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Free Radical Biology and Medicine, ISSN 0891-5849, 07/2017, Volume 108, pp. S82 - S82
Journal Article
Nature, ISSN 0028-0836, 12/2015, Volume 528, Issue 7580, pp. 137 - 141
Age-associated insulin resistance (IR) and obesity-associated IR are two physiologically distinct forms of adult-onset diabetes. While macrophage-driven... 
OBESITY | ORCHESTRATE DEVELOPMENT | VISCERAL ADIPOSE-TISSUE | RNA-SEQ | MACROPHAGES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | PPAR-GAMMA | DIFFERENTIATION | ACCUMULATION | BEIGE FAT
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 02/2019, Volume 79, Issue 3, pp. 445 - 451
Memory CD8(+) T cells (T-mem) are superior mediators of adoptive cell therapy (ACT) compared with effector CD8(+) T cells (T-eff) due to increased persistence... 
MEMORY | METABOLISM | ONCOLOGY | PATHWAY | PPAR-GAMMA | T-BET TRANSCRIPTION | EXPRESSION
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 09/2019, Volume 142, pp. 1 - 7
Recent studies using 3D scaffolds have emphasized the importance of the surrounding stroma on chemoresistance in drug efficacy screenings. Since... 
Interleukin 6 | 13-HpOTRE | PPAR gamma | 15-Lipoxygenase | Apoptosis | Cancer
Journal Article
Nature, ISSN 0028-0836, 03/2005, Volume 434, Issue 7029, pp. 113 - 118
Homeostatic mechanisms in mammals respond to hormones and nutrients to maintain blood glucose levels within a narrow range. Caloric restriction causes many... 
TRANSCRIPTION FACTORS | HEPATIC GLUCONEOGENESIS | LIFE-SPAN | REDOX STATE | METABOLISM | DEACETYLASE | MULTIDISCIPLINARY SCIENCES | COACTIVATOR PGC-1 | LIVER | PPAR-GAMMA | MICE
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2009, Volume 390, Issue 2, pp. 247 - 251
Obesity has emerged as a global health problem with more than 1.1 billion adults to be classified as overweight or obese, and is associated with type 2... 
microRNA | miR-27b | PPARγ | Adipogenesis | CELLS | OBESITY | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PPAR gamma | ADIPOSE-TISSUE
Journal Article
IMMUNITY, ISSN 1074-7613, 11/2016, Volume 45, Issue 5, pp. 975 - 987
Mononuclear phagocytes are a heterogeneous family that occupy all tissues and assume numerous roles to support tissue function and systemic homeostasis. Our... 
ACTIVATION | HOMEOSTASIS | TRANSCRIPTION FACTOR NR4A1 | CELL IDENTITY | IN-VIVO | NUR77 | PPAR-GAMMA | DIFFERENTIATION | IMMUNOLOGY | POLARIZATION | GENOME
Journal Article
05/2010
The acute phase of Trypanosoma cruzi infection is associated with a strong inflammatory reaction in the heart characterised by a massive infiltration of immune... 
15d-PGJ2 | Chagas disease | Trypanosoma cruzi | PPAR-gamma
Web Resource
ENDOCRINE-RELATED CANCER, ISSN 1351-0088, 12/2018, Volume 25, Issue 12, pp. L53 - L57
Journal Article
BIOMATERIALS, ISSN 0142-9612, 05/2012, Volume 33, Issue 15, pp. 3792 - 3802
The host response to biomaterials has been studied for decades. Largely, the interaction of host immune cells, macrophages in particular, with implanted... 
MATERIALS SCIENCE, BIOMATERIALS | Leukocyte | ENGINEERING, BIOMEDICAL | MUSCULAR-DYSTROPHY | NECROSIS-FACTOR-ALPHA | FOREIGN-BODY REACTION | SKELETAL-MUSCLE | HUMAN PERIPHERAL-BLOOD | INSULIN-RESISTANCE | Foreign body response | Biocompatibility | TUMOR-ASSOCIATED MACROPHAGES | PPAR-GAMMA | SPINAL-CORD-INJURY | Macrophage | ADIPOSE-TISSUE
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2010, Volume 392, Issue 3, pp. 323 - 328
microRNAs (miRNAs) are non-coding small RNAs regulating gene expression, cell growth, and differentiation. Although several miRNAs have been implicated in cell... 
Obesity | microRNA | miR-27a | PPARγ | Adipogenesis | ACTIVATED RECEPTOR-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | PREADIPOCYTES | PPAR gamma | DROSOPHILA | BIOPHYSICS | METABOLISM | INSULIN-RESISTANCE | GENE-EXPRESSION | ADIPOSE-TISSUE
Journal Article
American Journal of Epidemiology, ISSN 0002-9262, 03/2010, Volume 171, Issue 6, pp. 645 - 655
The peroxisome proliferator-activated receptor-γ gene ( PPARG ) has been implicated in the etiology of type 2 diabetes mellitus and has been investigated in... 
Genome, human | Diabetes mellitus, type 2 | Genetics | Review | Epidemiology | PPAR gamma | Meta-analysis | genome, human | epidemiology | genetics | review | meta-analysis | diabetes mellitus, type 2 | HUMAN GENOME EPIDEMIOLOGY (HuGE) REVIEW
Journal Article
Medical Science Monitor, ISSN 1234-1010, 2019, Volume 25, pp. 1582 - 1589
Journal Article
CELL STEM CELL, ISSN 1934-5909, 07/2012, Volume 11, Issue 1, pp. 50 - 61
Human bone marrow mesenchymal stem/stromal cells (MSCs) are multipotent progenitor cells with multilineage differentiation potentials including osteogenesis... 
JMJD3 | OSTEOBLASTOGENESIS | BONE-MARROW | TISSUE | GENE-EXPRESSION | PPAR-GAMMA | KAPPA-B | STROMAL CELLS | TRANSCRIPTIONAL REGULATION | MESENCHYMAL STEM-CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Hepatology, ISSN 0270-9139, 11/2008, Volume 48, Issue 5, pp. 1632 - 1643
The farnesoid X receptor (FXR) is a nuclear receptor that plays key roles in hepatoprotection by maintaining the homeostasis of liver metabolism. FXR null mice... 
LIVER-CANCER | ACUTE-PHASE RESPONSE | IN-VITRO | ACTIVATION | GLUCOCORTICOID-RECEPTOR | INDUCED APOPTOSIS | MOUSE MODEL | BILE-ACID HOMEOSTASIS | GENE-EXPRESSION | PPAR-GAMMA | GASTROENTEROLOGY & HEPATOLOGY
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 06/2019, Volume 203, Issue 3, pp. 658 - 664
Adipose regulatory T cells (aTregs) have emerged as critical cells for the control of local and systemic inflammation. In this study, we show a distinctive... 
EFFECTOR | ACTIVATION | INFLAMMATION | TISSUE | PPAR-GAMMA | ACCUMULATION | IMMUNOLOGY | E-PROTEIN | HYPOXIA
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2019, Volume 202, Issue 8, pp. 2451 - 2459
Macrophages, B cells, and adipocytes are among the adipose tissue (AT) APCs that differentiate and activate naive CD4(+) T cells. Mice with adipocyte loss of... 
RECRUITMENT | OBESITY | INSULIN-RESISTANCE | INFLAMMATION | REGULATORY T-CELLS | FAT | SENSITIVITY | PPAR-GAMMA | MICE | IMMUNOLOGY | INFILTRATION
Journal Article