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Journal Article
Biological Psychiatry, ISSN 0006-3223, 2015, Volume 77, Issue 5, pp. 475 - 487
Abstract Background Mixed cannabinoid receptor 1 and 2 (CB1 and CB2 ) agonists such as Δ9 -tetrahydrocannabinol (Δ9 -THC) can produce tolerance, physical... 
Psychiatry | Tolerance | CB2 | Precipitated withdrawal | Chemotherapy-induced neuropathic pain | Knockout mouse | Side effect | DORSAL-HORN NEURONS | MECHANICAL ALLODYNIA | PSYCHIATRY | VENTRAL ROOT TRANSECTION | CB2 RECEPTOR | INDUCED PERIPHERAL NEUROPATHY | SPINAL-CORD | NECROSIS-FACTOR-ALPHA | NERVE INJURY | NEUROSCIENCES | ACID AMIDE HYDROLASE | PRIMARY SENSORY NEURONS | Hyperalgesia - chemically induced | Tumor Necrosis Factor-alpha - metabolism | Spinal Cord - drug effects | Receptor, Cannabinoid, CB2 - agonists | Male | Cannabinoid Receptor Agonists - pharmacology | RNA, Messenger - metabolism | Receptor, Cannabinoid, CB2 - genetics | Paclitaxel - toxicity | Receptor, Cannabinoid, CB1 - agonists | Cannabinoid Receptor Antagonists - pharmacology | Female | Indoles - pharmacology | Chemokine CCL2 - metabolism | Chromones - pharmacology | Dronabinol - pharmacology | Disease Models, Animal | Mice, Inbred C57BL | Random Allocation | Hyperalgesia - physiopathology | Mice, Knockout | Antineoplastic Agents, Phytogenic - toxicity | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Receptor, Cannabinoid, CB1 - genetics | Hyperalgesia - drug therapy | Spinal Cord - physiopathology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Cannabinoids | Neurosciences | Paclitaxel
Journal Article
by Wang, X and Liu, JB and Zhou, LN and Ho, WZ
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 11/2019, Volume 10, p. 2601
Opioid withdrawal recurs at high rates in opioid use disorder and compromises the immune system. In general, there are two types of opioid withdrawal: abrupt... 
abrupt withdrawal | microRNAs | MECHANISM | MX2 | precipitated withdrawal | OPIOIDS | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | morphine | macrophages | INHIBITION | HIV | CELLULAR MICRORNA | DNA | EXPRESSION | Morphine | Disease susceptibility | HIV (Viruses) | Macrophages | Health aspects | HIV infection
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2014, Volume 171, Issue 3, pp. 688 - 700
Background and Purpose The negative affective states of withdrawal involve the recruitment of brain and peripheral stress circuitry [noradrenergic activity,... 
NA turnover | CRF1 receptor knockout mice | naloxone‐precipitated morphine withdrawal | Hsp 27 | heart | receptor knockout mice | naloxone-precipitated morphine withdrawal | CRF | SYSTEM | PHOSPHORYLATION | HEAT-SHOCK-PROTEIN | RESPONSES | HORMONE | CARDIOVASCULAR FUNCTION | PHARMACOLOGY & PHARMACY | STRESS | PITUITARY-ADRENAL AXIS | BRAIN | HYPOTHALAMUS | Phosphorylation | Adrenergic Neurons - metabolism | Receptors, Corticotropin-Releasing Hormone - metabolism | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Mice, 129 Strain | Tachycardia - etiology | Hypertension - etiology | Morphine Dependence - physiopathology | Hypothalamo-Hypophyseal System - physiopathology | Disease Models, Animal | Pituitary-Adrenal System - physiopathology | Signal Transduction | Pituitary-Adrenal System - metabolism | Nerve Tissue Proteins - genetics | Corticotropin-Releasing Hormone - metabolism | Hypothalamo-Hypophyseal System - metabolism | Mice, Knockout | Nerve Tissue Proteins - metabolism | Morphine Dependence - metabolism | Animals | Naloxone | Heart Ventricles - physiopathology | HSP27 Heat-Shock Proteins - metabolism | Heart Ventricles - innervation | Heart Ventricles - metabolism | Mice | Protein Processing, Post-Translational | Proteins | Corticotropin releasing hormone | Corticosterone | Genetically modified organisms | ACTH | Heat shock proteins | Morphine | Genetic engineering | Medical research | Rodents | Research Papers
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 11/2017, Volume 9, Issue 11, pp. 1521 - 1536
Opiate withdrawal/negative reinforcement has been implicated as one of the mechanisms for the progression from impulsive to compulsive drug use. Increase in... 
naloxone‐precipitated opiate withdrawal | lentivirus injection | opiate addiction | locus coeruleus | Src‐mediated phosphorylation of MOR at Tyr336 | naloxone-precipitated opiate withdrawal | Src-mediated phosphorylation of MOR at Tyr | Neuroscience
Journal Article
Journal Article