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Journal of Clinical Investigation, ISSN 0021-9738, 06/2013, Volume 123, Issue 6, pp. 2523 - 2538
...). ADAM 10 also plays a critical role in regulating functional membrane proteins at the synapse... 
ALPHA-SECRETASE | DENDRITIC SPINES | MEDICINE, RESEARCH & EXPERIMENTAL | GLUTAMATE RECEPTORS | IDENTIFIES VARIANTS | AMPA RECEPTORS | LONG-TERM DEPRESSION | A-BETA | CELL-SURFACE | AMYLOID PRECURSOR PROTEIN | GENOME-WIDE ASSOCIATION | Amyloid Precursor Protein Secretases - genetics | Humans | Cercopithecus aethiops | Molecular Sequence Data | Fatty Acid-Binding Proteins - metabolism | Alzheimer Disease - pathology | Endocytosis | Amyloid beta-Protein Precursor - metabolism | Hippocampus - enzymology | Membrane Proteins - metabolism | Protein Interaction Domains and Motifs | Amino Acid Sequence | ADAM Proteins - chemistry | Membrane Proteins - genetics | ADAM10 Protein | Models, Molecular | Synapses - enzymology | Alzheimer Disease - enzymology | Amyloid Precursor Protein Secretases - chemistry | Long-Term Synaptic Depression | Amino Acid Motifs | Protein Interaction Mapping | Protein Transport | Cell Membrane - enzymology | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Animals | Membrane Proteins - chemistry | Neuronal Plasticity | Long-Term Potentiation | Protein Binding | Fatty Acid-Binding Proteins - chemistry | Mice | ADAM Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | COS Cells | Neuroplasticity | Physiological aspects | Development and progression | Genetic aspects | Research | Metalloenzymes | Alzheimer's disease | Proteins | Software | Alzheimers disease | Experiments | Cell Membrane | Fatty Acid-Binding Proteins | Life Sciences | Neuroscience | Amyloid Precursor Protein Secretases | Cognitive science | Biochemistry, Molecular Biology | ADAM Proteins | Alzheimer Disease | Membrane Proteins | Adaptor Proteins, Signal Transducing | Hippocampus | Synapses | Amyloid beta-Protein Precursor
Journal Article
Biochemical journal, ISSN 1470-8728, 2015, Volume 467, Issue 3, pp. 365 - 386
.... The CRLs assemble into functional multisubunit complexes using a repertoire of substrate receptors, adaptors, Cullin scaffolds and RING-box proteins... 
Ubiquitin | Ubiquitination | Small molecule | Structure | Structure-based design | Assembly | small molecule | ANAPHASE-PROMOTING COMPLEX | SOCS-BOX | BIOCHEMISTRY & MOLECULAR BIOLOGY | F-BOX PROTEINS | KAPPA-B-ALPHA | structure | structure-based design | ubiquitin | CANCER-THERAPY | ubiquitination | COP9 SIGNALOSOME | assembly | TUMOR-SUPPRESSOR PROTEIN | SUBSTRATE-ASSISTED INHIBITION | CELL-CYCLE | PROTEASOME SYSTEM | Protein Structure, Tertiary | Protein Subunits | Cullin Proteins - antagonists & inhibitors | Proteasome Inhibitors - pharmacology | Humans | Models, Molecular | Proteasome Inhibitors - chemistry | Drug Discovery - methods | Cullin Proteins - chemistry | Cullin Proteins - genetics | Drug Design | Protein Structure, Quaternary | Molecular Structure | MEL26, maternal effect lethal 26 | HECT, homologous with E6-associated protein C-terminus | DCAF, DDB1–Cul4A-associated factor | CPH, conserved within Cul7, PARC and HERC2 | CSA, Cockayne syndrome A | NAE, NEDD8-activating enzyme | Rbx1, RING-box protein 1 | PPI, protein–protein interaction | C, anaphase-promoting complex | SV5, simian virus 5 | Fbxw, F-box | Skp2, S-phase kinase-associated protein 2 | IAA, indole-3-acetic acid | Cpd, compound | Fbw | SMER3, small-molecule enhancer of rapamycin 3 | mTOR, mammalian target of rapamycin | HERC2, HECT domain- and RLD (regulator of chromosome condensation 1 protein-like domain) domain-containing E3 ubiquitin protein ligase 2 | IκB, inhibitor of NF-κB | UPS, ubiquitin–proteasome system | Nrf2, nuclear factor-erythroid 2-related factor 2 | Protac, proteolysis-targeting chimaeric molecule | WD repeat-containing protein | ZIM (zinc finger expressed in inflorescence) domain protein 1 | NF-κB, nuclear factor κB | leucine-rich motif-containing protein | CTD, C-terminal domain | Ub, ubiquitin | Vif, virion infectivity factor | NTD, N-terminal domain | GHR, growth hormone receptor | CRBN, cereblon | HIF-1α, hypoxia-inducible factor 1α | SH2, Src homology 2 | BP, β-propeller | UBL, ubiquitin-like protein | FP, fluorescence polarization | Cks1, cyclin-dependent protein kinase regulatory subunit 1 | CSN, COP9 (constitutive photomorphogenesis 9) signalosome complex | ITC, isothermal titration calorimetry | RING, really interesting new gene | Ubc12, ubiquitin-conjugating enzyme 12 | KLHL, Kelch-like protein | Review | VPRBP, Vpr-binding protein | SCF, Skp1–Cdc53–F-box Cdc4 | POZ, pox virus and zinc finger | JAZ1, jasmonate | Keap1, Kelch-like enoyl-CoA hydratase-associated protein 1 | PARC, p53-associated parkin-like cytoplasmic protein | DDB, damage-specific DNA-binding protein | JA-Ile, jasmonoyl-isoleucine | Fbxl, F-box | MATH, meprin and TRAF (tumour necrosis factor receptor-associated factor) homology | CRL, Cullin–RING E3 ubiquitin ligase | other domain-containing protein | COI1, coronatine-insensitive protein 1 | EloBC, ElonginB–ElonginC complex | broad complex | VHL, von Hippel–Lindau | Vpr, viral protein R | Aux, auxin | STAT, signal transducer and activator of transcription | CAND1, Cullin-associated NEDD8-dissociated protein 1 | Fbxo, F-box | TIR1, transport inhibitor response 1 | CBFβ, core binding factor β | BCR, BTB–Cul3–Rbx1 | cyclosome | SOCS, suppressor of cytokine signalling | NEDD, neural-precursor-cell-expressed developmentally down-regulated | BTB, bric-a-brac | APC | Cdc, cell division cycle | Cul, Cullin | SPOP, speckle-type POZ protein | β-TrCP, β-transducin repeat-containing protein | tramtrack | ASB, ankyrin repeat and SOCS-box
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2013, Volume 31, Issue 34, pp. 4333 - 4342
Journal Article
Annual review of biochemistry, ISSN 0066-4154, 6/2017, Volume 86, Issue 1, pp. 685 - 714
... >1,000 different mitochondrial proteins are synthesized as precursors in the cytosol and are imported into mitochondria by five transport pathways... 
outer membrane | mitochondrial architecture | inner membrane | protein sorting | translocase | preprotein | Inner membrane | Preprotein | Protein sorting | Translocase | Outer membrane | Mitochondrial architecture | RESPIRATORY-CHAIN | DISULFIDE RELAY SYSTEM | PRESEQUENCE TRANSLOCASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SMALL TIM PROTEINS | CYTOCHROME-C REDUCTASE | TAIL-ANCHORED PROTEINS | OUTER-MEMBRANE PROTEINS | BETA-BARREL PROTEINS | INNER-MEMBRANE | INTERMEMBRANE SPACE PROTEINS | Protein Precursors - chemistry | Humans | Eukaryotic Cells - metabolism | Isoenzymes - chemistry | Mitochondrial Proteins - genetics | Mitochondria - ultrastructure | Mitochondrial Membrane Transport Proteins - genetics | Organelle Biogenesis | Isoenzymes - metabolism | Mitochondrial Proteins - metabolism | Eukaryotic Cells - ultrastructure | Carrier Proteins - chemistry | Protein Conformation, alpha-Helical | Gene Expression | Mitochondrial Membrane Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - metabolism | Protein Precursors - genetics | Isoenzymes - genetics | Mitochondria - metabolism | Mitochondrial Membranes - metabolism | Protein Precursors - metabolism | Protein Transport | Carrier Proteins - genetics | Carrier Proteins - metabolism | Protein Conformation, beta-Strand | Mitochondrial Membranes - ultrastructure | Mitochondrial Proteins - chemistry | Physiological aspects | Mitochondria | Genetic aspects | Research | Carrier proteins
Journal Article