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Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 11/2012, Volume 48, Issue 3, pp. 482 - 492
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a widespread neuropeptide with a diverse array of biological functions. Not surprisingly, the... 
Neurochemistry | Neurology | Neurosciences | Biomedicine | Ischemia | Proteomics | Protection | Knockout | Cell Biology | Cytoprotective | CYCLASE-ACTIVATING POLYPEPTIDE | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURONAL CELL-DEATH | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | IN-VITRO | INCREASED SENSITIVITY | ADENYLATE-CYCLASE | NEUROPEPTIDE PACAP | CEREBRAL-ISCHEMIA | EXPRESSION | Kidney Diseases - physiopathology | Stress, Physiological - physiology | Autoimmune Diseases - physiopathology | Disease Susceptibility | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Neurotoxins - toxicity | Ischemia - physiopathology | Noxae - adverse effects | Pituitary Adenylate Cyclase-Activating Polypeptide - physiology | Wounds and Injuries - physiopathology | Mice, Knockout | Cardiomyopathies - physiopathology | Animals | Homeostasis - physiology | Lung Diseases - physiopathology | Mice | Nervous System Diseases - physiopathology | Dermatitis, Allergic Contact - physiopathology | Pancreatic Diseases - physiopathology | Inflammation - physiopathology | Pituitary Adenylate Cyclase-Activating Polypeptide - deficiency | Index Medicus | Cell culture | Oxidative stress | Cytokines | Encephalomyelitis | Cardiomyopathy | Data processing | Nervous system | Inflammation | Small intestine | Kidney | Pituitary adenylate cyclase-activating polypeptide | Reperfusion | Reviews | Contact dermatitis | Excitotoxicity | Respiratory tract diseases | Pancreas | Injuries
Journal Article
Peptides, ISSN 0196-9781, 04/2015, Volume 66, pp. 26 - 42
Journal Article
2006, Annals of the New York Academy of Sciences, ISBN 9781573315500, Volume 1070, xxi, 633
Book
Journal of Comparative Neurology, ISSN 0021-9967, 12/2016, Volume 524, Issue 18, pp. 3827 - 3848
Pituitary adenylate cyclase‐activating polypeptide (PACAP, gene name Adcyap1 ) regulates a wide variety of neurological and physiological functions, including... 
RRID:AB_2336201 | RRID:SciRes_000137 | RRID:AB_10058149 | neuropeptide | RRID:AB_10680176 | RRID:nlx_143660 | RRID:AB_177621 | facial nerve axotomy | Adcyap1 | central nervous system | pituitary adenylyl cyclase‐activating polypeptide | RRID:IMSR_MMRRC:012011 | RRID:AB_10073917 | RRID:AB_10049744 | reporter mouse | RRID:AB_10563748 | Central nervous system | Reporter mouse | Neuropeptide | Pituitary adenylyl cyclase-activating polypeptide | Facial nerve axotomy | pituitary adenylyl cyclase-activating polypeptide | CYCLASE-ACTIVATING POLYPEPTIDE | DORSAL-ROOT GANGLIA | HYPOTHALAMIC PARAVENTRICULAR NUCLEUS | ZOOLOGY | MESSENGER-RNA | CENTRAL-NERVOUS-SYSTEM | RETINOHYPOTHALAMIC TRACT | NEUROSCIENCES | PEPTIDE GENE-EXPRESSION | VASOACTIVE INTESTINAL POLYPEPTIDE | RAT-BRAIN | ADENYLATE-CYCLASE | Immunohistochemistry | Green Fluorescent Proteins - metabolism | Brain - cytology | Spinal Cord - metabolism | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Male | Mice, Transgenic | Facial Nerve Injuries - metabolism | Gene Expression Profiling | Green Fluorescent Proteins - genetics | Brain - metabolism | Axotomy | Animals | Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Facial Nerve Injuries - pathology | Models, Animal | Neurons - metabolism | Spinal Cord - cytology | Genetic engineering | Colchicine | Peptides | Neurons | Genetic translation | Analysis | Index Medicus
Journal Article
10/2016, Current Topics in Neurotoxicity, ISBN 3319351338, Volume 11, 818
eBook
Nature, ISSN 0028-0836, 02/2011, Volume 470, Issue 7335, pp. 492 - 497
Pituitary adenylate cyclase-activating polypeptide (PACAP) is known to broadly regulate the cellular stress response. In contrast, it is unclear if the... 
SIGNAL-TRANSDUCTION | PTSD | CYCLASE-ACTIVATING POLYPEPTIDE | STRIA TERMINALIS | MULTIDISCIPLINARY SCIENCES | BRAIN-DEVELOPMENT | GENE-EXPRESSION | FEAR INHIBITION | ADENYLATE-CYCLASE | BED NUCLEUS | AMYGDALA | Septal Nuclei - drug effects | Estrogens - pharmacology | Humans | RNA, Messenger - analysis | Male | Stress Disorders, Post-Traumatic - physiopathology | Fear - physiology | RNA, Messenger - biosynthesis | Septal Nuclei - metabolism | DNA Methylation | Pituitary Adenylate Cyclase-Activating Polypeptide - blood | Female | Response Elements - genetics | Estrogens - metabolism | Genetic Predisposition to Disease - genetics | Genetic Association Studies | Pituitary Adenylate Cyclase-Activating Polypeptide - chemistry | RNA, Messenger - genetics | Amygdala - metabolism | Rats | Stress Disorders, Post-Traumatic - psychology | Sex Characteristics | Conditioning, Classical - physiology | Gene Expression Regulation - drug effects | Stress Disorders, Post-Traumatic - blood | Animals | CpG Islands - genetics | Polymorphism, Single Nucleotide - genetics | Mice | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Stress Disorders, Post-Traumatic - genetics | Psychological aspects | Physiological aspects | Causes of | Genetic aspects | Polypeptides | Post-traumatic stress disorder | Studies | Gene expression | Females | Males | Rodents | Index Medicus | Depressive Disorders | Neuroendocrinology | Neurobiology | Survivors | Americans | Neuroendocrine Testing | Genetic Markers | Psychiatric Disorders | Reexperiencing | PTSD (DSM-IV) | Startle Reflex | Neurophysiology | Predisposition | Arousal | Adults | Stressors | Avoidance | Biologic Markers
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2018, Volume 314, Issue 3, pp. H563 - H572
Intermittent hypoxia causes a persistent increase in sympathetic activity that progresses to hypertension in chronic conditions such as obstructive sleep... 
Pituitary adenylate cyclase-activating polypeptide | Sympathetic activity | Cardiovascular | Obstructive sleep apnea | Rostral ventrolateral medulla | obstructive sleep apnea | CYCLASE-ACTIVATING POLYPEPTIDE | rostral ventrolateral medulla | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | pituitary adenylate cyclase-activating polypeptide | BARORECEPTOR REFLEX | VASOMOTOR NEURONS | sympathetic activity | BRAIN-STEM | cardiovascular | NERVE ACTIVITY | AMPA/KAINATE RECEPTORS | INCREASES BAROSENSITIVITY | RESPIRATORY DRIVE | PERIPHERAL VASCULAR DISEASE | RAT IN-VIVO | Receptors, Glutamate - metabolism | Sleep Apnea, Obstructive - physiopathology | Sympathetic Nervous System - drug effects | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Male | Sleep Apnea, Obstructive - complications | gamma-Aminobutyric Acid - administration & dosage | Sympathetic Nervous System - physiopathology | Receptors, Glutamate - drug effects | Sympathetic Nervous System - metabolism | Hypertension - etiology | Hypoxia - metabolism | Medulla Oblongata - physiopathology | Long-Term Potentiation - drug effects | Time Factors | Synaptic Transmission - drug effects | Disease Models, Animal | Acute Disease | Microinjections | Medulla Oblongata - drug effects | Peptide Fragments - administration & dosage | Medulla Oblongata - metabolism | Hypoxia - complications | Rats, Sprague-Dawley | Hypertension - physiopathology | Sleep Apnea, Obstructive - metabolism | Glutamic Acid - administration & dosage | Animals | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - drug effects | Hypoxia - physiopathology | Pituitary Adenylate Cyclase-Activating Polypeptide - administration & dosage | Kynurenic Acid - administration & dosage | Prevention | Physiological aspects | Hypoxia | Polypeptides | Apnea | Health aspects | Hypertension | Amino acids | Sleep apnea | Activation | Urethane | Metabolism | Sleep disorders | Receptors | γ-Aminobutyric acid | Chronic conditions | Sleep | Microinjection | Intestine | Vasoactive agents | Rodents | Vasoactive intestinal peptide | Pituitary adenylate cyclase-activating polypeptide receptors | Ventilation | Medulla oblongata | Pretreatment | Index Medicus
Journal Article
Psychoneuroendocrinology, ISSN 0306-4530, 2008, Volume 34, Issue 6, pp. 833 - 843
Summary Exposure to chronic stress has been argued to produce maladaptive anxiety-like behavioral states, and many of the brain regions associated with... 
Endocrinology & Metabolism | Psychiatry | Fear | PAC 1 receptor | Corticotropin-releasing hormone | Extended amygdala | Plasticity | Vasoactive intestinal peptide | PAC | receptor | PAC receptor | RAT | PSYCHIATRY | IN-SITU HYBRIDIZATION | SYMPATHETIC NEURONS | NEUROSCIENCES | HYPOTHALAMIC PARAVENTRICULAR NUCLEUS | RECEPTOR-DEFICIENT MICE | NEURITE OUTGROWTH | ENDOCRINOLOGY & METABOLISM | POLYPEPTIDE PACAP | GENE-EXPRESSION | AMYGDALA | Brain-Derived Neurotrophic Factor - genetics | Septal Nuclei - drug effects | Neuronal Plasticity - drug effects | Male | Receptor, trkB - genetics | RNA, Messenger - metabolism | Septal Nuclei - metabolism | Neuronal Plasticity - genetics | Time Factors | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Stress, Psychological - metabolism | Behavior, Animal - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Anxiety - metabolism | Stress, Psychological - chemically induced | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Adaptation, Psychological - drug effects | Rats | Behavior, Animal - physiology | Up-Regulation - genetics | Pituitary Adenylate Cyclase-Activating Polypeptide - physiology | Rats, Sprague-Dawley | Up-Regulation - drug effects | Stress, Psychological - genetics | Anxiety - genetics | Animals | Models, Biological | Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Anxiety - chemically induced | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Chronic Disease | Receptor, trkB - metabolism | Anxiety - etiology | Tyrosine | Adenylate cyclase | Messenger RNA | Polypeptides | ACTH | Hormones | Growth factors | Index Medicus | corticotropin-releasing hormone | PAC1 receptor
Journal Article
Brain Research, ISSN 0006-8993, 2015, Volume 1600, Issue Nov 20, pp. 93 - 109
Abstract Calcitonin gene-related peptide (CGRP) receptor antagonists have demonstrated anti-migraine efficacy. One remaining question is where do these... 
Neurology | CLR | Evans blue | CGRP receptor antagonists | Trigeminal ganglion | RAMP1 | CGRP | TRIGEMINOVASCULAR SYSTEM | NERVE-FIBERS | GENE-RELATED PEPTIDE | NITRIC-OXIDE SYNTHASE | MIGRAINE-LIKE ATTACKS | VASCULAR-PERMEABILITY | NEUROSCIENCES | FtAMP1 | CEREBRAL-ARTERY | EXTRACEREBRAL CIRCULATION | SUBSTANCE-P | ACTIVITY-MODIFYING PROTEIN-1 | Calcitonin Gene-Related Peptide - analysis | Receptors, Calcitonin Gene-Related Peptide - antagonists & inhibitors | Rats | Trigeminal Ganglion - metabolism | Male | Macaca mulatta | Receptor Activity-Modifying Protein 1 - analysis | Trigeminal Ganglion - diagnostic imaging | Rats, Sprague-Dawley | Receptors, Calcitonin Gene-Related Peptide - metabolism | Blood-Brain Barrier - metabolism | Calcitonin Receptor-Like Protein - analysis | Pituitary Adenylate Cyclase-Activating Polypeptide - analysis | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Receptors, Calcitonin Gene-Related Peptide - analysis | Animals | Radionuclide Imaging | Female | Neurons - metabolism | Spiro Compounds - pharmacology | Glutamic Acid - analysis | Amino acids | Peptides | Glutamate | Ganglion | Lubrication and lubricants | Migraine | Index Medicus | Basic Medicine | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
Journal Article