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Immunity, ISSN 1074-7613, 04/2015, Volume 42, Issue 4, pp. 665 - 678
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, pp. e0166433 - e0166433
Background Alternatively activated (M2) macrophages are phenotypically characterized by the expression of specific markers, mainly macrophage scavenger... 
EPITHELIAL-MESENCHYMAL TRANSITION | CANCER-CELLS | FIBROSIS | MULTIDISCIPLINARY SCIENCES | DISEASE | TISSUE-REPAIR | TUMOR-ASSOCIATED MACROPHAGES | SKIN | SYSTEMIC-SCLEROSIS | POLARIZATION | PLASTICITY | Antigens, CD - immunology | Tetradecanoylphorbol Acetate - pharmacology | Monocytes - cytology | Endothelin-1 - pharmacology | Humans | Lectins, C-Type - immunology | Matrix Metalloproteinase 9 - immunology | Monocytes - immunology | Receptor, Endothelin A - immunology | Lectins, C-Type - genetics | Antigens, CD - genetics | Transforming Growth Factor beta1 - immunology | Interleukin-4 - pharmacology | Chemokine CCL22 - immunology | Matrix Metalloproteinase 9 - genetics | Scavenger Receptors, Class A - genetics | Scavenger Receptors, Class A - immunology | Antigens, Differentiation, Myelomonocytic - immunology | Macrophages - immunology | Cell Line | Gene Expression Regulation | Transforming Growth Factor beta1 - genetics | Macrophages - cytology | Receptor, Endothelin A - genetics | Sulfonamides - pharmacology | Receptors, Cell Surface - immunology | Antigens, Differentiation, Myelomonocytic - genetics | Monocytes - drug effects | Chemokine CCL22 - genetics | Endothelin Receptor Antagonists - pharmacology | Phenotype | Mannose-Binding Lectins - genetics | Mannose-Binding Lectins - immunology | Cell Differentiation - drug effects | Interleukin-10 - genetics | Macrophages - drug effects | Primary Cell Culture | Macrophage Activation - drug effects | Interleukin-10 - immunology | Receptors, Cell Surface - genetics | Type 2 diabetes | Endothelin | Systemic scleroderma | Interleukins | Genes | Scleroderma (Disease) | Genetic aspects | Macrophages | Transforming growth factors | Gene expression | Sugars | Monosaccharides | Laboratories | Immunocytochemistry | Pathogenesis | Interleukin | Mannose | Cancer therapies | Sclerosis | Western blotting | Genotype & phenotype | Receptors | Interleukin 4 | Peripheral blood | Aging | Scavenger receptors | Metalloproteinase | Diabetes mellitus (non-insulin dependent) | Growth factors | Transforming growth factor-b1 | Cytokines | Internal medicine | Diabetes mellitus | Markers | Rheumatology | 12-O-Tetradecanoylphorbol-13-acetate | Cultures | Endothelin 1 | Gelatinase B | Polymerase chain reaction | Medicine | Studies | CD163 antigen | Monocytes | Systemic sclerosis | Interleukin 10 | Fibrosis | Acetic acid | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2015, Volume 290, Issue 1, pp. 46 - 55
Background: Glycolysis has an important role in inflammation. Results: MCT4 is up-regulated in inflammatorily activated macrophages and required for innate... 
AIRWAY EPITHELIAL-CELLS | LACTIC-ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | TOLL-LIKE RECEPTOR | EFFECTOR FUNCTION | Inflammation | Toll-like Receptor (TLR) | DENDRITIC CELL ACTIVATION | MCT4 | GLUCOSE-METABOLISM | AEROBIC GLYCOLYSIS | Glycolysis | PATTERN-RECOGNITION RECEPTORS | T-CELLS | Lipopolysaccharide (LPS) | Macrophage | INNATE IMMUNITY | Inflammation - pathology | Leukocytes, Mononuclear - metabolism | Toll-Like Receptor 2 - genetics | Humans | Glycolysis - genetics | Inflammation - metabolism | Monocarboxylic Acid Transporters - metabolism | Biological Transport | Leukocytes, Mononuclear - immunology | Muscle Proteins - metabolism | Myeloid Differentiation Factor 88 - immunology | Hexokinase - immunology | Hexokinase - genetics | Macrophages, Peritoneal - drug effects | Macrophages - immunology | Macrophages, Alveolar - immunology | Phosphofructokinase-2 - immunology | Muscle Proteins - immunology | Leukocytes, Mononuclear - drug effects | Signal Transduction | Lactic Acid - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Myeloid Differentiation Factor 88 - genetics | Macrophages, Peritoneal - immunology | Toll-Like Receptor 4 - genetics | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Immunity, Innate | Muscle Proteins - genetics | Feedback, Physiological | Macrophages - metabolism | Animals | Macrophages, Alveolar - drug effects | Phosphofructokinase-2 - genetics | Lipopolysaccharides - pharmacology | Inflammation - genetics | Toll-Like Receptor 2 - immunology | Macrophages - drug effects | Mice | Macrophages, Alveolar - metabolism | Monocarboxylic Acid Transporters - genetics | Primary Cell Culture | Macrophage Activation - drug effects | Macrophages, Peritoneal - metabolism | Monocarboxylic Acid Transporters - immunology | Glycolysis - immunology | Index Medicus | Immunology
Journal Article
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 11/2015, Volume 53, Issue 5, pp. 676 - 688
Macrophages are dynamic cells that mature under the influence of signals from the local microenvironment into either classically (M1) or alternatively (M2)... 
classically activated macrophages (CAM/M1) | Phagocytosis/ endocytosis | phagocytosis/endocytosis | phenotypic stability | alternatively activated macrophages (AAM/M2) | reprogramming of polarization | PHAGOCYTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOCYTES | DIFFERENTIAL REGULATION | MURINE | CELL BIOLOGY | GM-CSF | RESPIRATORY SYSTEM | THP-1 CELLS | MANNOSE | RECEPTOR-ACTIVITY | POLARIZATION | EXPRESSION | Chemokines, CC - secretion | Gene Expression - drug effects | Monocytes - cytology | Humans | Monocytes - immunology | Chemokine CCL5 - secretion | Chemokine CCL17 - secretion | Chemokine CXCL10 - biosynthesis | Interleukin-4 - pharmacology | Chemokine CCL17 - biosynthesis | Gene Expression - immunology | Chemokines, CC - biosynthesis | Interleukin-8 - secretion | Cell Differentiation | Interleukin-1beta - biosynthesis | Macrophages - immunology | Endocytosis - immunology | Interleukin-1beta - secretion | Interleukin-8 - biosynthesis | Endocytosis - drug effects | Tumor Necrosis Factor-alpha - secretion | Immunophenotyping | Macrophages - cytology | Interleukin-13 - pharmacology | Monocytes - drug effects | Chemokine CCL5 - biosynthesis | Chemokine CXCL10 - secretion | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Primary Cell Culture | Macrophage Activation - drug effects | Tumor Necrosis Factor-alpha - biosynthesis | Interferon-gamma - pharmacology | Studies | Biology | Immunology | Blood & organ donations | Cytokines | Gene expression | Index Medicus
Journal Article
Journal Article
Journal Article
Immunobiology, ISSN 0171-2985, 2017, Volume 222, Issue 8, pp. 900 - 912
Journal Article
Immunity, ISSN 1074-7613, 12/2017, Volume 47, Issue 6, pp. 1051 - 1066.e12
Human generated monocyte-derived dendritic cells (moDCs) and macrophages are used clinically, e.g., to induce immunity against cancer. However, their... 
NCOR2 | monocytes | macrophages | IL-4 activated macrophages | inflammatory dendritic cells | IL-4 | activation | human | monocyte-derived dendritic cells | M(IL-4) | inflammatory macrophages | IN-VITRO | HUMAN DENDRITIC CELLS | GM-CSF | MACROPHAGES | BONE-MARROW | PPAR-GAMMA | STEM-CELL | RECEPTOR | BLOOD MONOCYTES | IMMUNOLOGY | EXPRESSION | Monocytes - cytology | Dendritic Cells - immunology | Humans | Gene Expression Profiling | Monocytes - immunology | Signal Transduction - immunology | Interleukin-4 - pharmacology | Time Factors | Macrophage Colony-Stimulating Factor - pharmacology | Dendritic Cells - drug effects | Transcription, Genetic | Cell Differentiation | Interleukin-4 - genetics | Macrophages - immunology | Nuclear Receptor Co-Repressor 2 - genetics | Nuclear Receptor Co-Repressor 2 - immunology | Gene Expression Regulation | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Immunophenotyping | Macrophages - cytology | Macrophage Activation | Monocytes - drug effects | Cell Lineage | Interleukin-4 - immunology | Macrophages - drug effects | Dendritic Cells - cytology | Primary Cell Culture | Interleukins | Dendritic cells | Analysis | Genetic aspects | Genetic transcription | Macrophages | Cell differentiation | Transcription | Granulocyte-macrophage colony-stimulating factor | Colonies | Gene regulation | Interleukin | Differentiation (biology) | Humanin | Leukocytes (mononuclear) | Ontogeny | Immunity | Time dependence | Phagocytes | Signaling | Monocytes | Interleukin 4 | Specialization | Cellular biology | Phenotyping | Bone marrow | Colony-stimulating factor | Chemokines | Cancer | Index Medicus
Journal Article