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Annual Review of Pathology: Mechanisms of Disease, ISSN 1553-4006, 1/2017, Volume 12, Issue 1, pp. 153 - 186
Liver cancer is the second leading cause of cancer mortality worldwide, causing more than 700,000 deaths annually. Because of the wide landscape of genomic... 
fluke | primary sclerosing cholangitis (PSC) | stiffness | inflammation | stroma | mechanosensitive signaling | Stroma | Mechanosensitive signaling | Inflammation | Primary sclerosing cholangitis (PSC) | Stiffness | Fluke | Physiological aspects | Fibroblasts | Liver cancer | Health aspects | Cancer cells
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2510 - 15
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 39, pp. 64954 - 64963
Journal Article
Nature Medicine, ISSN 1078-8956, 2017, Volume 23, Issue 12, pp. 1424 - 1435
Human liver cancer research currently lacks in vitro models that can faithfully recapitulate the pathophysiology of the original tumor. We recently described a... 
MEDICINE, RESEARCH & EXPERIMENTAL | CHOLANGIOCARCINOMA | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | ESTABLISHMENT | GENOME | CELL BIOLOGY | HEPATOCELLULAR-CARCINOMA | IN-VITRO EXPANSION | ADULT LIVER | EXPRESSION | INACTIVATING MUTATIONS | Cell Proliferation | Primary Cell Culture - methods | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Male | Antineoplastic Agents - therapeutic use | Carcinoma, Hepatocellular - drug therapy | Antineoplastic Agents - isolation & purification | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Bile Duct Neoplasms - genetics | Tumor Cells, Cultured | Bile Duct Neoplasms - drug therapy | Precision Medicine | Drug Screening Assays, Antitumor - methods | Organoids - pathology | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | Mice, SCID | Xenograft Model Antitumor Assays | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - drug therapy | Carcinoma, Hepatocellular - pathology | Cholangiocarcinoma - genetics | Mice, Inbred NOD | Mice | Bile Duct Neoplasms - pathology | Cell culture | Liver cancer | Development and progression | Usage | Models | Research | Propagation | Liver | Hepatocellular carcinoma | Tissues | Drug screening | Metastases | Utilities | Biomedical materials | Organoids | Xenografts | Bioindicators | Cholangiocarcinoma | Extracellular signal-regulated kinase | Cultures | Pharmacology | Gene expression | Chemical compounds | Screening | Hepatocytes | Biomarkers | In vivo methods and tests | Tumors | Cancer | Index Medicus
Journal Article