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Biochemical Pharmacology, ISSN 0006-2952, 11/2014, Volume 92, Issue 1, pp. 73 - 89
Agonists of the nuclear receptor PPARγ are therapeutically used to combat hyperglycaemia associated with the metabolic syndrome and type 2 diabetes. In spite... 
Natural product | Nuclear receptor | Diabetes | Nutrition | PPAR gamma | NUCLEAR HORMONE RECEPTORS | INSULIN ACTION ENHANCER | NECROSIS-FACTOR-ALPHA | RANDOMIZED CONTROLLED-TRIAL | LIGAND-BINDING ACTIVITY | LOWERS BLOOD-PRESSURE | IMPROVES GLYCEMIC CONTROL | PHARMACOLOGY & PHARMACY | RETINOID-X-RECEPTOR | RED-CLOVER EXTRACT | NF-KAPPA-B | Biological Products - chemistry | Humans | PPAR gamma - agonists | Models, Molecular | Protein Binding | Biological Products - pharmacology | Molecular Structure | PPAR gamma - metabolism | Energy Metabolism - drug effects | DIO, diet-induced obesity | PPAR, peroxisome proliferator-activated receptor | TNF-α, tumor necrosis factor alpha | RXR, retinoid X receptor | CAP, c-Cbl-associated protein | DCM, dichloromethane | NF-κB, nuclear factor-kappaB | 9-(S)-HODE, (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid | AF-2, activation function-2 | Part of the Special Issue | MeOH, methanol | LDL, low-density lipoprotein | Cdk5, cyclin-dependent kinase 5 | DPP-4, dipeptidylpeptidase 4 | HUVEC, human umbilical vein endothelial cells | Glut4, glucose transporter type 4 | FDA, Food and Drug Administration | LBD, ligand-binding domain | EMA, European Medicines Agency | TCM, traditional Chinese medicine | PPRE, peroxisome proliferator response element | Metabolism 2014 – Alterations of metabolic pathways as therapeutic targets | PDB, protein data bank | SPPARMs, selective PPARγ modulators | HDL, high-density lipoprotein | MAPK, mitogen-activated protein kinase
Journal Article
Trends in Endocrinology & Metabolism, ISSN 1043-2760, 2012, Volume 23, Issue 5, pp. 205 - 215
Journal Article
Nature, ISSN 0028-0836, 09/2015, Volume 525, Issue 7569, pp. 380 - 383
Whether cancer is maintained by a small number of stem cells or is composed of proliferating cells with approximate phenotypic equivalency is a central... 
CANCER-CELLS | MAINTENANCE | ACTIVATION | HEMATOPOIESIS | PATHWAY | CITED2 | MULTIDISCIPLINARY SCIENCES | IMATINIB | STAT5 | DIFFERENTIATION | HIF-1-ALPHA | Piperazines - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Cell Proliferation | Neoplastic Stem Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | PPAR gamma - metabolism | Thiazolidinediones - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - pharmacology | STAT5 Transcription Factor - metabolism | Benzamides - administration & dosage | Thiazolidinediones - therapeutic use | Benzamides - therapeutic use | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neoplastic Stem Cells - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Neoplastic Stem Cells - pathology | Benzamides - pharmacology | Thiazolidinediones - pharmacology | Repressor Proteins - metabolism | Pyrimidines - administration & dosage | Piperazines - therapeutic use | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Pyrimidines - therapeutic use | PPAR gamma - agonists | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Trans-Activators - metabolism | Life Sciences | Microbiology and Parasitology | Immunology | Bacteriology | Virology
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 06/2009, Volume 109, Issue 6, pp. 1800 - 1811
Journal Article