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Science Signaling, ISSN 1945-0877, 09/2017, Volume 10, Issue 495, p. eaap8372
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2009, Volume 420, Issue 3, pp. 345 - 361
RTKs (receptor tyrosine kinases) play important roles in cellular proliferation and different liation. In addition, RTKs reveal oncogenic potential when their... 
Extracellular-signal-regulated kinase (ERK) | Pleiotrophin | Anaplastic large cell lymphoma (ALCL) | Neuroblastoma | Non-small cell lung cancer (NSLCL) | Midkine | Anaplastic lymphoma kinase (ALK) | Inflammatory myofibroblastic tumour (IMT) | inflammatory myofibroblastic tumour (IMT) | GROWTH-FACTOR PLEIOTROPHIN | non-small cell lung cancer (NSLCL) | BIOCHEMISTRY & MOLECULAR BIOLOGY | anaplastic lymphoma kinase (ALK) | EML4-ALK FUSION GENE | neuroblastoma | LARGE-CELL LYMPHOMA | HUMAN BREAST-CANCER | extracellular-signal-regulated kinase (ERK) | TFG-ALK TRANSLOCATIONS | pleiotrophin | NEUROTROPHIC FACTOR HBNF | INFLAMMATORY MYOFIBROBLASTIC TUMOR | NON-HODGKINS-LYMPHOMA | midkine | anaplastic large cell lymphoma (ALCL) | GASTROINTESTINAL STROMAL TUMORS | RECEPTOR TYROSINE KINASE | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Oncogene Proteins, Fusion - metabolism | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Protein-Tyrosine Kinases - metabolism | Humans | Lung Neoplasms - metabolism | Neuroblastoma - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Lung Neoplasms - pathology | Nuclear Proteins - metabolism | Receptor Protein-Tyrosine Kinases | Protein-Tyrosine Kinases - genetics | Models, Biological | Oncogene Proteins, Fusion - genetics | Lymphoma, Large-Cell, Anaplastic - pathology | Neuroblastoma - metabolism | Nuclear Proteins - genetics | Lymphoma, Large-Cell, Anaplastic - metabolism | Neuroblastoma - pathology | Lymphoma, Large-Cell, Anaplastic - genetics | ALK, anaplastic lymphoma kinase | LTK, leucocyte tyrosine kinase | MUC-1, mucin-1 | IRS-1, IR substrate-1 | PTN, pleiotrophin | TGFβ, transforming growth factor β | ERK, extracellular-signal-regulated kinase | PKB, protein kinase B | Shc, Src homology and collagen homology | TPM, tropomyosin | IMP cyclohydrolase | MK, midkine | MYH9, non-muscle myosin heavy chain | MAM, meprin, A5 protein and receptor protein tyrosine phosphatase mu | NPM, nucleophosmin | mTOR, mammalian target of rapamycin | NIPA, nuclear interacting partner of ALK | RPTP, receptor protein tyrosine phosphatase | DLBCL, diffuse large B-cell lymphoma | FOXO3a, forkhead box O 3a | NF-κB, nuclear factor κB | Shp1, SH2 domain-containing phosphatase 1 | RANBP2, Ran-binding protein 2 | ALCL, anaplastic large cell lymphoma | Dpp, decapentaplegic | FRS2, fibroblast growth factor receptor substrate 2 | LDLa, low-density lipoprotein class A | EGFR, epidermal growth factor receptor | SEC31L1, SEC31 homologue A | GIST, gastrointestinal stromal tumour | RTK, receptor tyrosine kinase | SH2, Src homology 2 | TFG, TRK-fused gene | ATIC, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase | CLTC, clathrin heavy chain | MAPK, mitogen-activated protein kinase | Hen-1, hesitation-1 | MEK, MAPK | PI3K, phosphoinositide 3-kinase | HEK, human embryonic kidney | SCD-2, suppressor of constitutive dauer 2 | Review | EBPβ, CCAAT | CARS, cysteinyl-tRNA synthetase | JNK, c-Jun N-terminal kinase | ERK kinase | Grb2, growthfactor-receptor-bound protein 2 | SCC, squamous cell carcinoma | EML4, echinoderm microtubule-associated protein like 4 | SHH, sonic hedghog | BCR-Abl, breakpoint cluster region-Abl | IR, insulin receptor | ALO17, ALK lymphoma oligomerization partner on chromosome 17 | enhancer-binding protein β | PLCγ, phospholipase Cγ | NSCLC, non-small cell lung cancer | UCN-01, unco-ordinated 1 | Cdc42, cell division cycle 42 | STAT, signal transducer and activator of transcription | DRG, dorsal root ganglia | MSN, moesin | dALK, Drosophila ALK | IL-3, interleukin-3 | CNS, central nervous system | JAK, Janus kinase | CML, chronic myeloid leukaemia | Jeb, jelly belly | IMT, inflammatory myofibroblastic tumour | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICIN | MEDICINE
Journal Article
Experimental Brain Research, ISSN 0014-4819, 11/2000, Volume 135, Issue 3, pp. 319 - 330
Heparin affin regulatory peptide (HARP), also known as pleiotrophin or heparin-binding growth-associated molecule, is a developmentally regulated extracellular... 
pleiotrophin
Journal Article
Life Sciences, ISSN 0024-3205, 12/2019, Volume 239, p. 116871
Emerging evidence suggests that dysregulation of circular RNAs (circRNAs) closely associated with cancer progression. In this paper, we focus on exploring the... 
Circ-LDLRAD3 | Circular RNA | miR-137-3p | Pancreatic cancer | Pleiotrophin
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 09/2019, Volume 369, p. 111933
Pleiotrophin (PTN) and Midkine (MK) are neurotrophic factors that are upregulated in the prefrontal cortex after alcohol administration and have been shown to... 
ALK | Conditioned place preference | Addiction | Pleiotrophin | Alcohol | Fyn | Midkine
Journal Article
Chinese Journal of Cancer Prevention and Treatment, ISSN 1673-5269, 09/2018, Volume 25, Issue 17, pp. 1211 - 1216
Journal Article
Nature Neuroscience, ISSN 1097-6256, 07/2019, Volume 22, Issue 7, pp. 1041 - 1043
The creation of a murine Cre driver specific to CNS capillary pericytes has opened a major bottleneck in brain microvascular research. Using this tool,... 
ATLAS | GENE-EXPRESSION | NEUROSCIENCES | BRAIN | Pericytes | Brain | Sharpening | Microvasculature | Depletion | Pleiotrophin
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 09/2006, Volume 98, Issue 5, pp. 1497 - 1506
The protein tyrosine phosphatase ζ/receptor‐type protein tyrosine phosphatase β (PTPζ/RPTPβ) and its ligand pleiotrophin (PTN) are overexpressed in human... 
phosphacan | migration | glioma | pleiotrophin | invasion | proliferation | Proliferation | Glioma | Migration | Phosphacan | Invasion | Pleiotrophin
Journal Article
Neuropharmacology, ISSN 0028-3908, 07/2018, Volume 137, pp. 86 - 95
Pleiotrophin (PTN) and Midkine (MK) are neurotrophic factors that are upregulated in the prefrontal cortex after alcohol administration and have been shown to... 
ALK | TrkA | Alcohol use disorder | Binge-drinking | Midkine | Pleiotrophin | alcohol use disorder | pleiotrophin | binge-drinking | midkine
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2014, Volume 37, Issue 4, pp. 511 - 520
Midkine (MK) and pleiotrophin (PTN) belong to the subfamily of heparin binding growth factors. They have ca. 50% structural homology, with similar C- and... 
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 04/2019, Volume 10
Inflammation is a common factor of pathologies such as obesity, type 2 diabetes or neurodegenerative diseases. Chronic inflammation is considered part of the... 
neurodegeneration | PLEIOTROPHIN GENE-EXPRESSION | ANAPLASTIC LYMPHOMA KINASE | EXTRACELLULAR VARIANT | pleiotrophin | GROWTH-FACTOR MIDKINE | neuroinflammation | inflammation | SIGNALING PATHWAY | ADIPOSE-TISSUE PLASTICITY | INSULIN-RESISTANCE | ACTIVATED-RECEPTOR-GAMMA | PPAR-GAMMA | PHARMACOLOGY & PHARMACY | midkine | PTPRZ | aging | obesity | PROTEIN-TYROSINE-PHOSPHATASE
Journal Article
Diabetologia, ISSN 0012-186X, 1/2019, Volume 62, Issue 1, pp. 123 - 135
Journal Article