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NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 10/2018, Volume 379, Issue 17, pp. 1621 - 1634
BACKGROUND A vaccine to interrupt the transmission of tuberculosis is needed. METHODS We conducted a randomized, double-blind, placebo-controlled, phase 2b... 
MYCOBACTERIUM-TUBERCULOSIS | SOUTH-AFRICA | MEDICINE, GENERAL & INTERNAL | IMMUNOGENICITY | T-CELL RESPONSES | MTB72F POLYPROTEIN | IMMUNE-RESPONSES | RANDOMIZED-TRIAL | BCG REVACCINATION | HIV-INFECTED ADULTS | POLYPROTEIN VACCINE
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2016, Volume 60, Issue 12, pp. 7382 - 7395
Chikungunya virus (CHIKV; genus Alphavirus) is the causative agent of chikungunya fever. CHIKV replication can be inhibited by some broad-spectrum antiviral... 
NSP2 PROTEASE | SINDBIS VIRUS | RNA-SYNTHESIS | REPLICATION | EQUINE ENCEPHALITIS-VIRUS | VIRAL MACRO DOMAINS | RESONANCE ENERGY-TRANSFER | ANTIVIRAL ACTIVITY | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | NONSTRUCTURAL PROTEIN-2 | POLYPROTEIN CLEAVAGE | Cysteine Endopeptidases - chemistry | RNA Helicases - metabolism | Chikungunya virus - genetics | Polyproteins - metabolism | Stereoisomerism | Carboxylic Acids - chemical synthesis | Epithelial Cells - drug effects | Crystallography, X-Ray | Structure-Activity Relationship | RNA Helicases - chemistry | Protease Inhibitors - pharmacology | Cyclopropanes - chemical synthesis | Cysteine Endopeptidases - metabolism | Drug Design | Polyproteins - antagonists & inhibitors | Inhibitory Concentration 50 | RNA Helicases - genetics | Carboxylic Acids - pharmacology | Cyclopropanes - pharmacology | Cell Line | Genome, Viral | Virus Replication - drug effects | Catalytic Domain | Chikungunya virus - enzymology | Cricetinae | Polyproteins - chemistry | Polyproteins - genetics | Chikungunya virus - growth & development | RNA Helicases - antagonists & inhibitors | Chikungunya virus - drug effects | Animals | Cysteine Endopeptidases - genetics | Epithelial Cells - virology | Antiviral Agents - chemical synthesis | Molecular Docking Simulation | Protease Inhibitors - chemical synthesis
Journal Article
REVIEW ARTICLE - Plant virus gene expression strategies, 08/1998
Plant viruses can cause serious losses to most, if not all, major crops upon which depend for food. Many viruses are endemic, causing moderate losses each... 
Plant virus, Gene expression, Subgenomic RNA, Frameshifting, Read-through, Polyprotein ej98010 | Biotechnology
Journal
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 41, pp. 16534 - 16539
Journal Article
Science, ISSN 0036-8075, 4/2009, Volume 324, Issue 5923, pp. 55 - 59
Journal Article
Annual Review of Biochemistry, ISSN 0066-4154, 6/2017, Volume 86, Issue 1, pp. 609 - 636
Lipids are produced site-specifically in cells and then distributed nonrandomly among membranes via vesicular and nonvesicular trafficking mechanisms. The... 
GLTP-fold | protein helical layering bundling | nonspecific lipid transfer proteins | nuclear receptor ligand-binding domains | sphingolipid transfer proteins | fixed versus expandable hydrophobic pockets | saposins | lipid headgroup recognition centers | albumins | nematode polyprotein allergens antigens | Fixed versus expandable hydrophobic pockets | Sphingolipid transfer proteins | Albumins | Nuclear receptor ligand-binding domains | Lipid headgroup recognition centers | Saposins | Protein helical layeringbundling | Nonspecific lipid transfer proteins | Nematode polyprotein allergensantigens | protein helical layering/bundling | HUMAN SAPOSIN-C | LIGAND-BINDING | HUMAN SERUM-ALBUMIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR RECEPTOR SUPERFAMILY | MEMBRANE INTERACTION | FATTY-ACIDS | NONVESICULAR TRAFFICKING | nematode polyprotein allergens/antigens | STRUCTURAL BASIS | GLYCOLIPID TRANSFER PROTEIN | Albumins - chemistry | Protein Conformation, alpha-Helical | Gene Expression | Albumins - metabolism | Humans | Models, Molecular | Lipid Metabolism | Allergens - genetics | Antigens - metabolism | Antigens - chemistry | Allergens - metabolism | Carrier Proteins - genetics | Lipids - chemistry | Animals | Carrier Proteins - metabolism | Biological Transport | Protein Conformation, beta-Strand | Allergens - chemistry | Protein Binding | Protein Domains | Carrier Proteins - chemistry | Albumins - genetics | Binding Sites | Antigens - genetics | Physiological aspects | Lipids | Genetic aspects | Protein binding
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2019, Volume 508, Issue 3, pp. 791 - 796
Recent developments in tumour treatment had focused on virotherapies that were currently revolutionising new innovated treatment pathways. This study focused... 
Oncolytic adenoviral nanosphere | Polyprotein surface precipitation technique | Polyprotein | Self-targeted | Virotherapy | CELLS | GENE DELIVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELEASE | NANOPARTICLES | BIOPHYSICS | BIOLOGICAL EVALUATION | LAYER | DERIVATIVES | LIPOSOMES
Journal Article