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fatty acids (34) 34
gamma (34) 34
insulin-resistance (34) 34
oxidative stress (34) 34
ppar gamma - agonists (34) 34
nf-kappa-b (33) 33
peroxisome proliferator-activated receptor (33) 33
rats, sprague-dawley (33) 33
gene expression regulation (32) 32
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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2011, Volume 286, Issue 32, pp. 28382 - 28395
Bile acids (BAs) are powerful regulators of metabolism, and mice treated orally with cholic acid are protected from diet-induced obesity, hepatic lipid... 
SKELETAL-MUSCLE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BROWN ADIPOCYTES | GENE-EXPRESSION | ENZYMATIC-HYDROLYSIS | FARNESOID-X-RECEPTOR | LOW-DENSITY LIPOPROTEIN | WHITE FAT DEPOTS | DIETARY TAURINE | NUCLEAR RECEPTOR | ADIPOSE-TISSUE | Ion Channels | Rats, Wistar | Humans | Male | Metabolic Syndrome - metabolism | Muscle, Skeletal - metabolism | Mitochondrial Proteins | Metabolic Syndrome - blood | Angiopoietin-like 4 Protein | Dietary Proteins - pharmacology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Iodide Peroxidase - metabolism | Metabolic Syndrome - diet therapy | Female | Membrane Proteins - metabolism | Angiopoietins - metabolism | PPAR-beta - metabolism | Salmon | Heat-Shock Proteins - metabolism | Liver - metabolism | Rats | Bile Acids and Salts - metabolism | Triglycerides - metabolism | Transcription Factors - metabolism | Animals | Glucose - metabolism | Trans-Activators - metabolism | Adipose Tissue, Brown - metabolism | Mice | Uncoupling Protein 1 | Perilipin-2 | RNA-Binding Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Adipose Tissue Metabolism | Bile Acid | Obesity | Taurine | Amino Acid | Metabolic Syndrome | Diabetes | Metabolism | Peroxisome Proliferator-activated Receptor (PPAR) | Diet-induced Obesity | Medicinska grundvetenskaper | Basic Medicine
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 04/2018, Volume 46, Issue 1, pp. 187 - 202
Background/Aims: All-trans retinoic acid (ATRA) has protective effects against obesity and metabolic syndrome. We here aimed to gain further insight into the... 
Myokines | Obesity | AMPK | Muscle | PPARβ/δ | Nuclear receptors | Intramyocellular lipids | Retinoids/Vitamin A | Fatty acid/oxidation | PPAR beta/delta | PHYSIOLOGY | LIPID-METABOLISM | VITAMIN-A SUPPLEMENTATION | ACTIVATED RECEPTOR | CELL BIOLOGY | INSULIN-RESISTANCE | Retinoids/vitamin A | GENE-EXPRESSION | LEPTIN EXPRESSION | UNCOUPLING PROTEIN-3 | MICE | ADIPOSE-TISSUE | WHITE ADIPOCYTES | AMP-Activated Protein Kinases - metabolism | Liver - pathology | Male | Muscle, Skeletal - metabolism | Muscle, Skeletal - cytology | Fibroblast Growth Factors - metabolism | Liver - drug effects | PPAR-beta - agonists | Muscle, Skeletal - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | Fatty Acids - metabolism | Interleukin-6 - metabolism | Retinoid X Receptors - metabolism | Tretinoin - pharmacology | Neuropeptides - analysis | Cell Line | Enzyme-Linked Immunosorbent Assay | PPAR-beta - metabolism | Liver - metabolism | Neuropeptides - metabolism | Fibronectins - blood | Fibronectins - metabolism | Triglycerides - metabolism | Animals | Retinoid X Receptors - agonists | PPAR delta - agonists | Lipid Metabolism - drug effects | Glucose - metabolism | Fibronectins - genetics | Mice | Muscle, Skeletal - pathology | PPAR delta - metabolism | Liver | Homeostasis | Cytotoxicity | Lipids | Adipocytes | Glucose | Metabolism | Kinases | Fatty acids | Insulin | Proteins | Musculoskeletal system | Vitamin A | Antibiotics | Energy | Rodents | Oxidation | Diabetes | Index Medicus
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 01/2014, Volume 382, Issue 1, pp. 271 - 281
Journal Article
Endocrinology, ISSN 0013-7227, 05/2011, Volume 152, Issue 5, pp. 1848 - 1859
GW501516 amplifies the PGC-1α-lipin 1-PPARα pathway in liver, leading to increased fatty acid oxidation. Metabolic syndrome-associated dyslipidemia is mainly... 
DENSITY LIPOPROTEIN PRODUCTION | SKELETAL-MUSCLE | METABOLIC SYNDROME | GLUCOSE-METABOLISM | ENDOCRINOLOGY & METABOLISM | ALPHA | PROTEIN-KINASE ACTIVATION | RECEPTOR-DELTA | INSULIN SENSITIVITY | EXPRESSION | GENE-TRANSCRIPTION | AMP-Activated Protein Kinases - metabolism | Immunoblotting | PPAR gamma - metabolism | Liver - drug effects | PPAR-beta - agonists | Lipids - blood | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Dietary Fats - administration & dosage | Oxidation-Reduction - drug effects | Trans-Activators - genetics | Phosphorylation - drug effects | Nuclear Proteins - genetics | Fatty Acids - metabolism | Receptors, LDL - genetics | Dietary Fats - adverse effects | Glucose Tolerance Test | PPAR-beta - metabolism | Liver - metabolism | Receptors, LDL - metabolism | Hypertriglyceridemia - metabolism | Nuclear Proteins - metabolism | PPAR alpha - genetics | Down-Regulation - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Phosphatidate Phosphatase | Triglycerides - metabolism | Hypertriglyceridemia - prevention & control | Animals | Signal Transduction - drug effects | Hypertriglyceridemia - etiology | PPAR gamma - agonists | Trans-Activators - metabolism | Mice | Thiazoles - pharmacology | Transcription Factors | PPAR alpha - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2013, Volume 123, Issue 6, pp. 2564 - 2575
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e59726 - e59726
Journal Article
International Journal of Obesity, ISSN 0307-0565, 08/2007, Volume 31, Issue 8, pp. 1302 - 1310
Objective: To examine whether rosiglitazone alters gene expression of some key genes involved in mitochondrial biogenesis and oxidative capacity in skeletal... 
Insulin resistance | PGC-1α | Intramyocellular lipid | Metabolic flexibility | Thiazolidinediones | Skeletal muscle | thiazolidinediones | metabolic flexibility | PGC-1 alpha | MITOCHONDRIAL BIOGENESIS | LIPID-CONTENT | FATTY-ACID-METABOLISM | SENSITIVITY | GLYCOGEN | NUTRITION & DIETETICS | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | DYSFUNCTION | skeletal muscle | insulin resistance | intramyocellular lipid | Humans | Middle Aged | Mitochondria, Muscle - metabolism | Male | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Heat-Shock Proteins - genetics | Thiazolidinediones - therapeutic use | Insulin Resistance - physiology | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Diabetes Mellitus, Type 2 - etiology | Thiazolidinediones - pharmacology | Hypoglycemic Agents - therapeutic use | PPAR-beta - metabolism | Obesity - complications | Heat-Shock Proteins - metabolism | Transcription Factors - genetics | PPAR-beta - genetics | Hypoglycemic Agents - pharmacology | Obesity - metabolism | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Biopsy | Lipid Metabolism - drug effects | Muscle, Skeletal - pathology | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Lipid Metabolism - physiology | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 50, pp. 42195 - 42205
Retinoic acid (RA) regulates gene transcription by activating the nuclear receptors retinoic acid receptor (RAR) and peroxisome proliferator-activated receptor... 
LIM PROTEIN | STEM-CELLS | EMBRYONAL CARCINOMA-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | F9 TERATOCARCINOMA CELLS | REV-ERB-ALPHA | NEURONAL DIFFERENTIATION | KERATINOCYTES | EXPRESSION | BINDING PROTEIN-II | Sirtuin 1 - metabolism | Neurons - cytology | Fatty Acid-Binding Proteins - metabolism | LIM Domain Proteins - metabolism | Neoplasm Proteins - metabolism | Neural Stem Cells - cytology | Sirtuin 1 - genetics | Receptors, Retinoic Acid - genetics | Mice, Mutant Strains | Antineoplastic Agents - pharmacology | Neurogenesis - drug effects | Neurons - metabolism | Neoplasm Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Tretinoin - pharmacology | Cell Line | PPAR-beta - metabolism | Protein-Serine-Threonine Kinases - genetics | Receptors, Retinoic Acid - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Hippocampus - cytology | PPAR-beta - genetics | Fatty Acid-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Animals | Signal Transduction - drug effects | Neurogenesis - physiology | LIM Domain Proteins - genetics | Signal Transduction - physiology | Mice | Neural Stem Cells - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Transcription Regulation | Retinoid-binding Protein | Neurodifferentiation | Nuclear Receptors | Retinoid | Cell Biology
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 06/2016, Volume 110-111, pp. 25 - 36
Bacterial endotoxin lipopolysaccharide (LPS) activates inflammatory pathways, induces cytokine expression in the endothelium, augments reactive oxygen species... 
Endothelial dysfunction | ER stress | Oxidative stress | PPARβ/δ | NADPH oxidase | UCP2 | PPAR beta/delta | LIPID-METABOLISM | ENDOPLASMIC-RETICULUM STRESS | INDUCED OBESE MICE | NITRIC-OXIDE PRODUCTION | INSULIN-RESISTANCE | MITOCHONDRIAL DYSFUNCTION | PHARMACOLOGY & PHARMACY | RECEPTOR-BETA/DELTA | UP-REGULATION | MOLECULAR-MECHANISMS | Endothelium, Vascular - cytology | Inflammation - pathology | RNA, Small Interfering - genetics | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Male | Aorta - metabolism | PPAR gamma - metabolism | Reactive Oxygen Species - agonists | Cytochrome b Group - metabolism | PPAR-beta - agonists | NADPH Oxidases - genetics | PPAR gamma - genetics | NADH, NADPH Oxidoreductases - genetics | Endoplasmic Reticulum Stress - drug effects | PPAR-beta - metabolism | Signal Transduction | Endothelial Cells - metabolism | Thiophenes - pharmacology | Uncoupling Protein 2 - genetics | Reactive Oxygen Species - antagonists & inhibitors | PPAR gamma - antagonists & inhibitors | PPAR-beta - antagonists & inhibitors | Endothelium, Vascular - metabolism | Lipopolysaccharides - pharmacology | Inflammation - prevention & control | Mice | Aorta - cytology | RNA, Small Interfering - metabolism | Inflammation - chemically induced | Uncoupling Protein 2 - antagonists & inhibitors | Endoplasmic Reticulum Stress - genetics | Sulfones - pharmacology | NADH, NADPH Oxidoreductases - metabolism | Uncoupling Protein 2 - metabolism | Tissue Culture Techniques | Aorta - drug effects | Mice, Inbred C57BL | Gene Expression Regulation | Cytochrome b Group - genetics | PPAR-beta - genetics | Calcimycin - pharmacology | NADPH Oxidase 2 | NADPH Oxidase 1 | Membrane Glycoproteins - genetics | Animals | Endothelial Cells - cytology | PPAR gamma - agonists | Inflammation - genetics | Thiazoles - pharmacology | Primary Cell Culture | Nitric Oxide - metabolism | Endothelial Cells - drug effects | Index Medicus
Journal Article