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Peptides, ISSN 0196-9781, 2007, Volume 28, Issue 9, pp. 1631 - 1639
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 04/2011, Volume 17, Issue 10, pp. 1002 - 1024
In neurological insults, such as cerebral ischemia and traumatic brain injury, complex molecular mechanisms involving inflammation and apoptosis are known to... 
G protein-coupled receptor | Neuroprotection | Stroke | Bioactive conformation | Traumatic brain injury | PACAP | Peptide drug design | VIP | CYCLASE-ACTIVATING POLYPEPTIDE | VASOACTIVE-INTESTINAL-PEPTIDE | BLOOD-BRAIN-BARRIER | CEREBELLAR GRANULE CELLS | HUMAN-SERUM-ALBUMIN | GLUCAGON-LIKE PEPTIDE-1 | PROTEIN-COUPLED RECEPTOR | N-TERMINAL ECTODOMAIN | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | DIABETIC DB/DB MICE | Neuroprotective Agents - therapeutic use | Receptors, G-Protein-Coupled - metabolism | Apoptosis - drug effects | Brain Injuries - drug therapy | Humans | Astrocytes - pathology | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Drug Discovery - methods | Nerve Growth Factors - metabolism | Brain Ischemia - immunology | Brain Injuries - immunology | Neuroprotective Agents - adverse effects | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - physiology | Cytokines - immunology | Astrocytes - drug effects | Cell Survival - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - adverse effects | Pituitary Adenylate Cyclase-Activating Polypeptide - physiology | Animals | Pituitary Adenylate Cyclase-Activating Polypeptide - therapeutic use | Brain Ischemia - drug therapy | Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Brain Ischemia - pathology | Brain Injuries - pathology | Astrocytes - metabolism | Drugs | Cytokines | Astrocytes | Macromolecules | Inflammation | Drug development | Neuroprotective agents | Blood | Microglia | Pituitary adenylate cyclase-activating polypeptide | Chemical modification | Neurotransmitters | Side effects | Molecular modelling | Ischemia | Pharmacokinetics | Apoptosis
Journal Article
Angewandte Chemie, ISSN 1433-7851, 09/2015, Volume 54, Issue 38, p. 11128
  Reported is the ability of [alpha]-helical polypeptides to self-assemble with oppositely-charged polypeptides to form liquid complexes while maintaining... 
Polypeptides
Journal Article
Soft Matter, ISSN 1744-683X, 12/2014, Volume 11, Issue 2, pp. 422 - 422
Correction for 'Phase behaviour and complex coacervation of aqueous polypeptide solutions' by Dimitrios Priftis et al. , Soft Matter , 2012, 8 , 9396-9405. 
Polypeptides
Journal Article
Journal Article
2006, Annals of the New York Academy of Sciences, ISBN 9781573315500, Volume 1070, xxi, 633
Book
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2009, Volume 121, Issue 3, pp. 294 - 316
Vasoactive intestinal peptide (VIP) and the pituitary adenylate cyclase activating polypeptides (PACAPs) share 68% identity at the amino acid level and belong... 
Receptor variants | G-protein coupled receptor | PACAP | VIP | PACR | VPACR | CYCLASE-ACTIVATING POLYPEPTIDE | HUMAN NEUROBLASTOMA-CELLS | VASOACTIVE-INTESTINAL-PEPTIDE | WATERY-DIARRHEA SYNDROME | DIFFERENTIAL SIGNAL-TRANSDUCTION | GILA MONSTER VENOM | STIMULATES ADENYLATE-CYCLASE | PROTEIN-COUPLED-RECEPTORS | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | PHOSPHOLIPASE-C ACTIVATION | Amino Acid Sequence | Signal Transduction | Receptors, Vasoactive Intestinal Peptide, Type II - agonists | Receptors, Vasoactive Intestinal Polypeptide, Type I - physiology | Mice, Transgenic | Pituitary Adenylate Cyclase-Activating Polypeptide - physiology | Organ Specificity | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - physiology | Phospholipase D - metabolism | Receptors, Vasoactive Intestinal Peptide, Type II - genetics | Receptors, Vasoactive Intestinal Polypeptide, Type I - genetics | Receptors, Vasoactive Intestinal Peptide, Type II - physiology | Animals | Vasoactive Intestinal Peptide - physiology | Receptors, Vasoactive Intestinal Polypeptide, Type I - agonists | Base Sequence | Ligands | Mice | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - agonists | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Cyclic AMP - metabolism | Hypertension | Coenzymes | Inositol | Somatotropin releasing hormone | Peptides | Guanosine | Leukemia | Inositol phosphates | Amino acids | Lipids | Cyclic adenylic acid | Hormones | Muscle proteins | Embryonic stem cells | Hamsters | Adenylate cyclase | Synthesis | Analysis | Physiological aspects | Phospholipases | Nuclear magnetic resonance | Adenylic acid | Concentration camps | Adenosine triphosphate
Journal Article
Cephalalgia, ISSN 0333-1024, 1/2011, Volume 31, Issue 2, pp. 181 - 189
Objective: We pharmacologically characterized pituitary adenylate cyclase–activating polypeptides (PACAPs), vasoactive intestinal peptide (VIP) and the VPAC1,... 
PAC1 | PACAP38 | VPAC1 | VIP | VPAC2 | CYCLASE-ACTIVATING POLYPEPTIDE | RAT | IMMUNOHISTOCHEMICAL LOCALIZATION | MIGRAINE | NEUROSCIENCES | PEPTIDE | CLINICAL NEUROLOGY | PAC | VPAC | MESSENGER-RNA | HEADACHE | CEREBRAL-ARTERIES | HEALTHY-VOLUNTEERS | EXPRESSION | Pituitary Adenylate Cyclase-Activating Polypeptide - antagonists & inhibitors | Receptors, Vasoactive Intestinal Polypeptide, Type I - antagonists & inhibitors | Gene Expression - drug effects | Receptors, Vasoactive Intestinal Peptide, Type II - agonists | Humans | Middle Aged | Male | Peptide Fragments - pharmacology | Receptors, Vasoactive Intestinal Peptide - genetics | RNA, Messenger - metabolism | Receptors, Vasoactive Intestinal Peptide, Type II - genetics | Meningeal Arteries - physiology | Vasoactive Intestinal Peptide - pharmacology | Receptors, Vasoactive Intestinal Polypeptide, Type I - agonists | Gene Expression - physiology | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Migraine Disorders - physiopathology | Adult | Female | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - agonists | Vasodilation - physiology | Coronary Vessels - drug effects | Receptors, Vasoactive Intestinal Peptide, Type II - antagonists & inhibitors | Vasodilator Agents - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Coronary Vessels - physiology | Pituitary Adenylate Cyclase-Activating Polypeptide - adverse effects | Meningeal Arteries - drug effects | Migraine Disorders - drug therapy | Receptors, Vasoactive Intestinal Polypeptide, Type I - genetics | Aged | Receptors, Vasoactive Intestinal Peptide - antagonists & inhibitors | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Vasodilation - drug effects | Receptors, Vasoactive Intestinal Peptide - agonists | Vasoactive Intestinal Peptide - analogs & derivatives | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - antagonists & inhibitors
Journal Article
Peptides, ISSN 0196-9781, 2008, Volume 29, Issue 6, pp. 919 - 932
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38- or 27-amino acid neuropeptide with promising therapeutic applications for the treatment of... 
Plasma metabolites | Stable analogs | PAC1 receptor agonists | Dipeptidyl peptidase IV | PACAP | CEREBELLAR GRANULE NEURONS | CYCLASE-ACTIVATING POLYPEPTIDE | VASOACTIVE-INTESTINAL-PEPTIDE | stable analogs | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | ENDOGENOUS PACAP | plasma metabolites | GLUCAGON-LIKE PEPTIDE-1 | STRUCTURAL REQUIREMENTS | IN-VIVO | PC-12 CELLS | dipeptidyl peptidase IV | PHARMACOLOGY & PHARMACY | ADENYLATE-CYCLASE | Cricetulus | Humans | Pituitary Adenylate Cyclase-Activating Polypeptide - chemical synthesis | Molecular Sequence Data | PC12 Cells | Dose-Response Relationship, Drug | Pituitary Adenylate Cyclase-Activating Polypeptide - isolation & purification | Protein Isoforms - metabolism | Time Factors | Protein Isoforms - chemistry | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - blood | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | CHO Cells | Amino Acid Sequence | Cricetinae | Cell Size - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - chemistry | Rats | Electroporation | Animals | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - drug effects | Cell Differentiation - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Protein Binding | Cell Proliferation - drug effects | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | DNA, Complementary | Protein Isoforms - genetics
Journal Article
British Journal of Dermatology, ISSN 0007-0963, 02/2017, Volume 176, Issue 2, pp. 413 - 422
What's already known about this topic? Pituitary adenylate cyclase‐activating polypeptide (PACAP) exhibits pleiotropic functions in the central nervous system,... 
FOCAL HYPERHIDROSIS | CELLS | PACAP | MOUSE MODEL | THORACOSCOPIC SYMPATHECTOMY | CYSTIC-FIBROSIS | VIP | SKIN IN-VIVO | EXPRESSION | AQUAPORIN-5 | DERMATOLOGY | Nerve Fibers - metabolism | Eccrine Glands - secretion | Sweat - secretion | Humans | Mice, Inbred C57BL | Receptors, Vasoactive Intestinal Peptide, Type II - metabolism | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - physiology | Male | Pituitary Adenylate Cyclase-Activating Polypeptide - physiology | RNA, Messenger - metabolism | Foot | Receptors, Vasoactive Intestinal Peptide, Type II - physiology | Animals | Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Adult | Female | Receptors, Vasoactive Intestinal Polypeptide, Type I - metabolism | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - physiology | Vasoactive intestinal peptides | Skin diseases | Skin | Neuroprotection | Sjogren's syndrome | RNA-directed DNA polymerase | Adrenal glands | Glands | Central nervous system | Lichen planus | Dermatitis | Vasodilation | Intestine | Atopic dermatitis | Vasoactive agents | Rodents | Localization | Sweat | Iodine | Sweating | Polypeptides | Psoriasis | Starch | Secretion | Fabry's disease | Exocrine glands | Polymerase chain reaction | Pituitary adenylate cyclase-activating polypeptide | Molecular modelling | Immunoreactivity | Neurotransmission | Index Medicus
Journal Article
Diabetologia, ISSN 0012-186X, 04/2000, Volume 43, Issue 4, pp. 393 - 410
The pancreatic islets are richly innervated by parasympathetic, sympathetic and sensory nerves. Several different neurotransmitters are stored within the... 
Islets, parasympathetic, sympathetic, acetylcholine, vasoactive intestinal polypeptide, pituitary adenylate cyclase activating polypeptide, gastrin releasing peptide, noradrenaline, galanin, neuropeptide Y, calcitonin gene-related polypeptide, cholecystokinin, insulin secretion, glucagon secretion, cephalic phase, oscillation, hypoglycaemia, impaired glucose tolerance, diabetes | Neuropeptide Y | Parasympathetic | Galanin | Hypoglycaemia | Calcitonin gene- related polypeptide | Sympathetic | Insulin secretion | Pituitary adenylate cyclase activating polypeptide | Gastrin releasing peptide | Cephalic phase | Vasoactive intestinal polypeptide | Oscillation | Acetylcholine | Glucagon secretion | Islets | Cholecystokinin | Diabetes | Impaired glucose tolerance | Noradrenaline | CYCLASE-ACTIVATING POLYPEPTIDE | ISOLATED RAT ISLETS | GENE-RELATED PEPTIDE | sympathetic | neuropeptide Y | cholecystokinin | impaired glucose tolerance | CAPSAICIN-SENSITIVE NERVES | calcitonin gene-related polypeptide | islets | ENDOCRINOLOGY & METABOLISM | oscillation | noradrenaline | CEPHALIC-PHASE INSULIN | gastrin releasing peptide | cephalic phase | polypeptide | galanin | hypoglycaemia | GASTRIN-RELEASING PEPTIDE | insulin secretion | pituitary adenylate cyclase activating | parasympathetic | MUSCARINIC RECEPTOR SUBTYPES | glucagon secretion | PANCREATIC BETA-CELLS | SYMPATHETIC-NERVE STIMULATION | acetylcholine | diabetes | vasoactive intestinal polypeptide | Humans | Insulin Resistance | Homeostasis | Islets of Langerhans - innervation | Obesity - physiopathology | Sympathetic Nervous System - physiopathology | Autonomic Nervous System - physiopathology | Insulin - metabolism | Diabetes Mellitus - physiopathology | Islets of Langerhans - metabolism | Parasympathetic Nervous System - physiopathology | Insulin Secretion | Neurotransmitter Agents - physiology | Glucose metabolism | Neurotransmitters | Gastrin | Neuropeptides | Glucose | Dextrose
Journal Article