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The Journal of Cell Biology, ISSN 0021-9525, 12/1995, Volume 131, Issue 6, pp. 1609 - 1622
The GPI-anchored urokinase plasminogen activator receptor (uPAR) does not internalize free urokinase (uPA). On the contrary, uPAR-bound complexes of uPA with... 
Receptors | Plasminogen activators | Lipoproteins | Internalization | Cell lines | Antibodies | Ligands | Cell membranes | Cellular immunity | Cells | Physiological aspects | Urokinase | Cell receptors | Proteins | Cellular biology | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2007, Volume 282, Issue 18, pp. 13561 - 13572
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0168418 - e0168418
In high grade glioma (HGG), extensive tumor cell infiltration of normal brain typically precludes identifying effective margins for surgical resection or... 
GROWTH-FACTOR RECEPTOR | PROTEIN | MULTIDISCIPLINARY SCIENCES | UROKINASE RECEPTOR | EXTRACELLULAR-MATRIX | UPAR | PLASMINOGEN-ACTIVATOR RECEPTOR | GLIOBLASTOMA CELLS | EGF RECEPTOR | MUTANT EGFR | CANCER STEM-CELLS | Cell Survival - drug effects | Receptor, Epidermal Growth Factor - genetics | Cell Proliferation - genetics | Receptors, G-Protein-Coupled - metabolism | Humans | Cell Survival - genetics | Cell Movement - genetics | Glioma - metabolism | Glioma - genetics | Cell Movement - drug effects | Receptor, Epidermal Growth Factor - metabolism | Receptors, Formyl Peptide - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Receptors, G-Protein-Coupled - genetics | Receptors, Lipoxin - genetics | Receptors, Lipoxin - metabolism | Microscopy, Fluorescence | Receptors, Formyl Peptide - genetics | Pertussis Toxin - pharmacology | Care and treatment | Gliomas | Physiological aspects | Development and progression | Genetic aspects | Research | Metastasis | Pertussis toxin | Vimentin | Cell proliferation | Brain | Membranes | G protein-coupled receptors | Mesenchyme | Radiation | Metastases | Cell adhesion & migration | Proteins | Pertussis | Urokinase | Receptors | Epidermal growth factor | Glioma cells | Surgery | Neurospheres | Inhibition | Cell survival | Epidermal growth factor receptors | Gene expression | Whooping cough | U-Plasminogen activator | Pathology | Signaling | Gene amplification | Inhibitors | Cell lines | Stem cells | Irradiation | Infiltration | Cell migration | Cancer | Neutralization | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/2008, Volume 107, Issue 4, pp. 1091 - 1101
Glutamate is the main excitatory neurotransmitter of the CNS. Tissue‐type plasminogen activator (tPA) is recognized as a modulator of glutamatergic... 
serine protease inhibitor | NMDA receptor | low‐density lipoprotein receptor family | tissue‐type plasminogen activator | plasmin | Low-density lipoprotein receptor family | Serine protease inhibitor | Tissue-type plasminogen activator | Plasmin | low-density lipoprotein receptor family | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXCITOTOXIC INJURY | BLOOD-BRAIN-BARRIER | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | SUBSTRATE-SPECIFICITY | PROTEOLYTIC ACTIVITY | IN-VIVO | INHIBITOR COMPLEXES | LONG-TERM POTENTIATION | tissue-type plasminogen activator | METHYL-D-ASPARTATE | CALCIUM RESPONSES | Age Factors | Calcium - metabolism | Membrane Potentials - radiation effects | Cerebral Cortex - cytology | Oocytes | N-Methylaspartate - pharmacology | Drug Interactions | Thrombin - pharmacology | Amyloid beta-Protein Precursor - metabolism | Neurons - drug effects | Animals, Newborn | Membrane Potentials - drug effects | Receptors, N-Methyl-D-Aspartate - drug effects | Glutamic Acid - pharmacology | Mice, Inbred C57BL | Xenopus laevis | Cells, Cultured | Rats | Receptors, Cell Surface - metabolism | Membrane Potentials - physiology | Receptors, N-Methyl-D-Aspartate - physiology | rap GTP-Binding Proteins - pharmacology | Patch-Clamp Techniques | Animals | Tissue Plasminogen Activator - pharmacology | Glycine - pharmacology | Protease Nexins | Mice | Fibrinolysin - pharmacology | Methyl aspartate | Thrombin | Protease inhibitors | Tissue plasminogen activator | Low density lipoproteins | Domestic relations | Neurology | Signal transduction | Neurotransmitters | Biochemistry | Substrates | Index Medicus
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2011, Volume 17, Issue 8, pp. 952 - 960
Journal Article
Stroke, ISSN 0039-2499, 01/2014, Volume 45, Issue 1, pp. 18 - 23
Journal Article
ONCOGENE, ISSN 0950-9232, 09/2012, Volume 31, Issue 37, pp. 4150 - 4163
MicroRNAs (miRNAs) as modulators of gene expression have been described to display both tumor-promoting and tumor-suppressive functions. Although their role... 
ACTIVATION | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | miR-520c | breast cancer | NF-kappaB | PROLIFERATION | MICRORNAS | ER-negative | CELL BIOLOGY | TGF-beta | INVASION | miR-373 | ONCOLOGY | EMBRYONIC STEM-CELLS | GENETICS & HEREDITY | BONE METASTASIS | GROWTH-FACTOR | UP-REGULATION | EXPRESSION | Receptors, Estrogen - metabolism | Receptors, Transforming Growth Factor beta - genetics | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | NF-kappa B - metabolism | Gene Expression Profiling | Receptors, Estrogen - deficiency | Transcription Factor RelA - genetics | Breast Neoplasms - metabolism | Parathyroid Hormone-Related Protein - biosynthesis | Angiopoietin-like 4 Protein | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Protein-Serine-Threonine Kinases - metabolism | Angiopoietins - biosynthesis | Signal Transduction | Interleukin-8 - biosynthesis | Protein-Serine-Threonine Kinases - genetics | Parathyroid Hormone-Related Protein - metabolism | Neoplasm Metastasis - genetics | Plasminogen Activator Inhibitor 1 - biosynthesis | Breast Neoplasms - genetics | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Transcription Factor RelA - metabolism | Cell Line, Tumor | Interleukin-6 - biosynthesis | Transforming Growth Factor beta - metabolism | Index Medicus | Tumor cells | Estrogen receptors | Breast cancer | Genomes | Inflammation | Transforming growth factor- beta | Gene expression | Lymph nodes | Metastases | Parathyroid hormone-related protein | plasminogen | Signal transduction | NF- Kappa B protein | Tumor suppressor genes | miRNA | RelA protein | Interleukin 8 | Tumors
Journal Article