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Xenobiotica, ISSN 0049-8254, 05/2019, Volume 49, Issue 5, pp. 584 - 590
The pharmacokinetics of TAK-272 (SCO-272), an orally active renin inhibitor, was investigated in rats with subcutaneously injected turpentine oil, which was an... 
TAK-272 | plasma protein binding | Pharmacokinetics | acid glycoprotein
Journal Article
Fish and Shellfish Immunology, ISSN 1050-4648, 11/2019, Volume 94, pp. 66 - 71
Astakine 1 is a small cytokine-like peptide which is directly involved in hematopoiesis in crustaceans. Astakines are present in many different invertebrate... 
Plasma protein | Pacifastacus leniusculus | Hematopoiesis | Cytokine | Index Medicus
Journal Article
04/2007
The effect of an aqueous extract prepared from the leaves of Viscum album (Mistletoe) on plasma cholesterol and albumin levels in male Wistar rats was studied.... 
extract | safe | Lipid profile | mistletoe | plasma protein
Web Resource
07/2009
The degree of binding of a drug to plasma proteins has a marked effect on its distribution, elimination, and pharmacological effect since only the unbound... 
Bovine serum albumin | Arsenic | Plasma protein-binding | Drug interactions | Atenolol
Web Resource
Circulation Journal, ISSN 1346-9843, 2019
Background: Recent studies have suggested that pregnancy-associated plasma protein-A (PAPP-A) is involved in the pathogenesis of atherosclerosis. This study... 
Atherosclerosis | Pregnancy-associated plasma protein-A | Reverse cholesterol transport | Inflammation
Journal Article
Food Chemistry, ISSN 0308-8146, 2010, Volume 118, Issue 2, pp. 403 - 410
Antioxidant activity and functional properties of porcine blood plasma protein hydrolysates (PPH) prepared with Alcalase at 6.2%, 12.7% and 17.6% of degree of... 
Functional properties | Porcine plasma protein hydrolysate | Purification | Antioxidant peptide | OXIDATION | NUTRITION & DIETETICS | PEPTIDES | AMINO-ACIDS | FOOD SCIENCE & TECHNOLOGY | MUSCLE | CHEMISTRY, APPLIED | WHEAT
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 02/2019, Volume 104, Issue 2, pp. 349 - 358
Context: Breast cancer is the most common malignancy in women. Noninvasive biomarkers are needed for its early diagnosis and/or prognosis. Objective: The aim... 
MAMMOGRAPHY | WOMEN | CANCER RISK | METAANALYSIS | ENDOCRINOLOGY & METABOLISM | RECURRENCE | FACTOR-I | DIFFERENTIATION | EXPRESSION | CARCINOMA | PLASMA PROTEIN-A
Journal Article
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, ISSN 0021-972X, 07/2003, Volume 88, Issue 7, pp. 3236 - 3240
Vascular endothelial dysfunction has been demonstrated in overweight or obese patients, but the molecular basis for this link has not been clarified. We asked... 
OBESITY | ADIPONECTIN | INSULIN-RESISTANCE | GLUCOSE | ENDOCRINOLOGY & METABOLISM | NITRIC-OXIDE | SENSITIVITY | PLASMA-PROTEIN | REACTIVE HYPEREMIA | ASSOCIATION
Journal Article
Journal of Obstetrics and Gynaecology Canada, ISSN 1701-2163, 06/2018, Volume 40, Issue 6, pp. 663 - 668
First-trimester low concentration of pregnancy-associated plasma protein A (PAPP-A) has been associated with adverse perinatal outcomes in high-risk... 
Pregnancy | preeclampsia | pregnancy-associated plasma protein-A | fetus
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 12/2015, Volume 1423, pp. 63 - 70
The surging demand for plasma proteins, mainly driven by the growing market and the development of new therapeutic indications, is promoting manufacturers to... 
Hydrophobic interaction | Ion-exchange | Membrane chromatography | Plasma protein | Membrane adsorber | α1-Antitrypsin | Antitrypsin
Journal Article
by Yi, Q and Han, XH and Fan, ZH and Ma, YH and Zhu, GZ and Qiang, W and Wang, L and Cheng, ZN
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, ISSN 0731-7085, 01/2019, Volume 163, pp. 17 - 23
As a PAC-1 derivative, SM-1 exhibts a promising antitumour property. To better understand the relationship between the drug concentrations and pharmacological... 
CHEMISTRY, ANALYTICAL | Plasma protein binding | SM-1 | PHARMACOLOGY & PHARMACY | Tissue distribution | Anti-tumour drugs | Pharmacokinetics
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2019, Volume 62, Issue 5, pp. 2245 - 2255
Due to its implications for both dose level and frequency, clearance rate is one of the most important pharmacokinetic parameters to consider in the design of... 
HALF-LIFE | HEPATOCYTES | CHEMISTRY, MEDICINAL | METABOLISM | IN-VIVO | HUMANS | LIVER-MICROSOMES | INTRINSIC CLEARANCE | PLASMA-PROTEIN BINDING | DISPOSITION | PREDICTION
Journal Article
Integrative Biology (United Kingdom), ISSN 1757-9694, 12/2012, Volume 5, Issue 1, pp. 66 - 73
The Nanotechnology Characterization Laboratory's (NCL) unique set-up has allowed our lab to handle and test a variety of nanoparticle platforms intended for... 
IN-VITRO | NICKEL | NANOPARTICLE FORMULATIONS | PARTICLE-SIZE | TOXICITY | ENDOTOXIN REMOVAL | C-60 | PLASMA-PROTEIN BINDING | RADIATION | SURFACES | CELL BIOLOGY | Index Medicus
Journal Article
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, ISSN 0305-7453, 07/2019, Volume 74, Issue 7, pp. 1975 - 1983
Objectives Cefoxitin is frequently used for surgical antibiotic prophylaxis (SAP). Using microdialysis, we evaluated whether the currently recommended dosing... 
INFECTIOUS DISEASES | SURGICAL SITE INFECTION | MORBIDLY OBESE | RISK | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | PLASMA-PROTEIN BINDING | ANTIBIOTIC-PROPHYLAXIS | CEFAZOLIN
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 03/2008, Volume 8, Issue 4, pp. 270 - 280
Implantable medical devices are increasingly important in the practice of modern medicine. Unfortunately, almost all medical devices suffer to a different... 
Proteins | Biocompatibility | Cells | Functional groups | Biomaterials | CHEMISTRY, MEDICINAL | SELF-ASSEMBLED MONOLAYERS | biocompatibility | INFLAMMATORY RESPONSES | ADSORBED FIBRINOGEN | CELL-ADHESION | PLATELET-ADHESION | PLASMA-PROTEIN ADSORPTION | IN-VITRO | cells | CONFORMATIONAL-CHANGES | proteins | FIBRINOGEN ADSORPTION | functional groups | FUNCTIONAL-GROUPS | biomaterials
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2018, Volume 61, Issue 24, pp. 11349 - 11371
Tuberculosis and parasitic diseases, such as giardiasis, amebiasis, leishmaniasis, and trypanosomiasis, all urgently require improved treatment options.... 
MYCOBACTERIUM-TUBERCULOSIS | DRUG | VITRO | CHEMISTRY, MEDICINAL | PLASMA-PROTEIN | ENTAMOEBA-HISTOLYTICA | IN-VIVO ACTIVITIES | METRONIDAZOLE | BINDING DATA | AGONISTS | LEAD
Journal Article
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