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1. Full Text Nano/micro technologies for delivering macromolecular therapeutics using poly( d,l-lactide- co-glycolide) and its derivatives
by Mundargi, Raghavendra C and Babu, V. Ramesh and Rangaswamy, Vidhya and Patel, Pradip and Aminabhavi, Tejraj M
Journal of Controlled Release, ISSN 0168-3659, 2008, Volume 125, Issue 3, pp. 193 - 209
Biodegradable nano/microparticles of poly( -lactide- -glycolide) (PLGA) and PLGA-based polymers are widely explored as carriers for controlled delivery of... 
Nanoparticles | Proteins | Targeted drug delivery | PLGA | Peptides | Microparticles | GENE DELIVERY | CELLS IN-VITRO | DRUG-DELIVERY | microparticles | targeted drug delivery | peptides | BIODEGRADABLE TRIBLOCK COPOLYMER | CHEMISTRY, MULTIDISCIPLINARY | OF-THE-ART | POLY(LACTIDE-CO-GLYCOLIDE) MICROSPHERES | nanoparticles | POLYMERIC NANOPARTICLES | PLGA-PEG-PLGA | proteins | PHARMACOLOGY & PHARMACY | LOADED NANOPARTICLES | PROTEIN DELIVERY | Particle Size | Lactic Acid - chemistry | Drug Carriers - therapeutic use | Nanotechnology - methods | Polyglycolic Acid - chemistry | Pharmaceutical Preparations - chemistry | Polymers - chemistry | Molecular Structure | Drug Carriers - chemistry | Drug Delivery Systems | Drugs | Drug delivery systems | Vehicles
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2. Full Text Biodegradable self-assembled nanoparticles of poly ( d , l -lactide-co-glycolide)/hyaluronic acid block copolymers for target delivery of docetaxel to breast cancer
by Huang, Jingbin and Zhang, He and Yu, Yuan and Chen, Yan and Wang, Dong and Zhang, Guoqing and Zhou, Guichen and Liu, Junjie and Sun, Zhiguo and Sun, Duxin and Lu, Ying and Zhong, Yanqiang
Biomaterials, ISSN 0142-9612, 2013, Volume 35, Issue 1, pp. 550 - 566
Abstract To develop biodegradable docetaxel-loaded self-assembled nanoparticles of poly ( d , l -lactide-co-glycolide)/hyaluronic acid block copolymers were... 
Advanced Basic Science | Dentistry | Poly (d,l-lactide-co-glycolide) | Breast cancer | Self-assembled nanoparticles | Hyaluronic acid | CD44 | Docetaxel | CELLS | MATERIALS SCIENCE, BIOMATERIALS | MOLECULAR-WEIGHT | GENE DELIVERY | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | DOXORUBICIN | MICELLES | Poly (D,L-lactide-co-glycolide) | HYALURONIC-ACID | CELLULAR UPTAKE | PACLITAXEL | CYTOTOXICITY | Breast Neoplasms - immunology | Humans | Molecular Sequence Data | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Drug Carriers | Nanoparticles | Taxoids - therapeutic use | Flow Cytometry | Female | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Carbohydrate Sequence | Hyaluronic Acid - administration & dosage | Lactic Acid - chemistry | Hyaluronic Acid - chemistry | Rats | Breast Neoplasms - drug therapy | Rats, Sprague-Dawley | Taxoids - administration & dosage | Animals | Breast Neoplasms - pathology | Polyglycolic Acid - chemistry | Cell Line, Tumor | Biocompatible Materials | Hyaluronan Receptors - immunology | Mice | Mice, Inbred BALB C | Antimitotic agents | Chemotherapy | Drugstores | Antineoplastic agents | Block copolymers | Cancer | Index Medicus
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3. Full Text Ethylenediamine assisted functionalization of self-organized poly (d, l-lactide-co-glycolide) patterned surface to enhance cancer cell isolation
by Jaiswal, Namita and Hens, Abhiram and Chatterjee, Manosree and Mahata, Nibedita and Chanda, Nripen
Journal of Colloid And Interface Science, ISSN 0021-9797, 01/2019, Volume 534, pp. 122 - 130
Protein functionalized micro-scale patterned structures are developed using a biocompatible polymer PLGA (poly ( , -lactide-co-glycolide)) via thin film... 
Patterned surface | Ethylenediamine | Functionalization | Antibody | Cancer cell isolation | poly (d, l-lactide-co-glycolide) | Dewetting | poly (D, L-lactide-co-glycolide) | THIN-FILMS | INSTABILITY | CHEMISTRY, PHYSICAL | ANTIBODY IMMOBILIZATION | AMINOLYSIS | HUMAN ENDOTHELIAL-CELLS | PROTEIN NANOARRAYS | CIRCULATING TUMOR-CELLS | CYTOCOMPATIBILITY | POLY(ETHYLENE-TEREPHTHALATE) | CAPTURE | Epithelial Cell Adhesion Molecule - immunology | Humans | Polylactic Acid-Polyglycolic Acid Copolymer - chemistry | Cell Line, Tumor | Adult | Neoplastic Cells, Circulating - chemistry | Cell Separation - methods | Neoplastic Cells, Circulating - immunology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Ethylenediamines | Thin films | Viral antibodies | Antibodies | Dielectric films | Mechanical engineering | Cancer
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4. Full Text Residual polyvinyl alcohol associated with poly ( d, l-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake
by Sahoo, Sanjeeb K and Panyam, Jayanth and Prabha, Swayam and Labhasetwar, Vinod
Journal of Controlled Release, ISSN 0168-3659, 2002, Volume 82, Issue 1, pp. 105 - 114
Polyvinyl alcohol (PVA) is the most commonly used emulsifier in the formulation of poly lactide and poly (D,L-lactide-co-glycolide) (PLGA) polymeric... 
Sustained release | Particle size | Intracellular uptake | Polyvinyl alcohol | Hydrophobicity | particle size | PHAGOCYTOSIS | ACID) NANOPARTICLES | MICROSPHERES | sustained release | DRUG-DELIVERY | intracellular uptake | POLY(VINYL ALCOHOL) | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | hydrophobicity | polyvinyl alcohol | BIODEGRADABLE MICROPARTICLES | NANOSPHERES | PHARMACOLOGY & PHARMACY | PARTICLE-SIZE | SMOOTH-MUSCLE CELLS | Polyvinyl Alcohol - chemistry | Lactic Acid - chemistry | Biocompatible Materials - chemistry | Humans | Phagocytosis - physiology | Muscle, Smooth, Vascular - cytology | Drug Carriers - chemistry | Particle Size | Excipients - chemistry | Polyglycolic Acid - chemistry | Surface Properties | Polymers - chemistry | Serum Albumin, Bovine - chemistry | Nanotechnology
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5. Full Text Controlled-release of tetracycline and lovastatin by poly(D,L-lactide-co-glycolide acid)-chitosan nanoparticles enhances periodontal regeneration in dogs
by Lee, Bor-Shiunn and Lee, Chien-Chen and Wang, Yi-Ping and Chen, Hsiao-Jan and Lai, Chern-Hsiung and Hsieh, Wan-Ling and Chen, Yi-Wen
International Journal of Nanomedicine, ISSN 1176-9114, 01/2016, Volume 11, pp. 285 - 297
Chronic periodontitis is characterized by inflammation of periodontal tissues, leading to bone resorption and tooth loss. The goal of treatment is to... 
Periodontal regeneration | Lovastatin | Chitosan | Poly(D,L-lactide-co-glycolide acid) | Tetracycline | chitosan | ALVEOLAR BONE | MICROSPHERES | RANDOMIZED CLINICAL-TRIAL | NANOSCIENCE & NANOTECHNOLOGY | poly(D,L-lactide-co-glycolide acid) | LOCAL-DRUG DELIVERY | periodontal regeneration | IN-VITRO | THERAPY | PLGA | SUBGINGIVALLY DELIVERED SIMVASTATIN | DISEASE | DEGRADATION | PHARMACOLOGY & PHARMACY | tetracycline | lovastatin | Bone Regeneration - drug effects | Microscopy, Electron, Transmission | Lactic Acid - chemistry | Lovastatin - pharmacology | Nanoparticles - chemistry | Osteoblasts - drug effects | Tetracycline - chemistry | Tetracycline - pharmacology | Alkaline Phosphatase - metabolism | Bacteria - drug effects | Lovastatin - chemistry | Drug Carriers - administration & dosage | Male | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Animals | Chitosan - chemistry | Polyglycolic Acid - chemistry | Dogs | Anti-Bacterial Agents - pharmacology | Lovastatin - administration & dosage | Nanoparticles - administration & dosage | Osteoblasts - cytology | Tetracycline - administration & dosage | Nanoparticles | Infection control | Antilipemic agents | Drug delivery systems | Fourier transforms | Particle size | Hydrogels | Clinical trials | Alcohol | Systematic review | Dentistry | Molecular weight | Defects | Biomedical materials | Acids | Antibiotics | Spectrum analysis | Diabetes | Polymers
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6. Full Text Sustained release of strontium (Sr2+) from polycaprolactone/poly (D,L-lactide-co-glycolide)-polyvinyl alcohol coaxial nanofibers enhances osteoblastic differentiation
by Chen, Liang and Mazeh, Hanan and Guardia, Angelica and Song, Wei and Begeman, Paul and Markel, David C and Ren, Weiping
Journal of Biomaterials Applications, ISSN 0885-3282, 10/2019, Volume 34, Issue 4, pp. 533 - 545
Electrospun nanofibers mimic the bone’s extra-cellular matrix and represent an alternative implant coating to enhance implant osseointegration. Approximately... 
VITRO | MATERIALS SCIENCE, BIOMATERIALS | Coaxial nanofibers | ENGINEERING, BIOMEDICAL | IN-VIVO DEGRADATION | strontium | OSSEOINTEGRATION | PROLIFERATION | osteogenesis | L-lactide-co-glycolide) (PLGA | PHOSPHATE | PLGA | RANELATE | drug release | BONE | SCAFFOLDS | poly (D | SURFACES
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7. Full Text Synthesis and characterization of poly(d,l-lactide-co-glycolide) modified by maleic anhydride and 1,4-butanediamine
by Zhang, Qiao and Fang, Jianjun and Liu, Wenjuan and Zhao, Yunhui and Huang, Tianlong and Cui, Jiale and Yang, Yun and Zhou, Zhihua
International Journal of Polymer Analysis and Characterization, ISSN 1023-666X, 07/2018, Volume 23, Issue 5, pp. 474 - 482
Bone tissue engineering is sought to apply strategies for bone defects healing biodegradable porous scaffolds without limitations and shortcomings. In this... 
maleic anhydride | 1,4-butanediamine | Poly(lactide-co-glycolide) | modification | POLYMER SCIENCE | DRUG-DELIVERY | POLY(LACTIC-CO-GLYCOLIC ACID) | FABRICATION | COMPOSITES | SCAFFOLDS | BIOLOGICAL-PROPERTIES | COPOLYMER | Anhydrides | Fourier transformation | Fourier transforms | Nuclear magnetic resonance--NMR | Tissue engineering | Toxicity | Biodegradability | Liquid chromatography | Contact angle | Maleic anhydride | Biomedical materials | Hydrophilicity | Morphology | Biocompatibility | Polymers | Chemical synthesis
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8. Full Text Fabrication of electrospun poly(D,L lactide-co-glycolide)80/20 scaffolds loaded with diclofenac sodium for tissue engineering
by Nikkola, L and Morton, T and Balmayor, ER and Jukola, H and Harlin, A and Redl, H and van Griensven, M and Ashammakhi, N
EUROPEAN JOURNAL OF MEDICAL RESEARCH, ISSN 0949-2321, 06/2015, Volume 20, Issue 1, pp. 54 - 54
Background: Adaptation of nanotechnology into materials science has also advanced tissue engineering research. Tissues are basically composed of nanoscale... 
Drug release | MEDICINE, RESEARCH & EXPERIMENTAL | Poly(D,L lactide-co-glycolide) | DEXAMETHASONE | Biodegradable | ACID | Electrospinning | Diclofenac sodium | Scaffold | RELEASE | ULTRAFINE FIBERS | DELIVERY | Nanofibers - chemistry | Diclofenac - pharmacology | Tissue Engineering - methods | Tissue Scaffolds - adverse effects | Nanofibers - adverse effects | Diclofenac - chemistry | Tissue Scaffolds - chemistry | Animals | Fibroblasts - drug effects | Drug Liberation | Mice | Polyglactin 910 - chemistry | Polyglactin 910 - pharmacology | 3T3 Cells | Biological products | Polymers | Tissue engineering | Nanotechnology | Diclofenac | Index Medicus
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9. Full Text Study on Direct Grafting Maleic Anhydride onto Poly(D,L-lactide-co-glycolide) Chains
by Bai, Shan and Ouyang, Zhenzhong
Journal of Macromolecular Science, Part B, ISSN 0022-2348, 12/2017, Volume 56, Issue 11-12, pp. 853 - 862
Direct graft copolymerization of maleic anhydride (MAH) onto poly(D,L-lactide-co-glycolide) (PLGA) was performed by use of benzoyl peroxide (BPO) as initiator.... 
maleic anhydride | Degree of maleation | direct graft copolymerization | poly(D,L-lactide-co-glycolide) | BIOACTIVE GLASS | DESIGN | POLYMER SCIENCE | ACID | poly(D | L-lactide-co-glycolide | PLGA MICROSPHERES | POROUS SCAFFOLDS | EXTRUSION | Fourier transformation | Temperature | Fourier transforms | Graft copolymers | Nuclear magnetic resonance--NMR | Chains | Copolymerization | Contact angle | Infrared spectra | Infrared analysis | Sodium chloride | Monomers | Maleic anhydride | Polylactide-co-glycolide | Peroxide | Benzoyl peroxide | Titration
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10. Full Text Preparation of histone deacetylase inhibitor vorinostat-loaded poly D, L-lactide-co-glycolide polymeric nanoparticles by nanoprecipitation method
by Ravikumar, Vilwanathan and Sankar, Renu
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1510, pp. 399 - 403
Nanotechnology is a comparatively new branch of science that includes harnessing the unique properties of particles that are nanometers in scale. Nanoparticles... 
L-lactide-co-glycolide | Poly D | Nanoprecipitation | Surfactants | Vorinostat | Particle Size | Lactic Acid - chemistry | Nanoparticles - chemistry | Polysorbates - chemistry | Solutions | Drug Compounding - methods | Humans | Nanoparticles - metabolism | Polyglycolic Acid - chemistry | Hydroxamic Acids - chemistry | Surface-Active Agents - chemistry | Histone Deacetylase Inhibitors - chemistry
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11. Full Text Anovel paclitaxel-loaded poly(D,L-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment
by Yuan, Xun and Ji, Wenxiang and Chen, Si and Bao, Yuling and Tan, Songwei and Lu, Shun and Wu, Kongming and Chu, Qian
International Journal of Nanomedicine, ISSN 1176-9114, 05/2016, Volume 11, pp. 2119 - 2131
Poly(D, L-lactide-co-glycolide) | Drug resistance | Nanoparticle | Lung cancer | Tween 80
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12. Full Text Synthesis, characterization, and degradation behaviors of poly(D,L-lactide-co-glycolide) modified by maleic anhydride and ethanediamine
by Cui, Jiale and Zhou, Zhihua and Yang, Yun and Liu, Wenjuan and Zhao, Yunfei and Peng, Cheng and Huang, Tianlong and Zhou, Hu and Liu, Lihua and Zhang, Qiao
International Journal of Polymer Analysis and Characterization, ISSN 1023-666X, 10/2017, Volume 22, Issue 7, pp. 575 - 586
In order to improve hydrophilicity and settle the acidity in hydrolysis, a novel ethanediamine (EDA) and maleic anhydride (MAH) modified... 
maleic anhydride | ethanediamine | Degradation in vitro | modification | poly(D,L-lactide-co-glycolide) | POLYMER SCIENCE | ACID | PLA | POLY-L-LACTIDE | MECHANICAL-PROPERTIES | DELIVERY | FUNCTIONALIZATION | REACTIVE EXTRUSION | WEIGHT | MALEATION | COPOLYMER | Ring opening polymerization | Fourier transformation | Fourier transforms | Nuclear magnetic resonance--NMR | Polymerization | Fuel consumption | Liquid chromatography | Contact angle | Maleic anhydride | Degradation | Hydrophilicity | Infrared spectrometers | Polydispersity | Titration | Chemical synthesis
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13. Full Text Preparation and Properties of Novel Maleated Poly (D, L-lactide-co-glycolide) Porous Scaffolds for Tissue Engineering
by Zhang, Qiao and Zhou, Zhihua and Peng, Cheng and Huang, Tianlong and Liu, Wenjuan and Liu, Qingquan and Zhou, Hu and Wang, Wei and Yan, Hua
Journal of Macromolecular Science, Part B, ISSN 0022-2348, 07/2017, Volume 56, Issue 7, pp. 505 - 515
Three-dimensional biodegradable porous scaffolds play an important role in tissue engineering. A new polymer based on maleated poly(lactic-co-glycolic acid)... 
scaffold | poly(lactic-co-glycolic acid) | Maleic anhydride | BIOMATERIAL | MALEIC-ANHYDRIDE | DESIGN | POLYMER SCIENCE | ACID | RELEASE | BONE | Biodegradation | Salts | Tissue engineering | Biodegradability | Copolymerization | Compressive strength | Leaching | Monomers | Polylactide-co-glycolide | Engineering | Glycolic acid | Porosity | Chemical synthesis | Scaffolds | Direct melting
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14. Full Text Polymer degradation and in vitro release of a model protein from poly( d, l-lactide- co-glycolide) nano- and microparticles
by Panyam, Jayanth and Dali, Manisha M and Sahoo, Sanjeeb K and Ma, Wenxue and Chakravarthi, Sudhir S and Amidon, Gordon L and Levy, Robert J and Labhasetwar, Vinod
Journal of Controlled Release, ISSN 0168-3659, 2003, Volume 92, Issue 1, pp. 173 - 187
The objective of the study was to investigate the effect of particle size of nano- and microparticles formulated from poly(D,L-lactide-co-glycolide) (50:50... 
Sustained release | Particle size | Drug delivery | Polyvinyl alcohol | Biodegradable polymers | DRUG | particle size | MICROSPHERES | sustained release | biodegradable polymers | STABILIZATION | STABILITY | SIZE | drug delivery | FORMULATION | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | PLGA | polyvinyl alcohol | BIODEGRADABLE MICROPARTICLES | KINETICS | PHARMACOLOGY & PHARMACY | Lactic Acid - pharmacokinetics | Microspheres | Serum Albumin, Bovine - pharmacokinetics | Animals | Lactic Acid - chemistry | Polyglycolic Acid - pharmacokinetics | Cattle | Nanotechnology - methods | Polyglycolic Acid - chemistry | Polymers - pharmacokinetics | Polymers - chemistry | Serum Albumin, Bovine - chemistry | poly(D,L-lactide-co-glycolide)
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15. Full Text A bio-artificial poly([D,L]-lactide-co-glycolide) drug-eluting nanofibrous periosteum for segmental long bone open fractures with significant periosteal stripping injuries
by Chou, Ying-Chao and Cheng, Yi-Shiun and Hsu, Yung-Heng and Yu, Yi-Hsun and Liu, Shih-Jung
International Journal of Nanomedicine, ISSN 1176-9114, 03/2016, Volume 11, pp. 941 - 953
Biodegradable poly([D,L]-lactide-co-glycolide) (PLGA) nanofibrous membrane embedded with two drug-to-polymer weight ratios, namely 1: 3 and 1: 6, which... 
Biodegradable poly([D,L]-lactide-co-glycolide) drug-eluting nanofibers | Polycaprolactone stents | Artificial periosteum | Segmental long bone open fractures | CELLS | artificial periosteum | MANAGEMENT | FLAPS | VIVO | SOFT-TISSUE RECONSTRUCTION | segmental long bone open fractures | NANOSCIENCE & NANOTECHNOLOGY | polycaprolactone stents | biodegradable poly([D,L]-lactide-co-glycolide) drug-eluting nanofibers | IN-VITRO | VANCOMYCIN | EXTREMITY | PHARMACOLOGY & PHARMACY | SUSTAINABLE DELIVERY | Fractures, Open - drug therapy | Nanofibers - chemistry | Lidocaine - pharmacology | Rabbits | Lactic Acid - chemistry | Ceftazidime - pharmacology | Membranes, Artificial | Lidocaine - therapeutic use | Femoral Fractures - pathology | Lidocaine - chemistry | Drug Carriers - chemistry | Vancomycin - chemistry | Animals | Vancomycin - therapeutic use | Periosteum - injuries | Polyglycolic Acid - chemistry | Vancomycin - pharmacology | Ceftazidime - chemistry | Femoral Fractures - drug therapy | Fractures, Open - pathology | Periosteum - drug effects | Ceftazidime - therapeutic use | Polymer blends | Laboratories | Power supply | Bone surgery | Molecular weight | Studies | Airway management | Fractures | Antibiotics | Orthopedics | Amputation | Surgeons | Bones | Growth factors | Injuries
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16. Full Text Fabrication and Use of Poly(d,l-lactide-co-glycolide)-Based Formulations Designed for Modified Release of 5-Fluorouracil
by Leelakanok, Nattawut and Geary, Sean and Salem, Aliasger
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 02/2018, Volume 107, Issue 2, pp. 513 - 528
5-fluorouracil (5-FU) is a chemotherapeutic agent that has been used for the treatment of a variety of malignancies since its initial introduction to the... 
5-fluorouracil | microparticles | nanoparticles | poly(lactic/glycolic) acid (PLGA, PLA) | controlled/sustained release/delivery | 5-FU | CHEMISTRY, MEDICINAL | ANTICANCER DRUG | CHEMISTRY, MULTIDISCIPLINARY | METASTATIC COLORECTAL-CANCER | MALIGNANT GLIOMA | GLAUCOMA DRAINAGE DEVICES | TUMOR-BEARING MICE | CO-GLYCOLIC ACID | PHARMACOLOGY & PHARMACY | DRUG-DELIVERY SYSTEMS | IN-VIVO EVALUATION | SUSTAINED-RELEASE | PLGA NANOPARTICLES | Animals | Chemistry, Pharmaceutical - methods | Lactic Acid - chemistry | Polylactic Acid-Polyglycolic Acid Copolymer | Fluorouracil - chemistry | Humans | Polyglycolic Acid - chemistry | Antimetabolites, Antineoplastic - chemistry | Drug Delivery Systems - methods | Drug Carriers - chemistry | Index Medicus
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