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European Journal of Immunology, ISSN 0014-2980, 05/2009, Volume 39, Issue 5, pp. 1369 - 1378
DC recognize microbial components through an array of receptors known as PRR. PRR initiate intracellular signals, which engender DC with the capacity to... 
Dectin‐1 | Signaling | PLCg | PLCγ | Dectin-1
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2018, Volume 505, Issue 2, pp. 569 - 577
The metastatic potential of malignant tumor has been shown to be correlated with the increased expression of tri- and tetra-antennary β1,6-N-acetylglucosamine... 
N-acetylglucosaminyltransferase V | Gliomas | Invasive | PLC-γ | Receptor protein tyrosine phosphatase type μ(RPTP μ)
Journal Article
Molecular medicine reports, 01/2018, Volume 17, Issue 1, p. 898
The aim of the current study was to investigate the role of phospholipase C (PLC)γ/protein kinase C (PKC)/C‑kinase‑activated protein phosphatase‑1 (CPI‑17)... 
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 03/2019, Volume 366, pp. 46 - 53
The classical mast cells degranulation pathway is mediated by FcεRI aggregation and varies in strength among subjects. Dehydroandrographolide (DA) is one of... 
Degranulation | Mast cells | IgE-mediated anaphylactic reactions | P-PLCγ inhibitor | Dehydroandrographolide | NEES | ACTIVATION | ANDROGRAPHIS-PANICULATA | P-PLC gamma inhibitor | ALLERGY | CHRONIC URTICARIA | GROWTH | PHARMACOLOGY & PHARMACY | TOXICOLOGY | EXPRESSION | PHOSPHOLIPASE C-GAMMA | Immunoglobulin E | Histamine | Index Medicus
Journal Article
Neuroscience, ISSN 0306-4522, 2009, Volume 164, Issue 2, pp. 507 - 519
Abstract GABAA receptors composed of the γ2 and δ subunits have distinct properties, functions and subcellular localization, and pathological conditions... 
Neurology | biotinylation assay | internalization | PKC | PLCγ | hippocampus | ligand-gated ion channels
Journal Article
Life Sciences, ISSN 0024-3205, 12/2019, Volume 239, p. 117079
Cutaneous neurofibroma (cNF), a hallmark feature of neurofibromatosis type 1 (NF1), results in psychological and physical damage to patients. Considering the... 
Inflammatory activity | PLCγ | Mast cell | Cutaneous neurofibroma | AKT/IκBα/p65 signaling | MEDICINE, RESEARCH & EXPERIMENTAL | PHOSPHOLIPASE C | INNATE | RECEPTOR | PHARMACOLOGY & PHARMACY | NF1(+/-) | SCHWANN-CELLS | TYPE-1 | AKT/I kappa B alpha/p65 signaling | NF-KAPPA-B | PLC gamma
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 08/2018, Volume 292, pp. 110 - 120
Roxarsone is an organoarsenic feed additive used in livestock and poultry production that is released into the environment, where it poses a risk to human... 
Angiogenesis | B16-F10 xenograft model | Vascular endothelial cells | Roxarsone | PLCγ/PKC signaling | ACTIVATION | SOILS | ARSENIC EXPOSURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLC-GAMMA | PLC gamma/PKC signaling | GROWTH | CHICKEN | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2009, Volume 420, Issue 3, pp. 345 - 361
RTKs (receptor tyrosine kinases) play important roles in cellular proliferation and different liation. In addition, RTKs reveal oncogenic potential when their... 
Extracellular-signal-regulated kinase (ERK) | Pleiotrophin | Anaplastic large cell lymphoma (ALCL) | Neuroblastoma | Non-small cell lung cancer (NSLCL) | Midkine | Anaplastic lymphoma kinase (ALK) | Inflammatory myofibroblastic tumour (IMT) | inflammatory myofibroblastic tumour (IMT) | GROWTH-FACTOR PLEIOTROPHIN | non-small cell lung cancer (NSLCL) | BIOCHEMISTRY & MOLECULAR BIOLOGY | anaplastic lymphoma kinase (ALK) | EML4-ALK FUSION GENE | neuroblastoma | LARGE-CELL LYMPHOMA | HUMAN BREAST-CANCER | extracellular-signal-regulated kinase (ERK) | TFG-ALK TRANSLOCATIONS | pleiotrophin | NEUROTROPHIC FACTOR HBNF | INFLAMMATORY MYOFIBROBLASTIC TUMOR | NON-HODGKINS-LYMPHOMA | midkine | anaplastic large cell lymphoma (ALCL) | GASTROINTESTINAL STROMAL TUMORS | RECEPTOR TYROSINE KINASE | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Oncogene Proteins, Fusion - metabolism | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Protein-Tyrosine Kinases - metabolism | Humans | Lung Neoplasms - metabolism | Neuroblastoma - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Lung Neoplasms - pathology | Nuclear Proteins - metabolism | Receptor Protein-Tyrosine Kinases | Protein-Tyrosine Kinases - genetics | Models, Biological | Oncogene Proteins, Fusion - genetics | Lymphoma, Large-Cell, Anaplastic - pathology | Neuroblastoma - metabolism | Nuclear Proteins - genetics | Lymphoma, Large-Cell, Anaplastic - metabolism | Neuroblastoma - pathology | Lymphoma, Large-Cell, Anaplastic - genetics | ALK, anaplastic lymphoma kinase | LTK, leucocyte tyrosine kinase | MUC-1, mucin-1 | IRS-1, IR substrate-1 | PTN, pleiotrophin | TGFβ, transforming growth factor β | ERK, extracellular-signal-regulated kinase | PKB, protein kinase B | Shc, Src homology and collagen homology | TPM, tropomyosin | IMP cyclohydrolase | MK, midkine | MYH9, non-muscle myosin heavy chain | MAM, meprin, A5 protein and receptor protein tyrosine phosphatase mu | NPM, nucleophosmin | mTOR, mammalian target of rapamycin | NIPA, nuclear interacting partner of ALK | RPTP, receptor protein tyrosine phosphatase | DLBCL, diffuse large B-cell lymphoma | FOXO3a, forkhead box O 3a | NF-κB, nuclear factor κB | Shp1, SH2 domain-containing phosphatase 1 | RANBP2, Ran-binding protein 2 | ALCL, anaplastic large cell lymphoma | Dpp, decapentaplegic | FRS2, fibroblast growth factor receptor substrate 2 | LDLa, low-density lipoprotein class A | EGFR, epidermal growth factor receptor | SEC31L1, SEC31 homologue A | GIST, gastrointestinal stromal tumour | RTK, receptor tyrosine kinase | SH2, Src homology 2 | TFG, TRK-fused gene | ATIC, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase | CLTC, clathrin heavy chain | MAPK, mitogen-activated protein kinase | Hen-1, hesitation-1 | MEK, MAPK | PI3K, phosphoinositide 3-kinase | HEK, human embryonic kidney | SCD-2, suppressor of constitutive dauer 2 | Review | EBPβ, CCAAT | CARS, cysteinyl-tRNA synthetase | JNK, c-Jun N-terminal kinase | ERK kinase | Grb2, growthfactor-receptor-bound protein 2 | SCC, squamous cell carcinoma | EML4, echinoderm microtubule-associated protein like 4 | SHH, sonic hedghog | BCR-Abl, breakpoint cluster region-Abl | IR, insulin receptor | ALO17, ALK lymphoma oligomerization partner on chromosome 17 | enhancer-binding protein β | PLCγ, phospholipase Cγ | NSCLC, non-small cell lung cancer | UCN-01, unco-ordinated 1 | Cdc42, cell division cycle 42 | STAT, signal transducer and activator of transcription | DRG, dorsal root ganglia | MSN, moesin | dALK, Drosophila ALK | IL-3, interleukin-3 | CNS, central nervous system | JAK, Janus kinase | CML, chronic myeloid leukaemia | Jeb, jelly belly | IMT, inflammatory myofibroblastic tumour | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICIN | MEDICINE
Journal Article
Life Sciences, ISSN 0024-3205, 04/2019, Volume 222, pp. 29 - 35
Recently, several plexins and semaphorins have been associated with osteoclastogenesis, a vital process for bone remodeling. Plexin-A2 is implicated in bone... 
Osteoclastogenesis | PLCγ | NFATc1 | Plexin-A2 | Sema6A | MEDICINE, RESEARCH & EXPERIMENTAL | LAMINA-RESTRICTED PROJECTION | PHARMACOLOGY & PHARMACY | BONE | DIFFERENTIATION | EXPRESSION | PLC gamma | SEMAPHORINS | Bone remodelling | Therapeutic applications | Immunoglobulin G | Homeostasis | Activation | Pharmacology | Bone turnover | Osteolysis | Lysates | Semaphorins | Biocompatibility | Osteoclasts | Bone | TRANCE protein
Journal Article
Brain Research, ISSN 0006-8993, 2011, Volume 1377, pp. 32 - 40
Papaverine, an inhibitor of phosphodiesterase (PDE) 10A, is gaining attention for its potential in the treatment of neuropsychiatric diseases such as... 
PDE10A | Papaverine | Neurite outgrowth | PC12 cells | PLC-γ | IP 3 receptors | receptors
Journal Article
Insect Molecular Biology, ISSN 0962-1075, 08/2010, Volume 19, Issue 4, pp. 553 - 566
Sex pheromone production for most moths is regulated by pheromone biosynthesis activating neuropeptide (PBAN). In Bombyx mori, PBAN binding triggers the... 
sex pheromone biosynthesis | phospholipase C | RNAi | signal transduction cascade | PLCγ | PBAN | Bombyx mori | pheromone glands
Journal Article