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1. Full Text The Chlamydia M278 Major outer membrane peptide encapsulated in the poly(lactic acid)-poly(ethylene glycol) nanoparticulate self-adjuvanting delivery system protects mice against a Chlamydia muridarumgenital tract challenge by stimulating robust systemic and local mucosal immune responses
by Verma, Richa and Sahu, Rajnish and Dixit, Saurabh and Duncan, Skyla A and Giambartolomei, Guillermo H and Singh, Shree R and Dennis, Vida A
Frontiers in Immunology, 10/2018, Volume 9
IFN-γ | Nanovaccine | Chlamydia | Mucosal IgA | Neutralizing antibodies | PLA-PEG nanoparticles
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2. Full Text Polylactide/poly(ethylene glycol)/polylactide triblock copolymer micelles as carrier for delivery of hydrophilic and hydrophobic drugs: a comparison study
by Danafar, H and Rostamizadeh, K and Hamidi, M
Journal of Pharmaceutical Investigation, ISSN 2093-5552, 05/2018, Volume 48, Issue 3, pp. 381 - 391
Tri-block poly(lactide)–poly(ethylene glycol)– poly(lactide) (PLA–PEG–PLA) copolymers were synthesized and self-assembled into micelles in aqueous solution by... 
PLA–PEG–PLA | Atorvastatin | Lisinopril | Hydrophobic drugs | Micelles | Hydrophilic drugs
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3. Full Text In situ mucoadhesive-thermosensitive liposomal gel as a novel vehicle for nasal extended delivery of opiorphin
by Mura, Paola and Mennini, Natascia and Nativi, Cristina and Richichi, Barbara
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 01/2018, Volume 122, pp. 54 - 61
Previous studies proved the effectiveness of an intravenous PEGylated liposomal formulation of opiorphin (1 mg/mL) in protecting the drug from enzymatic... 
Ex vivo permeation | PEGylated liposomes | In situ nasal delivery | Mucoadhesion | Opiorphin | Thermosensitive hydrogel | DESIGN | HYDROGELS | DRUG-DELIVERY | TOLERANCE | FORMULATION | PEPTIDE | POLOXAMER | TEMPERATURE | PLA-PEG PARTICLES | PHARMACOLOGY & PHARMACY | OPTIMIZATION | Peptides | Enzymes | Permeability
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4. Full Text Core–Shell Structure, Biodegradation, and Drug Release Behavior of Poly(lactic acid)/Poly(ethylene glycol) Block Copolymer Micelles Tuned by Macromolecular Stereostructure
by Ma, Chenlei and Pan, Pengju and Shan, Guorong and Bao, Yongzhong and Fujita, Masahiro and Maeda, Mizuo
Langmuir, ISSN 0743-7463, 02/2015, Volume 31, Issue 4, pp. 1527 - 1536
Poly­(ethylene glycol)-b-poly­(l-lactic acid)-b-poly­(d-lactic acid) (PEG-b-PLLA-b-PDLA) stereoblock copolymers were synthesized by sequential ring-opening... 
PLA-PEG NANOPARTICLES | REACTIVE POLYMERIC MICELLE | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | STEREOCOMPLEX FORMATION | CHEMISTRY, MULTIDISCIPLINARY | AQUEOUS-SOLUTION | DELIVERY | MICELLIZATION | DIBLOCK | DEGRADATION | MICROGELS | SCATTERING | Polyesters - chemistry | Macromolecular Substances - chemistry | Proton Magnetic Resonance Spectroscopy | Micelles | Calorimetry, Differential Scanning | Polyethylene Glycols - chemistry | Molecular Structure | Scattering, Radiation
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5. Full Text Smart Polymeric Hydrogels for Cartilage Tissue Engineering: A Review on the Chemistry and Biological Functions
by Eslahi, Niloofar and Abdorahim, Marjan and Simchi, Abdolreza
Biomacromolecules, ISSN 1525-7797, 11/2016, Volume 17, Issue 11, pp. 3441 - 3463
Stimuli responsive hydrogels (SRHs) are attractive bioscaffolds for tissue engineering. The structural similarity of SRHs to the extracellular matrix (ECM) of... 
CATIONIC COPOLYMER HYDROGELS | POLYMER SCIENCE | INJECTABLE SUPRAMOLECULAR HYDROGELS | DRUG-DELIVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYALURONIC-ACID HYDROGELS | CHEMISTRY, ORGANIC | PLA-PEG-PLA | MESENCHYMAL STEM-CELLS | KERATIN-BASED BIOMATERIALS | SITU-FORMING HYDROGELS | HUMAN HAIR KERATIN | ARTICULAR-CARTILAGE | Cartilage - growth & development | Biocompatible Materials - chemistry | Extracellular Matrix - drug effects | Humans | Cartilage - drug effects | Tissue Scaffolds - chemistry | Polymers - therapeutic use | Regeneration - drug effects | Nanostructures - chemistry | Polymers - chemistry | Biocompatible Materials - therapeutic use | Hydrogels - therapeutic use | Wound Healing - drug effects | Hydrogels - chemistry | Nanostructures - therapeutic use | Tissue Engineering
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6. Full Text Mesoscopic Structures of Poly(carboxybetaine) Block Copolymer and Poly(ethylene glycol) Block Copolymer in Solutions
by Liao, Mingrui and Liu, Hongyan and Guo, Hongyu and Zhou, Jian
Langmuir, ISSN 0743-7463, 08/2017, Volume 33, Issue 30, pp. 7575 - 7582
The antifouling property of exogenous materials is vital for their in vivo applications. In this work, dissipative particle dynamics simulations are performed... 
PLA-PEG NANOPARTICLES | DISSIPATIVE PARTICLE DYNAMICS | HYDROGELS | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | PROTEIN RESISTANCE | CHEMISTRY, PHYSICAL | CHEMISTRY, MULTIDISCIPLINARY | HYDRATION | ZWITTERIONIC SURFACE | POLYMER | COMPUTER-SIMULATIONS | PLGA MICROSPHERES
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7. Full Text Influence of process and formulation parameters on the formation of submicron particles by solvent displacement and emulsification-diffusion methods: Critical comparison
by Mora-Huertas, C.E and Fessi, H and Elaissari, A
Advances in Colloid and Interface Science, ISSN 0001-8686, 04/2011, Volume 163, Issue 2, pp. 90 - 122
Solvent displacement and emulsification-diffusion are the methods used most often for preparing biodegradable submicron particles. The major difference between... 
Nanoparticles | Solvent displacement | Particle size | Nanoprecipitation | Zeta-potential | Emulsification-diffusion | Submicron particle | PLA-PEG NANOPARTICLES | DRUG-DELIVERY | CHEMISTRY, PHYSICAL | LOADED PLGA NANOPARTICLES | TRANS-RETINOIC ACID | BIODEGRADABLE NANOPARTICLES | POLY(D,L-LACTIC ACID) NANOPARTICLES | EPSILON-CAPROLACTONE NANOPARTICLES | POLYMERIC NANOPARTICLES | ORAL DELIVERY | BEHAVIOR IN-VITRO | Formulations | Design engineering | Solvents | Biodegradability | Raw materials | Criteria | Polymers | Displacement
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8. Full Text Poly(lactic acid) based hydrogels
by Basu, Arijit and Kunduru, Konda Reddy and Doppalapudi, Sindhu and Domb, Abraham J and Khan, Wahid
Advanced Drug Delivery Reviews, ISSN 0169-409X, 12/2016, Volume 107, pp. 192 - 205
Polylactide (PLA) and its copolymers are hydrophobic polyesters used for biomedical applications. Hydrogel medicinal implants have been used as drug delivery... 
In situ hydrogel | PLA–PEG | Responsive polymer | Hydrogel | PLA | Thermo-responsive | THERMOSENSITIVE HYDROGEL | PLA-PEG | SOL-GEL TRANSITION | STEREOCOMPLEX FORMATION | INJECTABLE HYDROGELS | IN-VITRO | BIODEGRADABLE BLOCK-COPOLYMERS | POLY(ETHYLENE GLYCOL) | PHARMACOLOGY & PHARMACY | BIOMEDICAL APPLICATIONS | PEG TRIBLOCK COPOLYMERS | DRUG-DELIVERY SYSTEMS | Drugs | Ethylene glycol | Drug delivery systems | Crosslinked polymers | Tissue engineering | Lactic acid | Chemical properties | Vehicles | Usage | Jewish schools | Aspartate | Permeability | Transforming growth factors | Glycine | Polyurethanes | Polysaccharides | Methylcellulose | Pharmacy | Bone morphogenetic proteins | Ethylene oxide | Carbonates
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9. Full Text Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus
by Xu, Qingguo and Boylan, Nicholas J and Cai, Shutian and Miao, Bolong and Patel, Himatkumar and Hanes, Justin
Journal of Controlled Release, ISSN 0168-3659, 09/2013, Volume 170, Issue 2, pp. 279 - 286
Mucus typically traps and rapidly removes foreign particles from the airways, gastrointestinal tract, nasopharynx, female reproductive tract and the surface of... 
Drug delivery | Surface PEG density | Mucus-penetrating particles | Emulsification | Nanomedicine | DRUG | THERAPEUTICS | PLA-PEG NANOPARTICLES | VIVO | ENCAPSULATION | POLY(D,L-LACTIDE-CO-GLYCOLIDE) | CHEMISTRY, MULTIDISCIPLINARY | OF-THE-ART | TRIGGERED RELEASE | TRANSPORT | PHARMACOLOGY & PHARMACY | MICROENCAPSULATION | Polyvinyl Alcohol - chemistry | Nanoparticles - chemistry | Curcumin - chemistry | Humans | Drug Compounding | Female | Polyethylene Glycols - chemistry | Mucus - chemistry | Permeability | Polyglactin 910 - chemistry | Drug Delivery Systems | Nanoparticles | Drugs | Drug delivery systems | Analysis | Gastrointestinal system | Polyols | Methods | Vehicles | Biodegradability
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10. Full Text Development of a nanostructured DNA delivery scaffold via electrospinning of PLGA and PLA–PEG block copolymers
by Luu, Y.K and Kim, K and Hsiao, B.S and Chu, B and Hadjiargyrou, M
Journal of Controlled Release, ISSN 0168-3659, 2003, Volume 89, Issue 2, pp. 341 - 353
The present work utilizes electrospinning to fabricate synthetic polymer/DNA composite scaffolds for therapeutic application in gene delivery for tissue... 
Electrospinning | Gene delivery | PLGA | PLA–PEG block copolymer | Tissue engineering | Life Sciences (General) | PLA-PEG block copolymer | tissue engineering | TISSUE ENGINEERING SCAFFOLDS | TRANSFECTION | COMPLEXES | ENCAPSULATION | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | gene delivery | electrospinning | PLASMID DNA | IN-VIVO | POLYMER | PHARMACOLOGY & PHARMACY | DIFFERENTIATION | Cell Line | Polymers - administration & dosage | Nanotechnology - methods | DNA - administration & dosage | Polyethylene Glycols - administration & dosage | DNA - genetics | Animals | Lactates - administration & dosage | Transfection - methods | Mice | Drug Delivery Systems - methods | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage
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11. Full Text Building the design, translation and development principles of polymeric nanomedicines using the case of clinically advanced poly(lactide(glycolide))–poly(ethylene glycol) nanotechnology as a model: An industrial viewpoint
by Lakkireddy, Harivardhan Reddy and Bazile, Didier
Advanced Drug Delivery Reviews, ISSN 0169-409X, 12/2016, Volume 107, pp. 289 - 332
The design of the first polymeric nanoparticles could be traced back to the 1970s, and has thereafter received considerable attention, as evidenced by the... 
Polyester | Translation | Chemistry | Pharmaceutical development | Polylactide | Polyethylene glycol | Nanoparticle | Manufacturing and Control | PLA-PEG NANOPARTICLES | ETHYLENE OXIDE) NANOPARTICLES | PLA/PEO/PLA TRIBLOCK COPOLYMERS | DIFFERENT MOLECULAR-WEIGHTS | BLOCK-COPOLYMER MICELLES | BLOOD-BRAIN-BARRIER | PLGA-BASED NANOPARTICLES | LOADED BIODEGRADABLE NANOSPHERES | PROTEIN SURFACE INTERACTIONS | PHARMACOLOGY & PHARMACY | RING-OPENING POLYMERIZATION
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12. Full Text "Clickable" polylactic acids obtained by solvent free intra-chain amidation
by Scala, A and Piperno, A and Torcasio, SM and Nicosia, A and Mineo, PG and Grassi, G
EUROPEAN POLYMER JOURNAL, ISSN 0014-3057, 12/2018, Volume 109, pp. 341 - 346
An innovative solvent- and catalyst-free procedure for the grafting of acetylene groups on polylactic acid (PLA) backbone is reported, using propargylamine as... 
Rhodamine | POLYMER SCIENCE | MOLECULAR-WEIGHT | Propargylamine | PLA-PEG | Pent-4-ynoic anhydride | AMPHIPHILIC GRAFT-COPOLYMERS | POLYDISPERSE POLYMERS | TIME | POLYMERIZATION | BLENDS | NANOPARTICLES | MASS | Click chemistry | Hydroxides | Chemical tests and reagents | Biopolymers | Analysis | Acetylene
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13. Full Text Bioresorbable filomicelles for targeted delivery of betulin derivative – In vitro study
by Jelonek, Katarzyna and Kasperczyk, Janusz and Li, Suming and Nguyen, Thi Hong Nhung and Orchel, Arkadiusz and Chodurek, Ewa and Paduszyński, Piotr and Jaworska-Kik, Marzena and Chrobak, Elwira and Bębenek, Ewa and Boryczka, Stanisław and Jarosz-Biej, Magdalena and Smolarczyk, Ryszard and Foryś, Aleksander
International Journal of Pharmaceutics, ISSN 0378-5173, 02/2019, Volume 557, pp. 43 - 52
Filomicelles (worm-like micelles) possess high drug loading capacity and long circulation time in the bloodstream. A novel approach can be filomicelles with... 
Betulin derivative | Filomicelles | Targeted therapy | Micelles | PLA-PEG | Folic acid | DRUG | BLOCK-COPOLYMERS | BEHAVIOR | FOLATE RECEPTOR | POLYMERIZATION | RELEASE | PACLITAXEL | NANOPARTICLES | DEGRADATION | PHARMACOLOGY & PHARMACY | Polymers - administration & dosage | Triterpenes - chemistry | Apoptosis - drug effects | Humans | Folic Acid - chemistry | Polymers - chemistry | HeLa Cells | Folic Acid - administration & dosage | Triterpenes - administration & dosage | Drug Delivery Systems | Chemical Sciences
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14. Full Text Formulation and evaluation of anticancer and antiangiogenesis efficiency of PLA–PEG nanoparticles loaded with galbanic acid in C26 colon carcinoma, in vitro and in vivo
by Afsharzadeh, Maryam and Abnous, Khalil and Yazdian–Robati, Rezvan and Ataranzadeh, Armin and Ramezani, Mohammad and Hashemi, Maryam
Journal of Cellular Physiology, ISSN 0021-9541, 05/2019, Volume 234, Issue 5, pp. 6099 - 6107
Galbanic acid (GBA) is an active sesquiterpene coumarin derivative, with various medicinal benefits, including anticancer properties. However, the low... 
C26 colon carcinoma | PLA–PEG | galbanic acid | antiangiogenesis | SYSTEM | NATURAL-PRODUCT | PHYSIOLOGY | ANGIOGENESIS | CURCUMIN | PLA-PEG | DELIVERY | CELL BIOLOGY | CD34 antigen | Polyethylene | Toxicity | Therapeutic applications | Emulsification | Colorectal carcinoma | Blood vessels | Cytotoxicity | Evaporation | pH effects