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Molecular Cell, ISSN 1097-2765, 11/2019, Volume 76, Issue 3, pp. 423 - 436.e3
The Polycomb repressive complex 2 (PRC2) catalyzes H3K27 methylation across the genome, which impacts transcriptional regulation and is critical for... 
H3K27 methylation | PRC2 | transcription | PRC1 | polycomb | epigenetics | EZH2 | H3K27me3
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 01/2007, Volume 21, Issue 1, pp. 49 - 54
Genetic studies have demonstrated that Bmi1 promotes cell proliferation and stem cell self-renewal with a correlative decrease of p16 INK4a expression. Here,... 
pRB | p16 | PRC2 | BMI1 | PRC1 | transcriptional regulation | Research Communication
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2019, Volume 294, Issue 5, pp. 1451 - 1463
Journal Article
EXPERT OPINION ON THERAPEUTIC TARGETS, ISSN 1472-8222, 07/2019, Volume 23, Issue 7, pp. 565 - 578
Introduction: Epigenetic modifications are important regulators of transcription and appropriate gene expression answering an environmental stimulus. In... 
CHROMATIN | CBX2 | therapy | METHYLATED HISTONE H3 | E-CADHERIN | BMI1 | target | PRC1 COMPLEX | BREAST-CANCER | polycomb protein | CHROMOBOX PROTEIN | PRC2 | PRC1 | CELL SELF-RENEWAL | GENOME-WIDE | PHARMACOLOGY & PHARMACY | cancer | H2A UBIQUITYLATION | EZH2 | H3K27me3 | HEMATOPOIETIC STEM
Journal Article
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 07/2019, Volume 30, Issue 14, pp. 1691 - 1704
Oocytes of many species lack centrioles and therefore form acentriolar spindles. Despite the necessity of oocyte meiosis for successful reproduction, how these... 
ORGANIZATION | 1ST | PRC1 | KINASE | LENGTH | AURORA B | SPINDLE | CHROMOSOMES | CELL BIOLOGY
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 11/2018, Volume 1865, Issue 11, pp. 1630 - 1639
Cytokinesis begins in anaphase with the formation of the central spindle. PRC1 is a microtubule associated protein that plays an essential role in central... 
Multinucleation | p27Kip1 | Microtubule | PRC1 | Mitotic spindle | Cell cycle | p27 | Life Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2016, Volume 113, Issue 34, pp. 9430 - 9439
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 01/2007, Volume 21, Issue 1, pp. 49 - 54
Genetic studies have demonstrated that Bmi1 promotes cell proliferation and stem cell self-renewal with a correlative decrease of p16(INK4a) expression. Here,... 
TRANSFORMATION | pRB | BMI-1 | transcriptional regulation | SELF-RENEWAL | PROLIFERATION | DEVELOPMENTAL BIOLOGY | BMI1 | CELL-CYCLE CONTROL | CANCER | CELL BIOLOGY | p16 | PRC2 | PRC1 | GENETICS & HEREDITY | SENESCENCE | INHIBITORS | IMMORTALIZATION | EXPRESSION
Journal Article
Genes and Development, ISSN 0890-9369, 01/2019, Volume 33, Issue 1-2, pp. 4 - 5
All of the cells in our body share largely identical DNA, yet functionally distinct cells are generated to give rise to different tissues and organs. A... 
PRC2 | Polycomb complex | PRC1 | cell adhesion | skin | epigenetics | epidermis | GENETICS & HEREDITY | DEVELOPMENTAL BIOLOGY | CELL BIOLOGY | Outlook
Journal Article
CURRENT OPINION IN PLANT BIOLOGY, ISSN 1369-5266, 12/2016, Volume 34, pp. 41 - 53
Histone lysine methylation plays a fundamental role in the epigenetic regulation of gene expression in multicellular eukaryotes, including plants. It shapes... 
NAC TRANSCRIPTION FACTORS | REGULATE GENE-EXPRESSION | DNA METHYLATION | STRUCTURAL BASIS | ACTIVE TRANSCRIPTION | GENOME-WIDE ANALYSIS | FLOWERING-LOCUS-C | DOMAIN PROTEIN | H3K4 TRIMETHYLATION | PRC1 COMPLEX | PLANT SCIENCES
Journal Article
Cell Cycle, ISSN 1538-4101, 04/2019, Volume 18, Issue 8, pp. 773 - 783
SLC7A11 (or xCT) imports extracellular cystine into cells to promote glutathione synthesis, thus inhibiting ferroptosis. SLC7A11 expression is tightly... 
H2A ubiquitination | ferroptosis | SLC7A11 | PRC1 | BAP1 | COMPLEX | INHIBITION | TRANSPORTER GENE | CHECKPOINT | ANTIPORTER | POLYCOMB | CELL-DEATH | CELL BIOLOGY
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 07/2019, Volume 33, Issue 13-14, pp. 799 - 813
Mammalian development requires effective mechanisms to repress genes whose expression would generate inappropriately specified cells. The Polycomb-repressive... 
gene repression | development | COMPACTION | RNA | PHOSPHORYLATION | Polycomb-repressive complex | nucleosome compaction | DEVELOPMENTAL BIOLOGY | chromatin | FAMILY | CELL BIOLOGY | phase separation | PRC1 | HISTONE H3 | HETEROCHROMATIN | GENETICS & HEREDITY | TARGETS | PROTEINS
Journal Article