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Diabetes, ISSN 0012-1797, 10/2016, Volume 65, Issue 10, pp. 3185 - 3199
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 11/2014, Volume 53, Issue 11, pp. 926 - 937
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2012, Volume 18, Issue 9, pp. 1350 - 1358
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2009, Volume 15, Issue 11, pp. 1266 - 1272
Macrophages rapidly engulf apoptotic cells to limit the release of noxious cellular contents and to restrict autoimmune responses against self antigens.... 
GLOMERULONEPHRITIS | AUTOANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | SYSTEMIC-LUPUS-ERYTHEMATOSUS | PHAGOCYTOSIS | PHOSPHATIDYLSERINE RECEPTOR | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACTIVATED RECEPTOR-DELTA | DEFICIENCY | BALB/C MICE | CELL BIOLOGY | INSULIN-RESISTANCE | Enzyme-Linked Immunosorbent Assay - methods | Autoimmune Diseases - physiopathology | Autoantibodies - metabolism | Apoptosis - drug effects | Humans | Mitochondrial Proteins | Promoter Regions, Genetic - drug effects | RNA, Messenger - metabolism | Autoimmune Diseases - genetics | Opsonin Proteins - genetics | Time Factors | Immune Tolerance - immunology | Hyaluronan Receptors - metabolism | Female | Autoimmune Diseases - pathology | Macrophages - immunology | PPAR delta - genetics | Disease Models, Animal | Immune Tolerance - drug effects | PPAR delta - deficiency | Phagocytosis - drug effects | Cytokines - metabolism | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Cells, Cultured | Phagocytosis - immunology | Thymus Gland - cytology | Opsonin Proteins - metabolism | Fluoresceins | Mice, Knockout | Gene Expression Regulation - drug effects | Autoimmunity - physiology | Autoantibodies - immunology | Macrophages - metabolism | Animals | Promoter Regions, Genetic - physiology | PPAR delta - agonists | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Thiazoles - pharmacology | Apoptosis - physiology | CD11b Antigen - metabolism | PPAR delta - metabolism | Autoimmunity - drug effects
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 06/2010, Volume 106, Issue 11, pp. 1712 - 1721
RATIONALE:Although dietary fatty acids are a major fuel for the heart, little is known about the direct effects of dietary fatty acids on gene regulation in... 
Peroxisome proliferator-activated receptor | Angptl4 | Cardiac oxidative stress | Gene expression | Fatty acids | CARDIAC & CARDIOVASCULAR SYSTEMS | fatty acids | MOUSE HEART | TRIGLYCERIDE-METABOLISM | ALPHA | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | cardiac oxidative stress | TARGET GENES | PLASMA | LIPOTOXIC CARDIOMYOPATHY | GENE-EXPRESSION | PPAR-GAMMA | PERIPHERAL VASCULAR DISEASE | peroxisome proliferator-activated receptor | HEMATOLOGY | gene expression | Dietary Fats - metabolism | Up-Regulation | Linoleic Acid - metabolism | Cardiomyopathies - prevention & control | Male | Cardiomyopathies - genetics | Angiopoietin-like 4 Protein | RNA Interference | Time Factors | Myocardium - metabolism | Dietary Fats - administration & dosage | PPAR delta - genetics | Cytoprotection | Animals, Newborn | Angiopoietins - metabolism | Oleic Acid - metabolism | PPAR delta - deficiency | PPAR-beta - metabolism | Mice, Inbred C57BL | Cells, Cultured | Oxidative Stress - genetics | Angiopoietins - deficiency | Dietary Fats - blood | Fatty Acids, Unsaturated - metabolism | PPAR-beta - genetics | PPAR-beta - deficiency | Mice, Knockout | Fatty Acids, Unsaturated - blood | Fatty Acids, Unsaturated - toxicity | Feedback, Physiological | Animals | Cardiomyopathies - metabolism | alpha-Linolenic Acid - metabolism | Mice | PPAR delta - metabolism | Angiopoietins - genetics | Lipid Peroxidation | Dietary Fats - toxicity | Cardiomyopathies - chemically induced | Fatty Acids, Unsaturated - administration & dosage
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2014, Volume 289, Issue 29, pp. 20102 - 20119
Endoplasmic reticulum (ER) stress and ER stress-associated unfolded protein response (UPR) can promote cancer cell survival, but it remains unclear whether... 
CELLS | CARCINOGENESIS | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIGNALING NETWORK | TRANSCRIPTION | INDUCED SKIN TUMORIGENESIS | DIFFERENTIATION | EXPRESSION | CANCER | LIGAND ACTIVATION | RNA, Small Interfering - genetics | Colonic Neoplasms - genetics | TOR Serine-Threonine Kinases - metabolism | Adenoma - genetics | Humans | Colonic Neoplasms - metabolism | Adenoma - metabolism | Gene Knockdown Techniques | Heat-Shock Proteins - genetics | Genes, p53 | Cell Transformation, Neoplastic - genetics | Proto-Oncogene Proteins c-akt - metabolism | PPAR delta - genetics | Skin Neoplasms - pathology | Cellular Senescence - genetics | Gene Expression | PPAR delta - deficiency | PPAR-beta - metabolism | Signal Transduction | Cells, Cultured | Activating Transcription Factor 4 - genetics | Cellular Senescence - physiology | Keratinocytes - cytology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | PPAR-beta - genetics | Unfolded Protein Response | Cell Transformation, Neoplastic - metabolism | PPAR-beta - deficiency | Regulatory Factor X Transcription Factors | Skin Neoplasms - metabolism | Animals | Keratinocytes - metabolism | Models, Biological | Colonic Neoplasms - pathology | Endoplasmic Reticulum Stress | Skin Neoplasms - genetics | Adenoma - pathology | Mice | PPAR delta - metabolism | Genes, ras | Index Medicus | Molecular Bases of Disease | Cancer Therapy | Keratinocyte | Cancer Biology | H-RAS-induced Senescence | Tumor Suppressor Gene | Peroxisome Proliferator-activated Receptor β | Cancer | Oncogene-induced Endoplasmic Reticulum Stress
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 135, Issue 6, pp. 1625 - 1635.e5
Background Remodeling of quiescent vessels with increases in permeability, vasodilatation, and edema are hallmarks of inflammatory disorders. Factors involved... 
Allergy and Immunology | Peroxisome proliferator-activated receptor β/δ | smooth muscle cells | endothelium | anaphylaxis | vascular permeability | SIGNALING PATHWAYS | NITRIC-OXIDE SYNTHASE | DELTA | MAST-CELLS | DIABETIC-RATS | IMMUNOLOGY | ALLERGY | INFLAMMATION | IN-VIVO | VE-CADHERIN | Peroxisome proliferator-activated receptor beta/delta | ADHERENS JUNCTIONS | PPAR-BETA/DELTA | Edema - genetics | Myocytes, Smooth Muscle - pathology | Capillary Permeability - drug effects | Capillary Permeability - immunology | Hypothermia - immunology | Intercellular Junctions - immunology | Hypothermia - pathology | Proto-Oncogene Proteins c-akt - genetics | Thrombin - pharmacology | Intercellular Junctions - pathology | Anaphylaxis - immunology | PPAR delta - immunology | Female | Mitogen-Activated Protein Kinases - immunology | Myocytes, Smooth Muscle - drug effects | Vascular Endothelial Growth Factor A - pharmacology | PPAR delta - genetics | Skin - pathology | Skin - immunology | PPAR delta - deficiency | Edema - immunology | Histamine - pharmacology | Signal Transduction | Anaphylaxis - pathology | Gene Expression Regulation | Mice, Transgenic | PPAR-beta - immunology | PPAR-beta - genetics | PPAR-beta - deficiency | Anaphylaxis - genetics | Endothelial Cells - immunology | Skin - blood supply | Animals | Proto-Oncogene Proteins c-akt - immunology | Intercellular Junctions - drug effects | Myocytes, Smooth Muscle - immunology | Mitogen-Activated Protein Kinases - genetics | Mice | Endothelial Cells - pathology | Edema - pathology | Hypothermia - genetics | Skin - drug effects | Endothelial Cells - drug effects | Mitogen-Activated Protein Kinases/genetics | Skin/blood supply | Endothelial Cells/drug effects | Endothelial Cells/immunology | Intercellular Junctions/immunology | PPAR delta/immunology | Skin/pathology | Intercellular Junctions/drug effects | Hypothermia/genetics | Capillary Permeability/drug effects | Life Sciences | PPAR delta/genetics | PPAR delta/deficiency | Hypothermia/immunology | Immunology | Anaphylaxis/genetics | Histamine/pharmacology | PPAR-beta/immunology | Myocytes, Smooth Muscle/pathology | Anaphylaxis/pathology | Myocytes, Smooth Muscle/immunology | Endothelial Cells/pathology | Hypothermia/pathology | Vascular Endothelial Growth Factor A/pharmacology | Mitogen-Activated Protein Kinases/immunology | Myocytes, Smooth Muscle/drug effects | Edema/immunology | Proto-Oncogene Proteins c-akt/genetics | Edema/pathology | Skin/immunology | Intercellular Junctions/pathology | Proto-Oncogene Proteins c-akt/immunology | Edema/genetics | PPAR-beta/genetics | Skin/drug effects | PPAR-beta/deficiency | Thrombin/pharmacology
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2011, Volume 31, Issue 3, pp. 574 - 581
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2006, Volume 103, Issue 50, pp. 19069 - 19074
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 07/2013, Volume 54, Issue 7, pp. 1949 - 1963
The surface of lipid droplets (LDs) in various cell types is coated with perilipin proteins encoded by the Plin genes. Perilipins regulate LD metabolism by... 
Perilipin | Lsdp5 | Plin | S3-12 | Plin3 | Plin4 | Plin2 | Plin5 | Promoter | Peroxisome proliferator-activated receptor response element | Oleic acid | Peroxisome proliferator-activated receptor δ | TIP47 | ADRP EXPRESSION | peroxisome proliferator-activated receptor response element promoter | HORMONE-SENSITIVE LIPASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | oleic acid | peroxisome proliferator-activated receptor delta | LIPID STORAGE DROPLETS | RESPONSE ELEMENT | perilipin | SKELETAL-MUSCLE | ADIPOCYTE LIPOLYSIS | INSULIN-RESISTANCE | DIFFERENTIATION-RELATED PROTEIN | DROPLET-ASSOCIATED PROTEIN | LIVER-X-RECEPTOR | PPAR delta - deficiency | Gene Silencing - drug effects | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Male | Muscle, Skeletal - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | Mice, Knockout | PPAR delta - chemistry | Muscle Proteins - genetics | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Muscle, Skeletal - drug effects | Muscle Proteins - metabolism | Fatty Acids - administration & dosage | RNA, Messenger - chemistry | Mice | Muscle Proteins - chemistry | PPAR delta - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Binding Sites - drug effects | Fatty Acids - pharmacology | peroxisome proliferator-activated receptor δ | promoter | peroxisome proliferator-activated receptor response element
Journal Article