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Biochemical pharmacology, ISSN 0006-2952, 2014, Volume 92, Issue 1, pp. 73 - 89
Agonists of the nuclear receptor PPARγ are therapeutically used to combat hyperglycaemia associated with the metabolic syndrome and type 2 diabetes. In spite... 
Natural product | Nuclear receptor | Diabetes | Nutrition | PPAR gamma | INSULIN ACTION ENHANCER | NECROSIS-FACTOR-ALPHA | LOWERS BLOOD-PRESSURE | IMPROVES GLYCEMIC CONTROL | ADIPOCYTE DIFFERENTIATION | PHARMACOLOGY & PHARMACY | RED-CLOVER EXTRACT | GLUCOSE-UPTAKE | NF-KAPPA-B | LIVER-X-RECEPTOR | ADIPOSE-TISSUE | Biological Products - chemistry | Humans | PPAR gamma - agonists | Models, Molecular | Protein Binding | Biological Products - pharmacology | Molecular Structure | PPAR gamma - metabolism | Energy Metabolism - drug effects | DIO, diet-induced obesity | PPAR, peroxisome proliferator-activated receptor | TNF-α, tumor necrosis factor alpha | RXR, retinoid X receptor | CAP, c-Cbl-associated protein | DCM, dichloromethane | NF-κB, nuclear factor-kappaB | 9-(S)-HODE, (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid | AF-2, activation function-2 | Part of the Special Issue | MeOH, methanol | LDL, low-density lipoprotein | Cdk5, cyclin-dependent kinase 5 | DPP-4, dipeptidylpeptidase 4 | HUVEC, human umbilical vein endothelial cells | Glut4, glucose transporter type 4 | FDA, Food and Drug Administration | LBD, ligand-binding domain | EMA, European Medicines Agency | TCM, traditional Chinese medicine | PPRE, peroxisome proliferator response element | Metabolism 2014 – Alterations of metabolic pathways as therapeutic targets | PDB, protein data bank | SPPARMs, selective PPARγ modulators | HDL, high-density lipoprotein | MAPK, mitogen-activated protein kinase
Journal Article
Diabetes & Metabolic Syndrome: Clinical Research & Reviews, ISSN 1871-4021, 2015, Volume 9, Issue 1, pp. 46 - 50
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2017, Volume 357, Issue 6351, pp. 570 - 575
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2010, Volume 285, Issue 10, pp. 7153 - 7164
... gamma agonist rosiglitazone promotes not only the expression of PGC-1 alpha and mitochondriogenesis... 
SKELETAL-MUSCLE | NONSHIVERING THERMOGENESIS | FAT-CELLS | MITOCHONDRIAL BIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTIONAL CONTROL | UNCOUPLING PROTEIN-1 | GENE-EXPRESSION | ADULT HUMANS | COLD-ACCLIMATION | ADIPOSE-TISSUE | Adipocytes, White - cytology | Coculture Techniques | Ion Channels - genetics | Male | Epididymis - cytology | Mitochondrial Proteins - genetics | PPAR gamma - metabolism | Oxygen Consumption - physiology | Thermogenesis - physiology | Adipocytes, White - drug effects | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - genetics | Thiazolidinediones - pharmacology | Cell Differentiation - physiology | PPAR gamma - genetics | Biomarkers - metabolism | Adipocytes, Brown - drug effects | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Hypoglycemic Agents - pharmacology | Mice, Knockout | Adipocytes, White - physiology | Voltage-Dependent Anion Channels - genetics | Adipocytes, Brown - physiology | Animals | Ion Channels - metabolism | PPAR gamma - agonists | Trans-Activators - metabolism | Mice | Transcription Factors | Uncoupling Protein 1 | Adipocytes, Brown - cytology | Voltage-Dependent Anion Channels - metabolism | Adipocyte | Subcellular Organelles | UCP1 | Brown Adipocytes | Microscopic Imaging | PPARγ | Cell Biology | Receptors | Mitochondria | Nuclear | Mouse | Development Differentiation | Rosiglitazone | White Adipocytes
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Journal Article