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pitx1 (98) 98
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Bone, ISSN 8756-3282, 02/2020, Volume 131, p. 115177
To explore the role of low expression of Pitx1 in degenerative cartilage tissue. A cartilage injury model was established by using the cartilage scratch... 
Senescence | Sirt1 | Pitx1 | Osteoarthritis
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 10/2019, Volume 120, Issue 10, pp. 16495 - 16502
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2019, Volume 863, p. 172643
As the most fatal disease in human central nerve system, glioblastoma has attracted increasing attention. Unfortunately, the prognosis for patients with... 
miR-379–5p | MAP3K2 | circ-PITX1 | Glioblastoma | PHARMACOLOGY & PHARMACY | miR-379-5p | CANCER
Journal Article
Oncotarget, ISSN 1949-2553, 01/2018, Volume 9, Issue 7, pp. 7590 - 7603
This study assessed the interaction between physical activity and colorectal cancer (CRC) risk based on a polymorphism in the paired-like homeodomain 1 ( )... 
Physical activity | PITX1 | Interaction | Colorectal cancer | Genetic polymorphism
Journal Article
Cellular Signalling, ISSN 0898-6568, 10/2019, Volume 62, p. 109352
Gastric cancer (GC) is a common malignancy around the world. Irregular expression of microRNAs (miRNAs) contributes to the progression of malignancies. Our... 
miR-675 | PITX1 | Gastric cancer | EMT | Invasion | MIGRATION | SUPPRESSOR | METASTASIS | CELL BIOLOGY | CARCINOGENESIS | PATHWAY | MIRNA | EXPRESSION
Journal Article
Development (Cambridge, England), ISSN 0950-1991, 03/2018, Volume 145, Issue 6, pp. dev159830 - dev159830
In tetrapods, , and Hox cluster genes are crucial for forelimb and hindlimb development and mutations in these genes are responsible for congenital limb... 
Hoxc10 | Hoxa13 | Hoxd13 | ChIPseq | Pitx1 | Tbx5 | Limb specification | Tbx4 | Regulatory network | Transcription factors | Genomes | Mutation | Buds | Deoxyribonucleic acid--DNA
Journal Article
Developmental Biology, ISSN 0012-1606, 10/2019, Volume 454, Issue 2, pp. 128 - 144
The tetrapod limb is a stunning example of evolutionary diversity, with dramatic variation not only among distantly related species, but also between the... 
PELVIC REDUCTION | EVOLUTION | REGULATORY NETWORKS | DEVELOPMENTAL BIOLOGY | T-BOX GENES | HOMEOBOX GENE | PITX1 | TBX4 | EXPRESSION | MOUSE LIMB | HINDLIMB | DNA binding proteins | Gene expression | Developmental biology | Analysis | Genes
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 03/2017, Volume 140, Issue 6, pp. 1413 - 1424
Breast cancer is one of the leading causes of cancer death in women. It is a complex and heterogeneous disease with different clinical outcomes. Stratifying... 
SURVIVAL | CELLS | Gene Expression | TAMOXIFEN | TRANSCRIPTION | RECEPTOR | RISK | ALPHA | Breast cancer | ONCOLOGY | Signature | RECURRENCE | Yin Yang | BINDING | PITX1
Journal Article
Journal Article
AGING-US, ISSN 1945-4589, 10/2019, Volume 11, Issue 20, pp. 8736 - 8738
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2013, Volume 45, Issue 2, pp. 191 - 196
Journal Article
Cell Stem Cell, ISSN 1934-5909, 03/2019, Volume 24, Issue 3, pp. 390 - 404.e8
Basal tumor propagating cells (TPCs) control squamous cell carcinoma (SCC) growth by self-renewing and differentiating into supra-basal SCC cells, which lack... 
SOX2 | differentiation | cancer stem cell | transcriptional network | TRP63 | Klf4 | self-renewal | PITX1 | squamous cell carcinoma | STEM-CELLS | TGF-BETA | CHROMATIN | HAIR FOLLICLE | GENE-EXPRESSION | PROPAGATING CELLS | P63 | SEQ | TUMOR INITIATION | WOUND REPAIR | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 04/2019, Volume 56, Issue 4, pp. 246 - 251
Background Structural variants (SVs) affecting non-coding cis-regulatory elements are a common cause of congenital limb malformation. Yet, the functional... 
non coding mutations | cnvs | liebenberg | pitx1 | TRANSFORMATION | UPSTREAM | CRISPR/CAS | GENETICS & HEREDITY | CRISPR | Transformation | Gene regulation | Genes | Transgenic mice | Genomes | Regulatory sequences | Family medical history | Gene deletion | Promoters | Morphogenesis | Pathogenicity | Clonal deletion | Morphology | Stem cells | Deoxyribonucleic acid--DNA
Journal Article
General and Comparative Endocrinology, ISSN 0016-6480, 12/2019, Volume 284, p. 113263
Corticotropin-releasing hormone (CRH) is known to act as a potent thyrotropin-releasing factor in non-mammalian species such as chicken and bullfrog. This... 
Promoter | GATA-binding protein 2 (GATA2) | Corticotropin-releasing hormone (CRH) | Paired-like homeodomain 1 (PITX1) | Pituitary-specific positive transcription factor 1 (POU1F1, PIT1) | Steroidogenic factor 1 (NR5A1, SF1)
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2018, Volume 50, Issue 10, pp. 1463 - 1473
Journal Article