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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2010, Volume 107, Issue 7, pp. 3198 - 3203
Journal Article
Toxicon, ISSN 0041-0101, 05/2011, Volume 57, Issue 6, pp. 851 - 860
In this paper was demonstrated that umbelliferone induces changes in structure and pharmacological activities of Bn IV, a lysine 49 secretory phospholipase A... 
Secretory phospholipase A | Umbelliferone | Anti-PLA2 activity | sPLA2 | Lys49 PLA2
Journal Article
Developmental & Comparative Immunology, ISSN 0145-305X, 02/2020, Volume 103, p. 103500
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 12/2018, Volume 89, pp. 83 - 92
Eicosanoids are oxygenated C20 polyunsaturated fatty acids that mediate various physiological processes in insects. Eicosanoid biosynthesis begins with a C20... 
PLA2 | Development | Eicosanoid | Immune | Spodoptera exigua | PLA
Journal Article
by Millwood, Iona Y and Millwood, Iona Y and Bennett, Derrick A and Bennett, Derrick A and Walters, Robin G and Walters, Robin G and Clarke, Robert and Clarke, Robert and Waterworth, Dawn and Waterworth, Dawn and Johnson, Toby and Johnson, Toby and Chen, Yiping and Chen, Yiping and Yang, Ling and Yang, Ling and Guo, Yu and Guo, Yu and Bian, Zheng and Bian, Zheng and Hacker, Alex and Hacker, Alex and Yeo, Astrid and Yeo, Astrid and Parish, Sarah and Parish, Sarah and Hill, Michael R and Hill, Michael R and Chissoe, Stephanie and Chissoe, Stephanie and Peto, Richard and Peto, Richard and Cardon, Lon and Cardon, Lon and Collins, Rory and Collins, Rory and Li, Liming and Li, Liming and Chen, Zhengming and Chen, Zhengming and Chen, Junshi and Avery, Daniel and Chang, Yumei and Du, Huaidong and Fan, Xuejuan and Gilbert, Simon and Holmes, Michael and Iona, Andri and Kerosi, Rene and Kong, Ling and Kurmi, Om and Lancaster, Garry and Lewington, Sarah and McDonnell, John and Mei, Winnie and Nie, Qunhua and Radhakrishnan, Jayakrishnan and Ryder, Paul and Sansome, Sam and Schmidt, Dan and Sherliker, Paul and Sohoni, Rajani and Sun, Luanlaun and Wang, Jenny and Wang, Lin and Yang, Xiaoming and Chen, Ge and Guo, Lei and Han, Bingyang and Hou, Can and Liu, Peng and Lv, Jun and Pei, Pei and Qu, Shuzhen and Tan, Yunlong and Yu, Canqing and Zhou, Huiyan and Pang, Zengchang and Wang, Shaojie and Zhang, Yun and Zhang, Kui and Liu, Silu and Hou, Wei and Zhao, Zhonghou and Liu, Shumei and Pang, Zhigang and Feng, Weijia and Wu, Shuling and Yang, Liqiu and Han, Huili and He, Hui and Yu, Bo and Pan, Xianhai and Wang, Shanqing and Wang, Hongmei and Hao, Xinhua and Chen, Chunxing and Lin, Shuxiong and Zheng, Xiangyang and Hu, Xiaoshu and ...
International journal of epidemiology, ISSN 0300-5771, 2016, Volume 45, Issue 5, pp. 1588 - 1599
Journal Article
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 07/2018, Volume 113, pp. 575 - 582
Phagocytosis, a process involved in host defense, requires coordination of a variety of signaling reactions. MT-II, a catalytically-inactive Lys49-PLA ¸ and... 
Signal transduction | Venom PLA2 | Macrophages | Phagocytosis | Venom PLA
Journal Article
Chinese Pharmaceutical Journal, ISSN 1001-2494, 02/2015, Volume 50, Issue 4, pp. 317 - 322
Journal Article
Journal of Maternal-Fetal and Neonatal Medicine, ISSN 1476-7058, 2019, pp. 1 - 9
The study tested whether cardiovascular corresponding LPA risk genotypes improve pre-eclampsia and coronary heart disease (CHD) risk prediction beyond... 
LPA SNP | preeclampsia | inflammation | CV risk | Lp-PLA2
Journal Article
Journal of Invertebrate Pathology, ISSN 0022-2011, 10/2017, Volume 149, pp. 97 - 105
Phospholipase A (PLA ) hydrolyzes ester bond of phospholipids at the position to release free fatty acid and lysophospholipids. Some PLA s preferentially... 
Oxindole | Eicosanoids | PLA2 | Xenorhabdus hominickii | Spodoptera exigua | PLA
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 12/2018, Volume 841, pp. 49 - 56
Lysophosphatidic acid receptor 1 (LPA ) is one of six G protein-coupled receptors (GPCRs) activated by the bioactive lipid, lysophosphatidic acid (LPA).... 
GPCR | Carrageenan | Phospholipase A2 (PLA2) | Lysophosphatidic acid (LPA) | Inflammatory pain | LPA1 | PLA | LPA | Phospholipase A
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2007, Volume 406, Issue 3, pp. 427 - 436
PLA2 (phospholipase A2) enzymes play critical roles in membrane phospholipid homoeostasis and in generation of lysophospholipid growth factors. In the present... 
Calcium-independent phospholipase A | Tumorigenesis | Lysophosphatidic acid | Growth autonomy | Ovarian cancer cell | Cell cycle | Cell Proliferation | Calcium | Humans | Phospholipases A - metabolism | Phospholipases A2 | Pyrones - pharmacology | G2 Phase - drug effects | Group VI Phospholipases A2 | Ovarian Neoplasms - genetics | Cyclins - metabolism | Lysophospholipids - pharmacology | Female | Ovarian Neoplasms - metabolism | Tumor Cells, Cultured | G2 Phase - physiology | Ovarian Neoplasms - prevention & control | RNA, Small Interfering - pharmacology | Blotting, Western | Cell Division - drug effects | Naphthalenes - pharmacology | Cell Division - physiology | Animals | Phospholipases A - genetics | Mice, Nude | Phospholipases A - antagonists & inhibitors | S Phase - physiology | Cytosol - metabolism | Mice | Mice, Inbred BALB C | S Phase - drug effects | Epidermal Growth Factor - pharmacology | Apoptosis | BEL, bromoenol lactone | HEK-293 cells, human embryonic kidney cells | GFP, green fluorescent protein | cell cycle | EGF, epidermal growth factor | PLA2, phospholipase A2 | cPLA2, cytosolic PLA2 | ovarian cancer cell | calcium-independent phospholipase A2 | LPA, lysophosphatidic acid | shRNA, small-hairpin RNA | iPLA2, calcium-independent PLA2 | lysophosphatidic acid | growth autonomy | siRNA, short interfering RNA | FBS, foetal bovine serum | tumorigenesis
Journal Article
Clinical Science, ISSN 0143-5221, 08/2013, Volume 125, Issue 3, pp. 121 - 130
Journal Article
Clinical nutrition (Edinburgh, Scotland), ISSN 0261-5614, 04/2019
Metabolically unhealthy overweight (MUO) individuals and metabolically healthy overweight (MHO) individuals differ in biomarkers of atherogenesis. Metabolomic... 
Journal Article
Toxicon, ISSN 0041-0101, 11/2016, Volume 122, pp. 160 - 166
We have shown that jellyfish venom (NnV) contains various kinds of proteolytic enzyme activities, including phospholipase (PLA), metalloproteinase (MP) and... 
Genomic DNA sequence | Nemopilema nomurai jellyfish venom | Phospholipase A2 | Acidic PLA2 PA4 | PLA2 PA3A/PA3B/PA5 | Full-length cDNA sequence | PA3A/PA3B/PA5 | PA4 | PLA | Acidic PLA | Phospholipase A | Index Medicus | Residues | Phospholipase | Cysteine | Genes | Disulfides | Amino acids | Joints | Plugs
Journal Article
Journal of Functional Foods, ISSN 1756-4646, 12/2015, Volume 19, pp. 744 - 752
The effect of consumption of two probiotic strains, HY7601 and KY1032, on weight loss, body adiposity and lipoprotein-associated phospholipase A (Lp-PLA )... 
Probiotic | DEXA | Fat mass | Lp-PLA2 | Weight loss | Lp-PLA
Journal Article
Clinical Biochemistry, ISSN 0009-9120, 12/2017, Volume 50, Issue 18, pp. 1209 - 1215
There are two platforms for the detection of Lp-PLA in sera or plasmas: by its enzymatic activity (PLAC® activity test) and by its mass concentration (PLAC®... 
HDL | Stroke | LDL | PAF-AH | Phospholipid | PLAC | Lipoprotein | Lp-PLA2 | CHD | Lp-PLA
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 1, pp. 17 - 27
PLA2 (phospholipase A2) group III is an atypical sPLA2 (secretory PLA2) that is homologous with bee venom PLA2 rather than with other mammalian sPLA2s. In the... 
Phospholipid | Splenomegaly | Transgenic mouse | Phospholipase A2 | Prostaglandin | Dermatitis | Group III Phospholipases A2 - metabolism | Dermatitis - pathology | Inflammation - metabolism | Animals | Dermatitis - genetics | Group III Phospholipases A2 - genetics | Mice, Transgenic | Mice | Gene Expression Regulation, Enzymologic - physiology | Skin - pathology | Dermatitis - metabolism | BRAK, breast- and kidney-expressed chemokine | WT, wild-type | phospholipase A2 | PGE2, prostaglandin E2 | mPGES, microsomal prostaglandin E synthase | cPLA2, cytosolic PLA2 | RT, reverse transcription | ESI, electrospray ionization | transgenic mouse | MPO, myeloperoxidase | dermatitis | MCP-1, monocyte chemoattractant protein-1 | PAF, platelet-activating factor | LDL, low-density lipoprotein | TNFα, tumour necrosis factor α | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | IFN, interferon | PC, phosphatidylcholine | sPLA2, secretory PLA2 | COX, cyclo-oxygenase | PAS, periodic acid–Schiff | prostaglandin | PLA2G2A (etc.), sPLA2 group IIA (etc.) | PLA2, phospholipase A2 | CAG, chicken β-actin | LTB4, leukotriene B4 | NK, natural killer | IL, interleukin | mMCP, mouse mast cell protease | LPS, lipopolysaccharide | HDC, histidine decarboxylase | LNL, LoxP–neomycin-resistance gene–LoxP | phospholipid | Tg, transgenic | splenomegaly | HDL, high-density lipoprotein
Journal Article
Atherosclerosis, ISSN 0021-9150, 11/2017, Volume 266, pp. 1 - 7
We performed a prospective investigation of the longer-term prognostic value of lipoprotein-associated phospholipase A (Lp-PLA ) mass for all-cause mortality... 
Lp-PLA2 mass | All-cause mortality | Prognosis | Vascular events | Acute ischemic stroke
Journal Article
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