article
AMERICAN JOURNAL OF HUMAN GENETICS, ISSN 0002-9297, 03/2016, Volume 98, Issue 3, pp. 500 - 513
Autosomal-recessive early-onset parkinsonism is clinically and genetically heterogeneous. The genetic causes of approximately 50% of autosomal-recessive... 
CLEARANCE | PINK1 | PROTEIN | INTERACT | GENE | DISEASE | GENETICS & HEREDITY | NITRIC-OXIDE | MUTATIONS | SEQUENCING DATA | ASSOCIATION
Journal Article
Autophagy, ISSN 1554-8627, 10/2019, Volume 15, Issue 10, pp. 1845 - 1847
Removal of damaged mitochondria is vital for cellular homeostasis especially in non-dividing cells, like neurons. Damaged mitochondria that cannot be repaired... 
'eat me' signal | mitophagy | PINK1/Parkin | Atg8 | SLRs | NIPSNAP1 | NIPSNAP2 | PINK1 | "eat me' signal | Parkin | CELL BIOLOGY | Index Medicus
Journal Article
Autophagy, ISSN 1554-8627, 03/2019, Volume 15, Issue 3, pp. 510 - 526
Cigarette smoke (CS)-induced accumulation of mitochondrial damage has been widely implicated in chronic obstructive pulmonary disease (COPD) pathogenesis.... 
PRKN | mitophagy | PINK1 | Cellular senescence | COPD | FIBROSIS | APOPTOSIS | MITOCHONDRIAL | PIRFENIDONE | CELL BIOLOGY | MUTATIONS | STRESS | DROSOPHILA-PINK1 | PROMOTES | PARKINSONS-DISEASE
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2010, Volume 107, Issue 1, pp. 378 - 383
Journal Article
Journal Article