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Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 62, pp. 416 - 425
The long-term use of levodopa (L-DOPA) in Parkinson's disease (PD) results in the development of abnormal involuntary movements called L-DOPA-induced... 
Cannabinoids | PPARα receptors | OEA | Capsaicin | Endocannabinoids
Journal Article
Journal of Veterinary Medical Science, ISSN 0916-7250, 2018
Expression of peroxisome proliferator-activated receptor (PPAR) α was investigated in adiponectin knockout mice to elucidate the relationship between PPARα and... 
PPARα | diabetes | Adiponectin
Journal Article
Diabetes & metabolism, ISSN 1262-3636, 06/2019
In hepatocytes, the peroxisome proliferator-activated receptor (PPAR)-α and insulin receptor (IR) are critical for transcriptional responses to fasting and... 
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2018, Volume 38, Issue 30, pp. 6682 - 6699
Journal Article
Biological Psychiatry, ISSN 0006-3223, 06/2019, Volume 85, Issue 12, pp. 1036 - 1045
The endocannabinoid and neurosteroid systems regulate emotions and stress responses. Activation of peroxisome proliferator-activated receptor (PPAR)-α by the... 
Fenofibrate | PTSD | Biomarkers | N-palmitoylethanolamine | PPAR-α | Allopregnanolone
Journal Article
Brain Research, ISSN 0006-8993, 02/2019, Volume 1704, pp. 47 - 58
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and are considered promising therapeutic targets in several neurodegenerative... 
Neuroinflammation | PPAR α/γ dual agonist | MPTP | MHY908 | Parkinson’s disease
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 05/2019, Volume 67, pp. 201 - 211
A better understanding of the mechanisms of beige and brown adipogenesis is needed for developing strategies to prevent and treat obesity and associated... 
Beige adipogenesis | Phytanic acid | Mitochondriogenesis | PPARα | Brown adipogenic differentiation
Journal Article
Basic & clinical pharmacology & toxicology, ISSN 1742-7835, 9/2017, Volume 121, Issue 3, pp. 169 - 174
Gemfibrozil, a peroxisome proliferator-activated receptor α (PPARα) agonist, is widely used for hypertriglyceridemia and mixed hyperlipidemia. Drug-drug... 
suppression | cytochrome P450 | PPARα | gemfibrozil
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 02/2019, Volume 300, pp. 123 - 130
The activation of hepatic stellate cells (HSCs) is a key event in the development of hepatic fibrosis caused by arsenic. However, it is unclear how arsenic... 
Hepatic stellate cells | Arsenic | PPARα | Autophagy | Fibrosis
Journal Article
Kidney International, ISSN 0085-2538, 05/2006, Volume 69, Issue 9, pp. 1511 - 1517
Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 07/2014, Volume 69, Issue 2, pp. 207 - 216
CKD-501 is a peroxisome proliferator-activated receptor (PPAR) agonist. The current study was conducted in Sprague Dawley (SD) rats for 94–101 weeks to... 
Carcinogenicity | CKD-501 | Dual PPARα/γ agonist
Journal Article
Hepatology (Baltimore, Md.), ISSN 0270-9139, 2/2014, Volume 59, Issue 2, pp. 695 - 704
Growth arrest and DNA damage-inducible beta (GADD45b) plays an important role in many intracellular events, such as cell cycle arrest, DNA repair, cell... 
GADD45b | PPARα | ACOX1 | STAT3
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 11/2019, Volume 133, pp. 110792 - 110792
Parabens are widely used as preservatives in personal care products, medicines and foods, resulting in substantial human exposures, even though some harmful... 
PXR | PPARα | Carboxylesterase | CAR | Nuclear receptor activation | Paraben | Index Medicus
Journal Article
Metabolism, ISSN 0026-0495, 01/2019, Volume 90, pp. 31 - 43
In metabolic disorders, adiponectin and adiponectin receptors (AdipoR1/R2) signaling has a key role in improving nonalcoholic fatty liver disease (NAFLD) in... 
AdipoR1/R2 | NAFLD | APPL1/PPAR-α/AMPK/SIRT1 pathways | Metabolic disorders | Osmotin | Adiponectin | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 01/2016, Volume 118, Issue 2, pp. 193 - 195
Journal Article
Journal of Clinical Biochemistry and Nutrition, ISSN 0912-0009, 2017
Soy isoflavone has benefits for metabolic syndrome but the mechanism is not completely understood. This study was designed to determine the effects of soy... 
NAFLD | soy isoflavone | PPARα | steatosis | SREBP-1c
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 12/2018, Volume 59, Issue 15, pp. 5803 - 5815
To determine if drug-induced peroxisome proliferator-activated receptor α (PPARα) signal pathway modulation affects refractive development and myopia in guinea... 
ApoA-II | Guinea pig | GW6471 | Myopia | ME1 | GW7647 | Fibrates | PPARα | Index Medicus
Journal Article
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