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American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 08/2018, Volume 315, Issue 2, pp. F199 - F210
The molecular mechanisms of melamine-induced renal toxicity have not been fully understood. The purpose of the study aimed to investigate whether melamine and... 
Cyanuric acid | Inflammasome | AQP2 | Melamine | SPRAGUE-DAWLEY RATS | CATS | PHYSIOLOGY | TRANSPORTERS | INTERLEUKIN-1-BETA | melamine | UNILATERAL URETERAL OBSTRUCTION | inflammasome | cyanuric acid | RENAL TOXICITY | UROLOGY & NEPHROLOGY | SECRETION | ALTERED EXPRESSION | KIDNEY | NF-KAPPA-B | Triazines | Phosphorylation | Inflammasomes - metabolism | Kidney - pathology | Rats, Wistar | Caspase 1 - metabolism | Male | NF-kappa B - metabolism | Sodium-Potassium-Chloride Symporters - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | CARD Signaling Adaptor Proteins - metabolism | Kidney - metabolism | Interleukin-1beta - metabolism | Kidney Concentrating Ability | Polyuria - pathology | Antigens, Differentiation - metabolism | Kidney - physiopathology | Signal Transduction | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Aquaporins - metabolism | Polyuria - metabolism | CD3 Complex - metabolism | Antigens, Differentiation, Myelomonocytic - genetics | Polyuria - chemically induced | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Antigens, Differentiation - genetics | Polyuria - physiopathology | Physiological aspects | Urination disorders | Health aspects | Toxicity | Renal tubules | Caspase-1 | Aquaporin 2 | Urine | NF-κB protein | Kidneys | Cytokines | Crystals | Caspase | CD3 antigen | Inflammation | Na+/K+-exchanging ATPase | Gene expression | Organelles | Cell suspensions | Molecular modelling | Pyrin protein | Sodium | Speck | Collecting duct | Polyuria | Apoptosis | Index Medicus
Journal Article
02/2010
Objective: Nocturnal enuresis is a common diagnosis in patients referred to pediatric and pediatric nephrology clinics. Nocturnal polyuria is an important... 
Desmopressin | Hypercalciuria | Enuresis | Polyuria | Bedwetting
Web Resource
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 8, pp. 3030 - 3034
The present study demonstrates a key role for the oxysterol receptor liver X receptor β (LXRβ) in the etiology of diabetes insipidus (Dl). Given free access to... 
Urine | Receptors | Excretion | Kidneys | Neurons | Liver | Metabolism cages | Mice | Polyuria | Dehydration | Hormones | Pituitary | Cholesterol | Oxysterols | pituitary | CELLS | oxysterols | hormones | MULTIDISCIPLINARY SCIENCES | WATER CHANNELS | OXYSTEROL | ALPHA | MODEL | LXR-BETA | HORMONE | GENE | NEURONS | cholesterol | Polydipsia - blood | Kidney - pathology | Dehydration - complications | Supraoptic Nucleus - metabolism | Dehydration - urine | Orphan Nuclear Receptors - metabolism | Aquaporin 1 - metabolism | Benzylamines - administration & dosage | Paraventricular Hypothalamic Nucleus - physiopathology | Supraoptic Nucleus - drug effects | Kidney - metabolism | Osmolar Concentration | Diabetes Insipidus, Neurogenic - physiopathology | Liver X Receptors | Polyuria - blood | Polyuria - complications | Arginine Vasopressin - administration & dosage | Arginine Vasopressin - urine | Diabetes Insipidus, Neurogenic - complications | Female | Dehydration - physiopathology | Neurons - metabolism | Neurons - drug effects | Polyuria - urine | Kidney - physiopathology | Polydipsia - physiopathology | Polydipsia - urine | Water-Electrolyte Balance - physiology | Dehydration - blood | Diabetes Insipidus, Neurogenic - pathology | Diabetes Insipidus, Neurogenic - metabolism | Supraoptic Nucleus - pathology | Arginine Vasopressin - pharmacology | Body Water | Benzoates - administration & dosage | Supraoptic Nucleus - physiopathology | Orphan Nuclear Receptors - deficiency | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Paraventricular Hypothalamic Nucleus - metabolism | Benzoates - pharmacology | Benzylamines - pharmacology | Polydipsia - complications | Paraventricular Hypothalamic Nucleus - pathology | Polyuria - physiopathology | Index Medicus | Biological Sciences
Journal Article
Kidney International, ISSN 0085-2538, 04/2017, Volume 91, Issue 4, pp. 842 - 855
Dent disease is a rare X-linked tubulopathy caused by mutations in the endosomal chloride-proton exchanger (ClC-5) resulting in defective receptor-mediated... 
ClC-5 | low-molecular weight proteinuria | renal Fanconi syndrome | bone marrow cell | proximal tubule | TRAFFICKING | CUBILIN | MESENCHYMAL STEM-CELLS | CLC-5 | CIC-5 | TUNNELING NANOTUBES | IMPAIRS ENDOCYTOSIS | CYSTINOSIS | UROLOGY & NEPHROLOGY | MEGALIN | CHLORIDE CHANNEL | KIDNEY | Polyuria - genetics | Coculture Techniques | Male | Chloride Channels - deficiency | Chloride Channels - genetics | Recovery of Function | Proteinuria - prevention & control | Dent Disease - physiopathology | Endocytosis | Glycosuria - prevention & control | Dent Disease - genetics | Hypercalciuria - prevention & control | Bone Marrow Transplantation | Dent Disease - metabolism | Hypercalciuria - genetics | Disease Models, Animal | Glycosuria - physiopathology | Kidney Tubules, Proximal - physiopathology | Polyuria - prevention & control | Genetic Predisposition to Disease | Kidney Tubules, Proximal - pathology | Glycosuria - genetics | Hypercalciuria - physiopathology | Mice, Inbred C57BL | Cells, Cultured | Cell Communication | Proteinuria - metabolism | Low Density Lipoprotein Receptor-Related Protein-2 - metabolism | Polyuria - metabolism | Proteinuria - genetics | Transplantation Chimera | Glycosuria - metabolism | Mice, Knockout | Proteinuria - physiopathology | Phenotype | Animals | Dent Disease - surgery | Hypercalciuria - metabolism | Kidney Tubules, Proximal - metabolism | Polyuria - physiopathology | Index Medicus
Journal Article
Archives de pédiatrie, ISSN 0929-693X, 01/2018, Volume 25, Issue 1, pp. 45 - 47
Diabetes insipidus is characterized by hypoosmotic polyuria related to deficiency of arginine–vasopressin (AVP) secretion (central diabetes insipidus, CDI) or... 
Children | Polyuria–polydipsia syndrome | Diabetes insipidus | Vasopressin | Copeptin | Polyuria-polydipsia syndrome | Diabetes Insipidus - blood | Diagnosis, Differential | Humans | Diabetes Insipidus - diagnosis | Glycopeptides - blood | Infant | Male | Polyuria - etiology | Biomarkers - blood | Polydipsia - diagnosis | Polyuria - diagnosis | Polydipsia - etiology | Index Medicus
Journal Article
Journal Article
American Journal of Physiology : Renal Physiology, ISSN 1931-857X, 2017, Volume 313, Issue 3, pp. F669 - f676
Lithium is the mainstay treatment for patients with bipolar disorder, but it generally causes nephrogenic diabetes insipidus (NDI), a disorder in which the... 
Acetazolamide | Lithium | GFR | NDI | Mice | Patients | SODIUM | PHYSIOLOGY | PRINCIPAL CELLS | patients | ANTIDIURETIC-HORMONE | mice | HYPERTONIC URINE | HYDROCHLOROTHIAZIDE | lithium | COLLECTING DUCT | acetazolamide | UROLOGY & NEPHROLOGY | AQUAPORIN-2 | NEPHROGENIC DIABETES-INSIPIDUS | INHIBITOR | EXPRESSION | Prospective Studies | Diabetes Insipidus, Nephrogenic - physiopathology | Humans | Middle Aged | Polyuria - drug therapy | Male | Kidney Concentrating Ability - drug effects | Diabetes Insipidus, Nephrogenic - drug therapy | Glomerular Filtration Rate - drug effects | Kidney - metabolism | Netherlands | Osmolar Concentration | Time Factors | Female | Blood Pressure - drug effects | Kidney - physiopathology | Disease Models, Animal | Lithium Chloride | Kidney - drug effects | Mice, Inbred C57BL | Treatment Outcome | Polyuria - chemically induced | Aquaporin 2 - metabolism | New Zealand | Acetazolamide - adverse effects | Pilot Projects | Animals | Diuretics - therapeutic use | Aged | Acetazolamide - therapeutic use | Diuretics - adverse effects | Diabetes Insipidus, Nephrogenic - chemically induced | Polyuria - physiopathology | Prevention | Complications and side effects | Diabetes insipidus | Patient outcomes | Causes of | Urination disorders | Dosage and administration | Drug therapy | Urine | Creatinine | Syngeneic grafts | Aquaporins | Water uptake | Bipolar disorder | Cells | Vasopressin | Glomerular filtration rate | Prescription drugs | Rodents | Blood pressure | Collecting duct | Polyuria | Aquaporin 2 | Kidney transplantation | Index Medicus
Journal Article
Journal Article