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The New England Journal of Medicine, ISSN 0028-4793, 08/2018, Volume 379, Issue 7, pp. 689 - 690
In primary effusion lymphoma, a herpesvirus 8 (HHV-8)–associated neoplasm that is most common in HIV-coinfected patients, cells often express CD38. In a... 
Flow cytometry | Antiretroviral drugs | Medical imaging | Effusion | Multiple myeloma | Disclosure | Patients | Chemotherapy | Human immunodeficiency virus--HIV | Medical prognosis | CD38 antigen | Bone marrow | Lymphomas | Primary effusion lymphoma
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2013, Volume 123, Issue 6, pp. 2616 - 2628
Primary effusion lymphoma (PEL) is a rare form of aggressive B cell lymphoma caused by Kaposi's sarcoma-associated herpesvirus (KSHV). Current chemotherapy... 
MULTIPLE-MYELOMA | MEDICINE, RESEARCH & EXPERIMENTAL | VIRAL GENE-EXPRESSION | DNA-SEQUENCES | KAPOSIS-SARCOMA | SARCOMA-ASSOCIATED HERPESVIRUS | HISTONE DEACETYLASE INHIBITORS | BINDING PROTEIN | NF-KAPPA-B | LYTIC REPLICATION | LANA PROTEIN | Herpesvirus 8, Human - drug effects | Humans | Pyrazines - administration & dosage | Histone Deacetylase Inhibitors - administration & dosage | Lymphoma, Primary Effusion - virology | Virus Latency - drug effects | Antineoplastic Combined Chemotherapy Protocols - pharmacology | HEK293 Cells | Hydroxamic Acids - administration & dosage | Boronic Acids - administration & dosage | Herpesvirus 8, Human - physiology | Bortezomib | Proteasome Inhibitors - administration & dosage | Tumor Suppressor Protein p53 - metabolism | Mitochondria - drug effects | Herpesviridae Infections - virology | Mice, SCID | Proto-Oncogene Proteins c-myc - metabolism | Herpesviridae Infections - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Virus Replication | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cell Cycle Checkpoints - drug effects | Vorinostat | Lymphoma, Primary Effusion - drug therapy | Cell Line, Tumor | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Histones - metabolism | Apoptosis | Care and treatment | Usage | Physiological aspects | Lymphomas | Drug therapy, Combination | Research | Ubiquitin-proteasome system | Health aspects | Proteins | Plasmids | Kaposis sarcoma | Cell cycle
Journal Article
British Journal of Haematology, ISSN 0007-1048, 01/2018, Volume 180, Issue 1, pp. 9 - 9
Journal Article
Oncogene, ISSN 0950-9232, 05/2014, Volume 33, Issue 22, pp. 2928 - 2937
Primary effusion lymphoma (PEL) is an aggressive form of non-Hodgkin's B-cell lymphoma associated with infection by Kaposi's sarcoma-associated herpes virus... 
BET | bromodomain | KSHV | Myc | PEL | SELECTIVE-INHIBITION | RNA INTERFERENCE | NUCLEAR ANTIGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | SARCOMA-ASSOCIATED HERPESVIRUS | C-MYC | CANCER | CELL BIOLOGY | ONCOLOGY | GENETICS & HEREDITY | LATENCY | TERMINAL REPEAT | EXPRESSION | BRD4 | Apoptosis - drug effects | Humans | Cell Survival - genetics | Cellular Senescence - drug effects | Herpesvirus 8, Human | Lymphoma, Primary Effusion - virology | Heterocyclic Compounds, 4 or More Rings - pharmacology | Dose-Response Relationship, Drug | Cell Nucleus - metabolism | Protein Binding - drug effects | Inhibitory Concentration 50 | Female | Transcription, Genetic | Antineoplastic Agents - pharmacology | Lymphoma, Primary Effusion - genetics | Gene Expression Regulation, Neoplastic - genetics | Disease Models, Animal | Lymphoma, Primary Effusion - metabolism | Cell Survival - drug effects | Virus Replication - drug effects | Lymphoma, Primary Effusion - pathology | Transcription Factors - antagonists & inhibitors | Proto-Oncogene Proteins c-myc - metabolism | Protein Transport | Azepines - pharmacology | Triazoles - pharmacology | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Cell Cycle Checkpoints - drug effects | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Cell Proliferation - drug effects | Proto-Oncogene Proteins c-myc - genetics | Development and progression | Care and treatment | Lymphomas | Properties | Genes | Proteins | Gene expression | Herpes viruses | Kaposis sarcoma | Apoptosis | Bromodomain
Journal Article
Annals of Diagnostic Pathology, ISSN 1092-9134, 2012, Volume 16, Issue 6, pp. 441 - 446
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 03/2017, Volume 41, pp. 124 - 136
Quercetin, a bioflavonoid contained in several vegetables daily consumed, has been studied for long time for its antiinflammatory and anticancer properties.... 
mTOR/PI3K/AKT | KSHV | PEL | Il-6 | Quercetin | STAT3 | CANCER-CELLS | RAPAMYCIN | mTOR/PI3K/AKF | ACTIVATION | SURVIVIN EXPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | II-6 | MAJOR HISTOCOMPATIBILITY COMPLEX | KINASE INHIBITOR | KAPPA-B | NUTRITION & DIETETICS | WNT/BETA-CATENIN | GROWTH | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Proteasome Inhibitors - chemistry | Neoplasm Proteins - antagonists & inhibitors | Bortezomib - pharmacology | Neoplasm Proteins - metabolism | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | Interleukins - metabolism | Drug Agonism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Antineoplastic Agents, Phytogenic - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Phosphatidylinositol 3-Kinase - metabolism | B-Lymphocytes - metabolism | STAT3 Transcription Factor - metabolism | Antineoplastic Agents, Phytogenic - adverse effects | Lymphoma, Primary Effusion - metabolism | B-Lymphocytes - cytology | Proteasome Inhibitors - pharmacology | Cells, Cultured | Lymphoma, Primary Effusion - pathology | Recombinant Fusion Proteins - chemistry | Antineoplastic Agents - chemistry | Down-Regulation - drug effects | Interleukins - antagonists & inhibitors | B-Lymphocytes - drug effects | B-Lymphocytes - immunology | Lymphoma, Primary Effusion - immunology | Signal Transduction - drug effects | Lymphoma, Primary Effusion - drug therapy | Quercetin - adverse effects | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | STAT3 Transcription Factor - antagonists & inhibitors | Bortezomib - agonists | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Quercetin - metabolism | Cellular proteins | Flavonoids | Flavones | Sarcoma | Bioflavonoids | Lymphomas | B cells | Apoptosis
Journal Article
Journal Article