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Movement Disorders, ISSN 0885-3185, 09/2014, Volume 29, Issue 10, pp. 1281 - 1288
Cognitive dysfunction is central to Huntington's disease (HD) and undermines quality of life. Clinical trials are now targeting cognitive outcomes in HD;... 
neuropsychology | practice effects | cognitive assessment | premanifest Huntington's disease | early Huntington's disease | DIAGNOSIS | PREMANIFEST | CLINICAL NEUROLOGY
Journal Article
Movement Disorders, ISSN 0885-3185, 08/2018, Volume 33, Issue 8, pp. 1370 - 1371
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, p. 16742
Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disorder, and no cure is available currently. Treatment of HD is likely to be... 
NETWORK | MULTIDISCIPLINARY SCIENCES | MICE | ANESTHETICS | FMRI RESPONSES | PREMANIFEST | ONSET
Journal Article
Frontiers in Systems Neuroscience, ISSN 1662-5137, 10/2014, Volume 8
Motor slowing and forebrain white matter loss have been reported in premanifest Huntington’s disease (HD) prior to substantial striatal neuron loss. These... 
Pathology | Corticostriatal | Huntington’s disease | Thalamostriatal | Premanifest | corticostriatal | premanifest | thalamostriatal
Journal Article
Neurobiology of disease, ISSN 0969-9961, 12/2013, Volume 60
Motor slowing, forebrain white matter loss, and striatal shrinkage have been reported in premanifest Huntington’s disease (HD) prior to overt striatal neuron... 
Pathology | Huntington’s Disease | Corticostriatal | Thalamostriatal | Premanifest
Journal Article
International Journal of Neuroscience, ISSN 0020-7454, 06/2019, Volume 129, Issue 6, pp. 563 - 572
Background: Cognitive abnormalities in Huntington's Disease (HD) can involve the specific impairment of the social perspective taking as well as difficulties... 
early diagnosis | emotional valence | Reading the Mind in the Eyes test | manifest and premanifest patients | Mental state recognition in Huntington's disease | EYES TEST | NATURAL-HISTORY | PREMANIFEST | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | IMPAIRMENT | MIND | EMOTION RECOGNITION | FACIAL EMOTIONS | ONSET
Journal Article
Current Opinion in Neurology, ISSN 1350-7540, 2014, Volume 27, Issue 4, pp. 477 - 483
Purpose of review This review highlights the recent advances in Huntington's disease, with a particular focus on development of disease biomarkers for use in... 
neurodegeneration | premanifest Huntington's disease | prodromal Huntington's disease | biomarker | Huntington's disease | TRACK-HD | MUTANT HUNTINGTIN | PREMANIFEST | NEUROSCIENCES | CLINICAL NEUROLOGY | OBSERVATIONAL DATA | MOUSE MODEL | MOTOR | LATE-ONSET | MICE | DYSFUNCTION | Huntington Disease - therapy | Huntington Disease - genetics | Humans | Huntington Disease - physiopathology
Journal Article
PLOS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease whose predominant neuropathological signature is the selective loss of medium... 
HEPATIC MITOCHONDRIAL DYSFUNCTION | MICROGLIAL ACTIVATION | INSTABILITY | MULTIDISCIPLINARY SCIENCES | MICE | PATHOLOGY | PREMANIFEST | EXPRESSION | REPEATS | BRAIN | ONSET
Journal Article
Journal Article
European Journal of Neurology, ISSN 1351-5101, 08/2011, Volume 18, Issue 8, pp. 1105 - 1108
Background:  The P3 event‐related potential (ERP) is presumably partly generated by the basal ganglia. Because degeneration of these brain structures starts... 
premanifest | Huntington’s disease | basal ganglia
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, p. 6634
Huntington's disease (HD) is a devastating hereditary movement disorder, characterized by degeneration of neurons in the striatum and cortex. Studies in human... 
CAG REPEAT | VISUAL-CORTEX | MULTIDISCIPLINARY SCIENCES | DENDRITIC SPINE | NEURONS | TRANSGENIC MOUSE MODEL | DEFICITS | PREMANIFEST | INTERNEURONS | REVEALS
Journal Article
Journal Article
Psychiatry Research: Neuroimaging, ISSN 0925-4927, 09/2019, Volume 291, pp. 1 - 8
We aimed to investigate the relationship between striatal morphology in Huntington disease (HD) and measures of motor and cognitive dysfunction. MRI scans,... 
Biomarker Huntington disease | Neostriatum | Endophenotype | PSYCHIATRY | ATROPHY | BASAL GANGLIA | RELIABILITY | PREMANIFEST | NEUROIMAGING | CLINICAL NEUROLOGY | NUCLEUS | INTERFERENCE | SCALE
Journal Article
The Journal of comparative neurology, ISSN 0021-9967, 12/2016, Volume 524, Issue 17, pp. 3518 - 3529
We have previously found that thalamostriatal axodendritic terminals are reduced as early as 1 month of age in heterozygous Q140 HD mice ( Deng et al., 2013 ).... 
Cholinergic Interneurons | Pathology | Striatum | AB_2301731 | AB_90650 | Premanifest | Huntington’s disease | Corticostriatal | Thalamostriatal
Journal Article
Neuropsychologia, ISSN 0028-3932, 01/2020, Volume 136, p. 107262
Journal Article
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