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Molecular Cell, ISSN 1097-2765, 08/2013, Volume 51, Issue 3, pp. 338 - 348
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2010, Volume 39, Issue 6, pp. 925 - 938
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 22, pp. 10020 - 10025
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 423 - 432.e4
Accurate pre-mRNA splicing is needed for correct gene expression and relies on faithful splice site recognition. Here, we show that the ubiquitin-like protein... 
Prp5 | splicing fidelity | UBL5 | DEAD-box helicase | spliceosome assembly | ubiquitin-related protein | Hub1 | pre-mRNA splicing | FISSION YEAST | PRP5 | TRANSLATIONAL TERMINATION CODON | PROTEIN HUB1 | SMALL NUCLEAR-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPLICEOSOME | PREMESSENGER RNA | IDENTIFICATION | PRE-MESSENGER-RNA | SNRNP | CELL BIOLOGY | Spliceosomes - genetics | Saccharomyces cerevisiae - genetics | Ligases - genetics | Structure-Activity Relationship | Ligases - chemistry | RNA, Messenger - metabolism | Spliceosomes - metabolism | RNA Splicing | Time Factors | Adenosine Triphosphate - metabolism | RNA Precursors - metabolism | RNA, Fungal - genetics | DEAD-box RNA Helicases - metabolism | Binding Sites | Gene Expression Regulation, Fungal | RNA Splice Sites | RNA, Messenger - genetics | Ligases - metabolism | Models, Molecular | RNA Precursors - genetics | Saccharomyces cerevisiae Proteins - genetics | RNA, Fungal - metabolism | Hydrolysis | DEAD-box RNA Helicases - genetics | Feedback, Physiological | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Saccharomyces cerevisiae - enzymology | Protein Conformation | Mutation | Saccharomyces cerevisiae Proteins - chemistry | Ubiquitin | DNA replication | Messenger RNA | Biological products | Genomics | Gene expression | Cells | Adenosine triphosphatase | Protein binding | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 12/2007, Volume 28, Issue 5, pp. 838 - 849
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e78172 - e78172
Journal Article
Science, ISSN 0036-8075, 01/2017, Volume 355, Issue 6321, pp. 149 - 155
Each cycle of precursor messenger RNA (pre-mRNA) splicing comprises two sequential reactions, first freeing the 5' exon and generating an intron lariat-3' exon... 
METAL-ION CATALYSIS | SPLICING FACTOR PRP18 | ATP HYDROLYSIS | 1ST STEP | CONFORMATIONAL REARRANGEMENT | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CROSS-LINKING | PREMESSENGER RNA | SMALL NUCLEAR RNAS | PRE-MESSENGER-RNA | Saccharomyces cerevisiae Proteins - ultrastructure | Spliceosomes - chemistry | Catalytic Domain | Biocatalysis | Exons | Cell Cycle Proteins - ultrastructure | RNA Splicing Factors - chemistry | Saccharomyces cerevisiae - ultrastructure | Spliceosomes - ultrastructure | Ribonucleoprotein, U4-U6 Small Nuclear - ultrastructure | DNA-Binding Proteins - chemistry | Amino Acid Motifs | Cell Cycle Proteins - chemistry | Cryoelectron Microscopy | DNA-Binding Proteins - ultrastructure | Saccharomyces cerevisiae - metabolism | RNA Splicing | RNA Splicing Factors - ultrastructure | Ribonucleoprotein, U4-U6 Small Nuclear - chemistry | Ribonucleoprotein, U5 Small Nuclear - ultrastructure | Ribonucleoprotein, U5 Small Nuclear - chemistry | Saccharomyces cerevisiae Proteins - chemistry | RNA sequencing | Physiological aspects | Genetic aspects | Messenger RNA | Yeast fungi | Methods | Proteins | Macromolecules | Ribonuclease H | mRNA | Transesterification | Catalysis | Electron microscopy | Splicing factors | Intermediates | Index Medicus | Pictures | Splicing | Ribonucleic acids | Catalysts | Coding | Precursors
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2019, Volume 47, Issue 2, pp. 899 - 910
Abstract The spliceosome is assembled via sequential interactions of pre-mRNA with five small nuclear RNAs and many proteins. Recent determination of cryo-EM... 
GU DINUCLEOTIDE | SITE | 1ST STEP | U5 SNRNP | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPLICEOSOME | CROSS-LINKING | PREMESSENGER RNA | PRP8 PROTEIN | CRYO-EM STRUCTURE | PRE-MESSENGER-RNA | RNA and RNA-protein complexes
Journal Article
Journal Article