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OncoImmunology, ISSN 2162-4011, 08/2012, Volume 1, Issue 5, pp. 699 - 739
Toll-like receptors (TLRs) are prototypic pattern recognition receptors (PRRs) best known for their ability to activate the innate immune system in response to... 
agatolimod | resiquimod | CpG-7909 | VTX-2337 | TRIF | MYD88 | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | DOUBLE-STRANDED-RNA | POLYADENYLIC-POLYURIDYLIC ACID | POLYRIBOINOSINIC-POLYRIBOCYTIDYLIC ACID | DORSAL-VENTRAL POLARITY | IMMUNE-RESPONSE MODIFIERS | IMMUNOLOGY | PLASMACYTOID DENDRITIC CELLS | PHASE-II TRIAL | POLY-L-LYSINE | ONCOLOGY | TLR9 AGONIST | NF-KAPPA-B | Review
Journal Article
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 2014, Volume 14, Issue 2, pp. 241 - 255
Cancer cells create a microenvironment that prevents tumor rejection by the host's immune system. The activation of pattern recognition receptors (PRRs) can... 
Dendritic cell | Cancer vaccine | Immune response | Tumor associated antigen | Cytokine | Double-stranded RNA | Retinoic acid-inducible gene-I | Inflammasome | Nucleotide-binding domain and leucine-rich repeat containing gene family pyrin domain 3 | Poly (ICLC) | T helper cell | Cross-presentation | Immunotherapy | Immunoediting | Tumor | Adjuvant | Polyinosinic-polycytidylic acid | Cytotoxic T lymphocyte | Melanoma differentiation-associated gene 5 | Poly (I:C12U) | Polyadenylic-polyuridylic acid | Toll-like receptor | DOUBLE-STRANDED-RNA | poly (ICLC) | cancer vaccine | NUCLEIC-ACID | retinoic acid-inducible gene-I | RIG-I | double-stranded RNA | polyadenylic-polyuridylic acid | cross-presentation | immune response | immunotherapy | INNATE IMMUNE SENSOR | OPERABLE BREAST-CANCER | NF-KAPPA-B | cytokine | CHEMISTRY, MEDICINAL | polyinosinic-polycytidylic acid | NLRP3 INFLAMMASOME | nucleotide-binding domain and leucine-rich repeat containing gene family pyrin domain 3 | IFN-REGULATORY FACTOR-3 | TOLL-LIKE RECEPTOR-3 | cytotoxic T lymphocyte | melanoma differentiation-associated gene 5 | ONCOLOGY | inflammasome | tumor | tumor associated antigen | toll-like receptor | poly (I:C12U) | dendritic cell | immunoediting | Adaptive Immunity | Neoplasms - metabolism | Immunotherapy - methods | Signal Transduction | Humans | Combined Modality Therapy | Immunity, Innate | Toll-Like Receptor 3 - metabolism | Receptors, Pattern Recognition - metabolism | Neoplasms - therapy | Immune System - metabolism | Neoplasms - immunology | Immune System - drug effects | Immunotherapy - trends | RNA, Double-Stranded - pharmacology | RNA, Double-Stranded - therapeutic use | Receptors, Pattern Recognition - agonists | RNA, Double-Stranded - metabolism | Apoptosis
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2019, Volume 10, p. 503
An important challenge in cancer immunotherapy is to expand the number of patients that benefit from immune checkpoint inhibitors (CI), a fact that has been... 
DsRNA mimetics | CD103+ cDC1 | Cancer immunotherapy | Tumor-infiltrate | TLR3 | POLYADENYLIC-POLYURIDYLIC ACID | MACROPHAGES | IMMUNOLOGY | CHEMOTHERAPY | ADJUVANT | tumor-infiltrate | B-CELLS | RESPONSES | NK CELLS | CD103(+) cDC1 | cancer immunotherapy | dsRNA mimetics | RESISTANCE | OPERABLE BREAST-CANCER | EXPRESSION
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 10/2015, Volume 1098, pp. 342 - 350
The cooperativity of TMPyP4 ligand binding to Poly(A)-Poly(U) polynucleotide were monitored in this study by fluorescence spectroscopy and UV–Vis absorbance... 
Binding | Cooperativity | TMPyP4 | Poly(A)-Poly(U) | INTERACTIVE AGENTS | POLYADENYLIC-POLYURIDYLIC ACID | HUMAN TUMOR | RNA | PORPHYRINS | C-MYC | CHEMISTRY, PHYSICAL | ANTITUMOR-ACTIVITY | G-QUADRUPLEX DNA | POLYPYRIDYL COMPLEX
Journal Article
Analytica Chimica Acta, ISSN 0003-2670, 1998, Volume 363, Issue 2, pp. 119 - 132
UV-absorption and circular dichroism (CD) spectroscopy have been applied to the study of the acid-base properties of the heteropolynucleotide... 
Acid-base equilibria | Conformational changes | Multivariate curve resolution | Polyadenylic-polyuridylic acid | CHEMISTRY, ANALYTICAL | CURVE RESOLUTION | acid-base equilibria | DNA | COMPLEXES | conformational changes | polyadenylic-polyuridylic acid | multivariate curve resolution | BINDING
Journal Article
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 2013, Volume 4, p. 338
Mounting evidence suggests that imbalances in immune regulation contribute to cell transformation. Women of African descent are an understudied group at high... 
IMMUNITY | single nucleotide polymophism,TLR3 | POLYADENYLIC-POLYURIDYLIC ACID | STIMULATION | INNATE | breast cancer | IRAK4 | PREVALENCE | IMMUNOLOGY | DESCENT | XCT subdomain | innate immunity | extracellular kinase | African-American | MEN | TOLL-LIKE RECEPTORS | RADIOTHERAPY | ASSOCIATION | IRAK-4 | Single nucleotide polymorphism | TLR3 | African American
Journal Article
Journal of Surgical Oncology, ISSN 0022-4790, 2010, Volume 102, Issue 6, pp. 640 - 648
Journal Article