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Nature, ISSN 0028-0836, 09/2011, Volume 477, Issue 7366, pp. 616 - 622
Journal Article
Oncogene, ISSN 0950-9232, 03/2019, Volume 38, Issue 12, pp. 2177 - 2191
Journal Article
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 06/2006, Volume 396, Issue 3, pp. 419 - 429
PAR [poly(ADP-ribose)] is a structural and regulatory component of multiprotein complexes in eukaryotic cells. PAR catabolism is accelerated under genotoxic... 
APOPTOSIS | RNA interference | NUCLEAR | RAT | DNA damage response | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-methyl-N '-nitro-N-nitrosoguanidine (MNNG) | DNA-DAMAGE | poly(ADP-ribose) glycohydrolase (PARG) | H2O2 | IDENTIFICATION | PARP-1 | silencing | NECROSIS | POLYMERASE-1 | HYDROGEN-PEROXIDE | GALLOTANNIN | Cell Survival - drug effects | Apoptosis - drug effects | Glycoside Hydrolases - physiology | Glycoside Hydrolases - genetics | Humans | Cells, Cultured | Hydrogen Peroxide - pharmacology | Mice, Knockout | Methylnitronitrosoguanidine - pharmacology | Poly Adenosine Diphosphate Ribose - metabolism | Animals | RNA Interference | Mice | HeLa Cells | Index Medicus | MNNG, N-methyl-N′-nitro-N-nitrosoguanidine | RNAi, RNA interference | PI3K, phosphoinositide 3-kinase | PCNA, proliferating-cell nuclear antigen | ADP-HPD, ADP (hydroxymethyl)pyrrolidinediol | DTT, dithiothreitol | DMEM, Dulbecco's modified Eagle's medium | SVPDE, snake venom phosphodiesterase | PARP, PAR polymerase | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | 3-AB, 3-aminobenzamide | N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) | PARG, PAR glycohydrolase | FBS, fetal bovine serum | NLS, nuclear localization signal | ARH3, ADP-ribosyl-(arginine)-hydrolase 3 | siRNA, small interfering RNA | MEF, mouse embryonic fibroblast | DTNB, 5,5′-dithiobis-(2-nitrobenzoic acid) | PAR, poly(ADP-ribose)
Journal Article
Journal Article
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 12/2012, Volume 48, Issue 5, pp. 785 - 798
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 2011, Volume 68, Issue 8, pp. 1455 - 1466
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 08/2019, Volume 79, Issue 15, pp. 3851 - 3861
Poly (ADP-ribose) glycohydrolase (PARG) is the main enzyme responsible for catabolism of poly (ADP-ribose) (PAR), synthesized by PARP. PARG dysfunction... 
REPAIR | PARG | ONCOLOGY | POLY(ADP-RIBOSE) GLYCOHYDROLASE | MUTANT-CELLS | DNA-DAMAGE | MOUSE ES CELLS | INHIBITORS | DEFICIENCY | DISCOVERY | P53 | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, pp. e0151172 - e0151172
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2014, Volume 452, Issue 3, pp. 708 - 714
Journal Article