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Nature, ISSN 0028-0836, 09/2011, Volume 477, Issue 7365, pp. 477 - 481
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2014, Volume 289, Issue 38, pp. 26618 - 26629
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2014, Volume 5, Issue 1, p. 3571
PPAR gamma is a target for insulin-sensitizing drugs such as glitazones, which improve plasma glucose maintenance in patients with diabetes. Synthetic ligands... 
INDEPENDENT MECHANISM | STRUCTURAL INSIGHT | ANDROGEN RECEPTOR | CONFORMATIONAL ENSEMBLE MODEL | COACTIVATOR-BINDING | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER CELLS | VITAMIN-D-RECEPTOR | FATTY-ACIDS | PROLIFERATOR-ACTIVATED-RECEPTOR | THYROID-HORMONE RECEPTOR | Ligands | PPAR gamma - metabolism | Binding Sites | PPAR gamma - chemistry
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2010, Volume 285, Issue 16, pp. 12321 - 12333
The peroxisome proliferator-activated receptor-gamma (PPAR gamma) binds diverse ligands to transcriptionally regulate metabolism and inflammation. Activators... 
OBESITY | INSULIN-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PPAR-GAMMA | GENERATION | MELLITUS | ROSIGLITAZONE | IDENTIFICATION | PROTEINS | THIAZOLIDINEDIONES | DERIVATIVES | Humans | Nitro Compounds - chemistry | Molecular Sequence Data | Male | Insulin - blood | PPAR gamma - metabolism | Tandem Mass Spectrometry | Oleic Acid - pharmacology | Base Sequence | DNA Primers - metabolism | Nitro Compounds - pharmacology | Thiazolidinediones - pharmacology | PPAR gamma - genetics | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Mutagenesis, Site-Directed | Signal Transduction | Mice, Inbred C57BL | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Recombinant Proteins - chemistry | Fatty Acids, Unsaturated - pharmacology | Lipid Metabolism | Hypoglycemic Agents - chemistry | Recombinant Proteins - genetics | 3T3-L1 Cells | Hypoglycemic Agents - pharmacology | Animals | Fatty Acids, Unsaturated - chemistry | PPAR gamma - agonists | Protein Binding | Ligands | Mice, Obese | Mice | Protein Processing, Post-Translational | Blood Glucose - metabolism | In Vitro Techniques | Oleic Acid - chemistry | Amino Acid Substitution | PPAR gamma - chemistry | Molecular Bases of Disease | Nitrated Fatty Acid | Oxidative Stress | Fatty Acid | Post-translational Modification | Michael Addition | PPARgamma | Diabetes | Nitric Oxide | Electrophile
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 08/2008, Volume 15, Issue 8, pp. 865 - 867
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e61755
Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a key regulator of glucose and lipid metabolism and therefore an important pharmacological... 
COMPLEX | LIGANDS | METABOLISM | AFFINITY | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | PPAR-GAMMA | BINDING | EXPRESSION | NUCLEAR RECEPTOR | INSIGHTS | Plant Extracts - chemistry | Deoxyglucose - metabolism | Plant Extracts - pharmacology | Humans | Polyacetylenes - chemistry | Transcriptional Activation - drug effects | Fatty Alcohols - chemistry | PPAR gamma - metabolism | Luciferases - genetics | Fatty Alcohols - pharmacology | Diynes - isolation & purification | HEK293 Cells | Fatty Alcohols - isolation & purification | Apiaceae - chemistry | Binding Sites | Genes, Reporter | Adipogenesis | Diynes - chemistry | Polyacetylenes - pharmacology | Plant Extracts - isolation & purification | 3T3-L1 Cells | Diynes - pharmacology | Animals | PPAR gamma - agonists | Protein Binding | Mice | Molecular Docking Simulation | Luciferases - biosynthesis | PPAR gamma - chemistry | Polyacetylenes - isolation & purification | Medicinal plants | Type 2 diabetes | Glucose metabolism | Luciferase | Medicine, Botanic | Dietary supplements | Medicine, Herbal | Glucose | Dextrose | Cell culture | Genomics | Lipids | Identification | Activation | Biochemistry | Adipocytes | Hydrophobicity | Hydrogen bonding | Chinese medicine | Hydrogen bonds | Metabolites | Docking | Lipid metabolism | Polyacetylene | Polyacetylenes | Pharmaceutical sciences | Food | Fractionation | Traditional Chinese medicine | Metabolic diseases | Inflammation | Pharmacology | Metabolism | Insulin | Plant extracts | Herbal medicine | Side effects | Diet | Plasmids | Pharmacy | Dichloromethane | Ligands | Binding sites
Journal Article
Journal Article