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by Li, S and Laher, I
Clinical pharmacology and therapeutics, 09/2017, Volume 102, Issue 3, p. 396
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 03/2016, Volume 16, Issue 3, pp. 173 - 186
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 12/2018, Volume 59, Issue 50, pp. 4384 - 4386
Peroxisome proliferator-activated receptor delta (PPARδ) is considered as a promising biological target for the development of new drugs to treat metabolic... 
GW501516 | d-Penicillamine | 4-Mercapto-2-methylphenol | PPAR agonists | TBAHS catalyst | D-Penicillamine | BETA/DELTA | DESIGN | PPAR-DELTA | GROWTH | CHEMISTRY, ORGANIC
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2019, Volume 29, Issue 3, pp. 503 - 508
We previously published on the design and synthesis of novel, potent and selective PPARα antagonists suitable for either i.p. or oral administration for the... 
PPAR alpha | Antagonist | Small molecule | PPAR delta | Cancer | CHEMISTRY, MEDICINAL | ACID | CHEMISTRY, ORGANIC
Journal Article
Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7592, pp. 53 - 58
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 09/2017, Volume 102, Issue 3, pp. 395 - 395
Journal Article
Biotechnology, ISSN 1682-296X, 2013, Volume 12, Issue 4, pp. 183 - 188
Journal Article
Cancer Cell, ISSN 1535-6108, 2004, Volume 6, Issue 3, pp. 285 - 295
Cyclooxygenase-derived prostaglandin E-2 (PGE(2)) is the predominant prostanoid found in most colorectal cancers (CRC) and is known to promote colon carcinoma... 
CARCINOGENESIS | CARCINOMA CELLS | ONCOLOGY | PPAR-DELTA | GENETIC DISRUPTION | POLYPOSIS | HUMAN COLON-CANCER | MICE | EXPRESSION | INTESTINAL EPITHELIAL-CELLS | CYCLOOXYGENASE-2 INHIBITOR
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2012, Volume 18, Issue 9, pp. 1350 - 1358
Journal Article
Nature Reviews Nephrology, ISSN 1759-5061, 06/2016, Volume 12, Issue 6, p. 313
Journal Article
Journal Article
Journal Article