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1. Full Text The Role of Cancer-Associated Fibroblasts and Fibrosisin Liver Cancer
by Affo, Silvia and Yu, Le-Xing and Schwabe, Robert F
Annual Review of Pathology: Mechanisms of Disease, ISSN 1553-4006, 1/2017, Volume 12, Issue 1, pp. 153 - 186
Liver cancer is the second leading cause of cancer mortality worldwide, causing more than 700,000 deaths annually. Because of the wide landscape of genomic... 
fluke | primary sclerosing cholangitis (PSC) | stiffness | inflammation | stroma | mechanosensitive signaling | Stroma | Mechanosensitive signaling | Inflammation | Primary sclerosing cholangitis (PSC) | Stiffness | Fluke | Physiological aspects | Fibroblasts | Liver cancer | Health aspects | Cancer cells
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2. Full Text CHML promotes liver cancer metastasis by facilitating Rab14 recycle
by Chen, Tian-Wei and Yin, Fen-Fen and Yuan, Yan-Mei and Guan, Dong-Xian and Zhang, Erbin and Zhang, Feng-Kun and Jiang, Hao and Ma, Ning and Wang, Jing-Jing and Ni, Qian-Zhi and Qiu, Lin and Feng, Jing and Zhang, Xue-Li and Bao, Ying and Wang, Kang and Cheng, Shu-Qun and Wang, Xiao-Fan and Wang, Xiang and Li, Jing-Jing and Xie, Dong
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2510 - 15
Metastasis-associated recurrence is the major cause of poor prognosis in hepatocellular carcinoma (HCC), however, the underlying mechanisms remain largely... 
Neoplasm Transplantation | Neoplasms, Multiple Primary - metabolism | Humans | Lung Neoplasms - metabolism | Carcinoma, Hepatocellular - secondary | RNA, Messenger - metabolism | Lung Neoplasms - secondary | Carcinoma, Hepatocellular - genetics | HEK293 Cells | Hyaluronan Receptors - metabolism | Mucins - metabolism | Liver Neoplasms - pathology | rab GTP-Binding Proteins - metabolism | Liver Neoplasms - genetics | Neoplasm Recurrence, Local - metabolism | Neoplasm Invasiveness | Tumor Burden | Neoplasms, Multiple Primary - pathology | Animals | Mice, Nude | Adaptor Proteins, Signal Transducing - genetics | Liver Neoplasms - metabolism | Neoplasm Recurrence, Local - genetics | Mice | Adaptor Proteins, Signal Transducing - metabolism | Carcinoma, Hepatocellular - metabolism | Liver cancer | Regulators | CD44 antigen | Therapeutic applications | Medical prognosis | Hepatocellular carcinoma | Metastasis | Cell migration | Nodules | Metastases | Index Medicus
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3. Full Text Marital status and survival in patients with primary liver cancer
by He, Xing-Kang and Lin, Zheng-Hua and Qian, Yun and Xia, Daheng and Jin, Piaopiao and Sun, Lei-Min
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 39, pp. 64954 - 64963
Background: Marital status is viewed as an independent prognostic factor for survival in various cancer types. However, its role in primary liver cancer has... 
Survival analysis | Marital status | Primary liver cancer | Surveillance | Epidemiology and end results | MORTALITY | POPULATION | epidemiology and end results | CELL BIOLOGY | BREAST-CANCER | HEPATOCELLULAR-CARCINOMA | survival analysis | marital status | DIURNAL CORTISOL RHYTHM | PSYCHOLOGICAL DISTRESS | SOCIAL SUPPORT | surveillance | HEALTH | primary liver cancer | EPIDEMIOLOGY | SEER DATABASE
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4. Full Text Human primary liver cancer-derived organoid cultures for disease modeling and drug screening
by Broutier, Laura and Mastrogiovanni, Gianmarco and Verstegen, Monique M.A and Francies, Hayley E and Gavarró, Lena Morrill and Bradshaw, Charles R and Allen, George E and Arnes-Benito, Robert and Sidorova, Olga and Gaspersz, Marcia P and Georgakopoulos, Nikitas and Koo, Bon-Kyoung and Dietmann, Sabine and Davies, Susan E and Praseedom, Raaj K and Lieshout, Ruby and IJzermans, Jan N.M and Wigmore, Stephen J and Saeb-Parsy, Kourosh and Garnett, Mathew J and Van Der Laan, Luc J.W and Huch, Meritxell
Nature Medicine, ISSN 1078-8956, 2017, Volume 23, Issue 12, pp. 1424 - 1435
Human liver cancer research currently lacks in vitro models that can faithfully recapitulate the pathophysiology of the original tumor. We recently described a... 
MEDICINE, RESEARCH & EXPERIMENTAL | CHOLANGIOCARCINOMA | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | ESTABLISHMENT | GENOME | CELL BIOLOGY | HEPATOCELLULAR-CARCINOMA | IN-VITRO EXPANSION | ADULT LIVER | EXPRESSION | INACTIVATING MUTATIONS | Cell Proliferation | Primary Cell Culture - methods | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Male | Antineoplastic Agents - therapeutic use | Carcinoma, Hepatocellular - drug therapy | Antineoplastic Agents - isolation & purification | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Bile Duct Neoplasms - genetics | Tumor Cells, Cultured | Bile Duct Neoplasms - drug therapy | Precision Medicine | Drug Screening Assays, Antitumor - methods | Organoids - pathology | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | Mice, SCID | Xenograft Model Antitumor Assays | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - drug therapy | Carcinoma, Hepatocellular - pathology | Cholangiocarcinoma - genetics | Mice, Inbred NOD | Mice | Bile Duct Neoplasms - pathology | Cell culture | Liver cancer | Development and progression | Usage | Models | Research | Propagation | Liver | Hepatocellular carcinoma | Tissues | Drug screening | Metastases | Utilities | Biomedical materials | Organoids | Xenografts | Bioindicators | Cholangiocarcinoma | Extracellular signal-regulated kinase | Cultures | Pharmacology | Gene expression | Chemical compounds | Screening | Hepatocytes | Biomarkers | In vivo methods and tests | Tumors | Cancer | Index Medicus
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