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ACS Chemical Neuroscience, ISSN 1948-7193, 07/2018, Volume 9, Issue 7, pp. 1818 - 1828
...” muscarinic acetylcholine (ACh) receptor (mAChR) positive allosteric modulators (PAMs). Using a combination of radioligand binding, functional inositol phosphate... 
operational model | cooperativity | efficacy | positive allosteric modulator | affinity | Muscarinic acetylcholine receptor
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 01/2018, Volume 61, Issue 1, pp. 251 - 264
We report here the synthesis of 7-phenoxy-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides and their evaluation as AMPA receptor positive allosteric modulators (AMPApams... 
SYSTEM | DESIGN | CHEMISTRY, MEDICINAL | MECHANISM | PHARMACOLOGY | X-RAY-SCATTERING | PROTEINS | BINDING | AMPA receptor | NMR | Synthesis | Positive allosteric modulators | Potency | Crystallography | SAXS
Journal Article
British journal of pharmacology, ISSN 0007-1188, 2013, Volume 168, Issue 8, pp. 2000 - 2010
Journal Article
Journal Article
Neuropharmacology, ISSN 0028-3908, 7/2018, Volume 137, pp. 50 - 58
.... In searching for the mechanism and potential intervention for opioid tolerance and dependence, we studied the action of two positive allosteric modulators of the α... 
AMPA | opioid tolerance | opioid dependence | positive allosteric modulator
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2015, Volume 25, Issue 6, pp. 1310 - 1317
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2015, Volume 172, Issue 18, pp. 4588 - 4590
...‐Urios I, Guilloteau V, Lluel P, Schneider M, Saporito M and Poli S (2014). ADX71441, a novel, potent and selective positive allosteric modulator of the GABAB... 
gastrointestinal | GABAB receptor | irritable bowel syndrome | colon | bladder pain syndrome | motility | positive allosteric modulator | visceral hypersensitivity | Commentaries
Journal Article
18.