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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 43, pp. 18398 - 18403
Journal Article
RNA, ISSN 1355-8382, 10/2013, Volume 19, Issue 10, pp. 1405 - 1418
PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) protect genome integrity by silencing transposons in animal germlines. The molecular... 
BmPAPI | TUDOR | Mitochondria | PiRNA | PIWI | Arginine methylation | NUAGE FORMATION | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBCELLULAR-LOCALIZATION | 3' TERMINI | SPLICEOSOMAL SM PROTEINS | DROSOPHILA | PIWI-INTERACTING RNAS | TUDOR-DOMAIN | ROYAL FAMILY | arginine methylation | STRUCTURAL BASIS | piRNA | Surface Plasmon Resonance | RNA, Small Interfering - genetics | Immunoprecipitation | RNA-Induced Silencing Complex - genetics | DNA Primers - genetics | Mitochondrial Proteins - genetics | DNA Primers - chemistry | Drosophila Proteins - metabolism | Ovary - cytology | Drosophila melanogaster - genetics | Arginine - analogs & derivatives | Drosophila melanogaster - metabolism | RNA, Small Interfering - chemistry | Bombyx - metabolism | Mitochondria - genetics | Membrane Transport Proteins - genetics | Mitochondrial Proteins - metabolism | DNA Primers - metabolism | Female | Membrane Transport Proteins - metabolism | Real-Time Polymerase Chain Reaction | Ovary - metabolism | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Argonaute Proteins - metabolism | Argonaute Proteins - genetics | RNA, Messenger - genetics | Mitochondria - metabolism | Recombinant Proteins - genetics | Bombyx - genetics | Germ Cells | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Carrier Proteins - genetics | Blotting, Northern | Animals | Carrier Proteins - metabolism | Fluorescent Antibody Technique | RNA-Induced Silencing Complex - metabolism | Drosophila Proteins - genetics | Arginine - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Genomes
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2011, Volume 44, Issue 4, pp. 572 - 584
piRNAs guide PIWI proteins to silence transposons in animal germ cells. Reciprocal cycles of piRNA-directed RNA cleavage—catalyzed by the PIWI proteins... 
FEMALE STERILE MUTATIONS | SMALL RNAS | Y-CHROMOSOME | SELFISH GENETIC ELEMENTS | DROSOPHILA-MELANOGASTER | BIOCHEMISTRY & MOLECULAR BIOLOGY | EMBRYONIC AXIS SPECIFICATION | MEIOTIC CHECKPOINT | PIWI PROTEINS | ARGININE METHYLATION | 2ND CHROMOSOME | CELL BIOLOGY | RNA, Small Interfering - genetics | RNA-Induced Silencing Complex - genetics | Drosophila Proteins - metabolism | Ovary - cytology | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Oocytes - cytology | Cell Nucleus - metabolism | Fertility | Membrane Transport Proteins - genetics | DNA Transposable Elements - genetics | Female | Genome, Insect | Ovary - metabolism | Argonaute Proteins - metabolism | Argonaute Proteins - genetics | Signal Transduction | Oocytes - metabolism | Computational Biology | Ubiquitin-Protein Ligases - metabolism | RNA Cleavage | Protein Structure, Tertiary - genetics | Drosophila Proteins - chemistry | Ubiquitin-Protein Ligases - chemistry | Membrane Transport Proteins - chemistry | Peptide Initiation Factors - metabolism | Peptide Initiation Factors - genetics | Animals | Cell Nucleus - genetics | RNA-Induced Silencing Complex - metabolism | DNA Damage | Drosophila Proteins - genetics | Mutation | Ubiquitin-Protein Ligases - genetics | Gene Silencing - physiology | RNA, Small Interfering - metabolism | Medical colleges | Transposons | RNA | Ligases | Nurses | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2010, Volume 285, Issue 11, pp. 8148 - 8154
Journal Article
Development, ISSN 0950-1991, 05/2011, Volume 138, Issue 9, pp. 1863 - 1873
The nuage is a germline-specific perinuclear structure that remains functionally elusive. Recently, the nuage in Drosophila was shown to contain two of the... 
Nuage | Transposon silencing | AGO3 | TDRD | Drosophila | Partner of PIWI | SMALL RNAS | RETROTRANSPOSON | DROSOPHILA-GERMLINE | DEVELOPMENTAL BIOLOGY | GERMLINE STEM-CELLS | P-BODIES | SELFISH GENETIC ELEMENTS | PIRNA PATHWAY | PIWI PROTEINS | ARGININE METHYLATION | MELANOGASTER | RNA-Binding Proteins - genetics | Ribonucleoproteins - physiology | Male | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | DEAD-box RNA Helicases - physiology | Drosophila Proteins - physiology | DNA Transposable Elements - physiology | Gene Expression Regulation, Developmental | DNA Transposable Elements - genetics | Female | Ribonucleoproteins - genetics | Germ Cells - metabolism | DEAD-box RNA Helicases - metabolism | Carrier Proteins - physiology | RNA-Binding Proteins - physiology | Animals, Genetically Modified | Germ Cells - ultrastructure | Ribonucleoproteins - metabolism | Mutagenesis, Insertional - genetics | Peptide Initiation Factors - metabolism | Carrier Proteins - genetics | DEAD-box RNA Helicases - genetics | Peptide Initiation Factors - genetics | Animals | Carrier Proteins - metabolism | Models, Biological | Embryo, Nonmammalian | RNA-Induced Silencing Complex - metabolism | Argonaute Proteins | Protein Binding | Drosophila Proteins - genetics | Gene Silencing - physiology | RNA-Binding Proteins - metabolism | Peptide Initiation Factors - physiology | Index Medicus
Journal Article
Science, ISSN 0036-8075, 1/2004, Volume 303, Issue 5658, pp. 669 - 672
Genes normally resident in euchromatic domains are silenced when packaged into heterochromatin, as exemplified in Drosophila melanogaster by position effect... 
Heterochromatin | Eggplants | Genes | Drosophila | Alleles | Histones | Antibodies | Reports | Transgenes | Genetic mutation | Chromosomes | DOUBLE-STRANDED-RNA | GENE | CHROMATIN | DNA | MULTIDISCIPLINARY SCIENCES | PROTEIN-1 BINDS | HISTONE METHYLATION | MELANOGASTER | REPEATS | Drosophila Proteins - metabolism | ATP-Binding Cassette Transporters - physiology | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Drosophila Proteins - physiology | ATP-Binding Cassette Transporters - genetics | Heterochromatin - metabolism | RNA Interference | Eye Proteins - genetics | RNA-Induced Silencing Complex | Genes, Insect | Proteins - physiology | Histone-Lysine N-Methyltransferase - genetics | Chromosomal Proteins, Non-Histone - metabolism | Gene Silencing | Chromosomal Proteins, Non-Histone - genetics | Proteins - genetics | Animals | Histone-Lysine N-Methyltransferase - metabolism | Argonaute Proteins | Adenosine Triphosphatases - genetics | Eye Proteins - physiology | Drosophila Proteins - genetics | Histones - metabolism | Mutation | Methylation | Adenosine Triphosphatases - physiology | Insects | Ribonucleic acid--RNA | homeless gene | HP2 protein | HP1 protein | white gene | spindle-E gene | aubergine gene | position effect variegation | piwi gene | H3 lysine 9 methyltransferase | mini-white gene | Index Medicus
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 09/2017, Volume 45, Issue 15, pp. 9149 - 9163
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 13, pp. 3374 - 3379
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2017, Volume 36, Issue 21, pp. 3194 - 3211
PIWI proteins play essential roles in germ cells and stem cell lineages. In Drosophila , Piwi is required in somatic niche cells and germline stem cells ( GSC... 
NOT | CCR | germline stem cells | RNA | proteins | translational control | deadenylation complex | PIWI | CCR4-NOT deadenylation complex | piRNAs | PIWI proteins | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | EMBRYONIC AXIS SPECIFICATION | EARLY DROSOPHILA EMBRYO | UBIQUITIN LIGASES | PIWI-INTERACTING RNAS | CELL BIOLOGY | MESSENGER-RNA DEADENYLATION | PATHWAY | CCR4-NOT COMPLEX | TUMOR-SUPPRESSOR | DIFFERENTIATION | RNA, Small Interfering - genetics | Proto-Oncogene Proteins c-cbl - metabolism | Ribonucleases - genetics | Stem Cells - cytology | Drosophila Proteins - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Drosophila melanogaster - genetics | Ribonucleases - metabolism | Drosophila melanogaster - metabolism | Gene Expression Regulation, Developmental | Base Sequence | Cell Differentiation | Germ Cells - metabolism | Cell Lineage - genetics | Proto-Oncogene Proteins c-cbl - genetics | Argonaute Proteins - metabolism | Argonaute Proteins - genetics | RNA, Messenger - genetics | Germ Cells - growth & development | Peptide Initiation Factors - metabolism | Carrier Proteins - genetics | Peptide Initiation Factors - genetics | Animals | Carrier Proteins - metabolism | Embryo, Nonmammalian | Drosophila melanogaster - growth & development | Drosophila Proteins - genetics | RNA, Small Interfering - metabolism | Cbl protein | Repressing | Post-transcription | Translation | Regulators | Germ cells | Transcription | Drosophila | Homeostasis | Recruitment | Proteins | Insects | Stem cells | Aberration | Differentiation | Index Medicus | Life Sciences | Genetics | CCR4‐NOT deadenylation complex | Stem Cells | Development & Differentiation | RNA Biology
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2016, Volume 61, Issue 1, pp. 138 - 152
Journal Article
Nature, ISSN 0028-0836, 10/2010, Volume 467, Issue 7319, pp. 1128 - 1132
Piwi-associated RNAs (piRNAs), a specific class of 24- to 30-nucleotide-long RNAs produced by the Piwi-type of Argonaute proteins, have a specific germline... 
LOCALIZATION | TRANSLATIONAL REGULATION | GERMLINE | ACTIVATION | NANOS | MULTIDISCIPLINARY SCIENCES | BINDING-PROTEIN | MUTATIONS | MELANOGASTER | PIWI | AXIS SPECIFICATION | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Drosophila melanogaster - embryology | Embryo, Nonmammalian - cytology | Ribonucleases - genetics | Embryo, Nonmammalian - metabolism | Zygote - metabolism | 3' Untranslated Regions - genetics | Cytoplasm - metabolism | Embryo, Nonmammalian - embryology | Drosophila Proteins - metabolism | RNA, Messenger - metabolism | Drosophila melanogaster - genetics | Mothers | Ribonucleases - metabolism | Gene Expression Regulation, Developmental | DNA Transposable Elements - genetics | Female | Cytoplasm - genetics | Repressor Proteins - metabolism | RNA, Messenger - genetics | Drosophila melanogaster - cytology | Repressor Proteins - genetics | RNA Stability | Peptide Initiation Factors - metabolism | Peptide Initiation Factors - genetics | Polyadenylation - genetics | Animals | Argonaute Proteins | Drosophila Proteins - genetics | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Embryonic development | Messenger RNA | Drosophila | Genetic aspects | Research | Gene expression | Properties | Proteins | Signal transduction | Cytoplasm | Index Medicus | CCR4 deadenylase | RNA silencing | nanos | Translational control | piRNA | mRNA decay
Journal Article
Cellular Microbiology, ISSN 1462-5814, 06/2012, Volume 14, Issue 6, pp. 882 - 901
Journal Article