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Nature Cell Biology, ISSN 1465-7392, 03/2015, Volume 17, Issue 3, pp. 228 - 240
Membrane association with mother centriole (M-centriole) distal appendages is critical for ciliogenesis initiation. How the Rab GTPase Rab11-Rab8 cascade... 
EHD PROTEINS | TRANSPORT | COMPLEX | BIOGENESIS | PRIMARY CILIOGENESIS | MEMBRANE | DOCKING | GTPASE RAB8 | DISTINCT ROLES | MOTHER CENTRIOLE | CELL BIOLOGY | RNA, Small Interfering - genetics | Retinal Pigment Epithelium - metabolism | Epithelial Cells - metabolism | Axoneme - metabolism | Vesicular Transport Proteins - metabolism | Humans | Qb-SNARE Proteins - metabolism | Qb-SNARE Proteins - genetics | rab GTP-Binding Proteins - genetics | Vesicular Transport Proteins - antagonists & inhibitors | Qc-SNARE Proteins - metabolism | Retinal Pigment Epithelium - ultrastructure | Axoneme - ultrastructure | Gene Expression Regulation, Developmental | Cilia - ultrastructure | Centrioles - ultrastructure | rab GTP-Binding Proteins - metabolism | Cell Line | Kidney Tubules, Collecting - ultrastructure | Morphogenesis - genetics | Signal Transduction | Vesicular Transport Proteins - genetics | Carrier Proteins - antagonists & inhibitors | Epithelial Cells - ultrastructure | Zebrafish | Cilia - metabolism | Carrier Proteins - genetics | Kidney Tubules, Collecting - metabolism | Animals | Carrier Proteins - metabolism | Transport Vesicles - metabolism | Embryo, Nonmammalian | Qc-SNARE Proteins - genetics | Mice | Centrioles - metabolism | Transport Vesicles - ultrastructure | RNA, Small Interfering - metabolism | Cell research | Cilia and ciliary motion | Physiological aspects | Cell organelles | Research | Properties | Formation | Membrane proteins | Index Medicus
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 08/2019, Volume 29, Issue 8, pp. 607 - 608
Rab11 and its interacting partners play a crucial role in primary cilia assembly in mammalian cells. A recent study (Walia , , 2019) describes an as yet... 
primary cilium | Rab11 | WDR44 | RAB11 | PROTEIN | CELL BIOLOGY | Medicine, Experimental | Medical research | Binding proteins | Developmental biology | Cells | Protein binding | AKT protein | Membrane trafficking | Cilia | Mammalian cells
Journal Article
Journal of cell science, ISSN 0021-9533, 2018, Volume 131, Issue 24, p. jcs219527
Primary cilia are antenna-like sensory organelles that transmit various extracellular signals. Ciliogenesis requires the removal of CP110 and its interactor... 
Cullin-3 | CEP97 | KCTD10 | Primary cilia | CP110 | Ubiquitylation | LOCALIZATION | CENTRIOLES | PROTEIN | UBIQUITIN LIGASE | CONTROLS CENTROSOME HOMEOSTASIS | ADAPTERS | CELL BIOLOGY | CULLIN | CILIOGENESIS | BINDING
Journal Article
Developmental Cell, ISSN 1534-5807, 03/2014, Volume 28, Issue 6, pp. 647 - 658
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2018, Volume 34, Issue 1, pp. 69 - 84.e14
Human melanomas frequently harbor amplifications of . However, the contribution of EZH2 to melanoma formation has remained elusive. Taking advantage of murine... 
primary cilium | PRC2 | metastasis | melanoma | WNT/β-catenin signaling | tumor initiation | epigenetics | EZH2 | CELLS | DEFECTS | ONCOLOGY | TRANSCRIPTION | MELANOCYTIC LESIONS | MUTATIONS | TRANSGENIC MOUSE MODEL | BETA-CATENIN | EXPRESSION | CANCER | CELL BIOLOGY | Prevention | Epigenetic inheritance | Analysis | Melanoma | Stem cells | Metastasis | Cancer | Index Medicus
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2018, Volume 131, Issue 24, p. jcs219923
Loss of the gene von Hippel-Lindau (VHL) is associated with loss of primary cilia and is causally linked to elevated levels of Aurora kinase A (AURKA). We... 
Bexarotene | VHL | Primary cilia | Primary HTS screen | AURKA | RNA-POLYMERASE-II | VON-HIPPEL-LINDAU | BINDING-PROTEIN | 13-CIS-RETINOIC ACID | LARGE SUBUNIT | CELL BIOLOGY | INTERFERON ALPHA-2A | 9-CIS RETINOIC ACID | PROLINE HYDROXYLATION | TUMOR-SUPPRESSOR PROTEIN | NONGENOMIC ACTIONS | 136
Journal Article
Journal of Cutaneous Pathology, ISSN 0303-6987, 09/2019, Volume 46, Issue 9, pp. 665 - 671
A eukaryotic cell's primary cilium (PC) is critical for cell signaling, migration and homeostasis. Primary cilium dysfunction has been demonstrated in several... 
acral nevi | dermatopathology | primary cilium | primary cilia | medical dermatology | melanoma | acral melanoma | acral nevus | CELLS | SUBTYPES | BRAF | PATHOLOGY | CANCER | DERMATOLOGY | KIT | MUTATIONS | EXPRESSION | BURDEN | Immunohistochemistry | Medical colleges | Melanoma | Statistical analysis | Biopsy | Benign | Homeostasis | Melanocytes | Sox10 protein | Cell migration | Cilia | Index Medicus
Journal Article
Genes and Development, ISSN 0890-9369, 2009, Volume 23, Issue 16, pp. 1910 - 1928
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2017, Volume 16, Issue 9, pp. 817 - 818
Journal Article
Cilia, ISSN 2046-2530, 04/2012, Volume 1, Issue 1, pp. 4 - 4
Polarized vesicle trafficking is mediated by small GTPase proteins, such as Rabs and Arls/Arfs. These proteins have essential roles in maintaining normal... 
Ciliopathies | Primary cilium | Intraflagellar transport | Ciliary signaling | Trafficking | Proteins | Cellular proteins | Cellular signal transduction | Cilia and ciliary motion
Journal Article
FRONTIERS IN GENETICS, ISSN 1664-8021, 03/2019, Volume 10, pp. 163 - 163
The primary cilium is able to maintain a specific protein composition, which is critical for its function as a signaling organelle. Here we introduce a system... 
primary cilium | protein trafficking | MEMBRANE | GENETICS & HEREDITY | epithelial cells | somatostatin receptor 3 | nephrocystin-3 | DIFFUSION BARRIER | ADAPTERS | CILIARY TRAFFICKING | REVEALS | BASE | Proteins | Usage | Cell membranes | Research | Somatostatin | Cilia and ciliary motion
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1116 - 1116
The primary cilium is a single non-motile protrusion of the plasma membrane of most types of mammalian cell. The structure, length and function of the primary... 
TRANSPORT | PROTEIN | PRIMARY CILIOGENESIS | MEMBRANE | MULTIDISCIPLINARY SCIENCES | DISEASE | TRAFFICKING | ACTIN CYTOSKELETON | CAVEOLAE | AUTOPHAGY | CELL
Journal Article