Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
pre-botzinger complex (823) 823
animals (626) 626
neurosciences (449) 449
index medicus (409) 409
physiology (364) 364
in-vitro (261) 261
respiration (256) 256
rats (249) 249
neurons (241) 241
prebotzinger complex (214) 214
respiratory rhythm generation (198) 198
neurons - physiology (193) 193
rhythm generation (178) 178
male (170) 170
humans (169) 169
mice (165) 165
pre-bötzinger complex (148) 148
respiratory system (147) 147
animals, newborn (145) 145
medulla oblongata - physiology (140) 140
rats, sprague-dawley (140) 140
brain-stem (139) 139
pacemaker neurons (133) 133
respiratory mechanics - physiology (130) 130
periodicity (126) 126
respiratory center - physiology (122) 122
article (114) 114
female (113) 113
in vitro techniques (102) 102
nerve net - physiology (102) 102
brain stem - physiology (99) 99
action potentials - physiology (98) 98
rat (97) 97
breathing (93) 93
respiratory rhythm (92) 92
neurons - drug effects (88) 88
motor neurons - physiology (81) 81
respiratory center - cytology (80) 80
neurons - metabolism (77) 77
rhythm (75) 75
medulla oblongata - cytology (74) 74
nervous system (72) 72
models, neurological (71) 71
respiratory center - drug effects (71) 71
persistent sodium current (69) 69
respiration - drug effects (69) 69
brain stem (67) 67
biological clocks - physiology (66) 66
medical education (64) 64
network (64) 64
infant-death-syndrome (63) 63
pulmonary/respiratory (62) 62
hypoxia (61) 61
rostral ventrolateral medulla (61) 61
spinal-cord (61) 61
brainstem (60) 60
medulla oblongata - drug effects (60) 60
patch-clamp techniques (60) 60
action potentials - drug effects (59) 59
central pattern generator (59) 59
rats, wistar (58) 58
central-nervous-system (57) 57
inspiratory neurons (57) 57
analysis (56) 56
neural networks (55) 55
neurology (54) 54
in-vivo (53) 53
neuroscience (52) 52
hypoxia - physiopathology (51) 51
synaptic inhibition (51) 51
brain (50) 50
neonatal-rat (50) 50
cat (49) 49
medulla (49) 49
respiratory physiological phenomena (49) 49
brain stem - drug effects (48) 48
mammals (48) 48
phrenic nerve - physiology (48) 48
electrophysiology (47) 47
expiratory neurons (47) 47
stem-spinal-cord (46) 46
brain stem - cytology (45) 45
inhalation - physiology (45) 45
retrotrapezoid nucleus (45) 45
ventrolateral medulla (45) 45
articles (44) 44
synaptic transmission - physiology (44) 44
modulation (43) 43
sport sciences (43) 43
models (42) 42
neurons - cytology (42) 42
control of breathing (41) 41
dose-response relationship, drug (41) 41
newborn rat (41) 41
newborn rats (41) 41
computer simulation (40) 40
hypoglossal nerve - physiology (39) 39
physiological aspects (39) 39
receptors (39) 39
spinal cord - physiology (39) 39
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Defining preBötzinger Complex Rhythm- and Pattern-Generating Neural Microcircuits In Vivo
by Cui, Yan and Kam, Kaiwen and Sherman, David and Janczewski, Wiktor A and Zheng, Yu and Feldman, Jack L
Neuron, ISSN 0896-6273, 08/2016, Volume 91, Issue 3, pp. 602 - 614
Normal breathing in rodents requires activity of glutamatergic Dbx1-derived (Dbx1 ) preBötzinger Complex (preBötC) neurons expressing somatostatin (SST). We... 
SYSTEM | RECEPTOR-IMMUNOREACTIVE NEURONS | TRANSMISSION | INHIBITION | SOMATOSTATIN | PRE-BOTZINGER COMPLEX | NEUROSCIENCES | INTERNEURONS | Interneurons - physiology | Neural Inhibition - physiology | Medulla Oblongata - cytology | Animals | Homeodomain Proteins - biosynthesis | Rhodopsin - biosynthesis | Mice, Transgenic | Mice | Respiration - genetics | Medulla Oblongata - physiology | Neural Pathways | Somatostatin - biosynthesis | Virus diseases | Medical colleges | Genetic engineering | Neurons | Analysis | Neurophysiology | Roles | Laboratories | Transgenic animals | Rodents
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Developmental origin of prebötzinger complex respiratory neurons
by Gray, Paul A and Hayes, John A and Ling, Guang Y and Llona, Isabel and Tupal, Srinivasan and Picardo, Maria Cristina D and Ross, Sarah E and Hirata, Tsutomu and Corbin, Joshua G and Eugenín, Jaime and Del Negro, Christopher A
Journal of Neuroscience, ISSN 0270-6474, 11/2010, Volume 30, Issue 44, pp. 14883 - 14895
A subset of preBotzinger Complex (preBotC) neurokinin 1 receptor (NK1R) and somatostatin peptide (SST)-expressing neurons are necessary for breathing in adult... 
SPINAL-CORD PREPARATION | GENETIC IDENTIFICATION | NEWBORN RAT | NEONATAL-RAT | PRE-BOTZINGER COMPLEX | RECEPTOR-EXPRESSING NEURONS | INSPIRATORY ACTIVITY | RHYTHM GENERATION | PACEMAKER NEURONS | NEUROSCIENCES | STEM IN-VITRO | Mice, Transgenic | Neurons - cytology | Respiratory Physiological Phenomena - genetics | Somatostatin - physiology | Receptors, Neurokinin-1 - physiology | Respiratory Center - cytology | Neural Stem Cells - cytology | Homeodomain Proteins - genetics | Neurogenesis - genetics | Receptors, Somatostatin - genetics | Cell Differentiation - genetics | Animals | Respiratory Center - drug effects | Respiratory Center - growth & development | Neurons - physiology | Receptors, Somatostatin - physiology | Mice | Homeodomain Proteins - physiology | Neurons - drug effects | Neural Stem Cells - metabolism | Somatostatin - metabolism | Organ Culture Techniques | Gene Expression Regulation, Developmental - physiology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Optogenetic perturbation of preBötzinger complex inhibitory neurons modulates respiratory pattern
by Sherman, David and Worrell, Jason W and Cui, Yan and Feldman, Jack L
Nature Neuroscience, ISSN 1097-6256, 03/2015, Volume 18, Issue 3, pp. 408 - 416
Inhibitory neurons make up a substantial fraction of the neurons in the preBotzinger complex (preBotC), a site that is critical for mammalian eupneic... 
SYNAPTIC INHIBITION | NETWORK | EXPIRATORY NEURONS | PRE-BOTZINGER COMPLEX | GENERATION | RHYTHM | LARYNGEAL CHEMOREFLEX | RECEPTORS | MEDULLA | NEUROSCIENCES | INTERNEURONS | Glycine - metabolism | Glycine Plasma Membrane Transport Proteins - metabolism | Action Potentials - genetics | Opsins - genetics | Channelrhodopsins | Male | Phosphopyruvate Hydratase - metabolism | Optogenetics | Neural Inhibition - physiology | Medulla Oblongata - cytology | Neurons - physiology | Respiration - genetics | Medulla Oblongata - physiology | Neural Inhibition - genetics | Microinjections | Mice, Inbred C57BL | Mice, Transgenic | Action Potentials - physiology | Glycine Plasma Membrane Transport Proteins - genetics | Animals | Opsins - metabolism | Luminescent Proteins - genetics | Mice | Photic Stimulation | Luminescent Proteins - metabolism | Physiological aspects | Research | Respiration | Neurons | inhibition | adeno-associated virus | breathing | preBötzinger Complex | optogenetics | respiratory rhythm
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Projections of preBötzinger Complex neurons in adult rats
by Tan, Wenbin and Pagliardini, Silvia and Yang, Paul and Janczewski, Wiktor A and Feldman, Jack L
Journal of Comparative Neurology, ISSN 0021-9967, 05/2010, Volume 518, Issue 10, pp. 1862 - 1878
The preBötzinger Complex (preBötC) contains neural microcircuitry essential for normal respiratory rhythm generation in rodents. A subpopulation of preBötC... 
AAV2 | breathing | preBötzinger Complex | respiratory rhythm | Breathing | Respiratory rhythm | Prebötzinger | Complex | RETROTRAPEZOID NUCLEUS | PERIAQUEDUCTAL GRAY | VENTRAL RESPIRATORY GROUP | KOLLIKER-FUSE NUCLEI | SPINAL-CORD | TOPOGRAPHIC ORGANIZATION | NEUROSCIENCES | ZOOLOGY | PRE-BOTZINGER COMPLEX | IN-VIVO | preBotzinger Complex | CENTRAL-NERVOUS-SYSTEM | SUBSTANCE-P RECEPTOR | Dependovirus - genetics | Green Fluorescent Proteins - metabolism | Promoter Regions, Genetic | Somatostatin - genetics | Dependovirus - metabolism | Receptors, G-Protein-Coupled - metabolism | Fluorescent Dyes - metabolism | Rats | Receptors, Neuropeptide - genetics | Male | Neurons - cytology | Receptors, Neuropeptide - metabolism | Green Fluorescent Proteins - genetics | Respiratory Center - cytology | Drosophila Proteins - metabolism | Rats, Sprague-Dawley | Neural Pathways - anatomy & histology | Animals | Neurons - metabolism | Receptors, G-Protein-Coupled - genetics | Drosophila Proteins - genetics | Respiratory Center - physiology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Silencing preBötzinger Complex somatostatin-expressing neurons induces persistent apnea in awake rat
by Tan, Wenbin and Janczewski, Wiktor A and Yang, Paul and Shao, Xuesi M and Callaway, Edward M and Feldman, Jack L
Nature Neuroscience, ISSN 1097-6256, 05/2008, Volume 11, Issue 5, pp. 538 - 540
Delineating neurons that underlie complex behaviors is of fundamental interest. Using adeno-associated virus 2, we expressed the Drosophila allatostatin... 
PRE-BOTZINGER COMPLEX | RECEPTOR | MAMMALIAN NEURONS | RHYTHM | NEUROSCIENCES | DROSOPHILA | REGION | Dependovirus - genetics | Apnea - physiopathology | Green Fluorescent Proteins - genetics | Nerve Net - drug effects | Biological Clocks - drug effects | Drosophila Proteins - biosynthesis | Nerve Net - cytology | Respiratory Center - drug effects | Transfection - methods | Neuropeptides - pharmacology | Receptors, Neurokinin-1 - metabolism | Neurons - metabolism | Neurons - drug effects | Receptors, Neuropeptide - biosynthesis | Somatostatin - metabolism | Biomarkers - metabolism | Neural Inhibition - genetics | Drosophila | Periodicity | Rats | Receptors, Neuropeptide - genetics | Receptors, G-Protein-Coupled - biosynthesis | Respiratory Center - cytology | Respiratory Center - metabolism | Respiratory Physiological Phenomena | Animals | Biological Clocks - genetics | Nerve Net - metabolism | Wakefulness - physiology | Apnea - genetics | Receptors, G-Protein-Coupled - genetics | Drosophila Proteins - genetics | Genetic Vectors | Apnea - chemically induced | Neural Inhibition - drug effects | Apnea | Neurons | Physiological aspects | Genetic aspects | Research | Somatostatin | Risk factors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Genetic identification of an embryonic parafacial oscillator coupling to the preBötzinger complex
by Thoby-Brisson, Muriel and Karlén, Mattias and Wu, Ning and Charnay, Patrick and Champagnat, Jean and Fortin, Gilles
Nature Neuroscience, ISSN 1097-6256, 08/2009, Volume 12, Issue 8, pp. 1028 - 1035
The hindbrain transcription factors Phox2b and Egr2 (also known as Krox20) are linked to the development of the autonomic nervous system and rhombomere-related... 
NERVOUS-SYSTEM | IN-VITRO | NEONATAL-RAT | PRE-BOTZINGER COMPLEX | DEVELOPING HINDBRAIN | NEURONS | FATAL CENTRAL APNEA | CONGENITAL CENTRAL HYPOVENTILATION | RESPIRATORY RHYTHM GENERATION | NEUROSCIENCES | MOUSE EMBRYO | Nerve Net - embryology | Reticular Formation - embryology | Early Growth Response Protein 2 - genetics | Homeodomain Proteins - metabolism | Brain Stem - metabolism | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | Respiratory Physiological Phenomena - genetics | Stem Cells - cytology | Stem Cells - metabolism | Brain Stem - cytology | Nerve Net - cytology | Neurogenesis - genetics | Cell Differentiation - genetics | Reticular Formation - metabolism | Inhalation - genetics | Mice, Inbred DBA | Neurons - metabolism | Mice, Inbred C57BL | Periodicity | Mice, Transgenic | Respiratory Center - cytology | Respiratory Center - metabolism | Transcription Factors - genetics | Respiratory Center - embryology | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Animals | Reticular Formation - cytology | Biological Clocks - genetics | Nerve Net - metabolism | Brain Stem - embryology | Early Growth Response Protein 2 - metabolism | Mice | Circadian rhythms | Neurons | Physiological aspects | Genetic aspects | Research | DNA binding proteins | Respiratory physiology | Life Sciences | Neurons and Cognition
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text PreBötzinger complex neurokinin-1 receptor-expressing neurons mediate opioid-induced respiratory depression
by Montandon, Gaspard and Qin, Wuxuan and Liu, Hattie and Ren, Jun and Greer, John J and Horner, Richard L
Journal of Neuroscience, ISSN 0270-6474, 01/2011, Volume 31, Issue 4, pp. 1292 - 1301
The analgesic properties of the opium poppy Papever somniferum were first mentioned by Hippocrates around 400 BC, and opioid analgesics remain the mainstay of... 
IN-VITRO | SLEEP | RAT BRAIN-STEM | NEONATAL-RAT | VIVO | PRE-BOTZINGER COMPLEX | MECHANISMS | MUSCLE-ACTIVITY | NEUROSCIENCES | REGION | ANALGESIA | Respiratory Rate - drug effects | Brain Stem - metabolism | Periodicity | Depression, Chemical | Rats | Male | Receptors, Opioid, mu - agonists | Rats, Sprague-Dawley | Brain Stem - drug effects | Synaptic Transmission | Analgesics, Opioid - adverse effects | Animals | Sleep | Respiration - drug effects | Neurons - physiology | Receptors, Neurokinin-1 - biosynthesis | Anesthesia | In Vitro Techniques | Apnea - chemically induced | Medulla Oblongata - physiology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Glycinergic Pacemaker Neurons in PreBotzinger Complex of Neonatal Mouse
by Morgado-Valle, Consuelo and Baca, Serapio M and Feldman, Jack L
Journal of Neuroscience, ISSN 0270-6474, 03/2010, Volume 30, Issue 10, pp. 3634 - 3639
The preBotzinger complex (preBotC) is essential for normal respiratory rhythm generation in rodents, for which the underlying mechanisms remain unknown.... 
SYNAPTIC INHIBITION | IN-VITRO | NETWORK | NMDA RECEPTORS | RAT | MEDULLARY SLICES | PRE-BOTZINGER COMPLEX | RESPIRATORY RHYTHM GENERATION | EXPRESSING NEURONS | NEUROSCIENCES | MODULATION | Animals, Newborn | Medulla Oblongata - metabolism | Mice, Transgenic | Respiratory Center - cytology | Respiratory Center - metabolism | Neurons - classification | Medulla Oblongata - cytology | Animals | Biological Clocks - physiology | Glycine - physiology | Biological Clocks - genetics | Neurons - physiology | Mice | Neurons - metabolism | Glycine Plasma Membrane Transport Proteins - physiology | Medulla Oblongata - physiology | Respiratory Center - physiology | Brief Communications
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Transcriptome of neonatal preBötzinger complex neurones in Dbx1 reporter mice
by Hayes, John A and Kottick, Andrew and Picardo, Maria Cristina D and Halleran, Andrew D and Smith, Ronald D and Smith, Gregory D and Saha, Margaret S and Del Negro, Christopher A
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 8669 - 13
We sequenced the transcriptome of brainstem interneurons in the specialized respiratory rhythmogenic site dubbed preBotzinger Complex (preBotC) from newborn... 
RECEPTOR-IMMUNOREACTIVE NEURONS | EXPRESSING CELLS | RETT-SYNDROME | HOMEOBOX GENE PHOX2B | VENTRAL MEDULLA | NONCODING RNAS | MULTIDISCIPLINARY SCIENCES | PRE-BOTZINGER COMPLEX | SPINAL-CORD | FATAL CENTRAL APNEA | RESPIRATORY RHYTHM GENERATION | Neonates | Transcription factors | Interneurons | Opioid receptors | Narcotics | Brain stem | Therapeutic applications | Dbx1 protein | Chemoreception | Gene expression | Developmental stages | Neural networks | Hypoxia | Respiration | Pax8 protein
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Inspiratory bursts in the preBötzinger complex depend on a calcium‐activated non‐specific cation current linked to glutamate receptors in neonatal mice
by Pace, Ryland W and Mackay, Devin D and Feldman, Jack L and Del Negro, Christopher A
The Journal of Physiology, ISSN 0022-3751, 07/2007, Volume 582, Issue 1, pp. 113 - 125
Inspiratory neurons of the preBötzinger complex (preBötC) form local excitatory networks and display 10–30 mV transient depolarizations, dubbed inspiratory... 
SIGNALING PATHWAYS | PHYSIOLOGY | AMPA RECEPTORS | NEURONS IN-VITRO | PRE-BOTZINGER COMPLEX | NETWORK ACTIVITY | BRAIN-STEM | PERSISTENT SODIUM CURRENT | RESPIRATORY RHYTHM GENERATION | PACEMAKER NEURONS | EXCITATORY AMINO-ACIDS | Receptors, Glutamate - metabolism | Flufenamic Acid - pharmacology | Calcium - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Receptors, Metabotropic Glutamate - metabolism | Receptors, Glutamate - drug effects | Action Potentials | Inhalation - physiology | Respiratory Center - drug effects | Synapses - metabolism | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Egtazic Acid - analogs & derivatives | Receptor, Metabotropic Glutamate 5 | Synaptic Transmission - drug effects | Neurons - metabolism | Neurons - drug effects | Calcium Signaling | Receptors, AMPA - metabolism | Animals, Newborn | Synapses - drug effects | Mice, Inbred C57BL | Periodicity | Chelating Agents - pharmacology | Respiratory Center - cytology | Respiratory Center - metabolism | Animals | Egtazic Acid - pharmacology | Glutamic Acid - metabolism | Mice | Kinetics | In Vitro Techniques | Inositol 1,4,5-Trisphosphate - metabolism | Inhalation - drug effects | Infants (Newborn) | Neuroscience
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Distinct inspiratory rhythm and pattern generating mechanisms in the preBötzinger Complex
by Kam, Kaiwen and Worrell, Jason W and Janczewski, Wiktor A and Cui, Yan and Feldman, Jack L
Journal of Neuroscience, ISSN 0270-6474, 05/2013, Volume 33, Issue 22, pp. 9235 - 9245
In the mammalian respiratory central pattern generator, the preBotzinger complex (preBotC) produces rhythmic bursts that drive inspiratory motor output.... 
RESPIRATORY RHYTHM | IN-VITRO | PERSISTENT SODIUM | RAT | MODELS | PRE-BOTZINGER COMPLEX | NEURAL-NETWORK | PACEMAKER NEURONS | EXPRESSING NEURONS | AUGMENTED BREATHS | NEUROSCIENCES | Animals, Newborn | Data Interpretation, Statistical | Motor Neurons - physiology | Central Pattern Generators - physiology | Mice, Inbred C57BL | Cadmium - pharmacology | Male | Bicuculline - pharmacology | Potassium - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Respiratory Mechanics - drug effects | Patch-Clamp Techniques | Animals | Analysis of Variance | Female | Mice | Respiratory Center - physiology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Neuroanatomical characteristics of the human pre-Bötzinger complex and its involvement in neurodegenerative brainstem diseases
by Schwarzacher, Stephan W and Rüb, Udo and Deller, Thomas
Brain, ISSN 0006-8950, 2011, Volume 134, Issue 1, pp. 24 - 35
The pre-Botzinger complex has been identified as an essential part of the medullary respiratory network in mammals. Although well described in experimental... 
respiratory control | brainstem | multiple system atrophy | spinocerebellar ataxia | pre-Bötzinger complex | SLEEP | RAT | INFANT-DEATH-SYNDROME | EXPRESSING NEURONS | NEUROSCIENCES | CLINICAL NEUROLOGY | PREBOTZINGER COMPLEX | NUCLEI | MACHADO-JOSEPH-DISEASE | pre-Botzinger complex | RHYTHM | Immunohistochemistry | Neurons - pathology | Multiple System Atrophy - pathology | Cell Count | Humans | Middle Aged | Male | Spinocerebellar Ataxias - physiopathology | Spinocerebellar Ataxias - metabolism | Spinocerebellar Ataxias - pathology | Multiple System Atrophy - metabolism | Neurons - physiology | Aged, 80 and over | Female | Medulla Oblongata - pathology | Receptors, Neurokinin-1 - metabolism | Aged | Multiple System Atrophy - physiopathology | Respiration | Medulla Oblongata - physiology | Somatostatin - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Phosphatidylinositol 4,5‐bisphosphate regulates inspiratory burst activity in the neonatal mouse preBötzinger complex
by Crowder, Erin A and Saha, Margaret S and Pace, Ryland W and Zhang, Honglu and Prestwich, Glenn D and Del Negro, Christopher A
The Journal of Physiology, ISSN 0022-3751, 08/2007, Volume 582, Issue 3, pp. 1047 - 1058
Neurons of the preBötzinger complex (preBötC) form local excitatory networks and synchronously discharge bursts of action potentials during the inspiratory... 
HYPERPOLARIZATION-ACTIVATED CURRENT | PHYSIOLOGY | NONSELECTIVE CATION CHANNEL | POTASSIUM CURRENTS | RAT | PRE-BOTZINGER COMPLEX | TRP CHANNELS | NEURONS | RECEPTOR | ION CHANNELS | RESPIRATORY RHYTHM GENERATION | Animals, Newborn | Gene Expression Regulation, Enzymologic - drug effects | Hypoglossal Nerve - physiology | Motor Neurons - physiology | Mice, Inbred C57BL | Electrophysiology | Glyceraldehyde-3-Phosphate Dehydrogenases - genetics | Reverse Transcriptase Polymerase Chain Reaction | Kidney | RNA - genetics | Action Potentials - physiology | Inhalation - physiology | RNA - isolation & purification | Animals | Phosphatidylinositol 4,5-Diphosphate - pharmacology | Mice | Action Potentials - drug effects | Motor Neurons - drug effects | Infants (Newborn) | Related Papers
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights