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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9613 - 9618
Protection of the endothelium is provided by circulating sphingosine-1-phosphate (S1P), which maintains vascular integrity. We show that HDL-associated S1P is... 
Receptors | Lipoproteins | Lungs | HDL lipoproteins | Lipids | Mice | Cholesterols | Endothelial cells | Endothelium | Crystal structure | Sphingolipids | Endothelial function | Vascular permeability | Atherosclerosis | endothelial function | atherosclerosis | EDG-1 | CELLS | CHOLESTEROL | sphingolipids | MULTIDISCIPLINARY SCIENCES | RECEPTOR | QUANTITATIVE-ANALYSIS | SPHINGOSINE 1-PHOSPHATE | PLASMA | crystal structure | vascular permeability | LIPOPROTEINS | BLOOD | Endothelium, Vascular - cytology | Lysophospholipids - metabolism | Humans | Lipoproteins, HDL - metabolism | Crystallography, X-Ray | Apolipoproteins M | Endocytosis | Apolipoproteins - genetics | Lipocalins - genetics | HEK293 Cells | Lipoproteins, HDL - chemistry | Sphingosine - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptors, Lysosphingolipid - metabolism | Lipocalins - metabolism | Protein Structure, Tertiary | Endothelial Cells - metabolism | Lysophospholipids - chemistry | Apolipoproteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Models, Molecular | Mice, Transgenic | Blotting, Western | Mice, Knockout | Sphingosine - analogs & derivatives | Animals | Endothelium, Vascular - metabolism | Protein Binding | Apolipoproteins - chemistry | Protein Conformation | Enzyme Activation | Lipocalins - chemistry | Sphingosine - chemistry | Mitogen-Activated Protein Kinases - metabolism | Tissue | Apolipoproteins | Rodents | Cell adhesion & migration | Index Medicus | Biological Sciences | Medicinal Chemistry | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | permeability | Medicinska och farmaceutiska grundvetenskaper | vascular | Läkemedelskemi
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2007, Volume 27, Issue 8, pp. 1843 - 1849
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2014, Volume 124, Issue 6, pp. 2750 - 2761
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 10/2006, Volume 103, Issue 44, pp. 16394 - 16399
Mast cells play a pivotal role in inflammatory and immediate-type allergic reactions by secreting a variety of potent inflammatory mediators, including... 
multidrug resistance | FC-EPSILON-RI | sphingolipids | sphingosine kinase | MULTIDISCIPLINARY SCIENCES | KINASE | allergic responses | RECEPTOR | PLASMA-MEMBRANE | SPHINGOSINE 1-PHOSPHATE | P-GLYCOPROTEIN | secretion | EFFLUX PUMP | GROWTH-FACTOR | MULTIDRUG-RESISTANCE PROTEIN-1 | DEPENDENT ACTIVATION
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2017, Volume 7, Issue 1, pp. 14983 - 10
Sphingosine-1-phosphate (S1P) is a bioactive lipid implicated in e.g. angiogenesis, lymphocyte trafficking, and endothelial barrier function. Erythrocytes are... 
HDL | OVEREXPRESSION | PLASMA-LEVELS | MULTIDISCIPLINARY SCIENCES | RECEPTOR | FUNCTIONAL-CHARACTERIZATION | MOLECULAR-CLONING | MICE | HIGH-DENSITY-LIPOPROTEIN | SPHINGOSINE 1-PHOSPHATE | BLOOD | Angiogenesis | Erythrocytes | Albumin | Apolipoproteins | Lipoproteins (high density) | Adenosine triphosphatase | Endothelial cells | Sphingosine 1-phosphate | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7560, pp. 342 - 346
Lipid mediators influence immunity in myriad ways. For example, circulating sphingosine-1-phosphate (S1P) is a key regulator of lymphocyte egress(1,2).... 
SPHINGOSINE 1-PHOSPHATE RECEPTOR | PROGENITOR | S1P | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | APOLIPOPROTEIN-M | CHOLESTEROL EFFLUX | LYMPHOCYTE EGRESS | EXPRESSION | SERUM-LIPID PROFILES | BLOOD | Fingolimod Hydrochloride - pharmacology | Inflammation - pathology | Lysophospholipids - metabolism | Lymphopoiesis | Central Nervous System - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Lipoproteins, HDL - metabolism | Central Nervous System - pathology | Encephalomyelitis, Autoimmune, Experimental - immunology | Male | Central Nervous System - immunology | Apolipoproteins - deficiency | Apolipoproteins M | Inflammation - metabolism | Lysophospholipids - agonists | Lymphocytes - immunology | Apolipoproteins - genetics | Sphingosine - agonists | Female | Sphingosine - metabolism | Encephalomyelitis, Autoimmune, Experimental - genetics | Receptors, Lysosphingolipid - metabolism | Lymphocytes - metabolism | Cell Proliferation - genetics | Encephalomyelitis, Autoimmune, Experimental - pathology | Signal Transduction | Lymphoid Progenitor Cells - metabolism | Apolipoproteins - metabolism | Mice, Inbred C57BL | Hematopoietic Stem Cells - metabolism | Inflammation - immunology | Lymphocytes - cytology | Lymphoid Progenitor Cells - cytology | Lysophospholipids - blood | Blood-Brain Barrier - pathology | Lysophospholipids - genetics | Sphingosine - analogs & derivatives | Animals | Hematopoietic Stem Cells - cytology | Protein Binding | Sphingosine - blood | Sphingosine - genetics | Mice | Cell Movement | Spleen | Plasma | Lymphatic system | Lymphocytes | Bone marrow | Homeostasis | Physiology | Index Medicus
Journal Article
Science, ISSN 0036-8075, 4/2007, Volume 316, Issue 5822, pp. 295 - 298
Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 3, pp. e91346 - e91346
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, pp. e38941 - e38941
Sphingosine-1-phosphate (S1P), a sphingolipid metabolite that is produced inside the cells, regulates a variety of physiological and pathological responses via... 
IMMUNOMODULATOR FTY720 | ERYTHROCYTES | METABOLISM | PLATELETS | MAST-CELLS | BIOLOGY | RECEPTOR | RELEASE | LYMPHOCYTE EGRESS | SPHINGOSINE 1-PHOSPHATE | BLOOD | Lymphocytes - metabolism | Gene Targeting | Lysophospholipids - metabolism | Endothelial Cells - metabolism | Humans | Mice, Inbred C57BL | Male | Lysophospholipids - blood | Anion Transport Proteins - metabolism | Mice, Knockout | Sphingosine - analogs & derivatives | Animals | Blood Platelets - metabolism | Anion Transport Proteins - deficiency | Erythrocytes - metabolism | Sphingosine - blood | Female | Transcription, Genetic | Mice | Sphingosine - metabolism | Thymus Gland - metabolism | Anion Transport Proteins - genetics | Phosphates | Sphingosine | Physiological aspects | Lipids | Cellular signal transduction | B cells | Endothelium | Motility | Leukocyte migration | Erythrocytes | Biology | Egress | Kinases | Phosphatase | Thymus | Sphingosine 1-phosphate | Blood plasma | Proteins | Genotype & phenotype | Signal transduction | Receptors | Biomedical materials | Red blood cells | Lymphocytes | Rodents | Biocompatibility | Physiology | Chemical synthesis | Pharmaceutical sciences | Concentration gradient | Quantitative analysis | Antigens | Phosphate transporter | Zebrafish | Pharmacology | Mammals | Exports | Endothelial cells | Signaling | Lymphopenia | Osteoclasts | Transduction | Platelets | Transporter | Cell migration | Cancer | Index Medicus
Journal Article