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plcβ (26) 26
animals (16) 16
index medicus (13) 13
cell biology (12) 12
humans (11) 11
plc beta (11) 11
signal transduction (10) 10
biochemistry & molecular biology (9) 9
mice (7) 7
plc-β (7) 7
phospholipase c beta - metabolism (6) 6
phosphorylation (6) 6
activation (5) 5
calcium - metabolism (5) 5
cell line (5) 5
g protein (5) 5
phospholipase c beta (5) 5
pi turnover (5) 5
signal transduction - drug effects (5) 5
expression (4) 4
gpcr (4) 4
gαq (4) 4
oxidative stress (4) 4
ras (4) 4
rats (4) 4
amino acid sequence (3) 3
article (3) 3
biophysics (3) 3
cells (3) 3
erk (3) 3
g-alpha (3) 3
gene-expression (3) 3
gqα (3) 3
gqα protein (3) 3
gtp-binding protein alpha subunits, gq-g11 - metabolism (3) 3
high glucose (3) 3
histamine (3) 3
isoenzymes - metabolism (3) 3
kinase-c (3) 3
male (3) 3
models, biological (3) 3
neurosciences (3) 3
phospholipase c beta - genetics (3) 3
phospholipase c-β (3) 3
phospholipase-c (3) 3
phospholipases (3) 3
pkc (3) 3
plc β (3) 3
plc-beta (3) 3
protein-kinase-c (3) 3
receptor (3) 3
smooth-muscle (3) 3
type c phospholipases - metabolism (3) 3
vsmc (3) 3
2-apb, 2-aminoethoxyphenylborane (2) 2
[ca2+]i, intracellular free ca2+ concentration (2) 2
ac, adenylyl cyclase (2) 2
adult (2) 2
airway smooth muscle (2) 2
akt (2) 2
angiotensin-ii (2) 2
asm, airway smooth muscle (2) 2
ca2+ signaling (2) 2
calcium (2) 2
calcium signaling (2) 2
camk ii (2) 2
camp (2) 2
camp, 3',5'-cyclic amp (2) 2
cardiovascular system (2) 2
carrier proteins - metabolism (2) 2
cell membrane - metabolism (2) 2
cells, cultured (2) 2
chondrocytes (2) 2
copd, chronic obstructive pulmonary disease (2) 2
csrc (2) 2
cyclic amp (2) 2
desensitization (2) 2
diacylglycerol (2) 2
dmso, dimethyl sulfoxide (2) 2
ec50, half-maximally effective (2) 2
endocrinology & metabolism (2) 2
epac, exchange protein activated by camp (2) 2
female (2) 2
g-protein (2) 2
gpcr, g protein-coupled receptor (2) 2
gq alpha (2) 2
gq alpha protein (2) 2
growth factor receptor (2) 2
gtpase-activating protein (2) 2
ha, haemagglutinin (2) 2
hbasmc, human bronchial airway smooth muscle cell (2) 2
hbs, hepes-buffered saline (2) 2
hbss, hank’s balanced salt solution (2) 2
hela cells (2) 2
heterotrimeric g proteins (2) 2
heterotrimeric g-proteins (2) 2
heterotrimeric gtp-binding proteins - metabolism (2) 2
ibmx, 3-isobutyl-1-methylxanthine (2) 2
identification (2) 2
in-vitro (2) 2
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1. Full Text Phospholipase C-β in immune cells
by Kawakami, Toshiaki and Xiao, Wenbin
Advances in Biological Regulation, ISSN 2212-4926, 09/2013, Volume 53, Issue 3, pp. 249 - 257
Great progress has recently been made in structural and functional research of phospholipase C (PLC)-β. We now understand how PLC-β isoforms (β1-β4) are... 
Myeloid Cells - enzymology | Immune System - enzymology | Isoenzymes - genetics | Humans | Immune System - cytology | Isoenzymes - immunology | Phospholipase C beta - genetics | Animals | Lymphocytes - immunology | Myeloid Cells - immunology | Phospholipase C beta - immunology | Immune System - immunology | Lymphocytes - enzymology | mast cell | macrophage | neutrophil | PLC-β | G protein | lymphocyte
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2. Full Text Calcium and phospholipase Cβ signaling through dopamine receptors
by Chun, Lani S and Benjamin Free, R and Sibley, David R
Neuromethods, ISSN 0893-2336, 2015, Volume 96, pp. 251 - 263
Fluo-8 | 5-triphosphate | Calcium | heteromer | Dopamine receptor | protein | Inositol 1 | IP3 | PLCβ | Inositol 1,4,5-triphosphate
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3. Full Text Gβγ-mediated activation of protein kinase D exhibits subunit specificity and requires Gβγ-responsive phospholipase Cβ isoforms
by Lau, Winnie W.I and Chan, Anthony S.L and Poon, Lydia S.W and Zhu, Jing and Wong, Yung H
Cell Communication and Signaling, ISSN 1478-811X, 2013, Volume 11, Issue 1, pp. 22 - 22
Protein kinase D (PKD) constitutes a novel family of serine/threonine protein kinases implicated in fundamental biological activities including cell... 
Gα subunits | PKD | G proteins | Gβγ dimers | PLCβ
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4. Full Text G-protein-activated phospholipase C-β, new partners for cell polarity proteins Par3 and Par6
by Cai, Yi and Stafford, Lewis J and Bryan, Brad A and Mitchell, Dianne and Liu, Mingyao
Oncogene, ISSN 0950-9232, 06/2005, Volume 24, Issue 26, pp. 4293 - 4300
Cell polarity and asymmetric cell division are fundamental traits of all living cells and play an essential role in embryonic development, neuronal cell... 
G-protein | Cell polarity | Cell asymmetric division | PDZ domain | PLC-β | LOCALIZATION | PLC-beta | G-ALPHA | cell asymmetric division | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE-C | CAENORHABDITIS-ELEGANS EMBRYOS | DIVISION | CELL BIOLOGY | CDC42 | DIRECT BINDING | ONCOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | cell polarity | DROSOPHILA NEUROBLASTS | PLANAR POLARITY | GTP-Binding Proteins - pharmacology | Receptors, Thrombin - biosynthesis | Signal Transduction | Carrier Proteins - biosynthesis | Humans | Kidney - cytology | Type C Phospholipases - biosynthesis | Type C Phospholipases - pharmacology | Cell Division - physiology | Hydrolysis | Cell Polarity - genetics | Adaptor Proteins, Signal Transducing | Phospholipase C beta | Carrier Proteins - metabolism | Transfection | Isoenzymes - pharmacology | Receptors, Thrombin - metabolism | Cell Polarity - physiology | Transcription, Genetic | Cell Culture Techniques | Isoenzymes - biosynthesis
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5. Full Text Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase Cβ in mouse brain
by Watanabe, Masahiko and Nakamura, Michiko and Sato, Kazunori and Kano, Masanobu and Simon, Melvin I and Inoue, Yoshiro
European Journal of Neuroscience, ISSN 0953-816X, 06/1998, Volume 10, Issue 6, pp. 2016 - 2025
Ligand binding to neurotransmitter and hormone receptors which couple to the Gq subclass of GTP‐binding protein leads to the activation of phospholipase Cβ... 
development | GTP‐binding protein | PLCβ | in situ hybridization | Development | GTP-binding protein | In situ hybridization | ALPHA-SUBUNITS | METABOTROPIC GLUTAMATE RECEPTOR | NEUROSCIENCES | PROTEIN KINASE-C | MESSENGER-RNAS | PLC beta | GENE | SEQUENCE | MOLECULAR-CLONING | RAT-BRAIN | INSITU HYBRIDIZATION | SIGNAL TRANSDUCTION
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6. Full Text Crystal structure of phospholipase PA2-Vb, a protease-activated receptor agonist from the Trimeresurus stejnegeri snake venom
by Zeng, Fuxing and Zhang, Wenjuan and Xue, Nairui and Teng, Maikun and Li, Xu and Shen, Bing
FEBS Letters, ISSN 0014-5793, 12/2014, Volume 588, Issue 24, pp. 4604 - 4612
Phospholipase A (PLA ) is an important component in snake venoms. Here, an acidic PLA , designated PA2-Vb was isolated from the snake venom. PA2-Vb acts on a... 
Vasoconstrictor activity | Acidic phospholipase A2 | Ca2+ release | IP3 receptor | Crystal structure | IP3R | phospholipase Cβ | RyR | sarcoplasmic reticulum | 2-APB | svPLA2 | reversible permeabilization | GPCRs | ryanodine receptor | vascular smooth muscle cells | VSMCs | PAR-1 | protease-activated receptor 1 | 2-aminoethoxy diphenyl borate | G-protein coupled receptors | PLA2 | p-bromofenacil bromide | PLCβ | snake venom PLA2 | phospholipases A2 | pBPB | inositol 1,4,5-trisphosphate receptor | Acidic phospholipase A | receptor | release | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-RAY-DIFFRACTION | SARCOPLASMIC-RETICULUM | RELEASE | CELL BIOLOGY | NAJA-NAJA | SMOOTH-MUSCLE | INOSITOL 1,4,5-TRISPHOSPHATE | BIOPHYSICS | CHANNELS | VASOCONSTRICTION | Amino Acid Sequence | Calcium - metabolism | Protein Multimerization | Models, Molecular | Molecular Sequence Data | Phospholipases A2 - pharmacology | Crystallography, X-Ray | Crotalid Venoms - enzymology | Muscle, Smooth, Vascular - cytology | Vasoconstriction - drug effects | Animals | Receptors, Proteinase-Activated - agonists | Protein Structure, Quaternary | Phospholipases A2 - isolation & purification | Muscle, Smooth, Vascular - physiology | Trimeresurus | Hydrogen-Ion Concentration | Muscle, Smooth, Vascular - drug effects | Phospholipases A2 - chemistry | Inositol | Phospholipases | Structure | Proteases | Venom | Crystals | Snakes | Borates
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7. Full Text Selective inhibition of histamine-evoked Ca2+ signals by compartmentalized cAMP in human bronchial airway smooth muscle cells
by Dale, Philippa and Head, Victoria and Dowling, Mark R and Taylor, Colin W
Cell Calcium, ISSN 0143-4160, 05/2018, Volume 71, pp. 53 - 64
Intracellular Ca and cAMP typically cause opposing effects on airway smooth muscle contraction. Receptors that stimulate these pathways are therapeutic targets... 
Protein kinase A | Cyclic AMP | Histamine | Ca2+ signaling | Airway smooth muscle | Spatial organization | signaling | PROTEIN-KINASE-A | PHOSPHOINOSITIDE METABOLISM | EP4 RECEPTORS | Histamine Protein kinase A | MUSCARINIC RECEPTORS | IP3 RECEPTORS | FUNCTIONAL ANTAGONISM | CELL BIOLOGY | BETA-ADRENOCEPTOR AGONISTS | PROSTANOID RECEPTORS | CYCLIC-AMP | INOSITOL 1,4,5-TRISPHOSPHATE | PLCβ, phospholipase C β | COPD, chronic obstructive pulmonary disease | hBASMC, human bronchial airway smooth muscle cell | PGE2, prostaglandin E2 | AC, adenylyl cyclase | HBSS, Hank’s balanced salt solution | LPA, 18:1 lysophosphatidic acid | HBS, Hepes-buffered saline | Epac, exchange protein activated by cAMP | GPCR, G protein-coupled receptor | IP3, inositol 1,4,5-trisphosphate | PKI-myr, myristoylated PKA inhibitor | 2-APB, 2-aminoethoxyphenylborane | pEC50, -logEC50 | PTX, pertussis toxin | PKA, cyclic AMP-dependent protein kinase | [Ca2+]i, intracellular free Ca2+ concentration | IP3R, IP3 receptor | IBMX, 3-isobutyl-1-methylxanthine | DMSO, dimethyl sulfoxide | EC50 (IC50), half-maximally effective (inhibitory) concentration | ASM, airway smooth muscle | cAMP, 3',5'-cyclic AMP
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8. Full Text Selective inhibition of histamine-evoked Ca2+ signals by compartmentalized cAMP in human bronchial airway smooth muscle cells
by Dale, Philippa and Head, Victoria and Dowling, Mark R and Taylor, Colin William
ISSN 0143-4160, 2018
Intracellular Ca2+ and cAMP typically cause opposing effects on airway smooth muscle contraction. Receptors that stimulate these pathways are therapeutic... 
Bronchi | Humans | Pertussis Toxin | Dinoprostone | Cyclic AMP | Child, Preschool | Isoproterenol | Cell Compartmentation | Receptors, Prostaglandin E, EP4 Subtype | Histamine | Myocytes, Smooth Muscle | Receptors, Prostaglandin E, EP2 Subtype | Inositol 1,4,5-Trisphosphate Receptors | Adult | Type C Phospholipases | Child | Cyclic AMP-Dependent Protein Kinases | Calcium Signaling
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9. Full Text Fibroblast growth factor-2 stimulates phospholipase C β in adult cardiomyocytes
by Tappia, Paramjit S and Panagia, Vincenzo and Padua, Raymond R and Kardami, Elissavet
Biochemistry and Cell Biology, ISSN 0829-8211, 12/1999, Volume 77, Issue 6, pp. 569 - 575
Although fibroblast growth factor-2 (FGF-2) plays an important role in cardioprotection and growth, little is known about the signals triggered by it in the... 
PLC γ | FGF-2 | Signal transduction | Cardiomyocytes | PLC β
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10. Full Text The role of CNP-mediated PKG/PKA-PLCβ pathway in diabetes-induced gastric motility disorder
by Guo, Jun-Yu and Zhang, Mo-Han and Jiang, Jing-Zhi and Piao, Li-Hua and Fang, Xue-Sen and Jin, Zheng and Cai, Ying-Lan
Peptides, ISSN 0196-9781, 12/2018, Volume 110, pp. 47 - 55
Our previous work demonstrated that the C-type natriuretic peptide (CNP)/cyclic guanosine monophosphate (cGMP)/cyclic adenosine monophosphate (cAMP) pathway in... 
PKG /PKA -PLCβ | Trisphosphate inositol | C-type natriuretic peptide | β-type phospholipase C | Diabetic gastric dysmotility | NATRIURETIC-PEPTIDE | SMOOTH-MUSCLE | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | beta-type phospholipase C | PKG /PKA -PLC beta | PKA | ENDOCRINOLOGY & METABOLISM | PHARMACOLOGY & PHARMACY
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11. Full Text The Roles of PDZ-Containing Proteins in PLC-β-Mediated Signaling
by Suh, Pann-Ghill and Hwang, Jong-Ik and Ho Ryu, Sung and Donowitz, Mark and Ho Kim, Jae
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2001, Volume 288, Issue 1, pp. 1 - 7
Mammalian phospholipase C- isozymes are activated by a heterotrimeric GTP-binding protein linked to various cell surface receptors. Recent reports suggest that... 
E3KARP | NHERF | Trp | phospholipase C-β (PLC-β) | G-protein-coupled receptor | INAD | PDZ domain | phospholipase C- (PLC- ) | Phospholipase C-β(PLC-β) | Protein Structure, Tertiary | Drosophila Proteins | Calcium Channels - metabolism | Signal Transduction | TRPC Cation Channels | Sodium-Hydrogen Exchangers | Isoenzymes - chemistry | Type C Phospholipases - chemistry | Drosophila - physiology | Phospholipase C beta | Animals | Eye Proteins - metabolism | Models, Biological | Vision, Ocular | Phosphoproteins - physiology | Cytoskeletal Proteins - physiology | Type C Phospholipases - physiology | Isoenzymes - physiology
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12. Full Text KN-93 inhibition of G protein signaling is independent of the ability of Ca 2+/calmodulin-dependent protein kinase II to phosphorylate phospholipase Cβ 3 on 537-Ser
by Yue, Caiping and Sanborn, Barbara M
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2001, Volume 175, Issue 1, pp. 149 - 156
Phosphorylation | CaMK II | PI turnover | PLCβ | G protein
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13. Full Text Gαq binds to p110α/p85α phosphoinositide 3-kinase and displaces Ras
by Ballou, Lisa M and Chattopadhyay, Mohar and Li, Yan and Scarlata, Suzanne and Lin, Richard Z
Biochemical Journal, ISSN 0264-6021, 03/2006, Volume 394, Issue 3, pp. 557 - 562
Several studies have reported that activation of Gq-coupled receptors inhibits PI3K (phosphoinositide 3-kinase) signalling. In the present study, we used... 
Fluorescence spectroscopy | Phosphoinositide 3-kinase | Akt | p85 | Ras | IRS-1, insulin receptor substrate-1 | GST, glutathione S-transferase | HEK-293 cells, human embryonic kidney 293 cells | PI3K, phosphoinositide 3-kinase | Gαq | RBD, Ras-binding domain | fluorescence spectroscopy | coumarin, 7-(dimethylamino)coumarin-4-acetic acid succinimidyl ester | MEK, mitogen-activated protein kinase | PS, 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine | HA, haemagglutinin | extracellular-signal-regulated kinase kinase | iSH2, inter-SH2 | LUV, large unilamellar vesicle | POPC, 1-palmitoyl-2-oleoyl phosphatidylcholine | SH2, Src homology 2 | PLCβ, phospholipase Cβ | GTP[S], guanosine 5′-[γ-thio]triphosphate | PDGF, platelet-derived growth factor | phosphoinositide 3-kinase
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14. Full Text Regulation of hematopoietic‐specific G‐protein Gα15 and Gα16 by protein kinase C
by Gu, Jennifer L and Lu, Wei and Xia, Chunzhi and Wu, Xiushan and Liu, Mingyao
Journal of Cellular Biochemistry, ISSN 0730-2312, 04/2003, Volume 88, Issue 6, pp. 1101 - 1111
Heterotrimeric G proteins mediate cell growth and differentiation by coupling cell surface receptors to intracellular effector enzymes. The G‐protein α... 
GPCR | protein phosphorylation | heterotrimeric G proteins | Gα15/16 | phospholipase C‐β (PLC‐β) | Phospholipase C-β (PLC-β) | Protein phosphorylation | Heterotrimeric G proteins
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15. Full Text The C Domain of Netrin UNC-6 Silences Calcium/Calmodulin-Dependent Protein Kinase- and Diacylglycerol-Dependent Axon Branching in Caenorhabditis elegans
by Wang, Qun and Wadsworth, William G
Journal of Neuroscience, ISSN 0270-6474, 03/2002, Volume 22, Issue 6, pp. 2274 - 2282
Second messenger systems mediate neuronal responses to extracellular factors that elicit axon branching, turning, and guidance. We found that mutations in... 
Phospholipase Cβ | UNC-6 | Netrin | Gqα | G-protein subunit | Neuropeptide Y receptor | Diacylglycerol kinase | PLCβ | Calcium/calmodulin-dependent protein kinase | DAK | Guidance | Caenorhabditis elegans | CaMKII | Axon branching | Genetics | RECEPTOR | axon branching | genetics | PLC beta | neuropeptide Y receptor | G(Q)ALPHA | phospholipase beta | calcium/calmodulin-dependent protein kinase | MUTATIONS | MIGRATIONS | netrin | GROWTH CONE GUIDANCE | diacylglycerol kinase | NERVE GROWTH | NEUROSCIENCES | Gq alpha | guidance | IN-VIVO | TISSUE INHIBITOR | SYNAPTIC TRANSMISSION | BINDING | Protein Subunits | Helminth Proteins - pharmacology | Receptors, Neuropeptide Y - metabolism | Type C Phospholipases - metabolism | Heterotrimeric GTP-Binding Proteins - metabolism | Axons - physiology | Nerve Growth Factors - metabolism | Phospholipase C beta | Diglycerides - pharmacology | Isoenzymes - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 | Helminth Proteins - metabolism | Motor Neurons - drug effects | Caenorhabditis elegans Proteins | Animals, Genetically Modified | Diacylglycerol Kinase - metabolism | Axons - drug effects | Helminth Proteins - genetics | Nerve Tissue Proteins | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Netrins | Motor Neurons - metabolism | Animals | Receptors, Neuropeptide Y - genetics | Signal Transduction - drug effects | GTP-Binding Protein alpha Subunits, Gq-G11 | Alleles | Second Messenger Systems - physiology | Signal Transduction - physiology | Mutation | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Protein Structure, Tertiary - physiology
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16. Full Text Phospholipase C beta 1 expression in the dorsolateral prefrontal cortex from patients with schizophrenia at different stages of illness
by Udawela, Madhara and Scarr, Elizabeth and Hannan, Anthony J and Thomas, Elizabeth A and Dean, Brian
Australian and New Zealand Journal of Psychiatry, ISSN 0004-8674, 02/2011, Volume 45, Issue 2, pp. 140 - 147
Objective: Our recent microarray study detected decreases in the expression of phospholipase C beta 1 mRNA in the dorsolateral prefrontal cortex from subjects... 
post-mortem brain tissue | phospholipase C beta 1 (PLC β?1) | schizophrenia | dorsolateral prefrontal cortex | PROTEIN-KINASE-C | PI-PLC ACTIVITY | IMMUNOREACTIVITY | PSYCHIATRY | phospholipase C beta 1 (PLC beta 1) | POSTMORTEM FRONTAL-CORTEX | MICROARRAY ANALYSIS | BRAIN CORTICAL MEMBRANES | MESSENGER-RNA | GENE-EXPRESSION | DOPAMINE | RAT-BRAIN | Schizophrenia - diagnosis | Gene Expression Regulation - genetics | Humans | Middle Aged | Adult | Female | Male | Schizophrenia - enzymology | Cyclophilin A - biosynthesis | Phospholipase C beta - biosynthesis | Prefrontal Cortex - enzymology | Isoenzymes - biosynthesis
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17. Full Text The effect of the farnesyl protein transferase inhibitor SCH66336 on isoprenylation and signalling by the prostacyclin receptor
by O'Meara, Sarah J and Kinsella, B. Therese
Biochemical Journal, ISSN 0264-6021, 02/2005, Volume 386, Issue 1, pp. 177 - 189
Like Ras, farnesylation of the IP (prostacyclin receptor) is required for its efficient intracellular signalling, and hence the IP represents a potential... 
Thromboxane A | Desensitization | Farnesyl protein transferase inhibitor | Prostacyclin receptor | Ras | Isoprenylation | CELLS | ANGIOGENESIS | N-RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | prostacyclin receptor | desensitization | CANCER-THERAPY | FARNESYLTRANSFERASE INHIBITORS | IN-VITRO | HA-RAS | PRENYLATION | GROWTH | thromboxane A | isoprenylation | farnesyl protein transferase inhibitor | Propanolamines - metabolism | Proline - metabolism | Humans | Alkyl and Aryl Transferases - antagonists & inhibitors | HSP40 Heat-Shock Proteins | Iloprost - metabolism | Receptors, Adrenergic, beta-2 - drug effects | Organophosphorus Compounds - metabolism | Recombinant Fusion Proteins - metabolism | Kidney | Dose-Response Relationship, Drug | Transfection | Piperidines - pharmacology | Protein Processing, Post-Translational - drug effects | Proto-Oncogene Proteins p21(ras) - chemistry | Receptors, Thromboxane A2, Prostaglandin H2 - drug effects | Epoprostenol - pharmacology | Cell Line, Tumor - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Cell Line | Protein Prenylation - drug effects | Receptors, Epoprostenol - metabolism | Mutagenesis, Site-Directed | Proline - analogs & derivatives | Receptors, Adrenergic, beta-2 - genetics | Endocytosis - drug effects | Heat-Shock Proteins - metabolism | Adrenergic beta-Agonists - pharmacology | Farnesyltranstransferase | Amino Acid Motifs | Epoprostenol - analogs & derivatives | Animals | Carrier Proteins - metabolism | Cyclic AMP - biosynthesis | Signal Transduction - drug effects | Calcium Signaling - drug effects | Leukemia, Erythroblastic, Acute - pathology | Isoproterenol - pharmacology | Mice | Pyridines - pharmacology | Receptors, Epoprostenol - drug effects | HEL, human erythroleukaemia | N-Ras, neuronal Ras | Ki-Ras, Kirsten Ras | HEK, human embryonic kidney | β2AR, β2 adrenergic receptor | GGPP, geranylgeranyl pyrophosphate | thromboxane A2 | GPCR, G-protein-coupled receptor | FPP, farnesyl pyrophosphate | PLCβ, phospholipase Cβ | Ha-Ras, Harvey Ras | MVA, mevalonolactone | GGTase, geranylgeranyl protein transferase | fura 2 | AM, fura 2 acetoxymethyl ester | FBS, fetal bovine serum | FTI, farnesyl protein transferase inhibitor | LDH, lactate dehydrogenase | PKA, cAMP-dependent protein kinase | [Ca2+]i, intracellular calcium | FTase, farnesyl protein transferase | HA, haemagglutinin | mouse) prostacyclin receptor | m)IP, (human | TXA2, thromboxane A2 | TP, prostanoid TXA2 receptor
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18. Full Text Protein kinase Cα modulates depolarizaton-evoked changes of intracellular Ca 2+ concentration in a rat pheochromocytoma cell line
by Fontainhas, A.M and Obukhov, A.G and Nowycky, M.C
Neuroscience, ISSN 0306-4522, 2005, Volume 133, Issue 2, pp. 393 - 403
Conventional protein kinase C (cPKC) isoforms are activated by a coincident rise in cytosolic Ca and membrane-bound diacylglycerol. In excitable cells, cPKC... 
conventional protein kinase C | YFP | voltage-gated Ca 2+ channels | PKCα tagged with yellow fluorescent protein | intracellular Ca 2+ concentration | pheochromocytoma cells | [Ca 2+] i | PKC | cPKC | DAG | phospholipase C-β | PC12 cells | PLCβ | PC12 | fura-2 | depolarization | yellow fluorescent protein | VGCC | diacylglycerol | protein kinase C | PKCα-YFP
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