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1. Full Text Nephrotoxicity of plasma volume expanders
by Commereuc, M and Schortgen, F
NEPHROLOGIE & THERAPEUTIQUE, ISSN 1769-7255, 12/2018, Volume 14, Issue 7, pp. 555 - 563
Expansion of extracellular volume is a treatment traditionally proposed to correct abnormalities of renal perfusion and prevent ischemic injury. However,... 
ACUTE KIDNEY INJURY | NORMAL SALINE RESUSCITATION | SODIUM-BICARBONATE | Colloids | Hydroxyethylstarch | ACUTE LUNG INJURY | ACUTE-RENAL-FAILURE | Oncotic pressure | BLOOD-FLOW | Acute renal failure | FLUID RESUSCITATION | LACTATED RINGERS SOLUTION | Remplissage | Osmotic nephrosis | UROLOGY & NEPHROLOGY | HYDROXYETHYL STARCH 130/0.4 | OSMOTIC-NEPHROSIS | Animals | Kidney Diseases - etiology | Humans | Kidney - physiopathology | Plasma Substitutes - adverse effects
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2. Full Text Volume expanders for the prevention of ovarian hyperstimulation syndrome
by Youssef, Mohamed A and Mourad, Selma
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 08/2016, Volume 2016, Issue 8, p. CD001302
Background Ovarian hyperstimulation syndrome (OHSS) is a serious and potentially fatal complication of ovarian stimulation which affects 1% to 14% of all in... 
Hydroxyethyl Starch Derivatives [administration & dosage] | INTRAVENOUS ALBUMIN | Injections, Intravenous | Humans | HYDROXYETHYL STARCH | Plasma Substitutes [administration & dosage] | Randomized Controlled Trials as Topic | OOCYTE MATURATION | Sperm Injections, Intracytoplasmic | MEDICINE, GENERAL & INTERNAL | Fertilization in Vitro | SYNDROME OHSS | HIGH-RISK | DOUBLE-BLIND | Serum Albumin [administration & dosage] | Female | IN-VITRO FERTILIZATION | GNRH AGONIST | IVF PATIENTS | Ovarian Hyperstimulation Syndrome [prevention & control] | ENDOTHELIAL GROWTH-FACTOR | Pregnancy | Hydroxyethyl Starch Derivatives - administration & dosage | Plasma Substitutes - administration & dosage | Serum Albumin - administration & dosage | Ovarian Hyperstimulation Syndrome - prevention & control | Pregnancy Rate
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3. Full Text Plasma expanders stabilize human microvessels in microfluidic scaffolds
by Leung, Alexander D and Wong, Keith H. K and Tien, Joe
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 07/2012, Volume 100A, Issue 7, pp. 1815 - 1822
Plasma expanders such as dextran and hydroxyethyl starch (HES) are important components of solutions designed to maintain vascular volume in the clinical... 
hydroxyethyl starch | dextran | microfluidic hydrogel | perfusion | microvascular tissue engineering | PHYSIOLOGY | MATERIALS SCIENCE, BIOMATERIALS | MOLECULAR-WEIGHT | PERMEABILITY | ENGINEERING, BIOMEDICAL | ORGAN PRESERVATION | CYCLIC-AMP | BLOOD-CELL AGGREGATION | PHARMACOLOGY | FABRICATION | TUBES IN-VITRO | VASCULAR ENDOTHELIAL-CADHERIN | Tissue Scaffolds | Dextrans | Humans | Hydroxyethyl Starch Derivatives | Plasma Substitutes - pharmacology | Microvessels - drug effects | Cadherins | Microfluidics | Antigens, CD | Microvascular tissue engineering
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4. Full Text Supra-Plasma Expanders: The Future of Treating Blood Loss and Anemia Without Red Cell Transfusions?
by Tsai, Amy G and Vázquez, Beatriz Y Salazar and Hofmann, Axel and Acharya, Seetharama A and Intaglietta, Marcos
Journal of Infusion Nursing, ISSN 1533-1458, 05/2015, Volume 38, Issue 3, pp. 217 - 222
Oxygen delivery capacity during profoundly anemic conditions depends on bloodʼs oxygen-carrying capacity and cardiac output. Oxygen-carrying blood substitutes... 
microvascular perfusion | blood transfusion | oxygen transport | oxygen delivery | microcirculation | hemorrhage | transfusion alternatives | Anemia - therapy | Erythrocyte Transfusion | Hemorrhage - therapy | Humans | Oxygen - blood | Plasma Substitutes - pharmacology
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5. Full Text How safe is gelatin? A systematic review and meta-analysis of gelatin-containing plasma expanders vs crystalloids and albumin
by Moeller, Claudia and Fleischmann, Carolin and Thomas-Rueddel, Daniel and Vlasakov, Vlasislav and Rochwerg, Bram and Theurer, Philip and Gattinoni, Luciano and Reinhart, Konrad and Hartog, Christiane S
Journal of Critical Care, ISSN 0883-9441, 10/2016, Volume 35, pp. 75 - 83
Gelatin is a widely used synthetic colloid resuscitation fluid. We undertook a systematic review and meta-analysis of adverse effects in randomized and... 
Renal insufficiency | Anaphylaxis | Adverse effects | Plasma substitutes | Colloids | Bleeding | ACUTE KIDNEY INJURY | HYPOVOLEMIC SHOCK | HYDROXYETHYL STARCH | MODIFIED FLUID GELATIN | RINGERS SOLUTION | INTENSIVE-CARE | CARDIAC-SURGERY | HEMOSTATIC CHANGES | CRITICALLY-ILL PATIENTS | VOLUME REPLACEMENT | CRITICAL CARE MEDICINE | Fluid Therapy | Gelatin - administration & dosage | Hospital Mortality | Gelatin - adverse effects | Humans | Isotonic Solutions - administration & dosage | Hypovolemia - mortality | Isotonic Solutions - adverse effects | Hypovolemia - therapy | Plasma Substitutes - adverse effects | Albumin | Blood transfusion | Analysis
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6. Full Text Safety of Plasma Volume Expanders
by Farrugia, Albert
The Journal of Clinical Pharmacology, ISSN 0091-2700, 03/2011, Volume 51, Issue 3, pp. 292 - 300
Hypovolemia from a range of etiologies can lead to severe morbidity and mortality unless blood volume and tissue perfusion are restored. The treatment of... 
Albumin | colloids | pharmacovigilance | safety | PREKALLIKREIN ACTIVATOR | ACUTE-RENAL-FAILURE | IN-VITRO | IMPAIR HEMOSTASIS | HUMAN-ALBUMIN | PHARMACOLOGY & PHARMACY | INCREASE BLOOD-LOSS | CREUTZFELDT-JAKOB-DISEASE | HYDROXYETHYL STARCH 130/0.4 | ELDERLY-PATIENTS | TRANSFUSION REQUIREMENTS | Plasma Substitutes - therapeutic use | Hypovolemia - drug therapy | Colloids | Glycoproteins - therapeutic use | Humans | Glycoproteins - adverse effects | Serum Albumin, Human | Serum Albumin - adverse effects | Serum Albumin - therapeutic use | Blood Coagulation Disorders - drug therapy | Animals | Renal Insufficiency - physiopathology | Renal Insufficiency - drug therapy | Blood Coagulation Disorders - physiopathology | Hypovolemia - etiology | Plasma Substitutes - adverse effects | Shock | Intravenous therapy | Care and treatment | Research | Health aspects | Plasma | Blood
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7. Full Text Moderate plasma dilution using artificial plasma expanders shifts the haemostatic balance to hypercoagulation
by Sinauridze, Elena I and Gorbatenko, Alexander S and Seregina, Elena A and Lipets, Elena N and Ataullakhanov, Fazoil I
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 843 - 12
Artificial plasma expanders (PEs) are widely used in modern transfusion medicine. PEs do not contain components of the coagulation system, so their infusion in... 
THROMBIN GENERATION | IN-VITRO | BLOOD-LOSS | MULTIDISCIPLINARY SCIENCES | DISSEMINATED INTRAVASCULAR COAGULATION | CLOT GROWTH | MASSIVE TRANSFUSION | HEMODILUTION | TRAUMA-INDUCED COAGULOPATHY | PROCOAGULANT ACTIVITY | PLATELET REACTIVITY | Plasma | Thrombin | pH effects | Clotting | Spatial discrimination | Coagulation
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8. Full Text Semisynthetic supra plasma expanders: a new class of therapeutics to improve microcircualtion in sickle cell anaemia
by Meng, Fantao and Kaul, Dhananjaya and Thangaswamy, Sangeetha and Bhutoria, Savita and Gerfen, Gary and Branch, Craig and Intaglietta, Marcos and Acharya, Seetharama A
Artificial Cells, Nanomedicine, and Biotechnology, ISSN 2169-1401, 12/2019, Volume 47, Issue 1, pp. 73 - 82
Compromised microcirculation and endothelial dysfunction are hallmarks of sickle cell disease (SCD). EAF PEG Haemoglobin (Hb) and EAF PEG Albumin (Alb)... 
tempo | plasma expanders | anti vaso-occlusion | EAF PEGylation | sickle cell disease | HEMOGLOBIN | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | VOLUME | EXTREME HEMODILUTION | FLOW | OXYGEN | CARBON-MONOXIDE | TRANSFUSION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ALBUMIN | POLYETHYLENE-GLYCOL | BLOOD
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9. Fluid expanders: Looking afterload(s)
by Guillot, M and Castelain, V
Minerva Anestesiologica, ISSN 0375-9393, 07/2011, Volume 77, Issue 7, pp. 669 - 670
HEMORRHAGIC-SHOCK | ANESTHESIOLOGY | CRITICAL CARE MEDICINE | Heart - drug effects | Male | Animals | Serum Albumin - pharmacology | Plasma Substitutes - pharmacology
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10. Full Text A randomized, single‐blind, increasing dose safety trial of an oxygen‐carrying plasma expander (Hemospan®) administered to orthopaedic surgery patients with spinal anaesthesia
by Olofsson, C and Nygårds, E. B and Ponzer, S and Fagrell, B and Przybelski, R and Keipert, P. E and Winslow, N and Winslow, R. M
Transfusion Medicine, ISSN 0958-7578, 02/2008, Volume 18, Issue 1, pp. 28 - 39
summary The objective of this study was to further explore the safety of Hemospan® (Sangart Inc., San Diego, CA, USA), an oxygen‐carrying plasma expander. The... 
MP4 | blood substitutes | haemoglobin | PEG | haemoglobin‐based oxygen carriers | spinal anaesthesia | oxygen therapeutics | clinical trials | Oxygen therapeutics | Haemoglobin-based oxygen carriers | Blood substitutes | Clinical trials | Haemoglobin | Spinal anaesthesia | HUMAN HEMOGLOBIN | MULTICENTER | DESIGN | SUBSTITUTES | TRANSPORT | haemoglobin-based oxygen carriers | POLYETHYLENE-GLYCOL | HEMATOLOGY | BLOOD | Single-Blind Method | Humans | Middle Aged | Isotonic Solutions - administration & dosage | Contrast Media - pharmacokinetics | Isotonic Solutions - adverse effects | Iohexol - pharmacokinetics | Male | Anesthesia, Spinal | Dose-Response Relationship, Drug | Time Factors | Orthopedic Procedures | Contrast Media - administration & dosage | Plasma Substitutes - administration & dosage | Adult | Female | Iohexol - administration & dosage | Aged | Blood Pressure - drug effects | Isotonic Solutions - pharmacokinetics | Cohort Studies | Plasma Substitutes - adverse effects | Plasma Substitutes - pharmacokinetics | Hospital patients | Surgery
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11. Full Text Improving cardiac function with new-generation plasma volume expanders
by Chatpun, Surapong and Nacharaju, Parimala and Cabrales, Pedro, PhD
American Journal of Emergency Medicine, ISSN 0735-6757, 2013, Volume 31, Issue 1, pp. 54 - 63
Abstract Background Plasma expander (PE) based on polyethylene glycol (PEG) conjugated to albumin has shown positive results maintaining blood volume during... 
Emergency | HEMORRHAGIC-SHOCK | HEMOGLOBIN | PRESSURE | ARM FACILITATED PEGYLATION | EMERGENCY MEDICINE | CONDUCTANCE CATHETER | HUMAN SERUM-ALBUMIN | HEART-FAILURE | LOW-VISCOSITY | PEG-ALBUMIN | EXTREME HEMODILUTION | Cricetinae | Resuscitation - methods | Cardiac Output - drug effects | Ventricular Function, Left - drug effects | Plasma Substitutes - pharmacology | Blood Volume - drug effects | Male | Shock, Hemorrhagic - drug therapy | Hemodilution - methods | Cardiac Catheterization | Animals | Analysis of Variance | Serum Albumin - pharmacology | Mesocricetus | Vascular Resistance - drug effects | Polyethylene Glycols - pharmacology | Albumin | Polyols | Proteins | Heart | Studies | Plasma | Hypotheses | Rodents | Life sciences | Laboratory animals | Catheters | Molecular weight | Veins & arteries | resuscitation from hemorrhagic shock | conductance catheter | hemodilution | cardiac performance
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12. Full Text Clinical relevance of the effects of plasma expanders on coagulation
by Levi, Marcel and Jonge, Evert de
Seminars in thrombosis and hemostasis, ISSN 0094-6176, 2007, Volume 33, Issue 8, pp. 810 - 815
Patients with severe bleeding are often treated with colloids as plasma replacement fluids, including dextrans, gelatin-based solutions, or starches. Many of... 
Plasma expanders | Dextrans | Plasma substitutes | Hemostasis | Coagulation | Starches | Fibrinolysis | Succinylated gelatin | Bleeding | plasma substitutes | bleeding | plasma expanders | BLOOD-COAGULATION | HYDROXYETHYL STARCH | PLATELET-FUNCTION | FACTOR-VIII | CARDIOPULMONARY BYPASS | hemostasis | coagulation | starches | fibrinolysis | CLOT FORMATION | ORTHOPEDIC-SURGERY | CARDIAC-SURGERY | MOLECULAR-WEIGHT HEPARIN | succinylated gelatin | dextrans | PERIPHERAL VASCULAR DISEASE | INTRAVASCULAR VOLUME | HEMATOLOGY | Plasma Substitutes - therapeutic use | Blood Platelets - metabolism | Gelatin - therapeutic use | Humans | Blood Coagulation | Hydroxyethyl Starch Derivatives - therapeutic use | Blood Coagulation Factors - metabolism | Dextrans - therapeutic use
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13. Volume expanders in pediatrics
by Unni, Jeeson C
Indian Journal of Practical Pediatrics, ISSN 0972-9607, 10/2012, Volume 14, Issue 4, pp. 451 - 457
Dextran | Plasma substitutes | Gelatin | Colloids | Volume expanders | Hydroxyethyl starch | Human albumin | Crystalloids
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14. Full Text Carbohydrate plasma expanders for passive tumor targeting: In vitro and in vivo studies
by Hoffmann, Stefan and Caysa, Henrike and Kuntsche, Judith and Kreideweiß, Patrick and Leimert, Anja and Mueller, Thomas and Mäder, Karsten
Carbohydrate Polymers, ISSN 0144-8617, 06/2013, Volume 95, Issue 1, pp. 404 - 413
The objective of this study was to investigate the suitability of carbohydrate plasma volume expanders as a novel polymer platform for tumor targeting. Many... 
Cytokine induction | Hydroxyethyl starch | Tumor accumulation | Multispectral optical imaging | HES | Passive tumor targeting | DRUG | ACTIVATION | POLYMER SCIENCE | CHEMISTRY, ORGANIC | BIODISTRIBUTION | RELEASE | POLYMER THERAPEUTICS | HPMA COPOLYMERS | NANOPARTICLES | PHARMACOKINETICS | ACCUMULATION | CHEMISTRY, APPLIED | HYDROXYETHYL STARCH HES | Leukocytes, Mononuclear - metabolism | Humans | Hydroxyethyl Starch Derivatives - pharmacokinetics | Dextrans - chemistry | Male | Colonic Neoplasms - metabolism | Dextrans - pharmacokinetics | Tissue Distribution | Plasma Substitutes - administration & dosage | Plasma Substitutes - chemistry | Female | Plasma Substitutes - pharmacokinetics | Cell Survival - drug effects | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Hydroxyethyl Starch Derivatives - administration & dosage | Cells, Cultured | Hydroxyethyl Starch Derivatives - chemistry | Hep G2 Cells | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Mice, Nude | Colonic Neoplasms - pathology | Mice | Dextrans - administration & dosage | Dextran | Drugstores | Colon cancer | Tumors
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